[High-frequency jet ventilation. A new technic for artificial respiration].
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Acute lung disease is commonly associated with interstitial pulmonary edema and a tendency towards partial or total alveolar collapse. To counteract this tendency mechanical ventilation is successfully used in most cases. Mechanical ventilation, however, leads to a harmful retention of water and salt, which may worsen interstitial pulmonary edema and further impair gas exchange. This problem seems to be less known. A survey of the effects of currently used modes of mechanical ventilation on excretory function and hemodynamics of the kidneys is given together with a short review of the possible afferent and efferent mechanisms which mediate the renal response to mechanical ventilation. Some clinical suggestions are made to break through the vicious cycle between mechanical ventilation and kidney function.
A new respiration system is described. The system has been developed for the therapy of very ill newborn and premature infants (RDS stage IV, gestation age less than 28 weeks, severe pneumonia etc.). The special feature of the new respiratory device is an alternating between cycles with low frequencies and relatively high amplitudes, and breathes with low amplitudes and relatively high frequencies.
Significant changes in oxygen uptake (VO2) and carbon dioxide output (VCO2) as well as resting energy expenditure (RMR) can be observed in critically ill patients. Reliable data, although needed by the clinician especially in long term ventilated patients, have not been obtainable so far. We developed a modular system which provides by means of mass-spectrometry, accurate reproducible results. Furthermore, the design of the gas sampling module minimalizes systemical failures in the expiratory branch. Two groups of polytraumatized patients (n = 10, n = 7 respectively) with different amounts of intravenous amino-acid support and identical energy supply were included in the study. During the first week all patients showed significantly elevated values for VO2 and VCO2 with a tendancy to increase. High amino-acid supply resulted in higher rate of gas exchange and disproportional increase in energy expenditure. Subsequently reduced carbohydrate intake was found to be effective in reduction of gas exchange earliest after 24 h. Oxidation rates for glucose and fat did not correspond to energy supply ratio of substrates. It can be stated that in polytraumatized patients amino-acid supply more than 75 g/24 h/m2 is not economical in terms of energy gains and is therefore not generally recommended. Reduction of carbohydrates in the weaning period of respirator in these patients is likely to be effective only in borderline cases and started early before weaning (greater than 24 h). Energy supply by means of carbohydrates should exceed the energy derived from fat supply in the nutritional regime according to oxidation rates in polytraumatized patients.
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A general interdisciplinary survey of trends within intensive care units is necessary in order to further reduce the risk of laryngo-tracheal injury requiring treatment after prolonged intubation. Endoscopic controls of the larynx and cervical trachea should be recommended as urgent during long intubations, to ensure that a secondary tracheotomy does not ultimately occur too late. Only a perfectly performed tracheotomy minimises complications (stenoses). Repeated laryngoscopy and endoscopy of the trachea with a fibreoptic system (a few days after extubation) is recommended after every prolonged intubation.
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