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At least 649 records · Page 36Linked to original sources
PubMed2005

Remodeling characteristics of minimally diseased coronary arteries are consistent along the length of the artery.

Using a method that creates anatomically correct, 3-dimensional arterial reconstructions, 55 minimally diseased coronary arteries from 40 patients were studied. Homogenous remodeling characteristics along the entire length of the artery were observed in 48 arteries (87%). In the aggregate, arteries exhibited compensatory expansive remodeling. Individually, the full spectrum of compensatory expansive remodeling (60%), excessive expansive remodeling (21%), and constrictive remodeling (19%) was observed across arteries. Each artery was consistent in its remodeling characteristics from proximal to distal portions of the artery, and the remodeling pattern of each artery was independent within the same patient.

Adult↗
PubMed1991

Comparison of serial quantitative evaluation of calcified coronary artery plaque by ultrafast computed tomography in persons with and without obstructive coronary artery disease.

Coronary artery calcium indicates atherosclerosis. Ultrafast computed tomography (CT) can noninvasively visualize and quantify coronary calcium, permitting the natural history of calcified plaque to be studied. This pilot study evaluates the ability of ultrafast CT to follow the progression of calcified plaque within the coronary arteries in patients with and without obstructive coronary artery disease (CAD). Twenty-five subjects had serial ultrafast CT scans of the coronary arteries a mean of 406 days apart. Changes in the number of calcific deposits, calcified plaque area and volume, calcium density and total calcium score were measured. In the 20 patients with calcium on the first study, there were statistically significant increases in mean peak CT number, total calcified plaque volume, total calcified plaque area and total calcium score (p less than 0.0001 for all). Subjects with proved obstructive CAD (n = 10) on angiography had a 48% increase in calcified plaque volume compared with 22% in asymptomatic subjects (n = 10). Comparison of serial studies showed that smaller calcific deposits often coalesced into single larger calcific deposits. Ninety-eight percent (235 of 241) of deposits identified on the first study were accounted for on the second study. Patients with obstructive CAD had a higher number of new calcific deposits than did those in the asymptomatic group (55 vs 18, p = 0.058). Serial ultrafast CT accurately tracks the progression of coronary artery calcium. It is a useful technique for assessing changes in calcified plaque formation in both asymptomatic subjects and in patients with obstructive CAD. It may be useful for studying the natural history of CAD and the effects of intervention on the course of CAD.

Adult↗
PubMed1999

Diagnosis and treatment of concomitant aortic and coronary disease: a retrospective study and brief review.

Coronary arteriosclerosis seriously complicates the surgical treatment of aortic diseases. The aim of our retrospective study was to determine the incidence of coronary artery disease among our surgical patients in treatment for aortic dissection or aneurysm, and to determine whether coronary intervention before aortic surgery appears to affect outcomes. Between 1 January 1993 and 1 March 1998, our center treated 253 patients for aortic dissection or aneurysm. We examined these cases retrospectively for information on diagnostic and treatment methods, both for the aortic lesions and for concomitant coronary arteriosclerosis. Aortic dissection had been detected in 86 (33.9%) patients and aortic aneurysm in 167 (66.1%). Coronary angiography was performed to search for concomitant coronary artery disease in 29 (33.8%) patients with dissection and in 112 (67.1%) patients with aneurysm; of these, 11 (12. 7%) and 54 (32.3%), respectively, were found to have coronary disease. Among 43 patients with abdominal aortic aneurysm in whom coronary angiography was performed, concomitant coronary disease was detected in 36 (83.7%). Coronary artery bypass surgery was performed in 10 patients who had dissection and in 30 patients who had aneurysm; percutaneous transluminal coronary angioplasty was performed in 7 patients who had aneurysm. Perioperative mortality rates in the dissection and aneurysm groups, overall, were 23.2% and 13.8%, respectively Unfortunately, the prospective, random clinical study that would be necessary to prove the case for or against preoperative coronary angiography among subsets of patients in need of aortic repair would raise ethical questions, given the strength of the information already in our possession, gathered by less formal methods. Our study reinforces existing evidence that preoperative angiography can reduce mortality and morbidity in the elective repair of aortic aneurysm, especially thoracic or abdominal aneurysm. However, angiography should not be performed routinely in cases of aortic dissection and should be withheld in cases of type A dissection.

Adolescent↗
PubMed1988

Coronary artery spasm and its relationship to exercise in patients without severe coronary obstructive disease.

Coronary artery spasm is reported to occur with exercise. In patients without severe coronary atherosclerosis, the evidence for exercise-induced coronary artery spasm is limited. Three patients with positive exercise tests but no severe coronary atherosclerosis are presented. Coronary artery spasm was provoked and verified by angiography in all three, but coronary angiography during exercise failed to demonstrate spasm. The literature is reviewed and the value of a routine protocol for evaluation is discussed.

Adult↗
PubMed2006

Surgical treatment of coronary multivessel disease.

Coronary artery bypass grafting has had a significant impact on the treatment of angina, and has been the 'gold standard' since 1969. Its use and efficacy has been increased by revascularization in cardiac arrest and the use of the internal mammary artery. In parallel, catheter techniques have evolved by means of balloon dilatation and additional stenting. This has effected the referral to surgery despite the development of new arterialization techniques and minimally invasive surgery. As competing techniques, an acceptable equilibrium between surgery and stenting will be found within the next years.

Angioplasty, Balloon, Coronary↗
PubMed1991

[Fibrinolytic therapy in non-coronary diseases].

Utilization of fibrinolytic drugs in non-coronary diseases has been described since 1949, but despite of that, works about that subject are very rare in the literature. In this paper we discuss the cases of three patients that were treated with such compounds for pulmonary embolism, peripheral arterial embolism, and thrombosis in mechanical aortic prosthesis. All patients had excellent in-hospital outcome, and were totally asymptomatic at the discharge time. It is emphasized the clinical symptoms, sometimes unexpected, and the importance of the complementary tests not only in the disease's diagnosis, but also in some decisions that must be taken during the patient's evolution, where they can help us to decide, for example, about the correct moment to stop the thrombolytic infusion. In conclusion, fibrinolytic drugs can be utilized in the management of many affections that otherwise would be treated by emergency surgery.

Adult↗
PubMed1989

[Basic principles of the prevention of cardiovascular diseases in light of knowledge and opinions of the Polish community. II. Knowledge of coronary disease risk factors].

The study was carried out in 1986, by means of two separated questionnaires, each comprising a 1000-person random sample of the whole Polish population aged above 15 years. The interview showed that 54% of men and 28% of women habitually smoked cigarettes, and 6% of men and 4% of women--occasionally. About 85% of men and 80% of women consumed at least 3 meals per day. Dinner was the most frequently consumed meal. Only 30% of respondents informed that they took food regularly. About 65% of the interviewed people informed that they consumed every day white bread, above 90%--potatoes and vegetables and above a half--meat and meat products. Vegetable oils, margarine and fish appeared to be rarely consumed. About 20% of the inquired ones recognized consumption of dark bread, fish, vegetable oils or margarine as favourable from cardiovascular prevention viewpoint.

Adolescent↗
PubMed2003

Graft patency in off-pump and conventional coronary artery bypass grafting for treatment of triple vessel coronary disease.

OBJECTIVE: To compare graft patency in off-pump and conventional coronary artery bypass grafting by using the transit time flow meter in the treatment of triple vessel coronary artery disease. METHODS: Between June 2000 and April 2001, 60 patients with triple vessel coronary artery disease underwent coronary artery bypass grafting. They were divided into two groups: off-pump and conventional coronary artery bypass. All completed grafts were tested intraoperatively using Transit Time Flow Measurement (TTFM). Preoperative and postoperative variables of the two groups were also compared. RESULTS: There were no significant differences in sex, age, weight, acute or remote myocardial infarction, hypertension, diabetes and type of bypass grafts between the two groups. The number of bypass grafts and the assisted respiratory time of the off-pump coronary artery bypass grafting (OPCAB) group were significantly less than those of the conventional coronary artery bypass grafting (CCABG) group. The flow and pulsatile index (PI) of the left anterior descending artery bypass grafts and the right coronary artery bypass grafts were not significantly different between the OPCAB and CCABG groups. The flow of OM in the CCABG group with the multiple anastomosis site of sequential grafts was higher than that in the OPCAB group. Diffused narrow coronary artery bypass grafts in both groups had less flow. CONCLUSION: No significant differences in graft patency were observed in patients with triple vessel coronary artery disease who had undergone OPCAB or CCABG.

Aged↗
PubMed1983

Ventricular ectopy frequency and complexity not altered by exercise training in coronary disease patients.

To assess the effect of exercise training on ventricular ectopy in coronary artery disease patients, 21 patients with coronary disease had 24-hour ambulatory electrocardiograph recordings done at entry into a cardiac rehabilitation program and after 6 months' exercise training. Mean frequency of premature ventricular contractions was not significantly changed, being 9.7 +/- 33.0/h before and 13.2 +/- 94.3/h after training. 9 demonstrated an increased, 9 a decreased, and 3 an unchanged frequency. Lown grade of ventricular ectopy was similarly not consistently changed with training.

Arrhythmias, Cardiac↗
PubMed1990

[Minimal lipid anomalies in a group of men with early coronary disease compared to a control group].

A group of 27 men with early coronary disease (mean age: 52 years) with cholesterol levels below 6.45 mmol/l and triglycerides levels below 2.3 mmol/l, who underwent a coronary angiography, is compared with a control group of 18 men (CG) with normal angiography. The only significant differences between the two groups are: a triglycerides levels slightly higher in the CM group (1.55 + 0.4 mmol/l) vs 1.18 +/- 0.37 mmol/l, p 0.001), a HDL-cholesterol level slightly lower in the CM group (1.08 +/- 0.19 mmol/l vs 1.26 +/- 0.21 mmol/l, p 0.01) and an Apo AI/Apo B ratio slightly lower in the CM group (1.02 +/- 0.24 vs 1.18 +/- 0.17, p 0.005). In the CM group, 21 patients in 27 present a lipid abnormality requiring, according to the European consensus recommendations, the prescription of hygieno-dietetic measures. In the CM group, 10 patients in 18 present a minimal lipid abnormality, also requiring hygieno-dietetic measures. These results are compared with the recommendations of the European consensus.

Coronary Disease↗
PubMed2005

Association of ankle-brachial index with severity of angiographic coronary artery disease in patients with peripheral arterial disease and coronary artery disease.

The ankle-brachial index (ABI) was correlated with the severity of coronary artery disease (CAD) in 273 patients, mean age 71 years, with peripheral arterial disease and angiographically obstructive CAD (> 50% occlusion). Of 155 patients with an ABI < 0.40, 130 (84%) had 3- or 4-vessel CAD, 17 (11%) had 2-vessel CAD and 8 (5%) had 1-vessel CAD. Of 80 patients with an ABI of 0.40-0.69, 37 (46%) had 3- or 4-vessel CAD, 33 (41%) had 2-vessel CAD and 10 (13%) had 1-vessel CAD. Of 38 patients with an ABI of 0.70-0.89, 10 (26%) had 3- or 4-vessel CAD, 16 (42%) had 2-vessel CAD and 12 (32%) had 1-vessel CAD. The lower the ABI, the higher the prevalence of 3- or 4-vessel CAD and the lower the prevalence of 1-vessel CAD.

Adult↗