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Is anterior chamber lens implantation after intracapsular cataract extraction safe in rural black patients in Africa? A pilot study in KwaZulu-Natal, South Africa.

PURPOSE: There are an estimated 16 million people blind from cataract world-wide. In many areas the routine operation is intracapsular cataract extraction (ICCE). The role of modern anterior chamber (AC) intraocular lenses (IOLs) is being explored, and they have been shown to be safe and successful in Asia. Are they equally safe in rural black African populations? METHODS: One hundred black patients aged 50 years and over who attended Edendale Hospital were enrolled in a pilot study of insertion of AC IOLs after ICCE. They were followed up for 6 months. RESULTS: With financial remuneration, the follow-up rate at 8 weeks increased from the usual 30% to 72%. At 6 months, 67% of eyes achieved a correlated visual acuity of 6/18 or better. Thirty per cent had persistent uveitis, 16% had peripheral anterior synechiae beyond the points of haptic contact, and 5% had an intraocular pressure greater than 21 mmHg. CONCLUSIONS: A randomised trial comparing ICCE with AC IOL and extracapsular cataract extraction with posterior chamber IOL is probably not justified at this time in this population. However, there may be wide variations in the reaction of the eyes of different African ethnic groups to IOLs. In view of the successful use of AC IOLs in Asian eyes, further pilot studies of AC IOLs may be warranted in other parts of Africa where ICCE is the routine procedure.

Black or African American↗

[Cataract extraction including posterior chamber lens implantation in the treatment of acute glaucoma].

OBJECTIVE: The aim of this study was to compare phacoemulsification in eyes with angle-closure glaucoma to the partner eyes with or without iridectomy or laser iridotomy, respectively. METHODS: Twelve eyes with an elevated intraocular pressure due to an angle closure that were treated by phacoemulsification and IOL implantation were compared with 12 partner eyes with narrow angle and iridectomy or iridotomy without intraocular pressure elevation and cataract extraction. The average follow-up period was 15.7+/-2.1 months. RESULTS: The average intraocular pressure in eyes with angle-closure glaucoma was 54.1+/-14.7 mmHg and in the partner eyes 22.4+/-8.6 mmHg preoperatively. Follow-up pressure was 19.3+/-2.0 mmHg in eyes with angle-closure glaucoma and 18.8+/-1.5 mmHg in the partner eyes. CONCLUSION: Primary cataract extraction including posterior chamber lens implantation into eyes with angle-closure glaucoma reduced intraocular pressure to normal levels, increased visual acuity, and decreased the number of antiglaucomatous drugs. Eyes with angle-closure glaucoma do not respond differently to phacoemulsification and lens implantation compared to eyes with narrow angle without pressure elevation during and after phacoemulsification.

Aged↗

Comparative study of intraocular pressure change after cataract surgery: phacoemulsification and extracapsular cataract extraction.

A randomized prospective study was performed to evaluate intraocular pressure (IOP) change after extracapsular cataract extraction (ECCE) or phacoemulsification and aspiration (PEA) with implantation of posterior chamber intraocular lens in otherwise normal cataract patients. IOP was measured preoperatively and postoperatively at up to 6 months. There was a mean fall in pressure of 1.1mmHg (5.72%) in the ECCE group (15 eyes) and of 0.6mmHg (4.16%) in the PEA group (24 eyes) after 6 months. The decrease in mean IOP was significant at 2 months in the PEA group and at 4 to 6 months in the ECCE group, but there was no statistically significant difference between the two groups during the follow-up periods (p < 0.05). The present study shows that there was some postoperative IOP reduction in both the ECCE and PEA group, but the amount of reduction was not significantly different between the two groups.

Aged↗

Intraocular pressure control and visual outcome in patients with phacolytic glaucoma managed by extracapsular cataract extraction with or without posterior chamber intraocular lens implantation.

BACKGROUND AND OBJECTIVE: To evaluate long-term intraocular pressure (IOP) control and visual outcome of patients with phacolytic glaucoma. PATIENTS AND METHODS: Forty-five consecutive eyes of 45 patients with phacolytic glaucoma operated on between January 1990 and December 1995 and who had completed at least 1 year of follow-up were included in the study. Of the 45 eyes, 17 eyes underwent extracapsular cataract extraction (ECCE) with primary posterior chamber intraocular lens (PC IOL) implantation (group 1). The rest of the eyes (n = 28) underwent only ECCE (group 2) in view of satisfactory aphakic vision in the contralateral eye. Preoperative IOP, visual acuity, and anterior segment appearance were compared with postoperative data. RESULTS: IOP was controlled (IOP < 21 mm Hg) in all of the patients without any antiglaucoma medication, with a mean follow-up of 29.11 +/- 16.25 months (range 12 to 60) and 43.2 +/- 21.5 (12 to 78) months in groups 1 and 2, respectively. The IOP remained controlled without antiglaucoma medication even in the patients where the desired visual recovery was not obtained due to glaucomatous disc damage because of delayed presentation (2 to 3 weeks or more). A visual acuity of 20/40 or better was achieved in 76.5% and 60.7% in groups 1 and 2, respectively. Eighteen of the 45 patients initially presented with light perception without projection. Eight of these 18 patients (44%) regained a visual acuity of 20/40 or better. There was no significant intraoperative and postoperative complication in any patient. CONCLUSIONS: ECCE with or without primary PC IOL implantation is safe and curative in patients with phacolytic glaucoma. The addition of trabeculectomy to cataract extraction seems to be superfluous in the control of IOP in patients with phacolytic glaucoma operated on within 2 to 3 weeks of the onset of symptoms. Light perception without projection is not a contraindication for cataract surgery in phacolytic glaucoma.

Aged↗

Propionibacterium acnes endophthalmitis with bacterial sequestration in a Molteno's implant after cataract extraction.

PURPOSE: To report a case of Propionibacterium acnes endophthalmitis following uncomplicated cataract extraction with bacterial sequestration in a preexisting Molteno's drainage implant. DESIGN: Interventional case report. METHODS: A 7-year-old girl with congenital glaucoma and a preexisting Molteno's drainage implant developed anterior nongranulomatous uveitis 4 months following cataract surgery. P. acnes endophthalmitis was diagnosed by polymerase chain reaction, Southern blot, and electron microscopy. RESULTS: Extraction of the Molteno's implant was required to control the persistent intraocular inflammation and to convert the results of polymerase chain reaction and Southern blot testing of aqueous sample for P. acnes from positive to negative. CONCLUSION: P. acnes may be sequestered in glaucoma implants, potentially requiring implant removal to treat cases of P. acnes endophthalmitis.

Aqueous Humor↗

Cataract extraction in a fur seal.

Cataracts are common in pinnipeds, but ocular examination and surgery are complicated because of the small pupil, which is difficult to dilate with mydriatics. Vision was evident after a cataract was removed from a fur seal, using a manual technique of irrigation and aspiration. Access to the lens was limited by the constricted pupil, which could not be dilated with tropicamide, phenylephrine, or atropine.

Animals↗

Intraocular pressure seven years after extracapsular cataract extraction and sulcus implantation of a posterior chamber intraocular lens.

Seven years after extracapsular cataract extraction (ECCE) and sulcus implantation of a posterior chamber intraocular lens, we measured the intraocular pressure (IOP) in 28 eyes of 28 patients. The results were compared with the preoperative IOP and with the postoperative IOP at four months and 2 1/2 years. The mean IOP value seven years after surgery was 1.3 mm Hg lower than the preoperative mean value. No significant difference was found among the values at four months, 2 1/2 years, and seven years. One patient experienced a marked rise in IOP between 2 1/2 years and seven years and was excluded from the calculations. However, we could not tell whether it was a consequence of the cataract surgery. In this study, we found that IOP stabilized at a postoperative level that was significantly lower than the preoperative value and has remained there for seven years.

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