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[Cystic pyeloureteritis. A diagnosis to keep in mind].

OBJECTIVES: Cystic pyeloureteritis is a disease entity of unknown etiology and unspecific symptoms. It is incidentally detected and is difficult to distinguish from other disorders showing filling defects on urographic evaluation. All the foregoing prompted us to report the present case. METHODS/RESULTS: We report a case of cystic pyeloureteritis that had been diagnosed during ureterorenoscopy in a patient with lithiasis and recurrent urinary tract infection. The etiopathogenesis, diagnostic and therapeutic aspects described in the literature are briefly reviewed. CONCLUSIONS: We underscore the importance of confirming the diagnosis by endoscopic and cytological studies. Conservative management is advocated. Patient follow up should include urinalysis, urine culture and cytology twice yearly and intravenous urography once a year.

Aged↗

[Studies of the etiology of cystopyelitis in hybrid swine].

Studies were carried out on the etiology, clinical picture, morphologic changes, and methods of prophylaxis of the cystopyelitis in hybrid pigs. It was established that in the cases studied the etiologic part is most probably played by Escherichia coli having pronounced virulence for albino mice. Clinically the disease was manifested with hematuria--the cardinal diagnostic symptom; histologically there were nephritis, pyelonephritis, and strong edemas on the wall of the bladder. When hematuria appeared the affected pigs died (at the rate of 100 per cent) as a result of acute anemia. Prophylactic measures have been especially successful with the use of streptomycin to which the isolated coli strains proved sensitive.

Animals↗

[Cystic pyeloureteritis. A review of the literature in the period of 1946-1994 and a report of a new case].

Presentation of a new case of unilateral cystic pyeloureteritis in a 46-year old female patient. The condition presented as a right renoureteral colic. A revision is made of the 69 national cases published on such an uncommon condition, of obscure etiologic, pathogenic and therapeutical features. The accent is placed on its most significant aspects, such as: difficulties of differential diagnosis with other repletion defect imagen in the excretory tract and their frequent association to other diseases.

Cysts↗

[Localizationstudies in female patients with recurrent urinary tract infection. III. Patients after successfull antireflux-operation (author's transl)].

In 14 girls and 5 women with recurrent urinary tract infections after successfull antireflux-operation we performed 72 bladder-wash-out-tests. Whereas preoperatively 50% of the patients had a supravesical bacteriuria, only 25% had it postoperatively. Most of the postoperativ vesical and supravesical bacteriurias were interpreted as reinfections. The demonstrated postoperativ ascension of bacteria in the upper urinary tract in spite of successfull surgical treatment cannot be taken as an argument against operation. The postoperative supravesical bacteriurias are less frequent and have less morbidity than the prepoerative supravesical infections.

Adult↗

The influence of the SOS response on the activity of 4-quinolones and zidovudine against some strains of Enterobacteria.

The 4-Quinolones are known to induce the SOS response. This should also be the case with AZT (Zidovudine) which has the same bactericidal mechanism. SOS response might make the bacteria more sensitive or more resistant to subsequent doses of quinolones and AZT. NA (Nalidixic acid), the first quinolone of the early 1960s, sensitises a strain of E. coli isolated from the urine of patients with cystopyelitis and the E. coli AB1157 wild type strain which is a well-known SOS inducer. In this case, the SOS system is not involved but only the recombination repair mechanisms which make the bacteria more susceptible to further damage by NA. On the contrary, CPX (Ciprofloxacin) protects E. coli from further exposure to antibiotics. Therefore the SOS response induction assists the bacteria in recovering from the DNA damage caused by CPX. The SOS response induced by AZT in the tested E. coli strains does not seem to either contribute to the lethality of the drug or to be involved in protecting bacteria from the damage caused by AZT. In fact, the percentage of killing was the same for both pre-treated and non pre-treated bacteria (p = 0.5). On the contrary, it was found that in Salmonella typhimurium belonging to blood of a patient with recurrent bacteriaemia, the CPX added to pre-treated bacteria with AZT was less lethal than when it was added to non pre-treated bacteria. The SOS response, in this case, protects bacteria from the damage caused by AZT.

AIDS-Related Opportunistic Infections↗

[Carcinoma of the bladder in childhood (author's transl)].

The authors describe the extremely rare finding of a keratinized squamous cell carcinoma of the bladder in a 13 year old girl without however a history of the typical symptoms of the illness such as hematuria. The findings are reviewed in the light of the current literature. Enuresis leading to a chronic infection of the urinary tract is discussed as the possible etiologic factor.

Adolescent↗