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At least 667 records · Page 37Linked to original sources
PubMed1999

Isolation of Mucor circinelloides from a case of ulcerative mycosis of platypus (Ornithorhynchus anatinus), and a comparison of the response of Mucor circinelloides and Mucor amphibiorum to different culture temperatures.

The fungus Mucor circinelloides was isolated from a platypus (Ornithorhynchus anatinus) suffering from ulcerative mycosis. On horse blood agar at 20, 25 and 30 degrees C, the fungus formed sphaerule-like bodies, a morphology previously associated with Mucor amphibiorum, the species thought to be responsible for the disease in platypus. A biopsy taken from the ulcer was fixed, cut and stained. The sections were compared with sections taken from other platypuses suffering from ulcerative mycosis, and from which M. amphibiorum had been isolated. There were no discernible differences between the sphaerule-like bodies found in any of the sections. The presence of sphaerule-like bodies in tissues of ulcerated animals can, therefore, probably no longer be relied upon as a definitive method for the diagnosis of M. amphibiorum infection. It is possible that M. circinelloides is either a primary or a secondary pathogen of platypuses, and further work is required to resolve this point. The isolate of M. circinelloides grew at temperatures up to 38 degrees C, with an optimum temperature for growth of 30 degrees C. Of six isolates of M. amphibiorum derived from both platypus and amphibians, two grew well at 38 degrees C. The growth of one of these isolates at elevated temperatures may be explained by the hot climate of the area in Queensland in which it was found. All of the isolates tested had maximum temperatures for growth in excess of the body temperature of platypuses (32 degrees C).

Animal Diseases↗
PubMed1999

[The treatment of vaginal mycosis with Orungal].

UNLABELLED: The authors report their results of the treatment of the vaginal mycosis with Orungal (Janssen-Cilag). Twenty two sexually active women are included in the study, all with clinical signs of fungal vaginitis. Microscopic examination of vaginal secretions and fungal cultures are performed for all of the patients. Twenty cultures show C.albicans as causing agent and 2-non-C.albicans. One-day treatment with Orungal 2 x 200 mg is prescribed. Control examination and mycologic cultures are performed on day 7-10 and 30 after treatment. In 20 patients (91%) there is not clinical signs and the cultures remains negatives. In 2 (9%) the signs of fungal vaginitis persists which evoke the giving of the same dose once again. Adverse reaction (nausea) has been notify by one woman. CONCLUSION: The treatment with Orungal of the vaginal mycosis is highly effective, with minimal adverse reactions and very good acceptance by women.

Adult↗
PubMed2002

[Treatment of the paranasal sinuses mycosis with endoscopic sinus surgery].

OBJECTIVE: To evaluate the treatment effect of endoscopic sinus surgery on the paranasal sinuses mycosis. METHOD: 29 cases of paranasal sinuses mycosis were treated with endoscopic sinus surgery from 1998. The wound was washed with 1% H2O2 and 0.9% NaCl solution after operation. RESULT: In the follow up of 6-36 months, all cases were cured. CONCLUSION: With the endoscopic sinus surgery, the surgeons can get better illumination and the function of nasal cavity and sinuses can be preserved as many as possible. The success rate was high.

Adult↗
PubMedDate not supplied

[Changes in the activity and pattern of hemolymph esterases in the larvae of wax moth Galleria mellonella L. (Lepidoptera, Pyralidae) during mycosis].

The extended pattern of multiple esterase forms has been revealed in the hemolymph of wax moth Galleria mellonella larvae infected by the fungi Metarhizium anisopliae, Beauveria bassiana or Paecilomyces fumoso-roseus. The total esterase activity of the hemolymph also increases during mycosis. Mechanical damage of the cuticle, treatment with deltamethrin, and chilling of the caterpillars induced similar changes in the hemolymph pattern of esterase activity. Presumably, the changed spectrum and activity of the hemolymph esterases during mycosis is due to the damaged cuticle and epidermis cells.

Animals↗
PubMed2006

Guttural pouch mycosis in a 6-month-old filly.

A 6-month-old filly was presented with unilateral epistaxis. Based on clinical signs, endoscopic examination, and postmortem examination, guttural pouch mycosis was diagnosed. The young age of the filly and the fact that this was the 2nd diagnosis of guttural pouch mycosis on this farm was unusual.

Animals↗
PubMed2004

[Some aspects of multifocal and disseminated mycosis].

Some aspects of multifocal and disseminated mycosis are discussed. Special attention is devoted to factors, which play a significant role in the development of fungal infections. Host criteria and microbiological as well as a clinical criteria are discussed. A special attention is given to nosocomial invasions and post-transplantation mycosis.

Adult↗
PubMed1990

Ischemic optic neuropathy and blindness after arterial occlusion for treatment of guttural pouch mycosis in two horses.

Ischemic optic neuropathy accompanied by blindness was induced in 2 horses after surgical occlusion of the external and internal carotid and greater palatine arteries, performed as part of the management of guttural pouch mycosis. The blindness was acute and unilateral and may have been caused by ischemic retinal damage. Vascular occlusion is a recommended procedure for treatment of guttural pouch mycosis. Retinal damage and blindness are a possible complication if all possible sources of hemorrhage are occluded.

Animals↗
PubMed1989

[Clinical efficacy of fluconazole in the patient with pulmonary mycosis].

Fluconazole, a novel triazole antifungal agent, was given orally or intravenously to 10 patients with pulmonary mycosis (7 patients with primary pulmonary cryptococcosis and 3 with pulmonary aspergillosis). Routes of administration were changed in some patients depending on their condition. Two patients from whom foci was removed by surgical operations were excluded from the efficacy assessment. Clinical efficacies in the remaining 8 patients were good in 2 cases and fair in 3 cases of pulmonary cryptococcosis; excellent in 1 case of pneumonia due to Aspergillus; and fair in 1 case and poor in the other case of pulmonary aspergilloma. Side reactions developed in 9 patients who received intravenous drip infusion were nausea or loss of appetite in 3 patients, fever and/or feverish sensation in 3, vascular pain in 1 and diarrhea and eruption in 1. In the patient who reported fever the drug was discontinued and in the patient who complained of pain at the site of injection, dosing was changed to the oral route but was discontinued due to elevated GOT, GPT, Al-P and gamma-GTP. Seven patients who received the drug orally did not report side effects except 2 patients. None of these side effects reported was serious and from the above results, fluconazole was considered to be a useful agent for the treatment of pulmonary mycosis.

Administration, Oral↗
PubMed1989

[A clinical evaluation of fluconazole in the treatment of deep mycosis].

Fluconazole is a novel triazole antifungal agent developed by Pfizer Inc. and available in both oral and intravenous forms. It is characterized by a long serum half-life of 25 to 30 hours and good absorbability into tissues. In the present study, fluconazole was given to 12 patients with deep mycosis orally, intravenously or by local infusion. The patients included 4 cases of candidemia, 1 case each of candidemia and candiduria, candiduria, esophageal candidiasis, Candida hepatic abscess, pulmonary cryptococcosis and septicemia due to unspecified yeasts and 2 cases of pulmonary aspergillosis. Clinical efficacies of fluconazole against these infections were excellent in 2 cases, good in 8 and fair in 2. None of the patients reported any side effects. From the results of the study, fluconazole appears to be a useful and safe drug for the treatment of deep seated mycosis.

Administration, Oral↗
PubMed1989

[Urogenital trichomoniasis and vaginal mycosis in female offenders--a repeat study 20 years later].

The prevalence of urogenital trichomoniasis and vaginal mycosis in 698 female prison inmates in Bratislava was compared with the occurrence of the diseases recorded twenty years ago. The occurrence rate of urogenital trichomoniasis (40.97%) was only slightly reduced compared to the sixties (59.17%), yet it was still five times higher than in the current population. The occurrence rate of vaginal mycosis is much lower in delinquent women (2.3%) than in other women. Trichomonas vaginalis was most frequently present in the age group of 20-29 years (44.67%). All patients with urogenital trichomoniasis were cured with nitroimidazoles. The first treatment was successful in 98.25%, the second treatment with the same dose had a 100% efficacy. Repeated examination of 84 women after two months did not confirm the possibility of intramural infection.

Adolescent↗
PubMed1989

[A study on clinical findings and surgical treatment of pulmonary mycosis].

Between 1974 and 1987, 14 patients (10 male and 4 female) underwent thoracotomy for treatment of pulmonary mycosis. They were studied on their clinical findings and surgical treatment. The median age was 48 years (range 19 to 71 years). Fourteen cases consisted of 9 aspergillosis and 5 cryptococcosis. None of them was either debilitated or immunosuppressed before falling ill. Five of the 14 patients had other pulmonary disease and 11 had symptoms; i.e. hemoptysis or bloody sputum in 4 cases, chest pain in 3, fever in 3, cough and sputum in 2. Nine aspergillosis consisted of 4 aspergilloma, 3 aspergillus pneumonia and 2 aspergillus empyema. Three cases of aspergillosis occurred in preexisting cavity. Five cryptococcosis consisted of 3 pseudotumorous, 1 disseminated small nodular, and 1 infiltrative types. Preoperative diagnosis was as follows; pulmonary mycosis 5, pulmonary tuberculosis 4, lung cancer 3, empyema 1 and hydropneumothorax 1. Four patients underwent partial resection, 8 lobectomy, 1 pneumonectomy, 1 muscle prombage and thoracoplasty. The prognosis is satisfactory. All patients are alive and has no recurrence. On histopathological examination, in aspergilloma cases, invasion of aspergillus to surrounding lung tissue was not seen. In addition to well-known fact that blood-borne dissemination hardly occurred in aspergilloma in contrast to cryptococcosis. These findings suggest that aspergilloma and solitary lesion of cryptococcosis should be resected, and adjuvant chemotherapy should be accompanied for cryptococcosis.

Adult↗
PubMed1989

Mycosis in the stomach compartments of cattle.

During a period of 22 months, 9.7% (23 out of 238) of the cattle necropsied at the Department of Veterinary Pathology had mycotic affections in the stomach compartments. The various stomach compartments were affected in the following pattern: omasum: 15 cases, rumen: 10 cases, reticulum: 8 cases and abomasum: 6 cases. In 5 of the animals mycotic affection was also found in other organs of which the liver was most often involved. Out of the 23 cases described, a primary diagnosis of mycosis was only established in 5 cases. In the remaining 18 cases the mycotic infection was regarded as being of a minor importance in the total necropsy result. Macroscopically and histologically the mycotic processes could be grouped into acute, subacute or chronic affections. In 20 cases only one type of inflammation was present, in the remaining cases combinations were found. Identification of the infective agent was performed by immunological staining of hyphal structures in tissue sections. Members of the Zygomycetes were found to predominate as causative fungi. Aspergillus fumigatus was found to have a propensity for infecting the terminal gastric compartments, whereas the Zygomycetes were found regularly in all compartments. Candida spp. were only found in 1 case. Predisposing factors for developing systemic mycosis are discussed. Among these especially the use of antimicrobial drugs, other diseases, metabolic disturbances and stressors in the post parturient period seem to be important.

Animals↗
PubMed1983

The immunologic and clinicopathologic heterogeneity of cutaneous lymphomas other than mycosis fungoides.

Twenty-one cases of non-Hodgkin's lymphoma with cutaneous involvement, other than mycosis fungoides, were evaluated immunologically, histologically, and clinically. Ten patients presented with skin disease alone, seven with concurrent cutaneous and extracutaneous disease, and four with extracutaneous disease only. Twenty of the 21 cases were nonepidermotropic tumors and were equally likely to express B or T phenotypes. None of the cases expressed a true histiocytic phenotype. Almost all cases expressed la and class 1 HLA determinants. Immunophenotypes were stable regardless of time interval, therapy, or body site sampled in seven of eight patients studied serially. In contrast to mycosis fungoides, the T lymphomas exhibited noncerebriform cytology, tumor la expression, lack of mature helper T-cell phenotype, nonepidermotropic histology, a tendency for marrow involvement, and presented as nodules rather than patches or plaques. Since each T lymphoma expressed an abnormal but uniform T-cell phenotype other than mature cytotoxic/suppressor or helper, the neoplastic population could be distinguished from reactive T cells. Reactive elements averaged one-third of the cellular infiltrates and were mainly T cells and macrophages. Langerhans cells were generally normal in number and distribution. Several histopathologic subtypes were identified with diffuse large cell lymphomas, including immunoblastic lymphomas, comprising 71% of cases (15/21). Prediction of the immunophenotype based on cytologic criteria was correct in 67% of cases (14/21). All errors occurred among the 13 high-grade lymphomas. Survival data were consistent with those of prior studies that have indicated that clinical course is dependent on stage and histologic subtype. Non-Hodgkin's cutaneous lymphomas constitute an immunologically, histologically, and clinically heterogeneous group of neoplasms.

Adolescent↗
PubMed1994

[A clinical study on fluconazole against pulmonary mycosis associated with respiratory diseases].

In 34 hospitals in Kyushu area, the clinical effects and safety of fluconazole (FLCZ) against pulmonary mycosis were studied. To a total of 108 patients with respiratory diseases was FLCZ administered. The results were as follows. 1. Sixty-six cases were evaluable for the clinical efficacy of FLCZ. In 8 cases of pulmonary cryptococcosis, the clinical efficacy rate was 100% (8/8). In 58 cases of pulmonary aspergillosis, it was 43.1% (25/38). Overall, the clinical efficacy rate was 50% (33/66). 2. Fungi were eliminated in 3 of 6 cases in which Cryptococcus was detected, and were eliminated in 8 and reduced in 4 of 30 cases in which Aspergillus spp. including A. fumigatus were detected. 3. Side effects were observed in 5 of 87 cases (5.7%), none of them was serious, however. Abnormal results of laboratory tests that might be related to the FLCZ administration were observed in 5 cases (5.7%). 4. From these results, fluconazole appears to be a potent antifungal agent for treatment of pulmonary mycosis.

Adult↗
PubMed1994

[A clinical study of fluconazole in the treatment of systemic mycosis associated with immunocompromised children].

Efficacies of fluconazole (FLCZ) were evaluated in 8 cases of systemic mycosis (1 case each of candidemia, candiduria, 4 cases of pulmonary candidiasis, and 2 cases of suspected fungemia) complicated in immunocompromised children. Enrolled in the study were 3 patients with acute leukemia, 1 with malignant lymphoma, 2 with congenital immunodeficiency syndrome, 2 with other disorders. The clinical efficacies were good in 6 out of 7 cases. No side effects were observed. FLCZ is a very good and safe agent for the treatment of systemic mycosis complicated with immunocompromised children.

Candidiasis↗
PubMedDate not supplied

Systemic mycosis caused by a new Cladophialophora species.

A 22-year-old woman suffered from haemoptyses of unknown aetiology. A tumour in the lingula was diagnosed histologically to be a granulomatosis, most likely a sarcoidosis. Two years later, the patient returned with dyspnoea caused by a granulomatous tumour in the trachea, histologically similar to that seen earlier. After bronchoscopic laser resection, cortisone therapy was applied but without success. A fungus was subsequently discovered histologically and was cultivated from biopsy specimens. Retrospective research of primary histological slides led to the conclusion that a mycosis was the initial cause of the tumours. The mycosis was successfully treated with high-dose itraconazole for 1 year, combined with 5-fluorocytosine (5-FC) during the first few months. The causative agent was found to be a new species of Cladophialophora, and is described as C. arxii Tintelnot; its key characteristics are presented.

Adult↗