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Perspectives on massive osteolysis. Report of a case and review of the literature.

Massive osteolysis is a rare, chronic disease characterized by the progressive dissolution of contiguous osseous structures. There is no regeneration following the osteolysis. Pathologic fracture often leads to its discovery. The etiology and pathophysiology of the disease remain obscure. Chemo- and radiotherapeutic attempts at arresting the osteolytic process are generally unsuccessful. Bone grafting has proved disappointing, as the graft usually undergoes osteolysis. A new case of facial bone involvement in a 13-year-old boy is presented. The literature is reviewed, and the clinical experience gained from treating the disease is discussed.

Adolescent↗

Early management of civilian gunshot wounds to the face.

We analyzed 54 civilian patients (1988-1992) with gunshot wounds (GSWs) of the face to review the management principles and results. Urgent airway control was needed in 18 cases (33%): by orotracheal intubation in 13, cricothyroidotomy in two, tracheostomy in two, and nasotracheal intubation in one. Central nervous system injury was seen in 12 (22%): 40% with orbital, 38% with mid-face, and 0% with lower face injuries. Two patients died of intracranial injuries (mortality, 4%). Vascular injury was present in five patients (9%), all detected by angiography. The local complication rate was 39% in the presence of intra-oral injury and 0% without intra-oral injury (p < 0.001). The maxilla was the most commonly fractured facial bone (41%) followed by the mandible in 28%. All maxillary, orbital, and zygomatic fractures were treated without reduction. One of the seven nasal fractures required open reduction for deformity. Six of the 15 mandible fractures were treated without reduction. Of eight patients treated with closed reduction, one developed nonunion. One patient treated with immediate open reduction developed osteomyelitis of the mandible and nonunion. Five patients (9%) had palate injuries. Two of them later developed intraoral fistulas following conservative treatment. The airway needs immediate attention in GSWs of the face. Computed tomographic scanning of the head or spine should be done when the bullet trajectory is above the lower face (the level of the mandible). Angiography is indicated when the trajectory of the bullet is suggestive. A conservative approach that effectively reduces the fractures is the procedure of choice. Open reductions should not be performed in the initial treatment.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Alterations in the facial skeleton of the guinea pig following a lesion of the trigeminal motor nucleus.

In thirty-three of sixty-six guinea pigs of the Topeka strain small, unilateral, electrolytic lesions were produced in the motor nucleus of the trigeminal nerve. Unoperated animals and the side contralateral to the muscle paralysis served as controls. Lesions were created when animals were 15 days or 75 days of age, and the animals were killed 15, 30, 45, or 60 days postoperatively. Each animal was subjected to dry skull preparations or radiographic and histologic techniques. Alterations in craniofacial form were noted in both the growing animals and the animals with little growth remaining. Alterations in form and function included paralysis and atrophy of the muscles of mastication on the lesion side, hypereruption of teeth, and reduction in growth of facial bones on the lesion side. Remodeling changes were evident in the glenoid fossa, the condylar process, and the coronoid process on the operated side but were not apparent in the contralateral control or the unoperated control animal.

Animals↗

Reversible visual loss caused by fibrous dysplasia.

Fibrous dysplasia is a developmental anomaly of bone, often affecting the facial bones. We treated a patient who had fibrous dysplasia involving the right maxillary and sphenoid bones. The patient had a sudden loss of visual acuity to R.E.: counting fingers. Visual fields demonstrated a central scotoma, and retrobulbar neuritis was diagnosed. When vision failed to improve spontaneously, however, radiologic studies were performed. These showed compromise of the optic canal by bony proliferation and an apparent mucocele at the orbital apex. Surgical exploration disclosed fibrous dysplastic bone and a cystic structure overlying the optic nerve. Successful surgical excision of the cyst and debulking of the fibrous dysplasia resulted in visual acuity returning to R.E.: 20/25.

Adult↗

Malignant fibrous histiocytoma of the maxilla. Case report and review of the literature.

A case of malignant fibrous histiocytoma (MFH) occurring in the maxilla is presented. Although MFH is now recognised as the most common soft tissue sarcoma of late adult life, it rarely occurs in bone and then more usually in the long bones. Presentation affecting the facial bones and skull is extremely rare, but should be considered in the differential diagnosis of bone tumours affecting the maxilla. Skeletal lesions appear more aggressive than those in soft tissues. Early radical excision is the treatment of choice although radiotherapy for inoperable tumours may lead to regression, as in the case presented here.

Adult↗

Thickness map of parietal bone in Korean adults.

The parietal bone remains the most common donor site for a bone graft in treating facial bone fractures, especially those involving orbital walls. Despite this potential clinical usefulness, anthropometric data on the parietal bone is lacking. Only one Korean and a few foreign studies report on its thickness, measured at two and three points of each of two parietal bones in a given subject, respectively. These studies, however, fall short of offering enough information for locating the optimal harvest point of the parietal bone for bone grafting. This study was thus aimed at constructing a thickness map that provides the mean parietal bone thickness at various points and determines the difference between them. Eighty-eight parietal bones were obtained from 44 Korean adult skulls for this study. Parietal bone thickness was measured at 15 points, spaced at regular intervals on each parietal bone of a given skull, using a Techlock GM 21 caliper gauge. The mean bone thickness at each of the 15 points of the bone and at the corresponding points of the opposite parietal bone was obtained in all skulls studied. The mean thickness at each point of measurement on two opposite parietal bones was compared using the paired Student's t test. Mean thickness did not differ significantly. The thickness in the same bone varied widely depending on the points of measurement. The thickest part, the posteromedial region of the parietal bone near the lambda, was 6.67 +/- 1.41 mm (mean +/- standard deviation [SD]) thick, and it became thinner toward the diagonal (anterolateral) direction, to the thinnest part, 4.73 +/- 1.19 mm (mean +/- SD) thick, near the pterion. It is hoped that our thickness map can serve as a practical guide for choosing an ideal site on the parietal bone for a bone graft of desired thickness.

Adult↗

Aneurysmal bone cyst of the maxilla.

An aneurysmal bone cyst of the maxilla is a nonneoplastic, uncommon, solitary bone lesion recognized by distinct radiographic and histopathological characteristics. It is described as a localized and quickly expandable benign tumor, which can reach a considerable size. It is characterized by the replacement of bone by spongy fibro-osseous tissue and a locally destructive and multicystic lesion filled with blood. It is attributed to a circulatory disturbance leading to locally increased venous pressure but with an unclear etiology. It takes place mainly in the long bones and in patients less than 20 years old, with no sex predilection. Its treatment is by surgical excision. An aneurysmal bone cyst in the facial bone is rare. The present case describes the lesion arising in the maxilla of a 14-year-old girl.

Adolescent↗

Cystic fibrous osteodystrophy of the jaw in two pet kinkajous (Potos flavus).

Two kinkajous (Potos flavus), which were separately owned as pets and fed an inappropriate diet consisting almost exclusively of succulent fruits developed cystic fibrous osteodystrophy of the jaw. In both cases there was a prominent enlargement of the chin and lower jaw, decalcification of facial bones, softening of the gingiva, and severe malocclusion, but no other relevant changes. Clinical, radiographic and histological findings were consistent with cystic fibrous osteodystrophy. The findings suggest that kinkajous with this condition are particularly prone to developing a bulbous enlargement of the chin as the main clinical sign, and that this change is histologically similar to the cystic form of the disease observed in man and monkeys.

Animals↗

Craniofacial chondrosarcomas: imaging findings in 15 untreated cases.

Radiographic findings of 15 untreated chondrosarcomas of the cranial and facial bones were reviewed. These tumors have a propensity to occur in the wall of a maxillary sinus, at the junction of sphenoid and ethmoid sinuses and vomer, and at the undersurface of the sphenoid bone. Because of its slow-growing nature, chondrosarcomas tend to be large, multilobulated, and sharply demarcated when detected. Frequent bone changes are a combination of erosion and destruction, with sharp transitional zones and absent periosteal reaction. Tumor matrix calcifications, not necessarily chondroid, are almost always present. Both CT and MR may be necessary for thorough evaluation of tumor extent.

Adolescent↗