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Chylous reflux into localized pulmonary lymphangiectasis.

Spontaneous chylothorax is uncommon and may originate from different etiologies either pleural, pulmonary, or mediastinal. Chyloptysis is a still rarer clinical problem and always of pulmonary origin. We report 2 cases: the first, a 63-year-old woman presenting with a chylothorax, and the second, a 28-year-old man with chyloptysis. Both were successfully treated with a medium chain triglyceride diet. Lymphangiograms demonstrated an identical origin for the 2 cases: reflux from the thoracic duct into right lower lobe lung lymphangiectasis. In our experience, chylous reflux into pulmonary lymphangiectasis is not as rare as believed and many cases probably remain undiagnosed.

Adult↗

Pleuropulmonary and skeletal lymphangiomatosis with chylothorax and chylopericardium.

Congenital lymphangiomatosis of lung and bone, with or without chylothorax, is a rare but often fatal systemic lymphatic malformation. In those who survive infancy and early childhood, parietal pleurectomy with excision of lymphatic lakes and ligation of the thoracic duct can be successful. Two patients with lymphangiomatosis are described, 1 with chylothorax and chylopericardium with generalized skeletal lesions and the other with pleuropulmonary lesions and chylothorax. Both were successfully treated with parietal pleurectomy, excision of lymphatic lakes, and ligation of lymphatics, including the thoracic duct. To our knowledge, the triad of generalized skeletal lymphangiomatosis, chylopericardium, and chylothorax has not been previously reported.

Adolescent↗

The management of chylothorax.

A series of 15 patients was treated for chylothorax over a 20-year period. The anatomy, physiology, and diseases of the thoracic duct are described, and a plan for the management of chylothorax is presented. If conservative therapy (e.g., aspiration or drainage with restriction of oral intake and intravenous replacement) is not successful after two to three weeks, surgical treatment is necessary and efficacious. The thoracic duct is explored by a full thoracotomy on the side of the effusion. It is readily seen if 6 to 8 oz of a mixture of milk and cream is given to the patient a few hours before operation. The milky fluid drips from the open duct, which is easily oversewn.

Adult↗

The pericardium.

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Cardiac Tamponade↗

Case report: investigation of chyluria.

We present a case of chyluria in which the demonstration of abnormal lymphaticourinary communication was established by conventional lymphangiography. Radiocolloid lymphoscintigraphy failed to demonstrate the site of leakage, probably due to technical factors which are discussed.

Chyle↗

Chyluria.

Thirty cases of chyluria seen in Rangoon during the years 1968-1973 have been investigated. Blood micro-filaria was positive in only a small number of cases. Renal function was not disturbed and blood eosinophil count was normal. The duration of symptoms varied from 3 months to 10 years. Males and females were equally affected and the disease was much more commonly seen in the 20 and 40 age group. Retrograde pyelography demonstrated pyelolymphatic reflux. Lymphangiograms showed numerous lymphatics in the region of the calves and contrast was often seen in the calyceal system. The thoracic duct was patent in all the cases. Renal lymphatics were opacified in three patients who were investigated by intravenous urography. Para-renal cysts, pressure on the renal pelvis by an enlarged lymph node and dilated lymphatic vessels were associated features.

Adolescent↗

Chylous effusions due to neuroblastoma resolved by intrapleural chlorambucil coupled to father's antibodies.

A 2-year-old boy presented with a stage IV neuroblastoma and, despite surgical reduction of the tumor mass followed by chemotherapy and radiotherapy, he developed bilateral chylous pleural effusions. These proved resistant to traditional methods of treatment but were resolved with minimal discomfort to the child by intrapleural injections of chlorambucil chemically bound to antibodies raised by immunizing his father with irradiated tumor cells.

Antibodies, Neoplasm↗

Bilateral excision of perinephric fat and fascia (Gerota's fasciectomy) in the treatment of intractable chyluria.

A case is described of a 59-year-old black man with massive chyluria, probably due to previous infection with Wuchereria bancrofti. Notably, no edema was present despite a urinary protein loss of 40 gm. per day resulting in a serum albumin level of 13 gm./l. Conservative treatment after lymphography, including prolonged bedrest and a medium chain triglyceride diet, was unsuccessful. Bilateral excision of the perinephric fascia and fat (Gerota's fasciectomy) in 2 separate operative sessions finally resulted in complete resolution of the chyluria.

Adipose Tissue↗

Microsurgical treatment of chyluria: a preliminary report.

We treated 80 patients with recurrent chyluria (68 men and 12 women) by a microsurgical technique since 1978. Transinguinal spermatic lymphangiovenous anastomosis was performed in 64 patients and inguinal lymph node-saphenous vein anastomosis was performed in 16. Followup was 6 months to 11 years in 50 of the former and 12 of the latter patients. Chyluria disappeared completely in 30 (60%) and 8 (66.7%) patients, respectively. In 6 of the former patients (12%) chyluria had disappeared immediately after the operation but it recurred within 1.5 to 3 years. The procedure has the advantage of a superficial operative field, and is simple and less traumatic.

Anastomosis, Surgical↗

Experiences in the treatment of chyluria in Taiwan.

From 1967 through 1986, 55 patients with chyluria were treated by renal pelvic instillation of 10 ml. 0.5% silver nitrate solution and surgical disconnection of the renal pedicle lymphatics was done in 9 (16.3%) due to persistent chyluria after instillation therapy. Among these 46 renal pelvic instillation patients and 9 operated patients followed for 2 years chyluria recurred in 11 (22.7%) and 5 (55.5%), respectively. Renal pelvic instillation is a safe and effective method to treat chyluria.

Chyle↗