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At least 667 records · Page 37Linked to original sources
PubMed1984

Rod-cone interaction in flicker detection.

There is considerable evidence in the literature that rod-cone interaction occurs when both rods and cones simultaneously detect a test target. More recent evidence, however, has shown a parafoveal rod-cone interaction during dark adaptation for a purely cone-detected flickering test stimulus; this influence on cone threshold appears to be mediated by surrounding rods. In this study, we demonstrate a similar rod-mediated influence on parafoveal cone-detected flicker threshold. More surprisingly, foveal cone-detected thresholds are also influenced by rods. This effect occurs over at least a 2 log unit intensity range of mesopic background level; cone-detected 25 Hz flicker sensitivity is enhanced by increasing the radiance of the background. The action spectrum of this effect fits the scotopic spectral sensitivity curve. At higher background levels, this rod-cone interaction disappears and surrounding cone activity then influences the cone flicker threshold. The results suggest that, as rods recover sensitivity, they reduce cone-detected flicker sensitivity, even at the fovea. The rod influence on cone flicker is most apparent for long wavelength test stimuli. Our results, in agreement with recent reports, suggest that the rod-cone interaction is laterally-mediated and may be specific for the long wavelength-sensitive cone type.

Adaptation, Ocular↗
PubMed1985

Determinants of the spatial properties of cone-rod interaction.

Photopic increment thresholds can be elevated by 0.2-1.9 log units, depending on the diameter of a concentric scotopic background. This cone-rod interaction displays spatial properties that resemble the spatial sensitization (Westheimer effect) observed in the isolated scotopic and photopic systems. This raises the possibility that the spatial properties of the interaction are determined by the same mechanisms or pathways that determine the spatial properties of either scotopic or photopic vision. When annulus backgrounds are used, the spatial properties of interaction match those of the scotopic system but not the photopic system. When disk backgrounds are used, the spatial properties of interaction match those of neither photopic nor scotopic systems. Thus, under some conditions, the scotopic visual system alone is sufficient to determine the spatial properties of cone-rod interaction. Under other conditions, additional complications arise. The results are discussed in terms of the center-surround model that has previously been applied to cone-rod interaction.

Adaptation, Ocular↗
PubMed1986

Interocular sensitization to a rod-detected test.

Intense red light adaptation of one eye lowers the dark adapted ("absolute") threshold of a 661 nm, extrafoveal, 1.02 deg test flash in the other eye, by about 0.15 log units, for 10-15 min. This effect ("interocular sensitization") also occurs with an extrafoveal 491 nm test, but does not occur if the 661 nm test is foveal, or is made small and brief. Blue or green light adaptations, matched either photopically or scotopically to the red, do not produce interocular sensitization. Thus the conditions producing the effect include intense red light adaptation of one eye, and scotopically mediated detection in the other.

Adaptation, Ocular↗
PubMed1986

The influence of cone adaptation upon rod mediated flicker.

The influence of annular fields on sensitivity to sinusoidal flicker was assessed in the dark adapted parafoveal retina. Test stimuli were 2 degrees 20' in diameter; annuli had a 2 degrees 20' inner and 7 degrees 30' outer diameter. Rod flicker was studied with a "green" stimulus too dim to influence cones. Selective cone flicker was obtained using red and green flicker in counterphase and yoked together in modulation depth and scotopic illuminance. Results showed the following. (1) Annular stimulation of rods slightly facilitated rod-mediated flicker sensitivity to frequencies less than 10 Hz. In contrast, annular stimulation of cones greatly facilitated rod-mediated sensitivity, particularly for flicker frequencies greater than 7 Hz. We designate this effect, cone-rod interaction. (2) Annular stimulation of cones has a negligible influence upon sensitivity to cone-mediated flicker frequencies less than 15 Hz. In contrast, annular stimulation of rods has a large influence upon sensitivity to cone-mediated flicker, an effect we designate rod-cone interaction. (3) Within limits, both rod-cone and cone-rod interaction increase as the annular illuminance increases and as flicker frequency increases; the limiting frequency and illuminance values, however, are different for the two forms of interaction. Results are compared with prior evidence that rod and cone signals summate to produce an absolute threshold or flicker sensation. We suggest that there are at least three mechanisms for interaction between rod- and cone-related signals.

Adaptation, Ocular↗
PubMed1987

The time-course of multiplicative and subtractive adaptation process.

This paper examines, for foveal cone vision, the processes which mediate the transition to a steady state of adaptation following a change of illumination. In the steady state, the signal from an adapting field is attenuated not only by a multiplicative factor (reduction in gain) but also by a subtractive signal. We show that the multiplicative change is accomplished very rapidly following the onset of an adapting field (within about 50 msec). Much of the subtractive change is also accomplished rapidly, but it takes several sec to complete. At the offset of the field, the multiplicative process takes over 200 msec to recover. This slower time-course at offset may be a consequence of receptoral persistence.

Adaptation, Ocular↗
PubMed1990

The spread of adaptation in human foveal and parafoveal cone vision.

We investigated the spread of bleaching adaptation for human cone vision in the central fovea and at an eccentricity of 5 deg in the nasal retina. Cone thresholds measured after adaptation to a grating bleach were compared to those measured after a uniform bleach. We conclude that the foveal and parafoveal cone systems show excellent localization of the effects of adaptation. For areas 2.5-5 min removed from the bleach, our measurement show only small sensitivity losses amounting to between 0.10 and 0.25 log unit elevation in threshold, after taking account of optical scatter.

Adaptation, Ocular↗
PubMed1992

Rapid and slow changes in the human cone electroretinogram during light and dark adaptation.

Changes in the response characteristics of the human cone electroretinogram (ERG) during light and dark adaptation were studied in two visually normal subjects. Cone ERG responses were isolated under all adaptation conditions through the use of 31 Hz flicker. To determine the time-course of changes in the cone ERG during adaptation, responses to stimuli of constant luminance were measured repeatedly during 15 min of exposure to an adapting field of 2.0 log cd/m2 and during 30 min of dark adaptation following adapting field termination. In addition, luminance-response functions were obtained before and immediately after adapting field onset, as well as before and immediately after adapting field termination. The results indicate that the human cone ERG is influenced by two major processes. One process has a relatively rapid time-course and serves to reposition the luminance-response function along the luminance axis following changes in ambient light levels. The second process, which has a slow time-course, scales response amplitudes during light and dark adaptation by the same proportion at all stimulus luminances. The results provide a framework for predicting the manner in which the cone ERG will change with alterations in the state of retinal adaptation.

Adaptation, Ocular↗
PubMed1992

Subtractive processes in light adaptation.

We measured the time course of light adaptation in foveal vision following the onset of an adapting background. Several adaptational steps in the low to mid photopic range were examined. The time course of multiplicative and subtractive components of the adaptation were extracted from the data. Unlike previous findings there were no subtractive changes for several hundred milliseconds following light onset, and the process took 10-15 sec to reach steady state. It seems likely that the fast component previously observed results from effectively instantaneous center-surround antagonism, and that our measurements reflect a second subtractive process involving the slow loss of the d.c. signal over time.

Adaptation, Ocular↗