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The routine or screening obstetrical ultrasound examination.

The debate concerning the value of routine screening ultrasound in the low-risk patient continues. The most likely benefits are obstetrical, with confirmation of dates, detection of multiple gestation, baseline growth data, and location of the placenta being primary advantages gained from such an examination. The detection of the unexpected major fetal malformation has always been the least likely benefit of routine ultrasound. Furthermore, the majority of reports have been retrospective, uncontrolled, and too small to resolve the question. The RADIUS study was intended to solve these problems, but suffered from such intense selection that the final population for study had little need for medical care at all and little relevance to the average population. The rate of adverse outcomes among the control group was so low that few interventions would appear useful. Furthermore, the analysis of the RADIUS data appeared to suggest bias by underestimating the diagnostic sensitivity of ultrasound for major anomalies, and de-emphasizing those statistically significant obstetrical benefits that were recorded. An attempt at cost-benefit analysis by the RADIUS study misrepresented the cost of routine ultrasound by overestimating the size of the low-risk population, arbitrarily costing out two scans instead of one, and therefore overestimated the cost savings of omitting these examinations. Diagnostic sensitivity of the screening obstetrical ultrasound examination appears to be highest in high-risk patients examined by highly specialized ad experienced personnel that may be of limited availability. diagnostic sensitivity may be quite good, however, even in low-risk patients with a basic or routine examination if recognized guidelines for content are followed and referral to experienced referral resources for unclear or suspicious images is liberally practiced. Optimal service and minimum liability exposure will result if the following guidelines are followed: 1. The obstetric population should be carefully screened for historical or clinical risk factors that might indicate increased probability of fetal abnormality. Identification of such increased risk should cause consideration of referral. 2. The screening ultrasound examination should be methodical and complete and include examination of each of several recommended scanplane views to maximize diagnostic sensitivity. 3. The performance of a complete and methodical examination should be carefully documented with both descriptive text and image records to show that a standard of care service was provided. 4. Referral for second opinion should be easily considered and easily obtained in the case of any suspicious finding. Should every obstetrical patient have an ultrasound examination? Only if it is competently performed, properly recorded, and if the patient is aware of appropriate goals and limitations. The ideal gestational age is between 18 and 22 completed weeks.

Congenital Abnormalities↗

Domestic violence in the pregnant patient: obstetric and behavioral interventions.

Every day, obstetric providers treat patients experiencing domestic violence. Domestic violence can have both dramatic and subtle impacts on maternal and fetal morbidity and mortality. This article enumerates patient risk factors for and obstetric consequences of domestic violence. It describes adaptations to the assessment and treatment of pregnancy complications occurring in the context of domestic violence and presents behavioral interventions that can be performed within existing obstetric care delivery systems. Behavioral interventions include assessments of a patient's readiness for change and her emotional responses to the violence. Obstetric interventions include an assessment of risk of physical harm to a pregnant woman and her fetus from domestic violence. Interviewing techniques include educating the patient about the effects of abuse and, over time, validating a patient's efforts to change. Reliance on a team approach and use of community resources are emphasized. All of these mechanisms enable obstetric providers to assist pregnant women in taking steps to end the abuse.

Battered Women↗

Gynaecological and obstetric disorders in coeliac disease: frequent clinical onset during pregnancy or the puerperium.

BACKGROUND AND AIM: While gynaecological and obstetric disorders have been reported among women with coeliac sprue, their true prevalence and relationship to the coeliac disease process has not been completely elucidated. Our aims were to determine: (1) the prevalence of gynaecological and obstetric problems in patients with coeliac disease and the influence of strict gluten restriction on their occurrence, (2) the effect of pregnancy on the clinical course of coeliac disease and (3) the clinical features of those patients with onset of coeliac disease during pregnancy and the puerperium. PATIENTS AND METHODS: The gynaecological and obstetric history of 130 coeliac patients and 130 age-matched healthy female controls were compared in a case-control study. RESULTS: In comparison to the controls, untreated coeliac disease patients exhibited significantly later menarche, an earlier menopause, an increased prevalence of secondary amenorrhoea and a greater incidence of spontaneous abortions. Patients who had adhered, in the long term, to a gluten-free diet had gynaecological and obstetric history indistinguishable from controls. Clinical deterioration of coeliac disease was observed in untreated patients during 17% of their pregnancies. In 14% of those untreated patients who were pregnant symptoms related to coeliac disease were manifested for the first time during either pregnancy (n = 7) or the puerperium (n = 4). Nine of these patients had underestimated features suggestive of coeliac disease. CONCLUSION: The early diagnosis and treatment of coeliac disease may avoid significant gynaecological and obstetric complications in affected women. Celiac sprue must always be borne in mind among patients who develop diarrhoea and weight loss during pregnancy and/or the puerperium.

Abortion, Spontaneous↗

Obstetric outcome in women with subfertility.

BACKGROUND: It has been suggested that a history of subfertility is associated with increased obstetric and perinatal risks. It is unclear if the cause is inherent characteristics in the women or the fertility treatment. OBJECTIVES: To compare the obstetric and perinatal risks of singleton pregnancies in women with a history of subfertility in comparison with the general population. DESIGN: Population cohort. SETTING: Aberdeen, Scotland. POPULATION: Cases were women attending the Fertility Clinic between 1989 and 1999 who subsequently went on to have singleton pregnancies. Controls included the general population of women who delivered singletons over the same period. METHODS: We performed a retrospective cohort study to investigate the obstetric outcome of singleton pregnancies in women with subfertility. The general population of women who delivered singletons over the same period served as controls. MAIN OUTCOME MEASURES: Obstetric and perinatal complications in singleton pregnancies. RESULTS: Maternity records were available for a total of 1437 subfertile women and 21,688 controls. Subfertile women were older [mean (SD) age: 31 (4.7) years vs 27 (5.4) years, P < 0.01] and more likely to be primiparous (70% vs 65%, P < 0.001). After adjusting for age and parity, subfertile women were at increased risk of pre-eclampsia (OR 1.9, 95% CI 1.5-2.5), placenta praevia (OR 3.9, 95% CI 2.2-7.0) and placental abruption (OR 1.8, 95% CI 1.1-3.0), and more likely to undergo induction of labour (OR 1.5, 95% CI 1.3-1.6), caesarean section (OR 2.1, 95% CI 1.8-2.4) and instrumental delivery (OR 2.2, 95% CI 1.8-2.6), and deliver low birthweight (OR 1.4, 95% CI 1.3-1.7) and preterm (OR 1.7, 95% CI 1.2-2.2) infants. There were no differences between treatment-related and treatment-independent pregnancies. CONCLUSION: Subfertile women are at higher risk of obstetric complications, which persist after adjusting for age and parity.

Adult↗

Uterine rupture: preventable obstetric tragedies?

BACKGROUND: Although ruptured uterus is nowadays a rare obstetric emergency in Western countries, it is still alarmingly common in developing countries, where it remains a major cause of maternal mortality and morbidity. AIMS: To review the recent experience of uterine rupture at a tertiary obstetric unit in eastern Nepal and to recommend improvements in the current management of labour, especially obstructed labour, in a poorly resourced country. METHODS: All cases of uterine rupture managed from March 2002 to March 2006 were identified retrospectively, and details were retrieved from medical records. RESULTS: Fifty-two women suffered from uterine rupture during the four-year period, approximately one woman per month. Most were unbooked multigravidae, with no antenatal care. They nearly all began labour at home in the absence of a skilled birth attendant. After prolonged labour, usually prolonged second stage, various interventions had often been attempted at home or in other health facilities before admission. Most were shocked and required urgent laparotomy and blood transfusion. Many required intensive care and ventilatory support. Forty-six per cent required hysterectomy and 5.8% subsequently suffered from a urogenital fistula. The maternal mortality rate in this series was 13.5%, and the stillbirth rate was 94.2%. CONCLUSIONS: Unsafe obstetric practices were identified, especially the injudicious use of oxytocic drugs and fundal pressure in prolonged second stage. Several achievable improvements in obstetric care are recommended, particularly aimed at reducing the delay in women reaching emergency obstetric care when labour is prolonged.

Adolescent↗

Incidence and predictors of severe obstetric morbidity: case-control study.

OBJECTIVE: To estimate the incidence and predictors of severe obstetric morbidity. DESIGN: Development of definitions of severe obstetric morbidity by literature review. Case-control study from a defined delivery population with four randomly selected pregnant women as controls for every case. SETTING: All 19 maternity units within the South East Thames region and six neighbouring hospitals caring for pregnant women from the region between 1 March 1997 and 28 February 1998. PARTICIPANTS: 48 865 women who delivered during the time frame. RESULTS: There were 588 cases of severe obstetric morbidity giving an incidence of 12.0/1000 deliveries (95% confidence interval 11.2 to 13.2). During the study there were five maternal deaths attributed to conditions studied. Disease specific morbidities per 1000 deliveries were 6.7 (6.0 to 7.5) for severe haemorrhage, 3.9 (3.3 to 4.5) for severe pre-eclampsia, 0.2 (0.1 to 0.4) for eclampsia, 0.5 (0.3 to 0.8) for HELLP (Haemolysis, Elevated Liver enzymes, and Low Platelets) syndrome, 0.4 (0.2 to 0.6) for severe sepsis, and 0.2 (0.1 to 0.4) for uterine rupture. Age over 34 years, non-white ethnic group, past or current hypertension, previous postpartum haemorrhage, delivery by emergency caesarean section, antenatal admission to hospital, multiple pregnancy, social exclusion, and taking iron or anti-depressants at antenatal booking were all independently associated with morbidity after adjustment. CONCLUSION: Severe obstetric morbidity and its relation to mortality may be more sensitive measures of pregnancy outcome than mortality alone. Most events are related to obstetric haemorrhage and severe pre-eclampsia. Caesarean section quadruples the risk of morbidity. Development and evaluation of ways of predicting and reducing risk are required with particular emphasis paid on the management of haemorrhage and pre-eclampsia.

Adult↗

Unselected women with elevated levels of factor VIII:C or homocysteine are not at increased risk for obstetric complications.

Acquired and hereditary thrombophilias are associated with obstetric complications such as (pre-)eclampsia, HELLP syndrome and fetal loss. Our objective was to assess the risk of obstetric complications in women with elevated levels of FVIII:C or hyperhomocysteinemia, as compared with their relatives who had normal FVIII:C or homocysteine levels. From a large family study of patients with venous thromboembolism or premature atherosclerosis and elevated levels of FVIII:C or hyperhomocysteinemia (propositi), the obstetric histories of female first degree relatives, who had been pregnant at least once, were studied. Levels of FVIII:C and homocysteine (both fasting and post-methionine loading) were determined. The number of obstetric complications was calculated and compared in women with normal and elevated levels of FVIII:C, and normal and elevated levels of homocysteine. Women with elevated levels of FVIII:C had a 15.4% risk for toxicosis, preeclampsia, or HELLP syndrome and a 23.9% for fetal loss. This was not statistically different from women with normal levels of FVIII:C. Women with hyperhomocysteinemia tended to have a lower risk for toxicosis, pre-eclampsia, or HELLP syndrome (8.0%, RR 0.6, 95% CI 0.2-1.7) and fetal loss (22.0%, RR 0.8, 95% CI 0.5-1.5) as compared to relatives with normal levels, although these differences did not reach statistical significance. If the analysis was limited to comparing extremes, the results did not materially differ. Unselected women with elevated plasma levels of FVIII:C or hyperhomocysteinemia are not at increased risk for obstetric complications as compared to their relatives with normal levels.

Adolescent↗

Familial, obstetric, and other clinical correlates of minor physical anomalies in schizophrenia.

OBJECTIVE: This study investigated possible antecedents of minor physical anomalies in schizophrenia, particularly in terms of obstetric and genetic factors, and demographic, clinical and cognitive correlates of such anomalies in schizophrenia. METHOD: Forty-one outpatients satisfying the DSM-III criteria for schizophrenia were examined for minor physical anomalies by using the Waldrop scale. These subjects were drawn from a group of 45 such patients whose cognitive function had been previously evaluated with Trail Making Tests A and B and whose biological mothers had been interviewed for any history of obstetric complications or family history of schizophrenia. RESULTS: Linear multiple regression analysis showed that higher scores for minor physical anomalies were associated with impaired cognitive flexibility on Trail Making Test B, family history of schizophrenia in a first-degree relative, maternal history of obstetric complications, smaller number of siblings, later position in the birth order, and male sex. A family history of schizophrenia was particularly associated with abnormalities of the mouth. The association between minor physical anomalies in the patients and obstetric complications in their mothers appeared to be confined to instances in which the mother had a history of bleeding in early pregnancy. CONCLUSIONS: Minor physical anomalies indicate early dysmorphogenesis in schizophrenia, particularly in males, which appears to be associated more reliably with genetic rather than obstetric factors and with cognitive impairment.

Adult↗

Obstetric adversity and age at first presentation with schizophrenia: evidence of a dose-response relationship.

OBJECTIVE: The purpose of the study was to determine if a dose-response relationship exists between obstetric adversity and age at first presentation with schizophrenia. METHOD: The Dublin Psychiatric Case Register was used to identify subjects with schizophrenia. Data on obstetric complications, social class of origin, and family history of psychiatric illness were obtained for those subjects. RESULTS: A total of 409 patients with ICD-9 schizophrenia were identified. Patients with a history of obstetric complications presented earlier to psychiatric services. As the number of complications increased, the mean age at first presentation decreased. This effect was independent of social class of origin and family history of psychiatric illness. CONCLUSIONS: Obstetric adversity exerts an independent influence on the age at first presentation with schizophrenia, in a dose-response manner. This finding supports the existence of a causal relationship between obstetric adversity and age at first presentation with schizophrenia.

Adult↗

Training in obstetric sonography for radiology residents and fellows in the United States.

OBJECTIVE: The purpose of our study was to assess the current experience of radiology residents and fellows in obstetric sonography. SUBJECTS AND METHODS: Written surveys were sent to the directors of 206 accredited radiology residency programs and 85 fellowship programs in the United States. The surveys encompassed obstetric sonographic experience during routine working hours and after hours, the level of supervision, the types of scanning performed, and the extent of formal lectures available during training. Additional questions concerned the relative knowledge of laboratory accreditation processes and training of faculty covering obstetric sonography. RESULTS: Sixty (29%) of 206 accredited radiology residency programs and 24 (28%) of 85 fellowship programs returned surveys. The experience among residency programs was similar, providing fewer than 4 weeks per year of obstetric sonography, usually within their own department of radiology. Residents were more likely to be sent to outside departments for second or third trimester sonography experience. A decrease in scanning assistance was reported for examinations performed after hours, more so for second or third trimester studies. Lecture topics revealed similar deficiencies for residency and fellowship programs. CONCLUSION: Greater emphasis on the performance of prenatal sonographic examinations may be warranted during formal sonography rotations. Current levels of experience in obstetric sonography may not be providing sufficient experience to allow residents to appropriately manage call cases or for practicing radiologists to provide such services after their training is completed.

Data Collection↗

Obstetric outcome in 100 women with severe anxiety over childbirth.

BACKGROUND: Extreme fear of delivery with request of cesarean section is a problem. The obstetric outcome in women given psychological and obstetric support is described. METHODS: Women, consecutively referred to the Psychosomatic outpatient clinic because of fear of delivery (n = 100), were compared to a matched reference group (n = 100). RESULTS: The women in the study group had higher frequency of psychic problems than the references. The majority, 68 of the women (68%) initially requested cesarean section (CS). After individualized psychological and obstetrical support, 38 of these women agreed to vaginal delivery (38%) and 30 had an elective CS (30%). In the end another 13 (13%) women had a CS for obstetric or mixed reasons. Complication rate was low and similar in the groups. The 57 women who eventually had a vaginal delivery (57%) showed an obstetric outcome similar to the reference group. They had a higher frequency of induction of labor (p = 0.02). and of epidural and pudendal blocks for pain relief (p = 0.002 and 0.05 respectively). They had shorter labor time (p = 0.05). The cost of the psychological therapy was well compensated for by the savings due to the reduction in the number of CS. CONCLUSIONS: Psychosomatic support for women with severe fear of delivery resulted in a 50% reduction of CS for psychosocial indications and vaginal deliveries similar to a reference group. The cost of psychosomatic support was less than savings due to fewer cesarean sections.

Adult↗

Cost consequences of implementation of an early obstetrical discharge programme in a military teaching hospital.

We evaluate the cost consequence of a voluntary early obstetrical discharge programme in a military teaching hospital. The study involved a control group of routine obstetrical discharge patients with uncomplicated vaginal delivery from March 1 to August 31, 1994 and the study group of early obstetrical discharge (24-48 hours) patients with uncomplicated vaginal delivery from March 1 to August 31, 1996. There were 1,042 total control patients with routine vaginal delivery totalling 2,668 hospital days with a mean number of hospital days of 2.56 per patient. The study group of early obstetrical discharge patients with uncomplicated vaginal delivery encompassed 1,050 patients with 1,965 hospital days with mean hospital days of 1.87 per patient (p < 0.05) without an increase in postpartum clinic or emergency room visits. The total cost of admissions (cost calculation of $1,221 per hospital day) fell from $3,257,628 in the routine discharge group to $2,399,625 in the early discharge cohort showing a total cost savings of $858,003 over the 6-months study period. The average cost per obstetrical admission for routine vaginal delivery fell from $3,126 per day to $2,285 per day without an increase in the postpartum paediatric adverse outcomes. Maternal postpartum readmission rates were statistically significantly increased (p < 0.05) in the study group at 0.6% with an OR[2.32(2.17, 6.92)] but all readmissions fell outside the 48-hour early discharge window. This programme showed significant cost savings without concomitant increase in paediatric or maternal adverse outcomes.

Aftercare↗

[A proposed protocol for obstetrical ultrasound examination].

INTRODUCTION: Ultrasound has a number of valuable functions in obstetrics including dating, confirming viability, counting the number of fetuses and the exclusion of gross fetal anomalies. During two routine obstetric ultrasound scans, between 11 and 14 gestational weeks and around 20 weeks, the fetus should be carefully examined after which the existence of anomalies can be confirmed or, with a limited certainty that ultrasound enables, excluded. In order to obtain high standards of ultrasound screening, a uniformed protocol is needed, which would enable standardized examination. In this paper the Novi Sad University Department of Obstetrics and Gynaecology presents a new protocol for ultrasound examination which would ensure standardized ultrasound scanning and adequate record keeping. MATERIAL AND METHODS: The protocol is based on contemporary recommendations of the Royal College of Obstetricians and Gynaecologists of Great Britain, the Royal College of Radiologists of Great Britain, the American College of Obstetricians and Gynaecologists, as well as protocols used in routine ultrasound examinations of low-risk population (1,2,3,4,5,6). RESULTS: There are two protocols: one for scanning in the first and the other in the second/third trimester. All the findings are recorded in adequate forms. In the first trimester number, viability, gestational age and expected date of delivery are established (4,6). At the end of the first trimester an anomaly scan can be performed as well (8,9,10,11,12). It includes measuring of crown-rump length, nuchal translucency and fetal heart rate, and examination of placenta, skull, brain, spine, abdomen, stomach, bladder and upper and lower extremities. An adjusted risk of chromosomal abnormality is given, based on maternal age and nuchal translucency measurement. In the second and third trimester the usual fetal biometry is performed as well as a detailed scan of anatomy, which includes searching for ultrasound markers of chromosomal abnormality. At 23 weeks the transvaginal evaluation of cervical length is performed, in an attempt to screen for women at risk of preterm delivery. A new, adjusted risk of chromosomal risk can be given, based on maternal age, nuchal translucency measurement in the first trimester and presence/absence of ultrasound markers of chromosomal abnormality. DISCUSSION: Ultrasound in obstetrics has a major role. All scans in pregnancy must have clear aims, which in early pregnancy are (2): establishing fetal viability; establishing gestational age; identification of multiple pregnancies and their horionicity; exclusion of major fetal anomalies; psychological support and in second trimester are (4,13): (1) establishing normal ultrasound appearances of the fetus, which does not mean that the fetus is normal. The expression 'normal' should be avoided because of possible medico-legal implications. (2) identification of: anomalies incompatible with life; anomalies linked with high morbidity and long-term handicap; fetal conditions than that can be treated during intrauterine life; fetal conditions that will need postnatal tests and therapy. CONCLUSION: New protocol and forms will enable an easier systematic obstetric ultrasound examination.

Female↗

Womens' perceptions regarding obstetric complications and care in a poor fishing community in Karachi.

OBJECTIVE: To assess the knowledge of women about obstetric complications and care. METHODS: The study was conducted in a remote coastal community in Karachi in 1999, where the Department of Community Health Sciences of Aga Khan University is operating its primary health care project since 1996. The information was collected using a structured questionnaire, interviewing a representative sample of 329 married-women of reproductive age, selected systematically from the community. RESULTS: The mean age of the respondents was 29 years. On average they were married for 11 years and had four living children. Almost half of them had no antenatal care in their last pregnancy and 75% delivered at home. The findings indicate a poor knowledge of common and serious pregnancy related complications based on their perception related to danger signs. Five percent of the women perceived absent/decreased fetal movement as a danger sign of pregnancy. Other reported danger signs included premature uterine contraction by 3%, premature rupture of membranes by 3%, convulsions by 13%, obstructed labor by 23% and bleeding by 39%. Moreover, the women's perception regarding obstetric care suggests that unsafe practices prevail: 86% of women thought that a case of ante-partum hemorrhage should be examined internally and 50% thought that no precaution is required to sterilize the instrument for cutting the cord. CONCLUSION: There is a clear need to create awareness regarding obstetric complications through a targeted community based health educational intervention aiming to promote early recognition of the obstetric emergency at the household level and also to create a demand of safe obstetric practices.

Adult↗

Postnatal morbidity after childbirth and severe obstetric morbidity.

OBJECTIVE: To identify the impact of pregnancy and childbirth, and severe obstetric morbidity on outcome 6 to 12 months postpartum. DESIGN: Questionnaire assessment of postnatal outcome in a cohort study. SETTING: South East Thames, UK. POPULATION: All women resident in South East Thames and delivering between 1st March 1997 and 28th February 1998. METHODS: Questionnaire study of a cohort of women who experienced a severe obstetric morbidity during pregnancy or labour (cases), compared with a cohort of women who did not (controls). MAIN OUTCOME MEASURES: Assessment of postnatal depression risk [Edinburgh Postnatal Depression Scale (EPDS)], general health [Short Form 36 (SF-36)], sexual activity and use of health services between 6 and 12 months postpartum. RESULTS: There were 331 cases and 1339 controls out of 48,262 deliveries. Six to 12 months after delivery, 77 (23.3%) of cases and 272 (20.5%) of the controls were at risk of postnatal depression (P = 0.25; 95% CI for difference -2.2% to 7.9%), 43.1% of cases were having problems with sexual relations compared with 18.7% of controls (P < 0.001; 95% CI for difference 8.9% to 21.9%). There was evidence of poorer general health in cases. Some 31.5% of cases attended outpatients in the first six months and 9.4% required emergency admission to hospital compared with 17.0% (P < 0.001; 95% CI for difference 9.1% to 19.9%) and 3.7% (P < 0.001; 95% CI for difference 2.4% to 9.0%), respectively, in controls. CONCLUSION: Both control pregnancy and childbirth and severe obstetric morbidity are associated with significant postnatal morbidity. A severe obstetric morbid event significantly influences women's sexual health and wellbeing and increases health services utilisation. Prevention and appropriate management of severe obstetric morbid events may reduce these outcomes.

Case-Control Studies↗

[Clinical studies on imipenem/cilastatin sodium in the field of obstetrics and gynecology].

The efficacy and safety of imipenem/cilastatin sodium (IPM/CS) were studied in patients with obstetric and gynecologic infections and in those given the drug as prophylaxis against postoperative infections. The following results were obtained: 1. Efficacy rates were 96.0% (48/50) in patients with obstetric and gynecologic infections and 100% (28/28) in those with urinary tract or other infections. The overall efficacy rate was 97.4% (76/78). Bacteriologically, 30 organisms were isolated from 28 patients. The eradication rate was 95.2% (20/21) and the efficacy rate was 96.4% (27/28). 2. Changes in blood elastase before and after treatment were compared with those in CRP, WBC, and ESR in the patients with obstetric and gynecologic infections. The changes in elastase were similar to those in CRP. 3. The efficacy rate was 98.0% (48/49) in the patients given prophylaxis against postoperative obstetric and gynecologic infections. 4. An adverse reaction was observed in only one patient (diarrhea), and abnormal laboratory findings were noted in 2 patients (elevation of GOT and GPT). These results indicate that IPM/CS is very useful for the treatment of obstetric and gynecologic infections.

Adolescent↗

Hepatitis B in obstetric patients in the community hospital: the need for screening.

A prospective survey was conducted in a 200-bed community hospital that averages approximately 250 deliveries per month. One hundred consenting obstetric patients were screened for hepatitis B surface antigen (HBsAg). Additionally, hospital physicians were encouraged to order an entire hepatitis serological profile on high-risk obstetric patients, as defined by the Centers for Disease Control; six additional patients were screened by these physicians. Of the 106 patients screened, two (1.9%) were found to have HBsAg. Both were among the six high-risk patients, indicating a 33% prevalence of HBsAg among high-risk obstetric patients and a zero prevalence among low-risk patients. The results appear to support the need for screening of high-risk obstetric patients for hepatitis B. Moreover, vaccination against hepatitis B is advisable for obstetric health-care personnel, who are frequently exposed to blood and extravascular fluids.

Female↗

Obstetric outcome before and after metroplasty in women with uterine anomalies.

A review of 49 patients with uterine anomalies was made to determine the relationship of anomalies to infertility, to obstetric outcome, and to indications for surgical reconstruction (metroplasty). For 41 of the 49 patients with obstetric histories, the overall pregnancy wastage was 72%, with bicornuate and septate patients having 85 to 90% wastage. The 28% of pregnancies that were successful were largely accounted for by patients with didelphic anomalies. It was found that infertility was an uncommon problem in these patients and it should rarely be an indication for metroplasty. In 21 patients properly selected for metroplasty because of repeat pregnancy loss, the obstetric outcome improved from 7% successful pregnancies before surgery to 75% postoperatively. Patients with septate or bicornuate anomalies were found to be poor obstetric performers and likely candidates for repair, while patients with didelphic anomalies achieved obstetric satisfaction without surgical intervention.

Classification↗