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At least 649 records · Page 36Linked to original sources
PubMed1985

Double-pointed 30-gauge needle for keratocentesis.

A new, efficient instrument for performing keratocentesis for aqueous humour aspiration and anterior chamber microinfusion is described. It consists of a double-pointed 30-gauge needle, a liquid container (a nonflexible vinyl tube plugged at one end with a rubber stopper) and a aspiration-infusion syringe connected to the container and needle by a flexible vinyl tube. The instrument's advantages are a safer technique, complete collection of the aqueous humour and better handling of the sample.

Aqueous Humor↗
PubMed2003

[Hygienic requirements for biopsy and autopsy diagnostics].

In former times autopsies were the main task of a pathologist and therefore the most frequent source of infection but nowadays cytological and biopsy investigations dominate the pathologist's work. Usually the time interval between the extraction of a specimen, its transport into the laboratory and return of the report is no longer than a few hours. Consequently the staff must often handle unfixed or insufficiently fixed material. This and the occurrence of new infectious diseases, e.g. AIDS and TSE (transmissible spongiform encephalopathies), makes it necessary to analyse and perhaps even change the work in respect to hygiene risks and demands for permanent protection against infection. First of all the risks of infection and the common measures of protection from infections for the staff in biopsy and autopsy departments will be described. Subsequently suggestions to reduce infectious risks in special activities will be presented. The examination of frozen sections or intraoperative biopsy material and the handling of specimens possibly contaminated by HIV and TSE will be considered separately.

Autopsy↗
PubMed1977

A method to facilitate the isolation and handling of stratum corneum.

A specially designed frame is being used in this laboratory to facilitate the isolation and handling of human cadaveric stratum corneum of the upper back. Although it is in the early stages of use, the ease of isolation and subsequent handling of the stratum corneum has prompted the writing of this short report.

Skin↗
PubMed2002

Frozen sections in hematopathology.

The diagnostic complexity of lymphoproliferative disorders has increased tremendously within the last decade as evidenced by the recently published World Health Organization (WHO) classification of hematological malignancies. Diagnosis of these malignancies now often requires confirmation by ancillary studies, such as immunohistochemistry, flow cytometry, cytogenetics, and/or molecular studies. In fact, in some cases, these ancillary studies are diagnostic rather than simply confirmatory; furthermore, results from these studies may play a direct role in selecting patient therapy. Importantly, this comprehensive approach to the diagnosis of hematological disorders starts at the time of receipt of fresh tissue in the anatomic pathology laboratory. Appropriate handling and triaging of this fresh tissue, which includes recognizing grossly abnormal areas, interpreting the frozen section, and deciding to send portions of the specimen to ancillary laboratories, is pivotal to the optimal diagnosis, prognostication, and ultimate management of the patient.

Frozen Sections↗
PubMed1982

Practical methods for biological NMR sample handling.

The ability of NMR parameters T1 and T2 to be used to distinguish one tissue from another and diseased from normal tissues has wide application in diagnostic medicine. Measurement of such values in vitro on excised tissues and fluids was the basis for fundamental discoveries which provided the impetus for the development of in vivo clinical whole body NMR imagers. Therefore, as in vivo imaging grows, the need for screening and testing of new ideas in vitro will grow. The success of data collection in vitro depends greatly on the care and understanding with which biological samples are processed. This paper summarizes proven methods for handling of soft and firm biopsy material, blood components, body fluids, and culture cells. The effects of temperature variation and storage parameters are discussed for animal and human samples. The paper is a practical guide to the hows and whys of biological sample handling for NMR.

Animals↗