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Results for “Postphlebitic Syndrome”

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At least 631 records · Page 35Linked to original sources
PubMed1990

[Social medicine importance and treatment strategy of chronic venous diseases].

In European states chronic diseases of the veins are a remarkable social medical problem. Representative random investigations of the population in the GDR resulted in a medically significant chronic venous insufficiency of the legs in 14% of the adult population. The annual fresh disease rate concerning the medically significant type varicosis is 1.5%. The highest incidence rates are between the 20th and 40th year of age. A therapeutic need of recovery is the result. Only the early active therapy in the sense of a sanation of the disease is able to prevent severe forms of the course. Effective primary preventive measures are not yet known. The treatment of patients suffering from venous diseases is part of the basic medical care in the territory. The basis therapy should remain in the hands of the general practitioners.

Adult↗
PubMed1990

[Phlebodynamometry studies in patients with chronic venous insufficiency and phlebography verified insufficiency of muscle veins].

23 patients with complaints in the sense of a chronic venous insufficiency were examined by means of phlebodynamometry, who phlebographically did not show any postthrombotic changes of the deep conducting veins, but had clear signs of an insufficiency of the muscle veins stage I-III. Cases with isolated insufficiency of the muscle veins (n = 5) and combination forms with additional insufficiency of the conducting veins and/or superficial varicosis (long and short saphenous veins) were found. Measured at the decrease of pressure (delta-p) after exercise in the combined forms the epifascial varicosis has the greatest haemodynamic effects. The isolated findings of an insufficiency of the muscle veins with or without additional insufficiency of the conducting veins has apparently only smaller haemodynamic effects. For the isolated insufficiency of the muscle veins normal limit values for delta-p could still be measured, which also could only insignificantly be bettered by application of a tourniquet. This knowledge is important for therapy planning.

Humans↗
PubMed1990

[Differential diagnosis of non-thrombotic insufficiency of the conductive veins].

The differential diagnosis of the non-thrombotic insufficiency of conducting veins is in general possible by anamnesis and clinical angiological examination, even if non-vascular diseases are taken into consideration. In other patients, particularly in isolated insufficiency of the conducting veins, in addition to this non-invasive and, if the occasion arises, invasive angiological methods must be used.

Diagnosis, Differential↗
PubMed1990

[Treatment of trophic ulcers of the lower extremities in elderly patients].

The article analyses the results of treatment of trophic ulcers of the lower extremities consequent upon chronic venous insufficiency in 199 elderly patients. Concomitant diseases were encountered in 82% of patients, which called for a differential approach to the choice of the method of treatment. Combined laser therapy in the system of complex treatment in 83 patients proved to be highly effective.

Age Factors↗
PubMedDate not supplied

[Lymphopathy in postphlebitic disease].

Embryology, anatomy and physiology clearly demonstrate the relationship and interactions between the venous and lymphatic systems. It was therefore logical to expect mutual repercussions of the two systems on the pathological process. In the course of the post-phlebitic disease, structural and functional anomalies of the superficial and deep lymphatic system are demonstrated y microfluoroscintigraphy and isotopic lymphoscintigraphy. The advantage of recognizing this associated lymphatic pathology lies in the resulting therapeutic strategy: combine the usual phlebological treatments with specific treatments of peripheral lymphatic stasis.

Dextrans↗
PubMed1989

[Local tissue changes in venous ulcers of the leg].

Authors investigated anaerobic metabolites (lactate, pyruvate), gas analyzes, pathohistological changes (light and electron microsc.) and regulatory agents in the local blood of venous ulcers. The cause of anaerobic disturbance is hypoxia and hypercapnia (hypostatic ulcers) and pathologic vasodilatation and arteriolo-venules shunts (postthrombotic ulcers). Pericapillary fibrin deposition aggravate tissue necrosis and destructions.

Humans↗
PubMedDate not supplied

[Varitest plethysmography].

Varitest plethysmography is a non-invasive diagnostic method of venous insufficiency based on the study of the emptying of leg veins by flexion movements and their subsequent filling. The Varitest records the curves and measurements of these two stages. The physiological bases of the test and its technique are presented. Our experience, following the first few cases, enabled us to identify three main groups of patients:--Patients presenting chronic symptoms, in whom the clinical examination was negative or not obvious;--Patients presenting a problem of differential diagnosis with a deep/superficial or mixed chronic venous insufficiency. It also enabled us to specify the results of the treatments. According to our results, Varitest is a simple, easy to reproduce method, presenting a sensitivity and specificity with regard to the clinical symptoms and the Doppler, of approximately 80%. Its negative aspects are the poor collaboration of the patients or their inability to be available in order to study acute venous thromboses.

Humans↗
PubMed1989

[Phlebologic indications for duplex sonography].

Duplex ultrasonography has all the features required considerably to enrich the angiological-phlebological diagnostic work-up in the doctor's office. It is a harmless, noninvasive, functional and morphological examination technique that is available at any time. Major application possibilities are to be seen in the diagnosis of deep vein thrombosis, in the differentiated evaluation of insufficiency of the major vein, in the direct representation of insufficient perforating veins, and, in particular, for providing highly informative monitoring of the success of therapeutic measures. At the present time, however, points that militate against its use in the doctor's office are the high price of the equipment, and the requirements for further training, which are difficult to meet in the case of practising physicians.

Blood Flow Velocity↗
PubMed1989

Skin flow and swelling in post-phlebitic limbs.

It has been demonstrated that skin blood flow of postphlebitic limbs is increased. Also the venoarteriolar response (VAR), i.e. precapillary vasoconstriction present in normal limbs on standing up, is reduced in limbs with venous insufficiency, resulting in capillary hypertension. The supine skin resting flow (SF) and the skin flow on standing (SF) have been measured with laser-Doppler in 30 normal lower limbs and 70 postphlebitic limbs with ambulatory venous pressure greater than 65 mmHg; also, the rate of ankle swelling (RAS) has been measured with strain-gauge plethysmography. The VAR was derived from VAR = 100* (RF-SF)/RF. The reduction of VAR and the increase in SF, which has been demonstrated in the postphlebitic limbs, correlated well with the rate of ankle swelling (RAS). The measurements of SF, VAR and RAS evaluate objectively the degree of impairment of the microcirculation because of severe venous disease. They offer the possibility to study the natural history and the effect of treatment of venous hypertensive microangiopathy.

Adult↗
PubMed1989

Evaluation of the microcirculatory effects of Venoruton in patients with chronic venous hypertension by laserdoppler flowmetry, transcutaneous PO2 and PCO2 measurements, leg volumetry and ambulatory venous pressure measurements.

The evaluation of the effects of venoactive drugs and particularly of Venoruton may be performed using microcirculatory parameters. Laserdoppler flowmetry may be used in association with PO2/PCO2 measurements. In this study we combined the microcirculatory evaluation with foot and leg volumetry to evaluate the effects of Venoruton in 15 patients with deep (popliteal vein) incompetence and venous hypertension, treated for 6 weeks. A control group of 20 patients was also evaluated. All these subjects were studied and selected according to ambulatory venous pressure measurements (AVP) and duplex scanning. Measurements were made at the internal perimalleolar region in constant temperature condition (23 degrees C). No variations of AVP or duplex scanning findings were observed after 6 weeks in both treated and untreated patients. Laserdoppler flowmetry showed a significant decrease of the resting flow (which was increased in all patients at the beginning of the study). An increased efficacy of the venoarteriolar response was also recorded together with an increased response of skin flow after increase of temperature in the perimalleolar region in patients treated with Venoruton. This was also associated with an increase of skin PO2 and with a decreased PCO2. In the control group no significant variations of these parameters were observed. Leg volume was also significantly decreased in the patients treated with Venoruton while no changes were observed in controls. In conclusion this study showed the efficacy of Venoruton in improving parameters altered in venous hypertension and the possibility of application of this microcirculatory model to study venoactive drugs used for treating venous hypertension.

Anticoagulants↗
PubMed1989

[Ultrasonic diagnosis of post-thrombotic disease of the lower extremities].

On the basis of a rich experience and developed techniques of examination the authors claim that ultrasonic scanning is a highly informative and safe method for the diagnosis of postthrombotic disease of the lower limbs which yields all the necessary data on the condition of the deep main veins. With the introduction of this method into wide clinical practice the disease will be diagnosed in time, its stage and form determined, and the performance of phlebography, which is still necessary, will be less frequent.

Adult↗
PubMed1989

[Duplex sonography diagnosis of deep leg- and pelvic vein thromboses].

The diagnosis of thrombosis of the deep leg veins or pelvic veins is usually established on the basis of technical procedures. Clinical signs such as swelling, erythema or warming are unreliable. Plethysmographic measures have a low specificity, nuclear medicine studies enable assessment, limited to the lower leg, only after 24 hours. Continuous-wave Doppler sonography, as is the case with plethysmography, does not allow differentiation between intra- or extravascular cause of the obstruction to flow; hemodynamically-unimportant, floating thrombi cannot be detected. Ascending phlebography is an invasive procedure exposing the patient to contrast medium with its possible allergic reactions, radiation and thrombosis or local inflammation. Duplex-sonography enables the combination of high-resolution ultrasonic B-imaging with a pulsed Doppler unit which provides a noninvasive means for direct visualization of the involved vessel. For the examination, preferably, linear scanners are employed with a frequency of at least 5 megahertz. With the patient in the supine position, first, the iliac vein, medial to the artery, is imaged, then the common femoral vein and the great saphenous vein (Figure 1). Then the patient is turned and the popliteal vein and, as far as possible, the veins of the lower leg are examined from the back. Direct proof of thrombosis is considered the documentation of intraluminal echo-intense structures (Figure 2) associated with absence of complete compressibility of the vascular lumen in cross-section with slight pressure of the transducer (Figures 3a and 3b).(ABSTRACT TRUNCATED AT 250 WORDS)

Blood Flow Velocity↗
PubMed1989

[Transpopliteal phlebography in the diagnosis of chronic diseases of the veins of the lower extremities].

From experience in 98 studies the authors claim that transpopliteal phlebography yields information on the condition of the popliteal and the tibial veins and the ostial valve of the small saphenous vein in retrograde, and on the condition of the femoral vein in antegrade administration of the radiocontrast medium. It is indicated for patients suffering from varicosity in ectasia of the popliteal and tibial veins, as well as when the results of clinical tests for competence of the valves of the small saphenous vein are doubtful. The absence of visualization of the femoral vein in ascending distal or retrograde femoral phlebography in patients with congenital venous dysplasia or with phlebothrombosis sequelae is an indication for antegrade transpopliteal phlebography.

Chronic Disease↗
PubMed1989

[The role of changes in venous capacity in the lower extremities in the pathogenesis of post-thrombotic disease].

From the results of examination of 91 patients with postthrombotic disease by radioindication methods the authors established that blood filling of the lower limbs increases in a horizontal position. Varicosity leads to further growth of regional blood volumes (RBV). No essential difference was revealed in blood filling in the recanalized and mixed forms of the postthrombotic disease. The increase of blood volume as compared to the initial value in these patients in an orthostatic position is below normal. Storage of blood in the lower limbs causes increase of the circulating volume (CV) at first, but after 5 years of the disease it leads to gradual reduction of the CV and increase of RBV. Excessive blood filling in the postthrombotic disease causes diminution of the resilient-elastic properties of the vein, makes the work of the muscular-venous pump of the leg difficult, and leads to microcirculatory disorders. Combined treatment for the purpose of removing the principal links of the pathogenesis is suggested.

Blood Volume↗