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[Optokinetic reactivity and vestibular disorders of central origin (author's transl)].

An electronystagmographic study of optokinetic reactivity is conducted in 50 'normal' adult subjects and 200 patients suffering from various diseases, all of whom presented an abnormal electronystagmogram. Optokinetic reactivity is evoked by a sudden acceleration of the optokinetic stimulus. It is considered normal when this acceleration leads to an increase in amplitude. At the same time, the frequency of the optokinetic nystagmus decreases. This type of response can be modified by various disorders. Recent cranial trauma and tetany are associated with an incomplete or inadequate optokinetic response; brain vascular diseases and disorders of central origin induce an absence of that response, while some cases of multiple sclerosis and neuro-allergies give rise to an apparently momentary, unstable response. Optokinetic reactivity thus represents an extension of the classical optokinetic test and yields valuable diagnostic clues.

Adult↗

Vestibular syndrome associated with an ependymoma in a cat.

An ependymoma was diagnosed in a 4.5-year-old spayed Siamese cat with clinical signs of vestibular disease. Diagnosis was based on history, results of neurologic examination, and the finding of neoplastic cells in CSF. Necropsy revealed an ependymoma arising from the fourth ventricle of the ventricular CNS and involving the left medullary and cerebellar areas.

Animals↗

Clinical aspects of eye tracking test.

The eye tracking test is today a well established part of clinical otoneurological examination. In the present paper some applications of the test in evaluating of the level of lesion within the vestibular system are reviewed.

Central Nervous System Diseases↗

[Value of the rotation test in acute unilateral vestibular disorders].

The electronystagmographically recorded response of the spontaneous nystagmus and of the per- and postrotatory nystagmus were examined in 70 patients suffering from acute unilateral vestibular disorders. Within a short time the SPN declined logarithmically compared to the reduction of the perrotatory directional preponderance. But the postrotatory nystagmus levels changed only a little in the course of time. The patient's symptoms did not correlate with results of the rotatory test or the intensity of the SPN. The graphs of both parameters (maximal velocity of the slow nystagmus phase and nystagmus frequency in culmination range) which had been analysed showed an almost identical course. Obviously two independent functions are recorded by the caloric and rotatory vestibular test: the rotatory test is said to describe the extent of the central compensation. The lack of conformity in the results of various vestibular tests, including the rotating chair, limit the reliability of the individual tests and indicate that different methods of investigation should always be carried out especially in medico-legal cases.

Acute Disease↗

Abnormalities of the brainstem auditory response of the dog associated with equilibrium deficit and seizure.

The brainstem auditory evoked response (BAER) was recorded from 20 dogs, 10 exhibited vestibular deficit, and 10 presented with a history of seizures. Two dogs exhibited both types of signs. Abnormalities of the BAER, prolonged interwave latency, were seen in 8 of the 10 animals with vestibular problems, and in 7 of the 10 animals with seizure history. Several different diagnosis were associated with BAER abnormalities in both groups of animals. In 55.5% of the cases exhibiting abnormalities of the BAER, postmortem evidence of brainstem pathology was not detected. The electroencephalogram (EEG) was normal in three instances of abnormalities of the BAER. The BAER was normal in three dogs with abnormalities of the EEG. The BAER is presented as a useful diagnostic tool for brain lesions in animals with vestibular deficit and seizure history, but appears most useful when used in conjunction with the EEG. Correlations of abnormalities of the BAER and clinical course of disease are discussed.

Animals↗

[Clinical experiences with the vertical writing test].

The performance of the vertical "X" sign test in 180 patients suffering from peripheral or central lesions was analysed and compared with the findings in 150 healthy persons. Typical features of peripheral diseases were obvious directed deviations in 75.3%. In contrast to this result persons with central lesions showed undirected variant deviations of the vertical X-sign series in 65.6%. This aspect may be helpful in differential diagnosis.

Adult↗