Epidemiology of scabies: the new epidemic.
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Psoroptes ovis [Hering] mites and sucking lice (Linognathus vituli Linnaeus) were eliminated from light to heavily infested calves with a single subcutaneous injection of nifluridide in five separate experiments. The compound was incorporated in a copolymer vehicle in a sesame oil suspension. In the first two experiments, mites were eliminated within 10 days following a 20 mg kg-1 injection. Eight out of 9 calves were cleared of mites within 7 days post injection of nifluridide at 4, 6 and 9 mg kg-1 in the third experiment. At the end of the 65 day trial, no live mites were isolated from any of the treated animals. In the last two experiments nifluridide eliminated sucking lice populations at all dosage levels. Complete control of the biting lice (Bovicola bovis) was not obtained. No toxic signs were observed in treated calves.
Fenvalerate [Cyano(3-phenoxyphenyl)methyl-4-chloro-alpha-(1-methylethyl) benzene acetate] was evaluated as a one- or two-dip treatment at two different concentrations against cattle infested with Psoroptes ovis (Hering). One or two dips at 0.025% or one dip at 0.05% failed to eliminate P. ovis; two dips in fenvalerate at 0.05% provided complete elimination of all mites. Fenvalerate was equally effective against male, female, and immature mites, but did not exhibit ovicidal properties.
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