Disorders of eye movements.
Eye movements serve the needs of our visual sense and can be classified into subtypes according to their specific functions. Main functions and dysfunctions are given, with an emphasis on nystagmus.
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Eye movements serve the needs of our visual sense and can be classified into subtypes according to their specific functions. Main functions and dysfunctions are given, with an emphasis on nystagmus.
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Orthophorization is a slow mechanism that compensates disturbances in the binocular eye position. Normal binocular vision is a prerequisite. Because of orthophorization patients who have undergone a Kestenbaum operation for ocular torticollis remain orthophoric postoperatively.
We measured the roles of eye muscle proprioception ("inflow") and efference copy ("outflow") in registering eye position. During monocular fixation, pressing on the side of an occluded eye results in a passive rotation, changing the proprioception without affecting oculomotor efference. As we have shown previously, a constant press on the side of the viewing eye induces active resistance to rotation, changing efference because oculomotor innervation compensates for the eyepress; the viewing eye's fixation remains constant. Using these two types of eyepress, both perceived target deviations and pointing biases in an unstructured visual field were measured in 8 subjects under efference copy, proprioception and control (no eyepress) conditions. Eye deviation was measured photoelectrically. Physiological gains of efference copy and proprioception was about 5/8 and 1/4 respectively. There was no statistically significant difference between perceptual judgement and open-loop pointing. The sum of gains of efference copy and proprioception, about 7/8, indicates incomplete registration of eye eccentricity in an unstructured field, and quantitatively accounts for several previously unexplained results in the literature.
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The relationship between the neural processing of color and motion information has been a contentious issue in visual neuroscience. We examined this relationship directly by measuring neural responses to isoluminant S cone signals in extrastriate area MT of the macaque monkey. S cone stimuli produced robust, direction-selective responses at most recording sites, indicating that color signals are present in MT. While these responses were unequivocal, S cone contrast sensitivity was, on average, 1.0-1.3 log units lower than luminance contrast sensitivity. The presence of S cone responses and the relative sensitivity of MT neurons to S cone and luminance signals agree with functional magnetic resonance imaging (fMRI) measurements in human MT+. The results are consistent with the hypothesis that color signals in MT influence behavior in speed judgment tasks.
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BACKGROUND: Young chicks can adjust their eye growth to compensate for both imposed hyperopia and myopia (using negative and positive spectacle lenses); the rate of eye elongation increases in the former and slows in the latter case. This emmetropizing behavior implies that the eye can distinguish the sign and magnitude of defocus, although the identity of the cue(s) involved is unknown. As the spectacle lenses used in these studies generally introduce significant retinal image size differences that are in opposite directions for negative and positive lenses (minification vs. magnification), we asked whether retinal image size might provide the required sign information. METHODS: This question was addressed by manipulating retinal image size while keeping lens power constant. We also investigated the effect of eliminating other potential cues, accommodation and chromatic aberration, under these conditions. Three negative "size" lenses of approximately -11 D optical power were used, with 2 of the lenses producing magnification rather than minification as typical of negative lenses (i.e. +1.9% and +6.9% compared to -2.9%). The lenses were fitted monocularly to 7-day-old chicks, which were subsequently measured at 9 and 11 days of age (refractive error and axial dimensions). The same lens-wearing schedule was applied to two other groups of chicks that had monocular ciliary nerve section surgery to prevent accommodation 2 days posthatching; one of these groups was reared under monochromatic yellow light instead of white light. RESULTS: Near-perfect refractive compensation was seen by the end of the treatment period with all three lenses, for all three treatment groups, and there was also little difference in the rate of compensation among the various groups. In all cases, the typical responses of axial (mainly vitreous chamber) elongation and myopia were observed. CONCLUSIONS: That manipulations to retinal image size, which either decrease or reverse the usual effects of negative lenses, did not disrupt compensation to the imposed hyperopic defocus, even in the absence of accommodation and chromatic aberration cues, argues against imposed retinal image size changes being the directional cue to defocus in experimental emmetropization.
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