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At least 649 records · Page 36Linked to original sources
PubMed1989

Effects of hypertonic NaCl solution on the hamster cheek pouch microcirculation in normo- and hypovolemia.

The aim of this study was to evaluate the effects of a single, 10 min, intravenous infusion of a hypertonic NaCl solution [2400 mOsm/l; infused volume 0.35 +/- 0.03 ml (SEM)] on the hamster cheek pouch microcirculation during normovolemia and after acute bleeding to a hypotension level of about 40 mmHg. Upon bleeding, the arterial pressure dropped to 39 mu 1 mmHg, arterioles greater than 40 microns constricted 12 +/- 3% (from their control value), arterioles less than 40 microns dilated 6 +/- 2%, venules stayed largely unchanged, while RBC velocity and volume flow decreased 57 +/- 7% in all vessels. During the subsequent hypertonic NaCl infusion, the arterial pressure increased rapidly to a new steady state level of 66 +/- 3 mmHg. After the infusion, the large arterioles stayed constricted 11 +/- 1% and the small arterioles dilated 7 +/- 1% for a 1-h observation period. The venules constricted initially by 6 +/- 2% and returned to control diameter in 30-40 min. RBC velocity and calculated volume flow returned to the pre-hemorrhage control values in about 10 min for the arterioles and in 40 min for the venules. An identical hypertonic infusion given to normovolemic hamsters caused no significant alterations of the measured variables.

Animals↗
PubMed1989

Cancer of the cheek.

The combined skills of the micrographic surgeon and the head and neck surgeon offer excellent cure rates and reconstructive techniques for primary cutaneous tumors of the cheek. In most instances, structures crucial to facial function and appearance can be preserved or rehabilitated. This interspecialty approach to such tumors results in the best care for the patient and a high sense of professional satisfaction for the surgical team.

Cheek↗
PubMed1978

[Closure of extensive oroantal perforations, caused by extraction, by means of modified gingival cheek flaps].

The reliable Rehrmann method of pedicaled buccal flaps taken from the gums and cheeks accompanied by slitting of the periosteum does not provide sufficiently long flaps for the wide junction betueen the oral cavity and the maxillary sinus which extends toward the palate. A sliding flap is recommended in such cases. This flap is formed by a triangle-shaped excision combined with cranial and caudal slitting of the periosteum. This procedure can also be used for simultaneous operations on the maxillary sinus after the bony defect has been closed with the method of bony coverage developed by the author.

Cheek↗
PubMed1988

Possible changes in the leukocyte membrane as a mechanism of leukocyte adhesion to the venular walls induced by leukotriene B4 and fMLP in the microvasculature of the hamster cheek pouch.

Images of the microvasculature of the hamster cheek pouch were projected on TV monitor screen using a monochrome TV camera. Rolling and adhesion of the polymorphonuclear leukocytes on the venular wall were continuously recorded by a newly developed videodensitometer, as changes in average intensity of videosignals in a given detection window superimposed on the screen. Topical application (2.5, 5 and 10 nmol/50 microliter) of fMLP (formyl-methionyl-leucyl-phenylalanine) or superfusion of leukotriene (LT) B4 (0.3, 3 and 30 pmol/ml/min) caused dose-dependent increase in the number of leukocytes adhering to the venules, but a tendency of rolling leukocyte to decrease. Local pretreatment of the microvasculature with a selective 5-lipoxygenase inhibitor (AA-1777) prevented the leukocyte adhesion induced by fMLP (10 nmol/50 microliter), indicating that this adhesion was induced through generation of 5-lipoxygenase products. Selective injection of fMLP (10, 30 and 100 pmol/0.1 microliter) by micropipette into the connective tissue close to the capillary dose-dependently increased the number of leukocytes adhering to the venule downstream, but injection of the highest dose (100 pmol/0.1 microliter) close to the venular wall caused no adhesion to the same venule. Similar results were obtained with LTB4 (30 fmol/0.1 microliter). These findings suggest that fMLP or LTB4 applied topically is absorbed from the capillaries and induces membrane changes in the leukocytes, but not in the endothelial cells, resulting in their adhesion to the venular wall.

Animals↗
PubMed1979

False aneurysm of the cheek: report of two cases.

Two cases of false aneurysm that occurred in the cheek are described. The clinical and histological findings indicated the lesions were due to hemorrhage caused by blunt and iatrogenic trauma. In addition, a continuous supply of blood into the cystic spaces through small veins or dilated capillaries in the wall was possibly a contributing factor to their pathogenesis. The lesions were successfully treated by surgical excision.

Aneurysm↗
PubMed1988

Involvement of palate and cheek in leprosy.

22 Cases of bacillary positive leprosy with no apparent lesion in the oral cavity, soft or hard palate were studied for any evidence of pathological involvement. Granulomata were present in 11 (65%) out of 17 cheek biopsies studied. M. leprae were identified in four specimens only. 9 specimens (64%) out of 14 palate biopsies showed definite granulomata. M. leprae were seen in six specimens.

Adolescent↗
PubMed1988

Repair of avulsion of eyelids and cheek.

Our patient was thrown through the roof of a soft-top Jeep. The right upper and lower lids and the cheek were separated completely from their attaching structures and were hinged laterally over the zygomatic arch. The patient had normal extraocular rotations but could not see when the face flap was replaced. Steps in repair of these separated structures are described. A satisfactory cosmetic and functional result was achieved by anatomic reconstruction. Ptosis surgery at a later date was necessary to give a more normal appearance.

Adult↗
PubMedDate not supplied

Results of immediate reconstruction following surgery for advanced cases of cancer of the cheek, jaw and lip.

Results of immediate reconstruction of the defects resulting from excision of cancer of the cheek, lower jaw, upper jaw and lip in 13 patients using temporal island, deltopectoral and cervicoacromial flaps have been described. The surgical techniques have been outlined. Previous radiotherapy is not a contraindication for primary excisional and reconstructive procedures although the incidence of postoperative gangrene of the flap was greater in these cases.

Adult↗
PubMedDate not supplied

[Seasonal changes in the adrenergic fibers in the wall of the microvessels of the cheek pouch of the hamster, Mesocricetus auratus].

Adrenergic innervation has been investigated by fluorescent histochemical method with glyoxylic acid. Adrenergic fibers were found in summer period on the arterioles with a diameter varying from 100 to 30 micron, their fluorescence being significantly lower than that in the vessels of microcirculatory bed of the mesentery, tongue, femoral muscles of the same animal. No adrenergic fibers were revealed on the arterioles with a smaller diameter, on veins and venules. In winter period, fluorescence is completely absent from all the vessels of the cheek pouch, which may be due to the decrease in the level of catecholamines in the nerves and other tissues during hibernation.

Adrenergic Fibers↗
PubMed1986

Antithrombotic effects of sodium salt of 17(R)-methyl-20-isopropylidenecarbacyclin in the arteriole of the hamster cheek pouch.

Antithrombotic effects of sodium salt of 17(R)-methyl-20-isopropylidenecarbacyclin (CS-570), a chemically stable prostaglandin I2 (PGI2, epoprostenol, prostacyclin) derivative, were investigated in the arteriole of the hamster cheek pouch. A microthrombus was produced by a slight mechanical injury followed by iontophoretic application of adenosine diphosphate (ADP) to an arteriole of 70 to 100 micron in diameter. The platelet thrombus size was determined with a video image processor. With this technique, a reproducible and quantitatively measurable periodical thrombus was obtained. CS-570 inhibited the thrombus formation dose-dependently. The potency of CS-570 was about 1/8 that of PGI2 and 6 times that of carbacyclin when infused i.v. CS-570 also decomposed an established thrombus. Alprostadil (PGE1), dipyridamole and ticlopidine failed to show inhibitory effects. The antithrombotic effect of CS-570 was definitely demonstrated.

Adenosine Diphosphate↗
PubMed1987

Reconstruction of full-thickness cheek defects after cancer surgery.

The value of various surgical techniques used to reconstruct full-thickness cheek defects is discussed. Small defects can be repaired with the use of local cervical skin flaps with a random vascular pattern. Axial pattern temporal flap is another choice, either alone or combined with a cervical flap. Whenever local tissues are not suitable (i.e. after irradiation or neck dissection) a transfer of distant myocutaneous island flap based on a pedicle of axial muscle vessels is a valuable alternative. Split skin graft may form a good intra-oral lining of such island flap.

Aged↗
PubMed1987

[Microsurgical reconstruction of large 3-layer defects of the cheek].

For reconstruction of large penetrating defects of the cheek besides pedicled tissue transfer numerous free flaps are available to the head and neck surgeon. The inferior epigastric abdominal wall flap, in particular, has proved a versatile and reliable flap, just as the cutaneous flaps from the dorsum of the foot and from the forearm. While the abdominal wall flap offers both, a cutaneous and a peritoneal surface, the latter is used for replacement of intra-oral lining, the cutaneous flaps have to be folded to obtain two surfaces for reconstruction of skin and intra-oral lining. The surgical technique of the epigastric abdominal wall flap is presented and its use is discussed.

Carotid Artery, External↗
PubMed1979

[Use of a rotation flap from tissues of the preauricular region and lateral surface of the neck for closing a penetrating defect of the cheek].

The authors use the rotational flap tranfered from the lateral surface of the neck, with one-stage epithelization of the wound surface from the side of the mouth cavity with a split skin graft, to correct the postoperative penetrating defect of the cheek. The necessity of a thorough fixation of the skin graft on the wound surface emphasized.

Cheek↗
PubMed1986

The effects of Candida albicans on turpentine-induced hyperplasia of hamster cheek pouch epithelium.

This investigation aimed to determine the effect of Candida albicans on hyperplastic epithelium. Epithelial hyperplasia was induced in hamster cheek pouches by painting the mucosa with 50% (v/v) turpentine and liquid paraffin (TLP50) for 10 weeks. The pouches were then tied off with sutures after inoculation with C. albicans. Many of the pouches lost their sutures and were histologically normal after periods up to 8 weeks. Those which remained tied off showed epithelial dysplasia resembling changes seen in human candida leukoplakia. It is suggested from these preliminary experiments that C. albicans may be capable, in certain conditions, of causing further changes to hyperplastic epithelium resembling those seen in Candida leukoplakia.

Animals↗
PubMed1979

Myiasis presenting as cellulitis of the cheek.

A case of myiasis due to the northern cattle grub (Hypoderma bovis) in a 2 1/2-year-old girl presenting as cellulitis of the cheek and periorbital cellulitis is detailed in this report. A literature review of similar cases reported over the past five years is included.

Cellulitis↗
PubMed1979

The omental sandwich reconstruction for a full-thickness cheek defect.

We present a case in which a large full-thickness cheek defect was successfully repaired in one stage by the "omental sandwich technique." We transferred the omentum as a free flap, anastomosing the middle omental vessels with the end stumps of the gastroepiploic vessels after they had been brought to the neck through a subcutaneous tunnel. Skin grafts were applied then on both sides of the revascularized omentum.

Carcinoma, Squamous Cell↗