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Genomic comparison using data mining techniques based on a possibilistic fuzzy sets model.

Current copiousness of genomic information stored in biological databases [Mar Albà, M., Lee, M., Pearl, D., Shepherd, F.M.G., Martin, A.J., Orengo, N., Kellam, C.A., 2001. P. VIDA: a virus database system for the organisation of virus genome open reading frames. Nuleic Acids Res. 133-136] makes ultimately feasible the proposal for an application of knowledge management aimed to discover general rules in subcellular phenomena. The goal of this work is primarily to discover relationships between genes by microarray analysis. The tools exploited come from clustering techniques and are mainly based on Knowledge Discovery in Databases (KDD) concepts [Fayyad, U., Piatetsky-Shapiro, G., Smyth, P., 1996. From data mining to knowledge discovery in databases. AI Magazine 17(3), 37-54]. Starting from a data set, each element can be represented by a characteristic matrix, which sums up all data attributes. In this case data mining is oriented to perform a Pattern Recognition of related sequences, hidden in databases [Hand, D.J., Nicholas, A., 2005. Heard finding groups in gene expression data. J. Biomed. Biotechnol. 215-225]. Following a bottom up approach, the next refinement is to compare retrieved data to gather similar features, by dedicated clustering algorithms [Kaufman, L., Rousseeuw, P.J., 1990. Finding groups in data. An Introduction to Cluster Analysis. John Wiley & Sons, New York; Forman, G., Zhang, B., 2000. Distributed Data clustering can be efficient and exact HP. Laboratories Palo Alto HPL-2000, p. 158], driven by fuzzy logic, allowing us to perceive by intuition a common denominator for various genomic families and to anticipate likely future developments.

Algorithms↗

Physician-assisted weight loss and maintenance in the elderly.

Although commonly addressed in magazines, across airwaves, and within gyms nationwide, health care providers must now face the growing epidemic of obesity in their daily practice. With the graying of America, it is all the more important to realize that weight increases the risk for disease and mortality in the elderly. Despite overwhelming evidence that weight loss can reduce health risks, many patients who are overweight never receive needed advice from their primary care physicians. This article addresses the barriers to physician intervention, methods to assess obesity risk, and readiness to change. Effective approaches for assisting in successful weight loss and maintenance are discussed.

Aged↗

Psychosocial aspects of beauty: how and why to look good.

It is difficult to pick up a paper or magazine today or turn on the television without being reminded that ours is a culture of youth and beauty. Bookstore shelves sag under the weight of enticing tomes devoted to the subject. We are bombarded with advertisements for any one of thousands of different products, both prescription and over-the-counter, that claim to be able to restore our youthful appearance, banish wrinkles, tone skin, and remove cellulite, among other promises that often sound, and probably are, too good to be true. Health food stores and sales catalogs are replete with myriad products, so that one wonders how the average person, in face of such bombardment, can either resist the temptation to buy or make an informed selection from the veritable feast of goodies put before them. Billions of dollars are expended each year, and false claims abound, but fortunately, there are many preparations and procedures that, in skilled hands, can really make a difference.

Beauty↗

Media-portrayed idealized images, self-objectification, and eating behavior.

This study examined the effects of media-portrayed idealized images on young women's eating behavior. The study compared the effects for high and low self-objectifiers. 72 female university students participated in this experiment. Six magazine advertisements featuring idealized female models were used as the experimental stimuli, and the same six advertisements with the idealized body digitally removed became the control stimuli. Eating behavior was examined using a classic taste test that involved both sweet and savory food. Participants' restraint status was assessed. We found that total food intake after exposure was the same in the body present and absent conditions. There were also no differences between high and low self-objectifiers' total food intake. However, for the total amount of food consumed and for sweet food there were significant group by condition interaction effects. High self-objectifiers ate more food in the body present than the body absent condition. In contrast, low self-objectifiers ate more food in the body absent than in the body present condition. Restraint status was not found to moderate the relationship between exposure to idealized images the amount of food consumed. Our results indicate that exposure to media-portrayed idealized images can lead to changes in eating behavior and highlight the complexity of the association between idealized image exposure and eating behavior. These results are discussed in terms of their implications for the prevention of dieting-related disorders.

Adolescent↗

Continental drift under the Third Reich.

Contrary to what happened in many other countries in the 1930s and 1940s, Alfred Wegener's theory of continental drift was not generally rejected in Nazi Germany, although several leading German geologists of the time did not accept it. It was actually presented as the modern view of Earth history in books and magazine articles aimed at the general public. Although outlandish geological theories such as Hörbiger's Welteislehre were favoured by some Nazi dignitaries, they were not widely accepted in scientific circles. On the other hand, continental drift received official support under the Third Reich, at a time when it was ignored or ridiculed by most earth scientists outside Germany.

Biological Evolution↗

"A finer and fairer future": commodifying wage earners in American pulp science fiction.

Long-neglected by scholars, the pulp science fiction (SF) magazines of the Gernsback era (1926-1937) are due for re-examination. Presumed to be sub-literary stories for boys or, paradoxically, escapist leisure reading for practicing scientists and technicians, the SF from this period is actually neither. It is a powerful resource for understanding the ways ordinary people engaged with the promise and peril of industrial modernity. Published by a passionate entrepreneur seeking fame and fortune, composed by writers paid piecework rates and read by young science and technology enthusiasts aspiring to authentic remunerative work, the earliest pulp SF necessarily provoked inter-class discussions about labor, management, production and consumption.

History, 20th Century↗

Forensic aspects of 40 accidental autoerotic deaths in Northern Germany.

Between 1983 and 2003, 40 accidental autoerotic fatalities have been investigated. in the Institute of Legal Medicine in Hamburg. Only 50% (n=20) were autopsied (13 legal autopsies, 6 for scientific purposes and 1 for an insurance company). All the victims were males, aged between 13 and 79 years (among them five children and adolescents, the deceased mainly between 20 and 40 years). The paraphiliacs utilized a great range of devices and props as fetishism, sexual aids or pain-stimulating agents, like intimate feminine garments, ropes, chains, bondages, locks, pornographic magazines, condoms, rubber items, and chemical anaesthetics. The cause of death was strangulation in 20 cases (17 x hanging, 3 x ligature strangulation), 11 x suffocation (8 x under plastic bags, 3 x with face-masks, 2 x thoracic compression, 1 x positional asphyxia, and 1 x cocaine intoxication). Five cases without autopsy remained unclear because of missing morphological and toxicological findings; it could not be differentiated between asphyxiation/intoxication/natural disease, although the scene characteristics seemed to be typical for autoerotic deaths. It is emphasized that the findings at the scene, the morphological and toxicological examination of the dead body (full autopsy as prerequisite) by experienced investigators and the personal history of the deceased have to be evaluated very carefully and intensely to reconstruct the accidental fatal autoerotic course accurately and undoubtedly (to exclude the possibility of sexual homicide, neglected killing, or suicide).

Adolescent↗

A media literacy nutrition education curriculum for head start parents about the effects of television advertising on their children's food requests.

OBJECTIVE: To evaluate whether a media literacy nutrition education curriculum about the effects of television advertising on children's food choices influenced the behavior, attitudes, and knowledge of Head Start parents. SUBJECTS: Participants were a convenience sample of 35 parents from Head Start programs. DESIGN: This study used a pretest-posttest, comparison condition-intervention condition design. INTERVENTION: The 35 parents participated in both a four-week food safety curriculum (to serve as an educational placebo, comparison condition) that was followed immediately by a four-week media literacy nutrition education curriculum (intervention condition). MAIN OUTCOME MEASURES: Evaluation measures included parents' understanding of the persuasive techniques of commercials; ability to distinguish between truths and claims in advertising; and outcome expectations, values, self-efficacy, and behaviors in relation to talking about television advertisements with children while co-viewing or in response to purchase requests in the grocery store. STATISTICAL ANALYSES: Paired t tests, analysis of covariance, and chi(2) analyses were used. RESULTS: The media literacy nutrition education intervention curriculum had significant effects in terms of Head Start parents' understanding television advertising (P<.001), attitudes about television advertisements (P<.001), outcome expectations (P<.05), values (P<.01), self-efficacy (P<.001), and TV mediation behaviors (P<.001), and understanding of, and ability to read, food labels (P<.001). CONCLUSIONS/APPLICATIONS: Results suggest that a media literacy nutrition education curriculum can be easily conducted by dietitians. Dietitians can modify the curriculum to teach parents how to critically analyze many other forms of media (supermarket magazines, brochures, newspapers, Web sites) that sell nutrition misinformation to the public.

Adult↗

Factors associated with soft drink consumption in school-aged children.

OBJECTIVE: To identify factors associated with nonalcoholic carbonated beverage (soft drink) consumption in children. DESIGN: Mail-in surveys collected by Dragonfly, a children's educational magazine distributed nationally to elementary and middle schools, were analyzed. The survey included questions about frequency of soft drink consumption and factors related to soft drink consumption. SUBJECTS AND PARTICIPANTS: The sample consisted of 560 children, 8 to 13 years old, who completed and mailed in the survey. There was an equal distribution of boys and girls (51% and 49%, respectively). STATISTICAL ANALYSES: Frequency distributions were calculated and chi(2) tests were conducted to determine whether soft drink consumption and related factors varied by sex and age. Multivariate logistic regression analyses were conducted to examine the association of soft drink consumption with each factor after adjustment for potential confounders. RESULTS: Preference for the taste of soft drinks was the strongest predictor in the analysis, with those who reported the strongest taste preference 4.50 times more likely (95% confidence interval=2.89-7.04) to consume soft drinks five or more times per week than those with a lower taste preference. Youth whose parents regularly drank soft drinks were 2.88 times more likely (95% confidence interval=1.76-4.72) to consume soft drinks five or more times per week compared with those whose parents did not regularly drink soft drinks. CONCLUSIONS: Results suggest that several factors may be associated with soft drink intake in school-aged children, most notably taste preferences, soft drink consumption habits of parents and friends, soft drink availability in the home and school, and television viewing. Additional research is needed to verify these findings in a representative sample of children.

Adolescent↗

Correlates of soy food consumption in women at increased risk for breast cancer.

OBJECTIVES: The objectives of the present study were to examine sociodemographic correlates of soy food consumption among women at increased risk of breast cancer, describe factors influencing soy food consumption or nonconsumption, and identify women's sources of information about soy foods. DESIGN: A cross-sectional, self-report survey was used to assess frequency of and factors influencing soy food consumption. Soy food intake was reported for the past year. SUBJECTS/SETTING: Participants were 452 women with family histories of breast cancer who were enrolled in a cancer risk assessment program. STATISTICAL ANALYSES PERFORMED: Comparisons between consumers and nonconsumers of soy foods were performed using multivariate logistic regression and chi(2) analyses. RESULTS: Thirty-two percent reported soy food consumption. Commonly consumed soy foods were vegetable burgers, tofu, and soymilk. Consumers of soy foods were more likely to have higher levels of education and report eating five or more daily servings of fruits and vegetables. The primary reason for consumption of soy foods was eating a healthful diet, whereas insufficient knowledge about soy food preparation was the primary reason stated for nonconsumption. Both consumers and nonconsumers reported obtaining information about soy foods from magazines, friends, and newspapers. Consumers also indicated using the Internet to seek information. CONCLUSIONS: These findings contribute to our understanding of the level of soy intake among women at increased risk for breast cancer and highlight potential factors that may influence women's decisions regarding soy food consumption. Women, particularly in this vulnerable population, would benefit from clear messages regarding the health effects of soy.

Adult↗

Internet food marketing strategies aimed at children and adolescents: a content analysis of food and beverage brand web sites.

Americans are spending an increasing amount of time using "new media" like the Internet. There has been little research examining food and beverage Web sites' content and marketing practices, especially those that attract children and adolescents. The purpose of this study was to conduct a content analysis of food- and beverage-brand Web sites and the marketing techniques and advertising strategies present on these sites. The top five brands in eight food and beverage categories, 40 brands in total, were selected based on annual sales data from Brandweek magazine's annual "Superbrands" report. Data were collected using a standardized coding form. The results show a wide variety of Internet marketing techniques and advertising strategies targeting children and adolescents. "Advergaming" (games in which the advertised product is part of the game) was present on 63% of the Web sites. Half or more of the Web sites used cartoon characters (50%) or spokescharacters (55%), or had a specially designated children's area (58%) with a direct link from the homepage. With interactive media still in its developmental stage, there is a need to develop safeguards for children. Food and nutrition professionals need to advocate for responsible marketing techniques that will support the health of children.

Adolescent↗

Influences of sex-related information for STD prevention.

PURPOSE: Adolescents obtain information about sex from the media and friends and so on. This study explores the influence and needs of sex-related information from mass media and other resources. METHODS: Thirteen Focus Group Interviews were conducted with 88 high school and university students (46 female/42 male) from August 2001 to February 2002. RESULTS: Friends or seniors are the most important source of information, and adolescents felt much peer pressure by such information while they learned STD prevention and contraception. The participants were aware of the inconsistencies and biases of information they get through the media. They thought women's magazines seriously treated sex as a health issue concerning women, and provided useful information. CONCLUSIONS: Influences the media has on the knowledge and awareness of young people are significant. It is crucial to fill the gap between the intention of the transmitter of information and the needs of the audience so that the media can be better utilized for sexual health promotion.

Adolescent↗

The mass media are an important context for adolescents' sexual behavior.

PURPOSE: This study compared influences from the mass media (television, music, movies, magazines) on adolescents' sexual intentions and behaviors to other socialization contexts, including family, religion, school, and peers. METHODS: A sample of 1011 Black and White adolescents from 14 middle schools in the Southeastern United States completed linked mail surveys about their media use and in-home Audio-CASI interviews about their sexual intentions and behaviors. Analysis of the sexual content in 264 media vehicles used by respondents was also conducted. Exposure to sexual content across media, and perceived support from the media for teen sexual behavior, were the main media influence measures. RESULTS: Media explained 13% of the variance in intentions to initiate sexual intercourse in the near future, and 8-10% of the variance in light and heavy sexual behaviors, which was comparable to other contexts. Media influences also demonstrated significant associations with intentions and behaviors after all other factors were considered. All contextual factors, including media, explained 54% of the variance in sexual intentions and 21-33% of the variance in sexual behaviors. CONCLUSIONS: Adolescents who are exposed to more sexual content in the media, and who perceive greater support from the media for teen sexual behavior, report greater intentions to engage in sexual intercourse and more sexual activity. Mass media are an important context for adolescents' sexual socialization, and media influences should be considered in research and interventions with early adolescents to reduce sexual activity.

Adolescent↗

Assessing quality of life in gastric bypass clients.

Obesity is currently an epidemic in the United States. Gastric bypass surgery has been a topic of increased interest in the last two decades. Some hospitals started intestinal bypass surgeries in the late 1960s. Gastric bypass has been in the media in the last couple of years because certain popular magazines have reported a variety of actresses obtaining resectional gastric bypass (RGB) surgery. However, little long-term research (greater than 5 years) has been done with a view of quality of life issues surrounding gastric bypass. This article explores the long-term effects of obesity and RGB surgery. The barriers to obesity and quality of life are also investigated in this review.

Adolescent↗

Stress influences the level of negative affectivity after forehead cold pressor pain.

The purpose of this study was to investigate simultaneously a stress manipulation and an experimental pain manipulation to determine how stress and pain interact to influence negative affectivity. One hundred healthy subjects completed a counterbalanced repeated measure crossover design in which stress (speech task) versus a nonstress control condition (magazine reading) was manipulated. Each session was immediately followed by a 2-minute forehead cold pressor task. Measures of affectivity (Positive Affect Negative Affect Schedule), pain ratings, cardiovascular measures (systolic blood pressure, diastolic blood pressure, heart rate), and salivary cortisol were obtained during each session. Regression analysis showed that the stress manipulation influenced the level of anger and that change in anger predicted post-pain negative affectivity independently of the contribution of maximum pain (model R(2) =.31), with 45% of the total model variance accounted for by change in anger and 17% of the total model variance accounted for by maximum pain intensity. In the nonstress condition only level of pain intensity was an independent predictor of negative affectivity (model R(2) =.16), with 69% of the total model variance accounted for by maximum pain intensity. These results show that stress significantly amplifies post-pain negative mood beyond that accounted for by the level of pain intensity alone.

Adult↗

The role of dysfunctional beliefs and attitudes in late-life insomnia.

OBJECTIVES: This study examined the role of individual and combined sleep-related dysfunctional beliefs in late-life insomnia. METHODS: Older adults who responded to an advertisement in a magazine took part in a cross-sectional survey (N=382). Respondents completed self-report measures of dysfunctional beliefs about sleep (Dysfunctional Beliefs and Attitudes to Sleep Scale) as well as measures of their current sleep patterns. RESULTS: Overall, people with insomnia (PWI) endorsed more extreme ratings of dysfunctional beliefs than "good sleepers" did. However, some sleep-related dysfunctional beliefs did not discriminate PWIs from good sleepers nor were they related to experiencing a longer duration of insomnia. CONCLUSION: This article demonstrates that not all sleep-related dysfunctional beliefs are related to reporting insomnia and that some are not related to a longer reported duration of insomnia, possibly changing through personal experience. These preliminary results may have implications for tailoring the cognitive aspects of psychoeducational programmes for people with late-life insomnia.

Aged↗

Changes in women's attitudes towards and use of hormone therapy after HERS and WHI.

OBJECTIVES: To assess changes in women's attitudes towards risk and benefits of, and use of hormone treatment in the menopausal transition (HT) before and after Heart and Estrogen/Progestin Replacement Study (HERS) and the oestrogen and progestin trial of Women's Health Initiative (WHI). METHODS: Postal questionnaires to all women 53 and 54 years of age in a Swedish community in 1999 (n=1.760) and 2003 (n=1.733). Data on sales of HT were collected from the database of the National Corporation of Swedish Pharmacies. RESULTS: The fraction of women reporting current use of HT fell from 40.5 to 25.3% (p<0.001, chi2-test) both by fewer women starting and more women discontinuing treatment. This corresponded to a decrease in dispensation of HT in Linköping and nationwide for the same age group. The fraction of women who had tried complementary treatment for climacteric discomfort, increased from 9.6 to 18.1% for natural remedies (p<0.001, chi2-test). Women perceived HT as more risky and less beneficial in 2003 as compared with 1999 (both p<0.001, chi2-test). The most frequent source of information about HT during the last year before the 2003 questionnaire were newspaper or magazines (43.8%) and television or radio (31.7%). CONCLUSIONS: The decreased use of HT in the community correlated with pronounced changes in the attitudes towards HT. Media were a more frequent source of information than health care personnel. This indicates that media reports about major clinical studies might have influenced the use of HT among women.

Communications Media↗

Women's behaviour, beliefs and information sources about physical exercise in pregnancy.

OBJECTIVE: To examine the potential effect of low-risk pregnancy on women's recreational activity patterns and to explore pregnant women's beliefs and information sources regarding physical exercise participation. DESIGN: Preliminary, prospective survey SETTING: Participants' homes in the East Midlands, UK. PARTICIPANTS: Fifty-seven nulliparous, pregnant women. MEASUREMENTS: Levels of maternal physical activity participation were assessed by semi-structured interview at 16, 25, 34 and 38 weeks gestation. The modified Baecke questionnaire provided a measure of women's habitual sport and leisure activities in the 12 months prior to pregnancy. A 10-item scale assessed maternal beliefs regarding the importance of physical activity in pregnancy. The fetal health locus of control scale measured the extent to which women believed their own behaviour, the behaviour of others and/or chance would influence fetal health. Open-ended questions assessed women's information sources. FINDINGS: Fourteen of the 36 (39%) women who reported participating in some form of weekly exercise before pregnancy did not report pursuing any similar activities during pregnancy. Rest and relaxation were perceived as being significantly more important during pregnancy than was regular exercise or the maintenance of an active lifestyle. Fifty-five respondents (96%) indicated that they had received advice about physical activity at least once during pregnancy. At 16 weeks gestation, women obtained most of their information from books and magazines. Between 25 and 38 weeks gestation, most advice came from family and friends. Participants who reported receiving this advice were significantly older, more educated and of a higher activity level pre-pregnancy. KEY CONCLUSIONS: Levels of maternal exercise may decline during pregnancy both as a result of the physical changes of pregnancy and from a combination of social and psychological factors. Present health education may be failing to correct inaccurate perceptions of the risks associated with physical exercise in pregnancy. IMPLICATIONS FOR PRACTICE: Improving the quantity and quality of information related to physical exercise has the potential to correct inaccurate perceptions and confer several benefits on maternal and fetal health. Effective intervention strategies should focus not only on the pregnant woman but also extend to her family, friends and exercise provider.

Adaptation, Psychological↗