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Evaluation of acceptance and commitment therapy for drug refractory epilepsy: a randomized controlled trial in South Africa--a pilot study.

PURPOSE: Psychological interventions in the treatment of epilepsy have been developed and evaluated for many years but the amount of research has hardly made an impact on how epilepsy is treated. The purpose of this study was to develop and evaluate a psychological treatment program consisting of acceptance and commitment therapy (ACT) together with some behavioral seizure control technology shown to be successful in earlier research. METHODS: The method consisted of a randomized controlled trial group design with repeated measures (n=27). All participants had an EEG verified epilepsy diagnosis with drug refractory seizures. Participants were randomized into one of two conditions, ACT or supportive therapy (ST). Therapeutic effects were measured by examining changes in quality of life (SWLS and WHOQOL) and seizure index (frequency x duration). Both treatment conditions consisted of only nine hours of professional therapy distributed in two individual and two group sessions during a four-week period. RESULTS: The results showed significant effects over all of the dependent variables for the ACT group as compared to the ST group at six- and twelve-month follow-ups. CONCLUSIONS: The results from this study suggest that a short-term psychotherapy program combined with anticonvulsant drugs may help to prevent the long-term disability that occurs from drug refractory seizures.

Adult↗

Taking a "leap of faith": acceptance and value of a cancer program-sponsored spiritual event.

Investigations of spiritual interventions for cancer patients are disproportionately few compared to the reported importance of religion to Americans. We report on the implementation and evaluation of a spiritual, community-based intervention developed with interdenominational community clergy. Approximately 1200 people attended a total of 3 gatherings: 2 at Roman Catholic and another at a Protestant Church. Respondents to questionnaires evaluating attendee characteristics and satisfaction (n = 209) were predominantly women (85%); 50% were patients and 45% were aged 60 years and older. Men were more likely to be currently under treatment for cancer, while women were more likely to be past patients or friends. Fewer than 2% felt anger or anxiety; attendees felt the service was very (90%) or somewhat (9.5%) helpful and expressed appreciation for cancer program clinician attendance and for hospital sponsorship of the event. Components in order of preference were prayer, music, Scripture, and litany. Logistic regression models reveal that music was most appreciated by previously treated patients, and prayer by currently treated patients. Secular healthcare systems can offer a religious service that comforts and links attendees to a broader community, including clergy and cancer program clinicians. Surveys can identify service components that appeal to differing groups and can facilitate service development.

Adolescent↗

Practitioner acceptance of the dofetilide risk-management program.

STUDY OBJECTIVE: To assess the opinions and knowledge retention of practitioners after participation in the dofetilide risk-management program. DESIGN: A 21-item questionnaire. SETTING: A large academic medical center. PARTICIPANTS: One hundred forty-six practitioners were given the questionnaire; 91 (62%) completed it. MEASUREMENTS AND RESULTS: The questionnaire assessed practitioners' opinions of the program and guidelines, preparation time for implementing dofetilide treatment, and retention of facts from the program. Responses were graded on a 5-point Likert scale. Practitioners took a mean of 0.86 +/- 0.44 hours to complete the program; physicians took the least time, pharmacists the most. Practitioners agreed the program was necessary but were undecided about whether the guidelines were easily understood or implemented. Nurses answered one of the two knowledge-retention questions incorrectly significantly more often than physicians or pharmacists. Identification of seven drugs that should not be taken with dofetilide differed significantly (p < 0.0001) across groups (mean accuracy score was 41% for nurses, 80% for pharmacists, and 86% for physicians). CONCLUSION: This risk-management program has been well received by practitioners at our institution. We are gathering data to determine whether the program is effective in reducing inappropriate administration of dofetilide.

Drug Information Services↗

Normalization of institutional mealtimes for profoundly retarded persons: effects and noneffects of teaching family-style dining.

Benefits have been reported for certain institutionalized populations when mealtimes are arranged under normal, family-style conditions. In this study, we evaluated a program for teaching family-style mealtime skills to institutionalized persons with skill deficits greater than those targeted in previous research--the profoundly retarded. Results showed that the program, involving forward chaining with a less-to-more intrusive prompting sequence and contingent reinforcement, successfully taught four profoundly retarded persons several family-style skills. Also, systematic measures supported the durability of the skills, social validity of the behavior changes, acceptance of the program by staff trainers, and no detrimental changes in health-related variables associated with food consumption. However, results also indicated that beneficial corollary changes (e.g., increased peer communication) previously reported with higher skilled populations did not occur. These results suggest that with more seriously handicapped populations, multiple changes should not be assumed when normalizing institutional conditions; rather, specific skill training will probably be necessary.

Adolescent↗

Acceptability of an Internet treatment decision support program for men with prostate cancer.

We have implemented a customized Internet decision support system designed to engage men in the decision-making process for the management of localized prostate cancer. The system is delivered to patients in the patient education room of the UWMC Prostate Oncology Center. The system interactively guides the patient through a series of surveys, and delivers multi-media interaction modeling and decision support output, both of which are customized for the patient's preferences. The system is currently implemented on an open source platform.

Decision Making↗

[Risk of developing coronary disease in relation to the level of education and type of work in a male population of Warsaw factories. III. Evaluation of the relation of the level of education and type of work and changes in the degree of risk during the conduction of a prevention program].

There was analyzed acceptation degree of popularized preventive rules according to the education level and the taking a part. Significant netto lowering of mean body mass, both blood pressures and values of multivariable logistic function (MLF) was obtained in the intervention group in comparison to the control one among mean with the elementary education. While in the group of persons with the secondary and university education lowering of mean body mass in persons with initially stated overweight, mean number of smoked cigarettes and the risk coefficient by Rose was obtained in the intervention group in comparison to the control one. Similarly, lowering of Rose's risk coefficient was observed in the intervention group of office workers in comparison to the central one, and significant netto lowering of mean body mass, systolic and diastolic blood pressure and multivariable logistic function (MLF) in the group of workers.

Administrative Personnel↗

Physician extenders in walk-in clinics: a prospective evaluation of the AMOSIST program.

The Automated Military Outpatient System (AMOS) Project was developed to improve the ambulatory care of patients with episodic and chronic illnesses. During the development of its episodic care component, the relative frequency of problems treated by the walk-in clinic staff was analyzed and showed a high volume of acute minor illnesses. A simple, conservative triage system run by non-professionals was developed to screen patients to a clinic for benign, self-limited illnesses run by physician-extenders. This group, the equivalent of civilian licensed practical nurses and nurses' aides, was trained in a task-oriented fashion to treat 44 common minor illnesses. Clinical algorithms for these illnesses were developed and used as training tools, memory aids, and auditing instruments. This program is now operating in 26 US Army hospitals and caring for some 44,000 patients a month in the continetal United States. We report the results of a prospective audit of the corpsmen and a study of the patient attitude and acceptance of the program.

Adult↗

Should elderly donors be accepted in a live related renal transplant program?

It is a matter of concern that the elderly donor may have increased risks in the peri-operative period due to age-related changes in various organ. Nephrosclerosis, atherosclerosis and low GFR of an elderly kidney may portend a poor graft outcome. A retrospective analysis of our live related renal transplant program (from June 1989 to December 1993) revealed that 27 of the donors were above 60 years of age. 21 of the recipients have been followed up for more than 1 year. These patients were compared with a cohort of 25 patients (donor age < 45 years) with similar HLA match, immunosuppressive protocol, and follow-up period more than 1 year. Graft survival at 1 year was 86% and 88% in the recipients from elderly and younger donors respectively; 1 patient in the control group died of fulminant sepsis. Mean follow-up was 21.6 months in the study group and 22.8 months in the control group. Allograft function was evaluated by serum creatinine and differential GFR by Tc DTPA scan. Serum creatinine (mg%) was 1.3 +/- 0.2 and 1.4 +/- 0.2 in the study group and 1.3 +/- 0.3, 1.2 +/- 0.3 in the control group at 3 and 12 months respectively. Glomerular filtration rate (ml/min) was 36.5 +/- 11.6 and 43.7 +/- 12.4 in the recipients from elderly donors whereas those from the younger donors had GFR (ml/min) of 40.6 +/- 9.6 and 49.6 +/- 14.2 at 3 and 12 months respectively, GFR continued to improve in both groups with follow-up. There was no difference in incidence or severity of ATN In the two groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[The sudden infant death syndrome. II. Its prevention by home monitoring].

Sudden infant death syndrome (SIDS) is a very dramatic situation with a very high incidence rate. Children with a high risk of SIDS can be identified by clinical/epidemiological scorings. The preventive usefulness of home monitoring is now a matter of study. Our experience is reported in this article. Thirty-nine infants at high risk were selected, although the monitoring program was finally achieved in only 36 cases. A cardiorespiratory impedance monitor (Centurion, Clinical Data, Boston, USA) was used. The tachycardia alarm was set at 200 b/min, bradycardia at 60 b/min and apnea > 20 seconds. The parents were trained in running the monitor and received technical support by phone during 24 hour per day. They filled out a daily record sheet with the observed anomalies. The mean time of monitoring was 8.2 months. After the withdrawal of the monitor, the parents answered a form with 26 questions. Twenty-four of the children needed, at least at some occasion, a light stimulation and 12 (33.3%) required a strong one. Meanwhile, the other 12 did not need any type of stimulus during monitoring. A simultaneous apnea/bradycardia alarm occurred in 17 cases. The home monitoring program was considered positive by the parents and only 4 families had technical difficulties. After the second week the fear and anxiety disappeared and only 1 family continued to be nervous throughout the monitoring program. The mean number of false alarms was 13.3/child, as opposed to 15.6 alarms due to apnea, 11.6 due to tachycardia and 0.9 due to apnea plus bradycardia. In conclusion, we think that home monitoring is easy, it reassures the families and their acceptance of the program is good.

Electrodes↗

Calculation of actuarial life tables with use of a microcomputer spreadsheet program.

PURPOSE: To simplify the calculation of the life-table method of survival analysis. MATERIALS AND METHODS: A template was developed for use with a popular microcomputer spreadsheet program to perform life-table survival calculations and to perform statistical comparisons between the survivals of groups of patients with use of the log-rank test. RESULTS: The template successfully performed life-table and log-rank calculations when compared with two standard, accepted statistical computing programs. CONCLUSION: The template can be used to quickly perform life-table calculations that can be used in the long-term follow-up of patients undergoing interventional radiologic procedures.

Female↗

Impact of blinded versus unblinded abstract review on scientific program content.

PURPOSE: A procedure whereby reviewers are not informed of the author or institutional identity for submitted abstracts is sometimes considered a more equitable and impartial process for selection of the content for a scientific program. We performed a prospective randomized study to evaluate the impact of a reviewer blinding process on scientific program content. MATERIALS AND METHODS: A total of 234 abstracts submitted for presentation at the 2001 meeting of the Southeastern Section of the American Urological Association were distributed for review and grading to 42 reviewers who were randomly assigned to either a blinded or unblinded category. Acceptance for presentation was based on combined raw scores for blinded and unblinded reviews. However, multiple statistical comparisons were performed to evaluate the program content if only the blinded or unblinded reviews had been used as criteria for program acceptance. The abstracts were divided into pediatrics; prostate cancer, bladder cancer and urinary diversion, female urology and urodynamics, endourology and laparoscopy, benign and malignant diseases of the kidney, and penis/erectile dysfunction and miscellaneous for review. RESULTS: Statistically significant differences were observed in the variability of scores for blinded versus unblinded reviewers in the bladder cancer and prostate cancer groups but not in the other categories. For the pediatrics and urodynamics/female urology groups unblinded reviewers had statistically significant higher mean scores than blinded reviewers but this was not observed in other categories. Overall there was no clear pattern showing greater or less variability between reviewers for blinded versus unblinded reviews, nor was there a consistently observed difference in mean raw scores. Of the papers included in the program 60% would have been accepted for presentation by either blinded or unblinded review alone. This figure increased to 80% when considering the papers which were most highly scored by reviewers in each category. CONCLUSIONS: Although this study cannot be used to determine the quality of reviews based on blinding versus unblinding, it does not demonstrate any consistent increase in variability between reviewers whether they have been informed of abstract authors and institution. Furthermore, there was no identifiable tendency for blinded or unblinded reviewers to assign higher or lower raw scores to abstracts. However, blinded versus nonblinded review may have a substantial impact on program content. Only 60% of the presented abstracts would have been chosen by either method used alone. Additionally, 20% of the 5 abstracts in each category graded most highly by 1 review process would not have been accepted for inclusion on the program by the other process. These data may not be applicable to other circumstances, but the blinding process for abstract review may impact substantially on program content for section meetings.

Abstracting and Indexing↗

Training basic teaching skills to community and institutional support staff for people with severe disabilities: a one-day program.

Shortcomings in the technology for training support staff in methods of teaching people with severe disabilities recently have resulted in calls to improve the technology. We evaluated a program for training basic teaching skills within one day. The program entailed classroom-based verbal and video instruction, practice, and feedback followed by on-the-job feedback. In Study I, four undergraduate interns participated in the program, and all four met the mastery criterion for teaching skills. Three teacher aides participated in Study 2, with results indicating that when the staff applied their newly acquired teaching skills, students with profound disabilities made progress in skill acquisition. Clinical replications occurred in Study 3, involving 17 staff in school classrooms, group homes, and an institution. Results of Studies 2 and 3 also indicated staff were accepting of the program and improved their verbal skills. Results are discussed regarding advantages of training staff in one day. Future research suggestions are offered, focusing on identifying means of rapidly training other teaching skills in order to develop the most effective, acceptable, and efficient technology for staff training.

Adolescent↗

Acceptance of the xylitol chewing gum regimen by preschool children and teachers in a Head Start program: a pilot study.

PURPOSE: This pilot study evaluated the acceptance and compliance of a xylitol chewing gum regimen by both children and classroom teachers in a Head Start program. METHODS: Thirty-five children chewed 100% xylitol gum (XyliFresh 100%, Leaf, Inc., 500 Field Dr., Lake Forest, IL 60045 U.S.A.) three times a day over a three week period. Children's acceptance was evaluated using a picture selection test. Teachers' acceptance was evaluated using a questionnaire. The children's and teachers' compliance was evaluated using a daily checklist that was completed by each teacher. RESULTS: Positive ratings were given for xylitol gum chewing (94%) and for taste (86%). Children's acceptance and compliance for chewing was excellent. Children chewed the gum at designated times and none of the children swallowed the gum. Teachers' acceptance of the chewing program was low. Three out of five participating teachers thought the gum chewing disturbed the classroom routine and four were not willing to participate in the program next year. Teachers' compliance was good and they followed by instructions during a three-week period. CONCLUSIONS: This study supports the suggestion that chewing xylitol gum is well accepted by children. Collaboration and education is essential to motivate teachers to adopt and supervise school-based prevention programs.

Attitude to Health↗

[Cardiac insufficiency--a rare major symptom of hypothyroidism in an infant].

A case of hypothyroidism in an infant who was born in an area where screening program was not accepted is presented. The diseases was recognized at the age of 5 months when the infant was admitted to hospital with pericarditis and heart failure - a rare complication in infant hypothyroidism. The possible mechanisms of the heart affection in hypothyroidism are reviewed. The necessity of hypothyroidism screening program is emphasized.

Female↗