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Results for “Maxillary Neoplasms”

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At least 649 records · Page 36Linked to original sources
PubMed1975

Radical excision and reconstruction in advanced maxillofacial carcinomas.

Some problems on excision and reconstruction in maxillofacial cancer surgery were briefly discussed and three representative cases presented. One innovation presented concerned the use of an almost circular cheek skin flap containing branches of the superficial temporalis artery preserved intact.

Adult↗
PubMedDate not supplied

Sarcoma of the maxillofacial region: follow-up of 25 cases.

BACKGROUND: Maxillofacial sarcomas are rare tumors, varying according to their type, grade, site of occurrence, response to treatment and prognosis. Approximately 10% of all cases of osteosarcoma, a subtype with a particularly poor prognosis, occur in the head and neck. PATIENTS AND METHODS: During the 35 years from 1963 until 1997, the 25 patients treated for sarcomas at our center were identified and evaluated according to a variety of parameters. RESULTS: Overall 2- and 5-year survival rates were 72% and 60%, respectively. Sarcomas were found most commonly in the mandible, maxilla and tongue. Survival was not significantly correlated with gender, ethnic origin or histopathological staging, but significant correlation was found between type of sarcoma and survival whilst younger patients had better survival rates. CONCLUSION: Advanced facial reconstruction methods may enable the performance of more radical ablative surgery, thereby improving survival outcome for head and neck osteosarcoma patients. Osteosarcoma appears to be as lethal in the maxillofacial region as in the extremities.

Adolescent↗
PubMed2000

Expression of cell cycle-associated proteins CDK4, p27, and E2F-1 in chondrosarcoma of the jaws.

OBJECTIVE: To elucidate the expression and significance of cell cycle-associated proteins in chondrosarcoma of the jaws. METHODS: CDK4, p27, and E2F-1 expression were examined in chondrosarcoma and osteochondroma of the jaws by immunohistochemical ABC method. RESULTS: CDK4, p27, and E2F-1 were positive in 60% (12 of 20), 25% (5 of 20), and 65% (13 of 20), respectively, in chondrosarcoma of the jaws. There was no significant difference in the expression of CDK4, P27, and E2F-1 among histological grade of the chondrosarcoma (P > 0.05). In osteochondroma of the jaws, CDK4 and E2F-1 showed an equal positivity of 12.5% (1 of 8), whereas p27 was positive in 87.5% (7 of 8). The positive rate of CDK4, p27, and E2F-1 was significant between chondrosarcoma and osteochondroma of the jaws (P < 0.05). CONCLUSION: These data show that cell cycle regulatory proteins are altered in chondrosarcoma of the jaws. CDK4 and E2F-1 are over-expressed and p27 is under-expressed in chondrosarcoma of the jaws.

Adaptor Proteins, Signal Transducing↗
PubMed2000

Paediatric oral surgical pathology service in an African population group: a 10 year review.

The records of the Oral Pathology Services of the University College Hospital Ibadan Dental Centre contains data on 2264 biopsies between 1986-1996. There were 561 biopsies on patients aged 1-16 years representing 16.2% of total. Case notes and radiographs (where available) were retrieved and analysed for diagnosis, sex, age and site. For convenience, tissue pathology was compartmentalised into, Neoplasm (benign and malignant), cysts, and inflammatory/reactive. Neoplasm constitutes the highest with 47.6%, followed by inflammatory/reactive 27.6% and cystic lesions at 24.8%. A significant preference for male over female was noted and the mandible was also the site of preference for most of the lesions.

Adolescent↗
PubMed1999

[Adenomatoid odontogenic tumor and a suborbital premolar. Apropos of a case].

One case of a voluminous cyst developed into the maxillary sinus associated with an infra-orbital location of embedded upper premolar is reported. The authors point out this rare location of an embedded upper premolar, the radio-clinic differential diagnosis and the possible association between the adenomatoïd odontogenic tumour and the dentigerous cyst. A CT-Scan examination showed a large maxillary radiolucent image under a tooth in infra-orbital localization. Histological examination revealed the lesion to be adenomatoïd odontogenic tumour. Complete enucleation of the cyst and extraction of the tooth were performed by oral way with success.

Adult↗
PubMedDate not supplied

Calcifying odontogenic cyst. Report of two cases.

Calcifying odontogenic cyst(COC) is an uncommon developmental odontogenic cyst and was first described by Gorlin in 1962. It is considered as extremely rare and accounts for only 1% of the jaw cysts reported. Here, we present two cases of which one occurred in a 32 year old female with a swelling in the lower anterior region crossing the midline and another in a 29 year old male with a swelling in the upper anterior region without crossing the midline. The radiograph revealed a well circumscribed radiolucency in the first case and with some specks of opacities in the second case. It was not associated with any missing or impacted tooth. Histopathological examination was done with Hematoxylin and Eosin and in addition it was studied immunohistochemically for cytokeratin. The Classical histological features of lining epithelium in the form of cords, presence of ghost cells and some amount of dentinoid tissue were seen. The nature of COC is controversial. Here we have discussed the controversies regarding COC as well as the various proposed classifications for this lesion. Based on the histopathological findings, the diagnosis was confirmed as calcifying odontogenic cyst. These cases are presented here for its rarity.

Adult↗
PubMedDate not supplied

Myxoma of the jaws. Report of three cases.

Odontogenic myxoma is a locally aggressive, uncommon benign tumour which arises from mesenchymal tissues normally present in developing teeth. The most frequent locations of odontogenic myxoma are the posterior regions of the mandible, as well as the condylar region. Since odontogenic myxomas are not associated with any specific clinical or radiological sign, a histopathological examination of the specimen is required for confirmation of the primary diagnosis. We report three cases of myxoma diagnosed during the last 18 years. Two of them were located in atypical regions of the mandible and one was located in the maxilla. Presence of a slow-growing swelling associated with expansion of the bone plates raised suspicion of a tumour in two cases, while in the third patient the myxoma was an incidental finding during radiological examination. Due to the unspecific nature of these lesions, in every case a histopathological examination of the surgical specimen was required for diagnostic confirmation. In one of the three reported cases, we shall underline the need to follow a correct diagnostic work-up of all radiolucent lesions of the jaws, in order to avoid contraindicated therapeutic procedures.

Adult↗
PubMed2000

Unusual jaw lesions in the paediatric and adolescent patient: a management challenge.

While major maxillofacial pathology in the young patient is relatively uncommon, non-malignant conditions may pose a significant treatment dilemma due to their aggressive or unpredictable behaviour. Several such diseases managed by the Oral and Maxillofacial Surgery Unit at the Royal Children's Hospital of Melbourne have been selected for review. Illustrative case reports to highlight the principles of management are presented.

Adolescent↗
PubMedDate not supplied

Dynamic multislice helical CT of maxillomandibular lesions: distinction of ameloblastomas from other cystic lesions.

PURPOSE: To evaluate the clinical usefulness of dynamic multislice helical CT in differentiating ameloblastoma from other cystic lesions in cases of maxillomandibular cystic lesions. MATERIALS AND METHODS: The study included 32 patients with maxillomandibular cystic lesions (ameloblastoma [n=6], myxofibroma [n=1], odontogenic keratocyst [n=3], dentigerous cyst [n=11], radicular cyst [n=11], and paradental cyst [n=2]). Dynamic study was performed before and 30 sec, and 90 sec after intravenous contrast medium administration. CT density values and percentage of density increase were calculated at 30 and 90 sec. RESULTS: In five cases of ameloblastoma, a rapidly enhancing area was detected within the cystic lesions at 30 sec, while no apparent rapid enhancement was seen in the other cystic lesions. Three cysts showed gradual enhancement in the marginal area at 90 sec. Comparing ameloblastoma and other kinds of cysts, we found significant differences in the percentage of density increase at 30 sec (p<0.01) and 90 sec (p<0.05). CONCLUSION: Dynamic multislice helical CT is useful in the diagnosis of cystic lesions of the maxillomandibular region, especially in the detection of neovascularities in ameloblastoma.

Adult↗
PubMed1975

[Results of primary and combined radiotherapy of mouth carcinomas (tongue, tonsil, maxilla, mandible, palate, floor of the mouth cheek mucosa)].

Responses to highvoltage radiotherapy of 320 patients with carcinomas of the oral cavity are discussed. Five year survival rate according to the stage of the, disease were the following ones: in carcinoma of the anterior 2/3 of the tongue and floor of the mouth 20-60%, buccal mucosa, upper and lower jaw 30-50%, base of the tongue 26% and tonsil 30-100%. After simultaneous irradiation of the efferent lymphatics in parimary N0 patients, whose primary tumor subsequently was under control, a significantly lower frequency of metastases to the lymph nodes was found than without coirradiation of the lymph flow. Clinically verifiable metastases of the lymph nodes are also controllable to a high percentage by radiotherapy alone: Only in a little more than five per cent of the primary N1-3 patients with the parimary tumor being under control, additional metastases of the lymph nodes developed later on. The complication rate was 6.8 per cent. Most frequently, osteonecrosis was involved, indeed occurring chiefly in cases, where a primary skeletal manifestation of the tumor already was existing.

Bone Neoplasms↗
PubMedDate not supplied

Neurofibromatosis type 1: a clinicopathological study of the orofacial manifestations in 6 pediatric patients.

Neurofibromatosis type 1 (NF1) is a relatively frequent mucocutaneous syndrome, which is transmitted as an autosomal dominant trait or which may represent neomutation. It is characterized by a variety of clinical manifestations, including multiple neurofibromas that are associated with a high risk of sarcomatous transformation. The aim of this report was to elucidate the orofacial manifestations observed in 6 pediatric patients (between 4 and 15 years of age) diagnosed with NF1. Physical, clinical, radiological, histological, and immunohistochemical studies were performed. Orofacial lesions were observed in all studied patients, located either in the soft tissues (4 cases) or centrally in the jaws (2 cases). All cases showed facial asymmetry, one of them exhibiting marked facial hemihypertrophy. All cases with soft tissue involvement were plexiform neurofibromas, while the intraosseous cases were diagnosed as solitary neurofibromas. Knowledge of the variability of presentation of orofacial soft tissue and bone manifestations of NF1 in children is necessary for prompt diagnosis.

Adolescent↗
PubMedDate not supplied

Juvenile aggressive cemento-ossifying fibroma. A case report.

Juvenile Aggressive Cemento-Ossifying Fibroma is a benign, fibro osseous neoplasm commonly affecting maxilla but also other bones including mandible, arising in children. It is considered to be a locally aggressive and quickly expansile lesion. Because of its aggressive nature and high recurrence rate, an early detection and a complete surgical excision is essential. A case of Juvenile Aggressive Cemento-Ossifying Fibroma in a 9 year old male child who visited the Department of Oral Medicine and Radiology, J.S.S. Dental College and Hospital, Mysore is being reported and discussed.

Child↗