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At least 667 records · Page 37Linked to original sources
PubMed1988

Falx ossification--MR visualization.

While falx calcification is rarely demonstrated using magnetic resonance, falx ossification, when seen, is characteristic. On magnetic resonance images, falx ossification exhibits a typical appearance consisting of a central marrow-containing portion with signal intensity similar to fat, surrounded by low signal intensity representing cortical bone. Falx ossification was seen in 0.7% of patients and should not be confused with a falx lipoma, a rare congenital entity.

Brain Diseases↗
PubMed1985

[Roentgenological and quantitative microradiographic study on ossification of posterior longitudinal ligament].

The purpose of this study was to reveal whether patients with OPLL had increased tendency of ossification in other tissues as well. Firstly patients with OPLL were classified according to radiological characteristics of ossification. Secondly transilial bone biopsy to iliac bone followed by Jowsey's microradiological analysis was performed in each patient with OPLL, patients with osteoporosis and normal individuals. The result is summarized as follows: OPLL is classified radiologically into three groups. Patients with OPLL tend to have ossification of other organs. The trabecular bone area in OPLL is significantly higher than normal and osteoporotic group. The resting surface of OPLL group is lower than normal and the turnover in OPLL is higher than normal group. The bone mineral content is more increased in OPLL group.

Adult↗
PubMed1983

[Total arthroplasty of the hip. Periarticular ossifications and ankylosing vertebral hyperostosis (Forestier's disease)].

A retrospective study was made on 536 patients in whom a Charnley-Muller total hip prosthesis had been inserted. Two hundred and seventeen cases were available for follow-up, 121 of them having signs of diffuse idiopathic skeletal hyperostosis (Forestier's Disease) which is common in the elderly. Peri-prosthetic ossification was found in 46 p. 100 of patients with hyperostosis and in only 24 p. 100 of patients without it (p = less than 0,01). In both groups the ossification was more frequent in men than in women (p = less than 0,001 in the hyperostosis group and less than 0,03 in the controlled group). In cases of bilateral prostheses, ossification was identical on both sides in 81 p. 100 of cases. Only 66 p. 100 of the men with hyperostosis obtained satisfactory postoperative hip mobility as against 83 p. 100 of men in the control group (p = 0,05). The difference was not significant in women. Pain was relieved in 93 p. 100 of patients with hyperostosis with no significant difference from the control group. It is concluded that the existence of diffuse idiopathic skeletal hyperostosis is not a contra-indication to total hip replacement provided that the main complaint of the patient is of pain.

Aged↗
PubMed1983

Cervical myelopathy due to ossification of the posterior longitudinal ligament.

Ossification of the posterior longitudinal ligament in the cervical spine may be a cause of cervical myelopathy. This ossification has often been encountered in Japan, but only sporadically among the Caucasian races. It is therefore probable that racial factors are relevant to the pathology. During the past four years, due to the routine use of computerised axial tomography (CAT) in the pre-operative study of cervical myelopathy, we were able to show that in 13 cases stenosis of the vertebral canal was due to ossification of the posterior longitudinal ligament. This was visible in the standard radiographs in only two out of these 13 cases. The clinical data, diagnostic criteria and results of treatment are reported. This is the largest series yet reported outside Japan.

Adult↗
PubMed1980

[Ossification of the Achilles tendon after surgery of talipes equinus in childhood and condition following Köhler II (author's transl)].

In a 48-year old man, ossification was seen in the right achilles tendon which was to be interpreted as due to surgical extension of tendon in childhood following operation of talipes equinus. Only few reports have been published in literature, but in these, the x-ray findings were largely identical, and in all cases except one, injuries of the tendon or operations had preceded the condition. Ossification is associated with mild complaints only. It presents a typical pattern of x-ray findings distinguishing it from tendon ossifications or calcifications of other origin.

Achilles Tendon↗
PubMed1980

Pseudo-tumoral ossification of the muscles and/or periosteum. (A study of 57 cases).

The authors present a study of fifty-seven cases of pseudo-tumoral ossification of the muscles ("circumscribed ossifying myositis") and of the periosteum, supported by clinical, radiographic and histological evidence. This pathological condition is characterised by the formation of hyperplastic bone callus in muscle or periosteum, with a typical radiographic appearance, and with a relationship to trauma. We have excluded from our study pseudo-tumoral periosteal ossification in conditions of congenital origin (osteogenesis imperfecta, neurofibromatosis, Sane et al., 1971; Kullman et al., 1972), hyperplastic fracture callus in cranial trauma, ossification of muscles in limbs which are paretic or paralysed due to cerebral or cord lesions, and hyperplastic fracture callus in congenital syphilis. The form which is the subject of this study is absolutely benign, develops over a period of twelve to twenty-four months, with spontaneous maturation and partial regression. It can abe treated by radiotherapy to accelerate maturation, or by surgery when maturation has been completed.

Adolescent↗
PubMed1981

[Genetic study of ossification of the spinal ligaments -hereditary factors for ankylosing hyperostosis (author's transl)].

There has been no report concerning genetic investigation of ankylosing hyperostosis (AH). This is to report the influence of hereditary factor for AH on seventeen probands and fourty-two relatives of sixteen AH families. 1) In the AH families ossifications of the yellow ligament (OYL), posterior longitudinal ligament (OPLL), and supraspinous ligament (OSSL) were more frequently observed roentgenographically in or around the spine, than in the control group. There were 32 cases with OYL, 8 with OPLL and 29 with OSSL among the total of 59 cases. Especially OYL and OSSL were frequently seen even in such younger cases as aged thirties. 2) There were 6 families in which the sibships of probands were able to be examined. Eleven of 15 cases or more than one-half of the sibships were affected by AH in the 6 families. Fourteen out of 15 had some ossifications of the spinal ligament. 3) In this series, Hahn's groove of the vertebral body was observed in 44 out of 59 members. Hahn's groove is presumed to be a causative factor of AH, which we have already reported, and is rarely encountered in normal persons after the age of 20. These results suggest that there exists a genetic diathesis of ossification of the spinal ligaments and a tendency of heredity of ankylosing hyperostosis.

Adult↗
PubMedDate not supplied

Anomalous multifocal ossification of the os calcis.

While accessory ossicles are relatively common in the feet, major developmental chondro-osseous variations in otherwise normal feet appear to be extremely unusual. The "bifid os calcis" has been reported infrequently since its first description by Sever in 1930. The majority of cases are fortuitously diagnosed, usually in children three years of age or older. The current case was diagnosed shortly after birth. The most obvious roentgenographic finding was punctate ossification in the anterior portion. As in other cases, this appeared to be a solitary, bilateral variation of chondro-osseous maturation. Foot development in the fetus includes considerable variation in the development of the calcaneal ossification center and at least two examples of multiple ossification centers.

Calcaneus↗
PubMed1995

IgA nephropathy associated with hyper IgAnemia, psoriasis or pustulosis and ossification.

This is a report on two cases of IgA nephropathy associated with psoriasis vulgaris, having hyper IgAnemia (above 500 mg/dl) and ossification. Case 1 is a 47-year-old woman with a 7-year history of psoriasis vulgaris, and case 2 is a 57-year-old man with a 17-year history of this disease. IgA was 526 and 1,356 mg/dl, respectively. HLA analysis showed A2, A26 (10), Bw62 (15), Bw46, Cw3, DRw12 (5), and DRw8 in the former, and A2, A11, B13, Bw46, Cw11, DR4, and DRw8 in the latter. Renal biopsy specimens disclosed mild mesangial proliferative glomerulonephritis and moderate mesangial proliferative glomerulonephritis with predominant IgA deposition in mesangial area, respectively. A bone-scintigraphy revealed a high uptake of radioisotopes in the left shoulder, the vertebra, the sacroiliac joint, both sides of the knees and ankles, and the sterno-cost-clavicular area. An X-ray study showed ossification of the posterior longitudinal ligament (OPLL) in the former, and ankylosing spinal hyperostosis (ASH) in the latter. A review of the literature discloses three other case reports of hyper IgAnemia, IgA nephropathy, psoriasis or pustulosis, and ossification. The alertness of dermatologists, orthopedic surgeons, rheumatologists, and general practitioners will be required to attain to a more frequent diagnosis of the above combination.

Female↗
PubMed1995

[The radiotherapy of heterotopic ossifications in paraplegics. The preliminary results].

BACKGROUND/AIM: Mobilisation of patients with paraplegia is frequently associated with acute inflammatory processes of soft tissues and muscles in the neighbourhood of joints, where subsequently heterotopic bone formation develops. Rehabilitation is then seriously compromised. For this clinical situation, no local therapeutic options exist so far except extensive resection. To evaluate if radiotherapy early in the course of the disease prevents heterotopic bone formation or if--in case of already manifest ossification and consecutive resection--recurrence can be avoided. PATIENTS AND METHODS: In 20 patients with paralysis, 25 regions were irradiated with (mostly) 10 Gy in single fractions of 2 to 2.5 Gy using 8 MV photons. In 15 patients radiotherapy was performed as a primary treatment in the status of myositis; 7 patients were treated after (subtotal) resection of already manifest ossifications (2 patients were treated twice, primarily and postoperatively). RESULTS: In a minimum follow-up of 12 weeks, none of the 20 irradiated patients showed any progression of the developing or already manifest ossification; thus mobilisation and rehabilitation could be carried out as desired. No side effects occurred. CONCLUSION: The preliminary results of the present study suggest that radiotherapy is an effective local treatment with minimal side effects for the prevention of heterotopic bone formation in patients with paraplegia. Treatment should be started early in the course of the disease. Further evaluation in a prospective study seems desirable.

Adult↗
PubMed1994

Low-dose irradiation and indomethacin prevent heterotopic ossification after acetabular fracture surgery.

From 1987 to 1991, we treated 53 patients with 54 fractures of the acetabulum by reconstruction through a posterior or an extended iliofemoral surgical approach. For prophylaxis against heterotopic ossification we used perioperative irradiation and indomethacin. Indomethacin was given as daily doses of 25 mg started within 24 hours of operation and continued for four weeks. Irradiation was by either 1200 cGy in three daily doses or by a single 700 cGy dose on the first postoperative day. All patients were followed for at least one year postoperatively and the severity of heterotopic ossification was recorded using the Brooker classification and correlated with hip mobility. The combination therapy proved very effective; 44 fractures showed no heterotopic ossification and ten showed Brooker class I. The functional results were good and there were no complications of this therapy. Irradiation with 1200 cGy did not appear to offer any therapeutic advantage over the 700 cGy dose.

Acetabulum↗
PubMed1994

The natural course of myelopathy caused by ossification of the posterior longitudinal ligament in the cervical spine.

The natural course of ossification of the posterior longitudinal ligament, particularly the relationship between the onset of myelopathy and factors associated with its aggravation, was studied in 207 patients during an average period of 10 years 3 months. Myelopathic signs were already present in 37 (18%) patients at the time of the initial examination. Fourteen of these 37 patients showed aggravation of symptoms during the observation period. Myelopathy appeared during the observation period in 33 (16%) of the 207 patients. One hundred thirty-seven (66%) patients were free of myelopathy. Some patients had no myelopathic signs, despite severe spinal stenosis, because of the ossification. In these patients, the range of motion of the cervical spine was severely limited, indicating that dynamic factors are important in the development of myelopathy. In treating this disease, it is necessary to take into consideration the natural course of the disease and to identify the involvement not only of static factors, such as compression caused by ossification, but also of dynamic factors.

Adult↗
PubMed1994

Radiation therapy to prevent heterotopic ossification in cementless total hip arthroplasty.

Heterotopic ossification is the most frequent complication in total hip arthroplasty. In this prospective trial the influence of radiation therapy on heterotopic ossification in cementless total hip arthroplasty was investigated. Radiation therapy reduces the incidence and the degree of heterotopic ossification, especially in hips with a poor preoperative range of motion.

Aged↗
PubMed1994

The significance of sinonasal radiodensities: ossification, calcification, or residual bone?

PURPOSE: To determine whether very radiodense material within a sinonasal soft-tissue mass on CT can be differentiated as calcification, ossification, or residual bone. METHODS: We retrospectively described the radiodensities within 235 sinonasal soft-tissue masses as discrete, solitary or multiple, or as a diffuse process with either a well-defined or poorly defined margin. They were also classified as calcification, ossification, or residual bone. Findings were correlated with pathologic specimens. RESULTS: Residual bone was underdiagnosed; calcification was overdiagnosed. A solitary discrete density was most likely to be calcification within an inflammatory mass. However, multiple discrete densities were as likely to be in a tumor as in an inflammatory lesion. If the process was diffuse with a well-defined margin, it was most likely to be a benign fibroosseous lesion. If the process was diffuse with a poorly defined margin, it was most likely to be a high-grade sarcoma. Densities within inverted papillomas were shown to be residual bone, not calcifications; densities within esthesioneuroblastomas were calcifications. CONCLUSION: Radiodensities may help in refining a CT diagnosis, but one may not know based on CT whether the density is a calcification, ossification, or residual bone.

Calcinosis↗
PubMed1994

[Retrospective study of heterotopic ossification with and without prophylactic indomethacin therapy].

The authors evaluate the problem of heterotopic ossifications as a complication of total endoprostheses of the hip joint. The classification into stages as elaborated by Arcque was used and compared with the clinical correlate. The authors compared the year 1989 when the total number of prostheses was 150 without prophylaxis of ossifications, with the year 1992 when the total number of endoprostheses was 200 with prophylaxis. In 94% of the patients starting on the second day after surgery to the 21st postoperative day 2 x 50 mg Indomethacin (2 x 1 capsule Indocin forte) were administered. As a gastroprotective drug the patients were given Ranitidine, 2 x 150 mg (2 x film tablets Zantac 150). Complications such as gastrointestinal complaints and skin exanthemas were observed only in 6 patients. Prophylaxis of thromboembolic disease was used in 1992 in 65% of the patients by anticoagulants and in 35% of the patients by administration of low-molecular heparin. This procedure proved a very simple, effective and safe method for prevention of para-articular ossifications: [table: see text]

Female↗
PubMed1993

[Ossification and calcification of the cervical ligamentum flavum--case reports].

Ossification of ligamentum flavum was reported usually lower thoracic and lumbar region, and rarely seen in the cervical region. Calcification of cervical ligamentum flavum is also relatively rare. We report a case of ossification and another of calcification of cervical ligamentum flavum, and discussed the difference of the clinical and radiological features in these conditions. Case 1: A 55-year-old man presented with numbness of the left shoulder and urinary dysfunction. Neurological examination revealed weakness, muscle atrophy and elevated deep tendon reflexes of the left extremities. CT showed ossified mass protruding into the right side of the canal and compressing the spinal cord at C 3/4 and C 4/5. MRI showed low intensity mass both on T1- and T2-weighted images and severe compression of the spinal cord. Left side partial hemilaminectomy with foraminotomy, so called "key hole" foraminotomy, satisfactorily decompressed the cord with clinical improvement. Case 2: A 70-year-old woman complained numbness of both hands for two years. She had sensory disturbance of both hands and spastic gait disturbance. Cervical X-ray films showed calcified nodules on the inner surface of lamina at C4/5. Axial CT demonstrated calcification in the ligamentum flavum at the C4/5 and C5/6 levels. MRI showed posterior spinal cord compression at the C4/5 and C5/6 levels. Osteoplastic laminotomy and removal of the affected ligamentum flavum were performed with successful result. Only 8 cases ossification of cervical ligamentum flavum above C6/7 have been so far reported. All are Japanese; four male and four female cases.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1993

The investigations of mechanical properties of ossificating thyroid cartilages of the human larynx.

40 thyroid cartilages were used to investigations, they were taken from bodies of people, died between the ages of 19-99, by the use of the endurance machine with controlled speed of the increase of deformation. It was observed that the durability for flexion and the inflexibility of the investigated cartilages depends on the level of the process of their ossification, that is estimated by the help of the radiological index of the ossification (RIO). On the other hand, the searches of durability forcing of the regions of cartilages that presented different levels of the ossification process, proved the heterogenicity of the structure of the cartilage, in which ossified parts are separated by zones, that did not submit to this process.

Adult↗
PubMed1993

Psoas tenotomy and heterotopic ossification after Charnley low-friction arthroplasty.

One hundred twelve cases of Charnley low-friction arthroplasty (LFA), with elevation of the psoas tendon from the lesser trochanter, were reviewed. Twenty-six (23.3%) had heterotopic ossification in that area. No heterotopic ossification was present in 124 cases without psoas tenotomy. Periosteal elevation at the time of tenotomy is a likely cause of psoas heterotopic ossification.

Adult↗