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[Manometry studies of continence performance in patients following gracilisplasty].

Out of a total of 10 patients who had undergone a Pickrell-procedure of the gracilis muscle from 1970-1980, 6 were now followed-up by clinical examination and perfusion manometry of the anal canal. The manometric parameters were compared with an anamnestic score. For anal continence the degree of resting activity of the transposed gracilis muscle is in our opinion not decisive. For that reason, there is no necessity for a permanent contraction.

Adolescent↗

Endoscopic electromyography and manometry of the human sphincter of Oddi.

The myoelectric and manometric activities of the sphincter of Oddi were recorded in 8 patients using an original probe passed through the papilla of Vater during duodenoscopy. The sphincter of Oddi's myoelectric activity showed rhythmic bursts of action potentials which appeared in correspondence with the ascending phase of the phasic pressure waves. On the basis of these results, we believe that electromyography could in some cases replace manometry for studying sphincter of Oddi motility, since it avoids pressure perfusion of the bilio-pancreatic tract, with its concomitant risks, and provides sufficient information for motor studies.

Ampulla of Vater↗

Age and sex dependency of bile duct diameter and bile duct pressure--an ERC manometry study.

Using ERC-manometry diameters of the common bile duct (CBD) the common hepatic duct (CHD) as well as CBD pressure before and after opacification were determined in 35 non-cholecystectomized patients without extrahepatic cholestasis. We found a significant rise of both CBD and CHD diameters as well as CBD pressure recorded before the injection of contrast medium with increasing age. (p less than 0.005, less than 0.001 and less than 0.05 respectively). Following the opacification CBD pressure became elevated. Again this increase tended to be more pronounced in older patients although this association was lacking statistical significance. In the presence of comparable age female patients (n = 16) exhibited higher CBD and CHD diameters (n.s.) as well as CBD pressure values (p less than 0.05) than male patients (n = 19). We conclude that in the absence of extrahepatic cholestasis bile duct diameter as well as bile duct pressure rise significantly with increasing age. Furthermore women tend to have higher diameters and pressure values than men.

Adult↗

[Late complications of Hirschsprung's disease and anorectal manometry].

In 84 patients treated with Soave-Denda method, informations of their bowel habits were obtained through a questionnaire. These patients were classified into 4 groups (A; less than 3 years, B; 3 to 6 years, C; 7 to 9 years and D; more than 10 years after the operation) and analyzed by comparing their bowel habits with those of normal children in corresponding age group. Some late complications were demonstrated although 80% of patients followed for more than 10 years had a normal bowel habit. Frequent incontinence (more than once a week) was found in 18.2% of group B and 5% of group C. No patients has incontinence in group D. Frequent soiling (more than once a week) was demonstrated in 58.8% of group B, 30% of group C and 23.1% of group D although the incidence of frequent soiling ranged from 0.5 to 2.1% in normal children of these age group. Manometry to detect a rectonal reflex was useful to evaluate anorectal function because patients who showed normal reflex had excellent bowel habits without incontinence. These unexpected high incidence of late complications indicate that postoperative training of defecation is extremely important to give normal bowel habit to the patients with Hirschsprung's disease.

Adolescent↗

[Esophageal manometry in patients with sliding hiatal hernia].

This presents the method to be followed for the valuation of the gastro-esophagic function in patients with sliding hiatal hernia, twenty-one patients with this diagnosis were studied through X-Rays. Besides gastric and esophagic endoscopy, a complete clinical examinations was made to compare the information obtained from the studies, with the direct measurement of the contractions of the esophagus and the lower sphincter through conventional manometric methods. The relationship between the simptoms and the clinical procedures done in the patients were observed as was the usefulness of esophagic manometry to detect not only the direct pressure of the gastro-esophagic sphincter, but also to determine the concurrent motor changes that can occur in patients which show hiatal hernia. The benefit of this studies to decide the therapeutic handling, specially surgical, is discussed.

Esophagogastric Junction↗

[Method of measuring pressure using perfusion manometry].

Based on the principle of perfusion manometry, a device for the assessment of intraluminal pressures in urethra and anal canal is presented. The technical parameters are reported. The method may be utilized for clinical diagnosis in cases of disturbed micturition and defecation in children as well as for the function of esophagus.

Anal Canal↗

Endoscopic electrosurgical papillotomy and manometry in biliary tract disease.

Endoscopic papillotomy was performed in 13 patients after cholecystectomy for retained or recurrent common bile duct calculi (11 patients) and a clinical picture suggesting papillary stenosis (two patients). Following endoscopic papillotomy, ten of the 11 patients spontaneously passed common bile duct (CBD) stones verified on repeated endoscopic retrograde cholangiopancreatography (ERCP) study. One patient failed to pass a large CBD calculus; one patient experienced cholangitis three months after in inadequate papillotomy and required operative intervention. Endoscopic papillotomy substantially decreased the pressure gradient existing between the CBD and the duodenum in all five patients studied with ERCP manometry. Endoscopic papillotomy is a relatively safe and effective procedure for postcholecystectomy patients with retained or recurrent CBD stones. The majority of CBD stones will pass spontaneously if the papillotomy is adequate.

Ampulla of Vater↗

[Value of manometry in establishing the developmental stage of portal hypertension and the effectiveness of therapeutic portacaval shunt].

A total of 105 patients have been studied, operated for portal hypertension, that underwent porto-manometric investigations by various methods, before and during surgery. The study was aimed at establishing indications that can be provided by portal manometry on the evolutive stage of portal hypertension. Correlations have been established between ascitic decompensation, the frequency of superior digestive hemorrhages and the portal pressure. The efficiency of the post-systemic derivation was evaluated manometrically, depending on the type of the anastomosis. Conclusions are presented, on the particular value of the manometric investigation for the correct choice of the porto-caval shunt.

Humans↗

Endoscopic manometry of the sphincter of Oddi in patients with and without juxtapapillary duodenal diverticula.

The motor activity of the sphincter of Oddi (SO) has been evaluated, by endoscopic manometry, in 48 subjects, 8 with and 40 without duodenal juxtapapillary diverticula. All values were expressed in mm Hg, taking duodenal pressure as zero reference. In subjects with diverticula the SO basal pressure was 14.1 +/- 4.3 mm Hg, peak pressure was 52.3 +/- 17.2 mm Hg, and wave height was 39.75 +/- 14.19 mm Hg; in subjects without diverticula these values were 31.2 +/- 8.9 mm Hg, 93.2 +/- 21.3 mm Hg, and 68.17 +/- 25.86, respectively. The difference was statistically significant (P less than 0.001 for basal and peak pressure; P less than 0.002 for wave height). Wave frequency was not significantly different in controls (4.99 +/- 1.17/min) and in subjects with diverticula (4.98 +/- 1.13/min). These findings seem to indicate that in patients with diverticula the SO is insufficient or dysfunctioning . The insufficiency of the SO and a reflux of bacteria from the duodenum into the bile duct could play a major role in the formation of stones in patients with diverticula. The same mechanism could be responsible for duodenopancreatic reflux and possible pancreatic lesion.

Adult↗

Laparoscopic transhepatic manometry in portal hypertension in patients with alcoholic liver damage.

Liver damage influenced by alcohol is already associated with the development of a portal hypertension at an early stage. With the aid of laparoscopic transhepatic manometry we determined the pressure levels in the branches of the portal and hepatic veins in 15 patients (16 examinations) comprising 14 men and 1 women, with alcoholic toxic liver damage. It was shown that already with alcoholic parenchymal damage associated with portal and centrolobular fibrosis, a portal hypertension is initiated, the greatest manifestation of which is found in the group with histological changes taking the form of a remodelling (distorsion of architecture) or cirrhosis. The level of alcohol consumption has no direct influence on the level of pressure in the vascular systems investigated. Ther is, however, a correlation between the level of alcohol consumption, extent of fibrosis and portal hypertension. For the clinico-chemical parameters investigated (Gamma-glob., GOT, GPT, GLDH, gamma-GT, alkaline phosphatase, bilirubin) no significant differences were found dependent on the level of alcohol consumption or the degree of fibrosis.

Adult↗

Intraoperative sphincter of Oddi manometry in patients with gallstones.

In seven patients operated on with cholecystectomy for simple gallstones, sphincter of Oddi manometry was performed during surgery. The sphincter was localized as a zone with elevated base-line pressure and phasic contractile activity. Mean value of the amplitude was 90 mm Hg; wave duration, 4 sec; frequency, 5/min; and base-line pressure, 10 mm Hg. No activity was seen in the antrum or duodenum. The plotting of peak-to-peak intervals in a histogram showed that these were evenly distributed around 6 sec or at integrated multiples of this value. This indicates that the sphincter of Oddi is paced. The origin of the pacing is not yet established.

Adult↗

[Intra-operative manometry and hiatal hernia].

Personal experience of the intra-operative use of oesophageal manometry in cases of hiatus hernia is presented. Using this system the pressure in the air cushion surrounding the L.E.S. can be adjusted to avoid any complications due to overtight or overlax surgery. Various types of post-operative tests confirm the value of the technique.

Esophagoscopy↗

Esophageal Manometry in Patients with Chest Pain and Normal Coronary Arteriogram.

Evaluation of the esophagus is helpful in determining the source of chest pain. Eighteen per cent of 72 patients with a normal coronary angiogram had esophageal disease as a source of chest pain. Eight had diffuse esophageal spasm, four had reflux esophagitis and one had an esophageal ulcer. Five of eight patients with diffuse esophageal spasm had relief of symptoms with nitroglycerin. Despite normal coronary arteriogram and normal esophageal manometry 42 of 49 other patients had relief of chest pain with nitroglycerin.

Adult↗

Direct choledochography and related diagnostic methods. Part 2: Sphincter of Oddi manometry.

Pressure measurement of the sphincter of Oddi segment during ERCP has enhanced the current understanding of normal biliary-pancreatic tract motor physiology as well as the effects of drugs and hormones. ERCP manometry has also provided information about SO function in pathological conditions in humans, such as bile duct stones, SO stenosis and SO dyskinesia. Finally, SO pressure measurements appear to be helpful in identifying patients with symptomatic SO dysfunction who will derive benefit from endoscopic sphincterotomy or surgical sphincteroplasty.

Ampulla of Vater↗

Anorectal manometry: a new simplified technique.

Several noninvasive techniques using anal balloons or catheter systems to measure anal sphincter function associated with rectal balloon distention have been used in differentiating functional constipation from aganglionic megacolon. We have developed a simplified method for anorectal manometry that uses a microtip pressure transducer to record anal sphincter responses. Seventy-three patients (51 children and 22 adults) with constipation have been studied with this technique. Normal responses of internal anal sphincter relaxation to rectal distentions were obtained in 60 patients (40 children and 20 adults), consistent with the diagnosis of functional constipation. Abnormal responses-no internal anal sphincter relaxation-were recorded in 13 patients (11 children and two adults), consistent with the diagnosis of Hirschsprung's disease. The manometric diagnosis was confirmed in all 21 patients biopsied. There were no false-positive or false-negative results. The technique is a simple, well tolerated, and rapid method for assessing anal sphincter function.

Adolescent↗

[Value of digestive manometry in scleroderma of childhood].

The authors report a case of systemic scleroderma in a 7 year-old boy, with digestive, cardiac and cutaneous involvement. They stress for the first time the pediatric significance of esophageal and recto-anal manometry from an etiologic topographic point of view.

Child↗

[Percutaneous transhepatic radiomanometry of the bile ducts (PTC-manometry) (author's transl)].

Method and first results of the PTC-manometry are shown in 32 cases. Low residual pressures in bilio-digestive anastomosis and high results both in incomplete bile obstruction and in anicteric patients with incomplete stenosis of the common bile duct and with papillary stenosis suggest a clinical importance. In connection with clinical symptoms and x-ray results it is possible to give informations already preoperatively which we could got only by intraoperative radiomanometry till now. There was no correlation between the maximum size of the common bile duct and the residual pressure.

Adult↗

[Biofeedback and esophageal manometry. Preliminary note].

The biofeed-back technique is based on the concept of the voluntary control of visceral functions and derives from the clinical application of the theory of operative conditioning. After a brief mention of general concepts and the various application fields of biofeed-back, a personal proposal for the use of this technique in the treatment of oesophageal dysfunctions of psychosomatic origin with the aid of oesophageal manometry is put foward.

Animals↗