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Dental manifestations of inbreeding.

This study evaluated the prevalence of genetic dental defects of children within different levels of inbreeding in Borj Salhi, Tunisia. One hundred and twenty one children six to nineteen years old were studied. Results were compared to Tunisian Pediatric Dentistry Society report. The findings showed high prevalence of dental structure anomalies (16%) and malocclusions (28%). It was concluded that genetic factors are responsible for a statistically significant portion of the dental anomalies.

Adolescent↗

[The meadow Mari: inbreeding and endogamy].

The genetic structure of Lugovye Maris was studied on the basis of marital migration. Malecot's parameters of isolation and endogamy index were estimated in four rations of the Marii El Republic, which is populated by Maris. High values of the endogamy index (0.80 and 0.88) never observed previously in any Russian populations, were revealed in two rations. The lack of significant correlation between endogamy and local inbreeding was analyzed. A significant correlation (0.70) between endogamy and effective population size was revealed.

Consanguinity↗

Bootstrap tests for specific hypotheses at single locus inbreeding coefficients.

Deviations of genotype distribution from Hardy-Weinberg expectations within a (sub)population can give valuable insight into the population structure, and can be quantified by means of F(is) values. Specific biological and/or genetical hypotheses regarding F(is) require particular statistical procedures to be able to perform the test with high power. The bootstrap offers a convenient way to test against a broad range of alternative hypotheses. It enables: a) comparison of an observed F(is) with any expected value between -1 and 1, and b) comparison of two or more observed F(is) values. However, it fails under numerous situations, and great caution should be taken before applying the bootstrap to estimate confidence intervals of F(is). We discuss under which conditions the bootstrap gives reliable results.

Gene Frequency↗