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Results for “PALATAL NEOPLASMS”

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At least 667 records · Page 37Linked to original sources
PubMed1983

Carcinoma of the maxillary sinus. A correlation of the clinical course with orbital involvement, pterygoid erosion or pterygopalatine invasion and cervical metastases.

A retrospective review of 112 cases treated by one author (J.C.) over the 21 year period 1953-1973 is performed. In 62% of the cases squamous cell carcinoma was the histologic diagnosis, with adenoid cystic carcinoma accounting for a further 16%. The remaining histologic types were few in number and included fibrosarcoma, muco-epidermoid carcinoma, melanoma, chondrosarcoma, adenocarcinoma, malignant Schwannoma, lymphosarcoma, malignant mixed tumor, rhabdomyosarcoma, angiosarcoma, and osteogenic sarcoma. Three years following diagnosis more than 1/3 of the squamous cell carcinomas were alive but by 10 years the survival rate had fallen to 16%. Orbital involvement at the time of presentation or noted at surgery had a poor prognosis with a 17% five year cure rate and only 2% alive at 10 years. Erosion of the pterygoids or pterygopalatine fossa invasion as diagnosed radiologically or intra-operatively revealed all patients dead of disease within five years despite radical surgery and irradiation. Cervical nodal metastases at primary presentation was a particularly ominous finding with all patients dead of disease within three years. Metastases developing later had a better prognosis with 39% surviving five years when treated aggressively.

Adolescent↗
PubMed1984

Carcinoma of the oropharynx: soft palate.

This article reviews the experience of The Princess Margaret Hospital in the management of squamous cell carcinoma of the soft palate and uvula. Between 1970 and 1979, 70 patients with this diagnosis received primary radiation therapy. The overall five year survival is 43%. The primary tumor was controlled in 80% by radiation. Advanced local (T3) and nodal (N2/3) disease proved difficult to control with radiation alone. The development of second malignancies in patients cured of their primary cancer remains a distressing problem.

Adult↗
PubMed1983

[Treatment of florid oral papillomatosis. Apropos of 10 cases].

Florid oral papillomatosis is a well defined, not exceptionally observed clinical entity of unknown pathogenesis. The exuberant lesions are characterized by their benign appearance on histology, but this is usually associated with a marked capacity for progression and recurrence and a tendency for epitheliomatous degeneration. Based on a review of cases in the published literature and a series of ten patients treated personally, it would appear that radiation therapy should be formally excluded, and that the treatment of choice is by wide excision associated, whenever possible, with reconstructive surgery.

Aged↗