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[Lymphography in childhood (author's transl)].

Fifty-one lymphograms were performed in children; the indications, technique and results are discussed. Indications are the search for retroperitoneal involvement in lymphogranulomatosis, lympho-sarcoma and reticulum cell sarcoma; in the search for metastases from malignant tumours, particularly abdominal neuroblastoma, soft tissue sarcomas of the abdomen and lower extremities, testicular tumours and malignant melanomas and finally, for primary lymph-oedema and lymphangiomas. Technique is the same as for adults, but requires particular manual dexterity. Children under six years require general anaesthesia. Amongst 28 children with malignant lymphomas, pathological changes in the retroperitoneal lymph nodes were found in seven. In six, this resulted in a change of the staging. Five out of 16 lymphograms in children with malignant tumours showed evidence of lymph node metastases. All six lymphangiograms in children with lymphoedema and lymphangiomas were abnormal.

Abdominal Neoplasms↗

[Indirect lymphography of the retrosternal lymphatics and of the thoracic duct (author's transl)].

Successful demonstration of the retrosternal lymphatics and of the thoracic duct after infradiaphragmatic injection is reported, using a contrast medium developed by the author. The lymphatics opacify after 45 minutes. After fourteen days the substance can no longer be seen radiogically. Following some preliminary investigations, it is proposed to try the method in humans. The importance of the lymphatic pathways in medial carcinomas of the breast and in the movement of carcinoma cells from the peritoneal cavity and the liver is stressed.

Animals↗

[In-flow of contrast into the liver--a rare complication during lymphography (author's transl)].

A lymphogram is described in which Lipiodol was found to have reached the liver from pelvic lymphatics. The common iliac and para-aortic lymph nodes had been invaded by tumour from a squamous carcinoma and this had produced complete lymphatic obstruction of the normal lymph paths. In addition, there was occlusion of the bifurcation of the iliac veins due to tumour, a finding also described by other authors. The causes for the finding of Lipiodol in the liver are discussed. The pathway by which the Lipiodol had reached the liver from the pelvic lymphatics, and the reaction of the liver parenchyma to the contrast medium, are considered.

Adult↗

Endoscopic indirect lymphography in gastric cancer.

An oil-in-water emulsion containing 55% Lipiodol, 5% Tween 80 and 40% Angiografin was injected into stomach walls at 20 points to visualize the regional lymph nodes. At each point 0.5 ml emulsion was injected into the submucosal layer. Conventional X-ray pictures of the upper left abdomen were taken at the 24th, 48th, and 72nd hours and on the day before surgery. The method was employed in 18 stomach cancer patients and 5 healthy controls. X-ray findings were verified during the operation and by histological sections stained with hematoxylin eosin, Sudan III and Sudan black. It was established that almost all lymph nodes were visualized, and the lymphograms showed no changes in the healthy stomach. In stomach carcinoma cases metastatic signs were node enlargement, vacuolization with central and/or peripheral filling defects or absence of contrast in nodes. The possibility of applying the method for regional preoperative chemotherapy in early carcinoma stages is discussed.

Contrast Media↗