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Understanding physicians' intention to use a simple infection control measure: wearing gloves.

OBJECTIVE: The aim of this study was to identify the factors that explain the intention of physicians to wear gloves when contact with blood or body fluids was possible. METHODS: A survey was given to a representative sample of physicians (general practitioners, medical specialist, and surgeons of the Canadian province of Québec). A total of 720 physicians completed the self-administered questionnaire. The respondents' intention to wear gloves, psychosocial variables (attitude, perceived social norm, perceived behavioral control, perceived risk of infection, and habit of wearing gloves), and sociodemographic variables were assessed. RESULTS: A substantial proportion of physicians (80%) had strong intentions to wear gloves when contact with blood and body fluids was possible. Logistic regression indicated that the 3 most important factors explaining intention were perceived behavioral norm, attitudes, and perceived behavioral control. Perceived risk of infections, habit of wearing gloves, and being in a younger age category were additional factors related to intention. CONCLUSIONS: Interventions should reinforce the perception that the use of gloves is the norm among medical professionals. These programs also should emphasize the advantages of wearing gloves, counteract the perceived disadvantages of wearing them, and enhance the ability of physicians to circumvent the difficulties of wearing gloves when required.

Adult↗

Examining social-cognitive determinants of intention and physical activity among black and white adolescent girls using structural equation modeling.

Structural equation modeling was used to evaluate components within the theories of reasoned action (TRA), planned behavior (TPB), and self-efficacy (SET) for understanding moderate and vigorous physical activity among 1,797 Black and White adolescent girls. Modest to strong support was provided for components of TPB and SET; weak support was provided for components of TRA. Perceived behavioral control was related to vigorous physical activity. Self-efficacy was related to moderate and vigorous physical activity, and it accounted for the effect of intention on physical activity. The observed relationships were similar between Black and White girls. Self-efficacy and perceived behavioral control are independent influences on physical activity among Black and White adolescent girls and warrant study as potential mediators in physical activity interventions.

Adolescent↗

Antecedents and moderators of behavioral intention: differences between U.S. and Taiwanese students.

The purpose of this study was to investigate the relative influence of attitude toward the act, subjective norm, and perceived behavioral control on consumers' purchase intention when consumers possess different levels of product knowledge (subjective and objective). The magnitude of the influence is compared across two different societies (U.S. and Taiwanese). U.S. (N = 295) and Taiwanese (N = 297) college students participated. The results showed that the relative importance of attitude toward the act, subjective norm, and perceived behavioral control in predicting purchase intention varied across consumers with different levels of product knowledge (subjective or objective) for the U.S. participants. However, the moderating effect of product knowledge was less profound for the Taiwanese participants.

Behavior↗

Special feature: a multifacet circumplex model of personality as a basis for the description and therapy of personality disorders.

A new circumplex model of personality, based upon two higher order personality factors, mental health and behavior control, is presented. This eight-octant model, which also includes the two multifacet dimensions of "social adaptation vs. unrestraint" and "self-actualization vs. inhibition," should not be confused with two other well-known circumplex models: the interpersonal model and the Eysenck model. Mental health, a multifacet construct, is defined as the ability to cope with external and internal demands. Behavior control, also a multifacet construct, is characterized by self-control (norm-, future-, work-, and reason-orientation; orderliness) vs. spontaneity (hedonism, excitement seeking, feeling orientation, liveliness). The theoretical background and facets of these constructs are presented. The model is useful for the description of personality disorders, and etiological hypotheses are formulated from the combination of this model with a circumplex model of interpersonal behavior. Finally, some therapeutic implications of the model are discussed.

Behavior Therapy↗

Pilot's perception in the control of aircraft motions.

For proper manual aircraft control, the pilot has to perceive the motion state of the aircraft. In this perception process both the visual and the vestibular systems play an important role. To understand this perception process and its impact on a pilot's control behavior a descriptive model was developed. The single-channel information-processor model was applied as the basic structure of the final model. Three groups of experiments were performed to refine the model structure and to define the majority of the model parameters. The model has been evaluated by measuring the control behavior in tracking tasks.

Acceleration↗

Triazolam impairs inhibitory control of behavior in humans.

This study tested the effects of the sedative-hypnotic drug triazolam (Halcion) on the ability to inhibit behavior in humans. Thirty adults practiced a stop-signal task that measured their ability to inhibit and activate behavioral responses on a choice reaction time task. Equal numbers of participants (i.e., n = 10) then received either 0.25 mg, 0.125 mg, or 0 mg (placebo) of triazolam under double-blind conditions and performed the task intermittently over a 3-hr period. In accord with the hypothesis, triazolam reduced response inhibitions and increased the time required to inhibit a response. The drug also slowed the activation of responses. The findings contribute to the understanding of the basic behavioral mechanisms by which sedative-hypnotic drugs can produce states of behavioral disinhibition in some individuals.

Adult↗

Risperidone for AIDS-associated dementia: a case series.

OBJECTIVE: To determine the effect of low-dose risperidone on behavioral disturbances associated with AIDS dementia in young-to-middle-age nursing home patients. Neuroleptics are commonly used for behavioral control in this population, but these drugs often fail to control symptoms, and carry a high risk of movement disorders. Because the AIDS virus attacks the basal ganglia, these patients are highly susceptible to neuroleptic-induced movement disorders that increase the risk of falling. However, low-dose risperidone reportedly carries little risk of movement disorders. METHOD: Nine nursing home patients with AIDS dementia received risperidone for behavioral disturbances (psychomotor agitation, aggressiveness, social withdrawal, uncooperativeness) or psychotic symptoms. Seven were switched to risperidone because their symptoms were unresponsive to conventional neuroleptics and adjunct benzodiazepines, antidepressants, or methylphenidate. One patient was switched because of a neuroleptic-induced movement disorder, and one had no history of antipsychotic medication. Patients were followed up only for periods ranging from 2 weeks to 4 months, because AIDS dementia is a terminal-stage condition for AIDS patients. RESULTS: Patients varied in age from 28 to 57 years. Risperidone dosages ranged from 0.5 mg daily to 1 mg twice daily. Most patients received an adjunct benzodiazepine, antidepressant, or mood stabilizer. Within a week or so after starting risperidone, six of the nine patients exhibited brighter mood, were less agitated or aggressive and more cooperative, and participated more frequently in social activities. Two patients became increasingly agitated or psychotic, and came under control only after risperidone was stopped and replaced with haloperidol. One patient was transferred to a psychiatric unit, because of increased paranoid delusions and auditory hallucinations. CONCLUSIONS: Risperidone effectively controlled behavioral disturbances associated with AIDS dementia in 6 of 9 patients. Risperidone may be an alternative to conventional neuroleptics in patients susceptible to neuroleptic-induced movement disorders or unresponsive to neuroleptics and adjunct psychotropic agents.

AIDS Dementia Complex↗

Attitudinal, social, and practical correlates to fitness behavior: a test of the theory of planned behavior.

Professional management personnel (N = 73) who exercise were studied to assess the efficacy of the theory of planned behavior in predicting intention to exercise and amount of exercise. Four rating scales were used for the assessment of attitude toward fitness, subjective norm, perceived behavioral control, and intention to exercise. In addition, frequency of exercise was measured and recorded for five months. Hierarchical multiple regression analyses indicated that 26.6% of the variance of intention to exercise was contributed by both fitness attitude and subjective norm, with the unique contribution of attitude toward fitness (part r = .36) slightly greater than that of subjective norm (part r = .33). 8% of the unique variance of exercise was explained by intention to exercise. Hierarchical multiple regression analyses also indicated that perceived behavioral control did not account for a significant variance in intention to exercise but did account for a significant variance in amount of exercise (R2 change = .21). In the environment in which it was tested, results support the theory of planned behavior for understanding the exercise behavior of professional management personnel who exercise.

Adult↗

Predicting physical activity promotion in health care settings.

PURPOSE: To test the ability of the theory of planned behavior (TPB) in predicting the stage of change for physical activity promotion by mental health professionals. DESIGN: Six-month prospective questionnaire study. SETTING: One mental health trust in the East Midlands, United Kingdom. SUBJECTS: Three hundred ninety-four mental health professionals (men, n = 131; women, n = 263) of an initial sample of 477 participated in the study (83% response rate). MEASURES: Attitudes, subjective norms, intentions, perceived behavioral control, and stage of change were measured at the first wave of data collection. Stage of change was also assessed 6 months later. Data were analyzed using structural equation modeling. RESULTS: Intention and stage of change were successfully predicted from TPB variables. Overall, 27% of the variance in self-reported stage of promoting physical activity was explained by the model. Sixty-one percent of the variance in intention to promote physical activity was explained. When included, past behavior was the strongest predictor of both intention and stage of change and attenuated all other path coefficients. Past behavior improved the predicted variance in intention by 11% and stage by 6%. CONCLUSIONS: The TPB variables of attitude, subjective norms, perceived behavioral control, and intention predict stage of change of physical activity promotion in a health care setting. However, promoting physical activity in the past had a sizable effect on predicting subsequent promotion. Due to unequal distribution across stages, the stage model's application to understanding the behavior of health professionals may be limited.

Adult↗

Adolescents' perceptions of family functioning in the United Arab Emirates.

A sample of 710 subjects between 14 and 19 years of age were examined to assess psychological health of United Arab Emirates (UAE) families with adolescent members. The Family Functioning Questionnaire (FFQ) based upon the adolescent's perception of his or her family life and climate contains seven dimensions that constitute the family functioning process: family structure, emotional fulfillment, internal relations, behavioral control, value transmission, basic requirements, and external relations. Results indicate that the adolescents perceived their families to be operating more toward the functional than dysfunctional end of the scale. Males scored their families more functional in family structure and in external relations more significantly than did females. Females perceived their families as more functioning in internal relations, behavioral control, and basic requirements. However, a trend was found in favor of males on emotional fulfillment. Family functioning scores were higher in upper social economic status (SES) families than in other SES levels.

Adolescent↗

Surface and bulk modifications to photocrosslinked polyanhydrides to control degradation behavior.

A unique class of surface-eroding polyanhydrides was developed and explored for use in medical applications requiring high-strength biomaterials (e.g., orthopedics). In particular, dimethacrylated anhydride monomers were synthesized that photopolymerize quickly to render densely crosslinked polymer networks that degrade from the surface only by hydrolysis of labile anhydride linkages. Previous research on these materials has shown that the rate of hydrolysis of the degradable linkages is dependent on the hydrophobicity of the network composition. This article demonstrates the versatility in controlling the degradation process and resulting cellular response in these materials through the incorporation of new chemistries and the formation of polymer-polymer composite structures. Specifically, the rate of mass loss was controlled by the addition of hydrophobic linear polymers [e.g., poly(methyl methacrylate)] or monovinyl monomers based on hydrophobic natural components (e.g., cholesterol, steric acid). In addition, a newly established photografting method was used to modify the network surface chemistry with cholesterol- and stearic acid-based polymer grafts to control the degradation front and cellular interactions at the polymer-tissue interface. Finally, a porogen leaching method was used to form porous polyanhydride constructs, which can be subsequently filled with osteoblasts photoencapsulated in a hydrogel, as potential synthetic allograft materials for tissue engineering bone.

Anhydrides↗

Ap-let neurons--a peptidergic circuit potentially controlling ecdysial behavior in Drosophila.

Here we describe a novel set of peptidergic neurons conserved throughout all developmental stages in the Drosophila central nervous system (CNS). We show that a small complement of 28 apterous-expressing cells (Ap-let neurons) in the ventral nerve cord (VNC) of Drosophila larvae co-express numerous gene products. The products include the neuroendocrine-specific bHLH regulator called Dimmed (Dimm), four neuropeptide biosynthetic enzymes (PC2, Fur1, PAL2, and PHM), and a specific dopamine receptor subtype (dDA1). For the PC2, Fur1, and PAL2 enzymes, and for the dDA1 receptor, this neuronal pattern represents the vast majority of their total expression in the VNC. In addition, while Dimm and PHM are present in the peritracheal Inka cells in larvae, pupae, and adults, Ap, PC2, Fur1, PAL2, and dDA1 are not. PC2, PAL2, and DA1 receptor expression were all controlled by both dimm and ap. Previous genetic analysis of animals deficient in PC2 revealed an abnormal larval ecdysis phenotype. Together, these data support the hypothesis that the small cohort of Ap-let interneurons regulates larval ecdysis behavior by secretion of an unidentified amidated peptide(s). This hypothesis further predicts that the production of the Ap-let neuropeptide(s) is dependent on each of four specific enzymes, and that a certain aspect(s) of its production and/or release is regulated by dopamine input.

Animals↗

Overview: Ethical issues in contemporary psychiatry.

The authors survey the ethical problems confronting psychiatry today. They state that with rare exceptions psychiatric intervention can be morally justified only with the potential patient's informed consent. Within this framework, they discuss the fact that today nonpsychiatrists, particularly ethicists, lawyers, legislators, and social scientists, as well as psychiatrists are concerned about medical ethics, specifically regarding the right to be treated, the right not to be treated, the civil rights of psychiatric patients, the ethics of behavior control, the problem of conflicts of interest in therapeutic goals, privacy and confidentiality, the ethics of human experimentation, policy decisions, and psychiatry's relationship to the changing moral value structure of U.S. society.

Attitude to Health↗

Decrease in functional residual capacity during inspiratory loading and the sensation of dyspnea.

The purposes of the present study were to determine the changes in functional residual capacity (FRC) during inspiratory loading and to examine their mechanisms. We studied seven normal subjects seated in a body plethysmograph. In both graded inspiratory elastic (35, 48, and 68 cmH2O/l) and resistive (21, 86, and 192 cmH2O.l-1.s) loading, FRC invariably decreased from control FRC and phasic expiratory activity increased. The reduction in FRC was greater with greater loads. A single inspiratory effort against an inspiratory occlusion at three different target mouth pressures (-25, -50, and -75 cmH2O) and durations (1, 2, and 5 s) also resulted in a decrease in FRC with an increase in expiratory electromyogram activity in the following expiration. The decrease in FRC was greater with greater target pressure and duration. This decrease in FRC is qualitatively similar to that during inspiratory loaded breathing, and we suspect that the same mechanisms are at work. Because neither vagal nor chemoreceptor reflex can account for these responses, we suspect conscious awareness of breathing or behavioral control to be responsible. In an additional study, the sensation of discomfort of breathing during elastic loading decreased with a decrease in FRC. These results suggest that the reduced FRC may be due to behavioral control of breathing to reduce the sensation of dyspnea during inspiratory loading.

Adult↗

Changing through doing: behavioral influences on the brain.

It seems self-evident that the brain controls behavior but does behavior also "control" the brain? This chapter examines evidence that behavior can and does influence specific aspects of brain structure and function. Evidence for such influence is easily obtained on an evolutionary time scale, since the selective forces found in the ecological niche of the animal are typically reflected in its sensory and motor activities as well as its body shape and behavioral habits. Similarly, during development, there is ample evidence that the behavior acts in concert with the environment to establish structural changes in the brain that last a lifetime. Perhaps most surprisingly there is now evidence that social behavior can cause changes in the brain in adult animals and that these changes are reversible. The changes caused by behavioral interactions can be dramatic and typically are related to reproductive behavior. Understanding the mechanisms responsible for dynamic changes in the nervous systems of adult animals is a major challenge and the discovery that it can occur may lead to insights about other systems where behavior sculpts the brain.

Animals↗

Effects of drugs on behavior in rats maintained on morphine, methadone or pentobarbital.

Dose-effect curves were determined for the effects of drugs on responding under a multiple fixed-ratio 10-response fixed-interval 90-sec schedule of food presentation before and during chronic exposure to drugs in the drinking water. In rats consuming 70 to 90 mg/kg of morphine per day, the dose-effect curves for the rate-decreasing effects of morphine on responding under both schedule components shifted 1/2 log unit to the right, but the dose-effect curves for methadone, pentobarbital and d-amphetamine showed little change. In rats consuming 30 to 55 mg/kg of methadone per day there was little change in the dose-effect curves for the rate-decreasing effects of methadone and d-amphetamine on responding, but the dose-effect curve for morphine shifted 1/2 log unit to the right and the dose-effect curve for pentobarbital shifted upward and to the right. In rats consuming 40 to 50 mg/kg of pentobarbital per day, the dose-effect curve for the rate-decreasing effects of pentobarbital shifted to the right by about 1/4 log unit, and there was a similar but less marked shift to the methadone dose-effect curve to the right. In rats consuming pentobarbital, the morphine dose-effect curve was little changed. These experiments suggest that chronic methadone consumption confers greater tolerance to the effects of morphine on schedule-controlled behavior than it confers upon itself, while chronic morphine consumption confers greater tolerance to its own behavioral effects than it does to those of methadone. There appears to be some reciprocal cross-tolerance between methadone and pentobarbital for schedule-controlled behavior, but not between morphine and pentobarbital.

Animals↗

Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in rats.

To investigate the contribution of the anterior cingulate cortex (ACC) to stimulus-reward learning, rats with lesions of peri- and postgenual ACC were tested on a variety of Pavlovian conditioning tasks. Lesioned rats learned to approach a food alcove during a stimulus predicting food, and responded normally for conditioned reinforcement. They also exhibited normal conditioned freezing and Pavlovian-instrumental transfer, yet were impaired at autoshaping. To resolve this apparent discrepancy, a further task was developed in which approach to the food alcove was under the control of 2 stimuli, only 1 of which was followed by reward. Lesioned rats were impaired, approaching during both stimuli. It is suggested that the ACC is not critical for stimulus-reward learning per se, but is required to discriminate multiple stimuli on the basis of their association with reward.

Amphetamine↗

Identification of amino acid residues that control functional behavior in GluR5 and GluR6 kainate receptors.

GluR5 and GluR6 kainate receptors differ in their responses to a variety of agonists, despite their relatively high primary sequence homology. We carried out a structure-function study to identify amino acids underlying these divergent responses. Patch clamp analysis of chimeric GluR5-GluR6 receptors indicated that several functionally dominant sites were localized to the C-terminal side of M1. All nonconserved amino acids in the region between M3 and M4 of GluR6 were then individually mutated to their GluR5 counterparts. We found that a single amino acid (N721 in GluR6) controls both AMPA sensitivity and domoate deactivation rates. Additionally, mutation of A689 in GluR6 slowed kainate desensitization. These functional effects were accompanied by alterations in binding affinities. These results support a critical role for these residues in receptor binding and gating activity.

Amino Acid Sequence↗