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At least 631 records · Page 35Linked to original sources
PubMed1988

[Clinico-pathochemical substantiation of the exacerbation phenomenon in patients with ischemic heart disease during treatment with the helium-neon laser].

Some pathochemical mechanisms of coronary disease aggravation in the course of laser therapy were assessed by means of the measurement of erythrocyte membrane lipids and phospholipids as well as plasma alpha-tocopherol and diene conjugate levels. The aggravation was associated with an activation of metabolic processes aiming to produce regeneration of membrane structures. The regeneration takes place in the presence of chronic deficiency of total phospholipids and inadequate antioxidant protection of biomembranes, therefore complete stabilization and normalization of their composition and activity is impossible.

Adult↗
PubMed1987

Low-energy helium neon laser treatment of thumb osteoarthritis.

Eighty-one patients with symptomatic osteoarthritis of the thumb took part in a blinded, controlled study to assess the effectiveness of 0.9 mw continuous wave HeNe laser treatment. The subjects were randomly placed in either a control group or a treatment group. In each group the carpometacarpal (CMC), metacarpophalangeal (MCP), and interphalangeal (IP) joints of the most symptomatic thumb were "treated" with 15 sec irradiations at four equally spaced intervals around each joint three times a week for three weeks. The same protocol was used for both groups except that a hidden switch on the laser was placed in the "on" position for the treated group and in the "off" position for the control group. Although the laser-treated group noted slightly lessened tenderness of the treated MCP and IP joints (p less than 0.01 and 0.05, respectively, Wilcoxon signed-rank test), and a small increase in three-finger chuck pinch strength (p less than 0.04, paired t-test), changes in ROM, pain, joint tenderness, grip and pinch strength, activity level, and medication use, did not significantly differ between the groups. Adverse effects were rare (one in each group), minimal, and subjective. We conclude that HeNe laser irradiation at 0.9 mw is safe, but that it is not an effective treatment of osteoarthritis of the thumb.

Clinical Trials as Topic↗
PubMed1988

[Effects of gastric mucosa irradiation with helium-neon laser on epithelial cells].

Effect of various doses of low-tense laser irradiation on proliferative and functional morphology of fundal gastric epitheliocytes in rats was studied by endogastric irradiation with the methods of histochemistry, autoradiography, transmission and scanning electron microscopy. It was shown that laser irradiation effect varied with its dose and was spread on gastric mucosa lying at the site of direct influence. The doses of irradiation that had no alternative effect induced reconstruction of epitheliocytes especially mucocytes indicating intensification of specific function in them, as well as an increase of proliferative activity.

Animals↗