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Results for “ANTISEPTICS”

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At least 667 records · Page 37Linked to original sources
PubMed1986

Susceptibility of porin- and lipopolysaccharide-deficient strains of Escherichia coli to some antiseptics and disinfectants.

The sensitivities of some outer membrane protein (Omp) and/or lipopolysaccharide (LPS)-defective mutants of Escherichia coli to chlorhexidine and some quaternary ammonium compounds (QACs) were examined. Wild-type strains, with no defect in Omp or LPS were the most resistant to QACs, whereas LPS-deficient strains were the most sensitive. As expected, QAC resistance could not be related to the presence or absence of any specific porin(s). Chlorhexidine was highly active against all strains, inhibitory concentrations lying within the narrow range of 1 and 2 mg l-1.

Anti-Bacterial Agents↗
PubMed1987

The effect of antibiotic prophylaxis and topical antiseptics on the bacterial flora of the skin after cardiac surgery.

A controlled trial of antibiotic prophylaxis in cardiac surgery compared a two-dose regimen of teicoplanin with a longer conventional course of flucloxacillin and tobramycin. In 12 patients the susceptibility of the bacterial skin flora of four different sites to each of the three antibiotics was determined and the results are reported here. Less than 1% of the Gram-positive colonies showed reduced sensitivity to teicoplanin (MIC greater than or equal to 4 mg l-1). Before operation, 99% inhibition of Gram-positive growth was achieved at 26 (54%) of 48 sites by 1 mg l-1 of flucloxacillin and 13 (27%) sites by 2 mg l-1 tobramycin. By the 7th day after operation there was a significant reduction in the number of sites showing similar sensitivity to flucloxacillin [16 (33%) sites, P less than 0.05]. The use of teicoplanin was not associated with the emergence of Gram-negative skin flora but tobramycin promoted acquisition of aminoglycoside-resistant strains.

Adult↗
PubMed1988

How cost-effective is the present use of antiseptics?

There are no studies about cost-effectiveness of hand hygiene in the literature. Instead of doing studies about cost-effectiveness, investigations on how to convince doctors and nurses that hand hygiene is absolutely necessary, should be performed. Disinfection by physical methods is more cost-effective than disinfection by chemicals.

Anti-Infective Agents, Local↗
PubMed1986

Evaluation of a new antiseptic dressing in minor burns.

A prospective trial was conducted to compare a new povidone iodine impregnated dressing (Inadine) with a standard petroleum jelly gauze dressing for small superficial burns treated on an outpatient basis. The results show no difference between comfort and ease of removal of dressings, in the number of positive bacteriological cultures or the number of days to healing. Inadine is more than twice as expensive as petroleum jelly gauze.

Adolescent↗