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Results for “Pupil Disorders”

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At least 631 records · Page 35Linked to original sources
PubMed1997

[Pupillary diameter and pupillary reactions in heroin dependent patients and in patients participating in a methadone and morphine replacement program].

The computer-assisted static and dynamic light evoked pupillometry (TV-pupillometer 1050, Whittaker Corp.) had been proved to be a sensitive procedure for assessment of the effect of psychoactive drugs. Therefore, this method was used in 26 heroin dependent patients (mean age 24.42 years), 20 methadone substituted patients (mean age 29.75), and 20 morphine-substituted patients (mean age 30.65 years) to answer the question whether there were no differences within the patient groups but significant differences between the patients and healthy normals. Indeed, pupillary diameter (vegetative activation) as well as relative change (pupillary reagibility) showed no significant differences between the heroin dependents, the methadone substitution group and the morphine substitution group. However concerning pupillary diameter and relative change the patient groups differed significantly from the healthy controls. Onset latency revealed no differences within the patient groups and between patient groups and healthy controls respectively. Thus the variable pupillary diameter and relative change could be used to assess the additional application of opiates in patients participating in a substitution program.

Adult↗
PubMed1977

Glaucoma in oculodermal melanocytosis.

Case reports of oculodermal melanocytosis (nevus of Ota) and ipsilateral glaucoma often have other ocular disorders which could account for the glaucoma. It has not been clearly shown that the oculodermal melanocytosis alone can cause secondary glaucoma. In the present case report, optic nerve head and visual field changes, suggestive of a long-standing unilateral elevation of intraocular pressure, occurred in an eye with oculodermal melanocytosis and no other apparent ocular disorder to account for the chronic glaucoma.

Adult↗
PubMed1997

Ocular and orbital complications of intraarterial cisplatin. A case report.

Despite advances in neurosurgery, radiation oncology, and chemotherapy, the prognosis for glioblastoma multiforme remains poor, with a median survival time of 11-12 months. Cisplatin (cis-diamminedichlorideplatinum II) is one treatment for glioblastoma multiforme. Higher response rates have been achieved by intraarterial (i.a.) infusion than by systemic infusion of this agent. Cisplatin therapy may cause neurologic complications, and i.a. delivery has been reported to cause ocular toxicity. We report a patient who experienced intraorbital and intraocular toxicity following supraophthalmic i.a. injection of cisplatin.

Adult↗
PubMed1998

Methanol-induced vision loss.

BACKGROUND: Accidental or purposeful consumption of small amounts of methanol can lead to severe vision loss or death. Vision loss is rapid--usually symmetric--and most often affects the central (or centrocecal) visual field, although peripheral visual loss may occur as well. Fixed, dilated pupils and optic atrophy, with or without excavation, are the most common findings in persons with methanol-induced vision loss. CASE REPORT: A 35-year-old man was examined after consuming methanol in the form of windshield wiper fluid. Despite relatively rapid treatment for the patient's methanol poisoning and associated metabolic acidosis, permanent, severe vision loss with associated optic neuropathy developed. Because of the finding of fixed, dilated pupils on the patient's initial presentation, severe vision loss was an expected result for this patient. CONCLUSIONS: Prompt recognition and proper medical treatment are the main factors in successful management of methanol poisoning. Even if proper and timely medical response is achieved, however, the patient may still experience permanent neurologic sequelae or death. Notably, pupillary status may provide the best prognostic information for both morbidity and mortality.

Acidosis↗
PubMed1997

[Late effects after anterior intraocular lens implantation].

MATERIAL AND METHODS: During ten years, 890 operations of cataract with anterior chamber intraocular lens implantation were performed. TWO GROUPS OF EYES WERE OBSERVED: Eyes after planned intracapsular cataract surgery and eyes in which intraoperative complications occurred making impossible to apply posterior IOL. PURPOSE: To evaluate late complications and functional status of the eye. RESULTS: Our results indicate that anterior chamber intraocular lens implantation yields in many cases good visual acuity and, although not free of complications, is a safe procedure.

Aged↗
PubMed2002

Psychiatric disorders of children and adolescents--a growing problem at school.

The purpose is to present the views of comprehensive school and senior secondary school teachers working in the Oulu province in Northern Finland concerning the behavioural and emotional disorders of their pupils, the actions taken by teachers to refer pupils for consultation, and the functionality of mental health services. The data were collected by questionnaires in 1998 and 2000. According to the teachers' estimates, the behavioural and emotional disorders of pupils have both increased in number and become more severe at all levels of primary and secondary education. The teachers of comprehensive schools and special schools mostly contacted the parents when a pupil was found to have psychiatric symptoms. At the early stages of referral the teachers often also consulted with the pupil welfare team for support. The teachers of senior secondary schools contacted primarily the school nurse and secondarily the parents. Teachers were content with the psychiatric health care services if their pupils benefited from them, but the availability of services and the flow of information were problems. It was also difficult to decide when to refer a pupil for consultation and treatment. The responsibilities and obligations for the availability and functionality of mental health services for children and adolescents were re-defined and specified in a statute enforced as of January 2001. The question is how can we convert responsibilities and obligations into practical action?

Adolescent↗
PubMed1976

Hereditary sensory neuropathy and tonic pupils.

The clinical features of two siblings with both hereditary sensory neuropathy and bilateral tonic pupils are described. Other neurologic disorders associated with tonic pupils are reviewed. Our patients appear to represent a unique instance of the association of disorders that primarily affect the ciliary and dorsal root ganglia.

Adult↗
PubMed2005

Mydriasis due to Datura inoxia.

Unilateral, dilated unresponsive pupil may be secondary to a wide range of ocular and neurological disorders. "Gardener's pupil" is a pharmacological mydriasis caused by exposure to plants containing alkaloids. We report a case of mydriasis related to Datura inoxia, and detail a number of plants that have toxic effects. This report emphasises the importance of accurate history taking when evaluating fixed dilated pupil. We recommend that labelling of such poisonous plants should detail the local and systemic effects of accidental exposure, rather than merely the fact that they are poisonous.

Aged↗
PubMed2006

[Three cases of corneal disorders associated with an oral anticancer drug S-1].

PURPOSE: S-1 is a new oral anticancer drug containing tegafur, which is a prodrug of 5-fluorouracil. In this report, we describe the clinical features of three patients who suffered corneal disorders that seemed to be caused by S-1 administration. CASES: One female and two male patients, whose ages ranged from 57 to 69 years, were entered in this study. Between 3 to 14 months after they started oral S-1 therapy, they experienced sudden visual reduction. They all had corneal disorders, which occurred in the inferior and the superior areas, and progressed toward the center. As the corneal disorders invaded the pupil area, the patients noticed visual disturbance. They recovered their vision and their corneal disorders diminished when the drug was discontinued. However, after the drug intake was resumed, the corneal disorders occurred again in some cases. All patients also had lacrimal obstructions. CONCLUSION: S-1 treated patients should be followed carefully for ophthalmic complications because corneal disorders are likely to appear.

Administration, Oral↗
PubMed2004

[Study of the prevalence of disturbance of activity and attention and co-morbid psychiatric disorders in the sample of Kaunas city primary school pupils].

Aim of the study was to evaluate the prevalence of disturbance of activity and attention and co-morbid psychiatric disorders among the primary school children in Kaunas city. Parents and teachers of all pupils of 12 randomly selected primary schools (N=2942) were asked to fill the scales on the presence of disturbance of activity and attention symptoms in their children. Disturbance of activity and attention was diagnosed if at least 6 symptoms of hyperactivity and/or 6 symptoms of inattention were present for at least 6 months according parents reports in DuPaul-IV scale and the result of teachers CAP scale exceeded the norms for age and gender. Both scales were obtained for 2298 pupils--1096 girls and 1202 boys 6-12 years of age. Disturbance of activity and attention was diagnosed for 5.2% of primary school pupils. It was 1.9 times more frequent among boys than among girls. Prevalence of co-morbid psychiatric disorders was estimated individually interviewing suspected children and their parents using M.I.N.I. Kid questionnaire. Out of all disturbance of activity and attention diagnosed children, 52.5% were also diagnosed co-morbid psychiatric disorders, most frequently oppositional defiant disorder (31.3%) and different types of anxiety disorders (18.0%). Prevalent type of disturbance of activity and attention and co-morbid disorders was related with the age of the pupils. Symptoms of hyperactivity and co-morbid psychiatric disorders had influenced motivation of parents to seek treatment for their children. Forty percent of the parents of children, who were diagnosed disturbance of activity and attention, have applied to the mental health care professionals; most of them evaluated the help they received as partly useful (57.9%) or not useful at all (26.3%).

Age Factors↗
PubMed1984

Decrease of visual acuity in patients with clear media and normal fundi. Objective screening methods for differentiation and documentation.

For differentiation of unilateral reduction of visual acuity in patients with clear media and normal fundi, the Swinging Flashlight Test was used. Optic neuropathies as a rule give pathological results. On the other hand refraction scotomas, functional amblyopias and malingering produce a normal outcome of this test in general. For documentation of afferent pupillary defects a photographic method is described. Electronystagmography is advocated as a method for detection of malingerers and neurotics among patients complaining of acute uni- or bilateral visual acuity reduction. Optokinetic nystagmus is recorded using Bangerter's filters in front of the patient's eye. This method allows a certain estimation of the visual acuity.

Electronystagmography↗
PubMed1995

Oval pupil in patients with diabetes mellitus: examination by measurement of the dark-adapted pupillary area and pupillary light reflex.

Determination of the dark-adapted pupillary area (DAPA) by infrared photography revealed that some diabetic patients show corectopia (oval pupil) in addition to the small DAPA as pupillary abnormalities. The prevalence and clinical details of oval pupil were compared between diabetic patients and healthy subjects. Pupillary light reflexes were also analyzed with an infrared videopupillography in some of the diabetic patients. The healthy subjects were examined for the influence of age on the ratio of the pupillary diameter of the major and minor axes. The ratio was 1.04 +/- 0.02 (mean +/- S.D.) in the healthy subjects, and cases in which the ratio was +2 S.D. or higher than the mean ratio were defined as oval pupil. Oval pupil was observed in 21 (24%) of 86 diabetic patients, and was correlated with heart rate variation (P < 0.05) and DAPA (P < 0.01), which represent an autonomic dysfunction. Quantitative analysis of pupillary light reflexes with an infrared videopupillography revealed that the dark-adapted pupillary area before photic stimulation (P < 0.01) and the maximum %-velocity of constriction (P < 0.05) were significantly less in the oval pupil group than in the round pupil group. Cranial magnetic resonance imaging revealed no abnormalities in the oval pupil group. From these results, a peripheral autonomic disorder was implicated in the etiology of oval pupils in diabetic patients.

Adult↗