[The outlook of research on common cross-reacting and species-specific antigens in bacterial species of the genus Pseudomonas].
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Immunological relationships have been investigated with acid and alkaline phosphatases, cystine aminopeptidase, beta-acetylglucosaminidase, beta-glucuronidase, catalase and L-glutamate dehydrogenase of human, monkey, mouse, rat, rabbit, dog, cattle, sheep, cat, pig, guinea-pig and chicken organ extracts by means of immunodiffusion and immunoelectrophoresis. Extensive cross-reactions among the antigens of most of the enzymes were observed. However, enzymic proteins of acid and alkaline phosphatases, cystine aminopeptidase, beta-acetylglucosaminidase and beta-glucuronidase were found to possess primate and/or human-specific antigenic determinants.
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Extracts were prepared by the 3M KCl method from fetal tissues of human, mouse, cattle, pig, sheep, cat, guinea pig, and chicken origin. Lymphocytes of tumor bearing mice and tumor patients reacted specifically in the MEM-test with antigenic components of the extracts. The cellular sensitization of the tumor-bearer was not correlated with the localization and the histologic type of the tumor. The cross-reacting oncofetal antigens obviously represent phylogenetically conserved structures.
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Several studies conducted in diverse fields indicate the presence of a genetic discontinuity within the taxon Galago crassicaudatus E. Geoffroy--the thick-tailed bushbaby. One of these areas is morphology. This contribution details a statistical analysis of skull material classified under this taxon in order 1) to confirm the objective existence of two morphotypes, and 2) to investigate the characters that allow the skull types to be distinguished. Emphasis is placed on multivariate techniques, although univariate and bivariate techniques are included where they are felt to be appropriate. All statistical analyses point to the reality of the morphological discontinuity between the groups. This is true even when size considerations have been reduced by rescaling the data. The results support separation of the populations at a specific level: G. crassicaudatus and G. garnettii. In addition, the structural changes observed in the two taxa--including an increase in overall size in G. crassicaudatus--are indicative of a divergence in preferred habitats: G. garnettii is adapted to more mesic environmental conditions, and to a softer, less fibrous diet than is its more robust sibling.
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