Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Heart Block”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 649 records · Page 36Linked to original sources
PubMed1994

Complete heart block in an adult with systemic lupus erythematosus.

Report of a case of complete heart block in a patient with systemic lupus erythematosus (SLE). The cardiac disturbance presented as repeated syncopal episodes and normal cardiac clinical and electrocardiographic examination between these episodes. Circulating anti-U1RNP antibodies were detected and tests for anti-SSA/Ro, anti-SSB/La and antiphospholipid antibodies were negative. Evidence of myocarditis was not found. The diagnosis was just established when the patient developed a syncopal episode during hospitalization. Only one SLE case with a similar clinical course has been reported previously.

Adult↗
PubMedDate not supplied

Heart block and sudden death associated with fibrosis of the conduction system at the margin of a ventricular septal defect.

Isolated ventricular septal defects in clinically well patients are not generally thought to cause sudden death. We document a case in which heart block, with sudden collapse and death, is related to the presence of fibrous interruption of the conduction system of the heart due to progressive fibrous closure of a small ventricular septal defect.

Fatal Outcome↗
PubMed2001

Significance of early transient complete heart block as a predictor of sudden death late after operative correction of tetralogy of Fallot.

We evaluated the long-term outcome and incidence of sudden death in the 288 patients discharged after corrective operation for tetralogy of Fallot at the University of Minnesota between 1954 and 1974. The perioperative characteristics of these patients were evaluated with respect to their long-term outcome. A health status survey was sent to each survivor and their functional status was evaluated with respect to the perioperative variables. Current follow-up was available in 279 of 288 of the postoperative survivors (97%); the mean duration of follow-up was 28 years. The 40-year survival rate was 76% and 154 of 163 of survey responders (95%) were in New York Heart Association class I or II. Twenty-six of the 288 died suddenly (9%). Those with transient complete heart block that persisted beyond the third postoperative day had a lower long-term survival rate (p <0.001) and a higher incidence of late sudden death (p <0.001). Patients aged >12 years at operation had a lower long-term survival rate (p <0.001) and less favorable long-term functional status. The use of a transannular patch was associated with increased late morbidity but not mortality. Thus, the very long-term outcome after operative correction of tetralogy of Fallot is excellent. Late sudden death remains a concern for operative survivors, occurring in 9% of these patients. Late sudden death is strongly associated with transient complete heart block that persisted beyond the third postoperative day.

Adolescent↗
PubMed1998

Chronotropic competence of the sinus node in congenital complete heart block.

Electrocardiograms taken at rest of 2 children with transplacental exposure to anti-Ro antibody but 1:1 atrioventricular conduction demonstrated sinus node disease. Treadmill exercise testing of 28 patients with congenital complete heart block found 3 patients with chronotropic incompetence of the sinus node.

Adolescent↗
PubMed2001

Acute myocardial infarction complicated by heart block in the elderly: prevalence and outcomes.

BACKGROUND: Although second- and third-degree heart block (HB) are common conduction disorders associated with acute myocardial infarction (MI), patient characteristics and HBs association with outcomes, particularly among the elderly, remain poorly defined. METHODS: We evaluated 106,780 Medicare beneficiaries aged 65 years and older treated for acute MI between January 1994 and February 1996 for development of HB. HB and non-HB patients were compared by univariate analysis, and the influence of HB on outcomes was evaluated by unadjusted and multiple logistic regression. RESULTS: HB was documented in 5048 (4.7%) patients; 1646 presented with HB and 3402 developed HB during hospitalization. HB was more common among patients with inferior infarctions than anterior infarctions (7.3% vs 3.0%, P =.001), particularly the cohort of patients with inferior MI treated with reperfusion therapy (8.3%). HB patients had higher rates of in-hospital mortality (29.6% vs. 17.5% vs. non-HB patients, P =.001). After adjustment for demographic and clinical factors, HB remained an independent predictor of in-hospital mortality (relative risk [RR] 1.41, 95% confidence interval [CI] 1. 34-1.48), but HB had no prognostic significance at 1 year among hospital survivors (RR 0.94, 95% CI 0.88-1.01). Mortality risks varied on the basis of MI location. Both anterior MI (RR 1.46, 95% CI 1.30-1.63) and inferior MI (RR 1.52, 95% CI 1.39-1.66) patients with HB had increased risks of in-hospital mortality. There was a trend toward increased mortality among patients with anterior MI (RR 1.15, 95% CI 0.99-1.32) at 1 year, whereas those with inferior MI were at lower risk (RR 0.83, 95% CI 0.75-0.98). CONCLUSIONS: HB is a common complication of acute MI in elderly patients, particularly among patients with inferior MIs who received reperfusion therapy. HB is independently associated with short-term but not long-term mortality.

Age Factors↗
PubMed1999

[Arrhythmias and heart blocks in flying personnel with mitral valve prolapses].

Investigated were 76 pilots with ECG-verified mitral valve prolapses (MVP) of the 1st and 2nd degree (w/o profound regurgitation). There were various heart blocks and ECG repolarization changes in 35 cases. Comparison of results of the cardiovascular functional investigations of flyers with MVP displayed non-specific cardiac rhythm and conductance disturbances that were registered more often during ECG-monitoring or test loading. According to the data of this study, bicycle and treadmill ergometry revealed "pseudoischemic" shifts in ECG. Literary indications of a significant loss in human endurance of physical loads due to MVP combined with the strain-induced arrhythmia received the experimental confirmation. Probably, arrhythmias in flyers with diagnosed MVP are predominantly associated with electric instability of the myocardium against the autonomous dysfunction with prevailing adrenergic effects.

Adult↗
PubMed1984

Exercise induced ventricular ectopics in patients with isolated congenital complete heart block and their association with inadequate chronotropy.

Treadmill exercise tests preformed on 13 patients with isolated congenital complete heart block are described. Premature ventricular contractions appeared with exercise in 5/13 patients. The 5 patients who developed ventricular ectopics with exercise had lesser increments in their junctional rates with exercise as compared to the remaining patients (P less than .025). Two of these 5 patients subsequently experienced syncope and required pacemaker insertion. The two groups of patients were indistinguishable in terms of age, sex, resting heart rates, presence or absence of cardiomegaly. The site of AV block appeared to be above the bundle of His in all instances (proven in 9/13). It is suggested that the association between ventricular ectopic activity and inadequate chronotropy with exercise could have a pathophysiological link and might indicate an unfavorable prognosis.

Adolescent↗
PubMed1995

Comparison of dual chamber and ventricular rate responsive pacing in patients over 75 with complete heart block.

OBJECTIVE: To compare symptoms and exercise tolerance during dual chamber universal (DDD) and ventricular rate response (VVIR) pacing in elderly (> or = 75) patients. DESIGN: Randomised, double blind, crossover study. SETTING: Regional cardiac department. PATIENTS: Twenty elderly patients (mean age 80.5 (1) years) with high grade atrioventricular block and sinus rhythm. Patients with pre-existing risk factors for the pacemaker syndrome and chronotropic incompetence were excluded. INTERVENTION: After four weeks of VVI pacing following pacemaker implantation, patients underwent consecutive two week periods of VVIR and DDD pacing. MAIN OUTCOME MEASURES: Patient preference, symptom scores, "daily activity exercises," and perceived level of exercise (Borg score). RESULTS: Eleven patients preferred DDD mode to either VVI or VVIR mode. Mean (SE) total symptom scores during VVI, VVIR, and DDD pacing were 5.9 (1.1), 6.1 (1.0), and 3.5 (0.9) respectively (P < 0.01). The corresponding mean (SE) pacemaker syndrome symptom scores were 4.8 (0.7), 5.2 (0.8), and 2.9 (0.8) (P < 0.05). Symptom scores during VVI and VVIR pacing were not significantly different. Exercise performance and Borg scores were significantly worse during VVI pacing compared with VVIR or DDD pacing but did not significantly differ between VVIR and DDD modes. CONCLUSIONS: In active elderly patients with complete heart block both DDD and VVIR pacing are associated with improved exercise performance compared with fixed rate VVI pacing. The convenience and reduced cost of VVIR systems, however, may be offset by a higher incidence of the pacemaker syndrome. In elderly patients with complete heart block VVIR pacing results in suboptimal symptomatic benefit and should not be used instead of DDD pacing.

Aged↗
PubMed1985

Congenital complete heart block.

Recent studies have demonstrated immunologic abnormalities in the mothers of infants with congenital complete heart block. The disorder should be suspected when a slow pulse rate is detected before or after birth. The block most often occurs in the AV node. There are several specific indications for pacemaker therapy. Most patients who survive beyond infancy are able to lead relatively normal lives.

Heart Block↗