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Nailfolds capillary abnormalities in polyvinyl chloride production workers.

In an unselected group of 120 Polish employees of a PCV production plant, nailfold capillaroscopic as well as general medical examination and some laboratory investigations (serum paper electrophoresis, IgA, IgG, IgM immunoglobulin concentration) were performed. Capillary abnormalities were seen in 48 persons (40%). No correlation with the length of occupational exposure, age and immunoglobulin concentration was found. The most frequent capillary patterns were the following: spastic changes with atonic component (18X) with giant Raynaud's loops in 10 of them, discrete spastic abnormalities (15X), scleroderma-like picture (12X) with a prevalence of short scattered capillaries and disarrangement of polarity. The percentage of persons with capillary abnormalities in this study (40%) is very similar to results described by Maricq (1976, 1978) in England (39.5%) and in the USA (36%).

Adult↗

Mortality study of workers in a polyvinyl-chloride production plant.

Age-standardised mortality-rates for a population of 2100 male workers exposed to vinyl chloride for periods of up to 27 years do not show any excess of total or cause-specific mortality. 1 case of angiosarcoma of the liver was identified just outside the study period. There was no suggestion of an increased frequency of deaths from the more common malignant diseases.

Adult↗