Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “DIAZOXIDE”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 649 records · Page 36Linked to original sources

[Changes in heart function during the use of the peripheral vasodilator diazoxide on arterial hypertension patients].

An acute depression of arterial blood pressure (ABP) was achieved using intravenous injections of 300 mg diasoxide in 29 patients with persistent arterial hypertension. Peripheral vascular resistance dropped significantly, and the minute volume slightly increased at the point of the deepest ABP fall. Intracardiac hemodynamics showed no significant changes. Myocardial contractility, as determined by dp/dtmax and ABP d/IC, increased in the presence of a relatively small ABP decrease (by 20-25% of the original values), and decreased when ABP dropped by 30% or more. These changes may be related to reduced coronary flow where ABP fall is significant.

Diazoxide↗