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PubMed1979

Bilateral Meniere's disease.

A survey of 265 Japanese patients with Meniere's disease revealed bilateral involvement in approximately 29% of all these patients. Somatic and psychiatric aspects of bilateral Meniere's disease were as follows. (1) The duration of the disease in cases of bilateral involvement was significantly longer than cases of unilateral involvement. (2) An abnormal general condition, a more extensive degree of hearing loss and neurotic type were frequently diagnosed in cases of bilateral involvement. Based on these results, it was concluded that psychiatric management and prevention of aggravation of deafness should be part of the management of treatment in bilateral Meniere's disease.

Female↗
PubMed1979

Vestibular neuronal function during ischemia. Response of vestibular neurons to vertebral and carotid artery occlusion in rabbits.

The relation between ischemia experimentally produced by occlusion of arteries injecting to the brain and the changes in vestibular excitability was examined in 102 rabbit vestibular neurons responding to sinusoidal rotation. During occlusion of ipsilateral and/or contralateral vertebral and common carotid arteries, the neuronal activity took on three different patterns with respect to the frequency of neuronal discharge. The incidence of alteration of neuronal activities reflected vestibular excitability dependent on hemodynamic changes due to occlusion of the ipsilateral vertebral artery rather than due to occlusion of the contralateral artery. Occlusion of common carotid arteries caused no significant difference between the right and left vessels in the resultant change of the neuronal activity, and differed little, either, from occlusion of vertebral arteries in the incidence of the changes. A supplementary experiment, in which the four arteries were only partially occluded, clearly showed that the resultant changes in neuronal activity reflect the role of Willis' circle in the maintenance of blood flow to vestibular nuclei.

Animals↗