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Bilateral radical neck dissection with unilateral internal jugular vein reconstruction.

OBJECTIVE: To describe and evaluate the functional and oncologic results of one internal jugular vein replacement after bilateral radical neck dissection (RND). STUDY DESIGN: A retrospective historical cohort study. METHODS: Since 1972 all patients (n = 9) undergoing bilateral RND with resection of both internal jugular veins had a reconstruction of one internal jugular vein. In six cases the RNDs were staged, and in three cases the RNDs were performed simultaneously. In every case a vascular reconstruction was performed with an autologous vein graft. All patients received radiation therapy, in five patients before and in four patients after the vein grafting. Functional results were evaluated in terms of postoperative head and neck and neurologic complications. In some patients a Doppler scan was performed to assess vein patency. Oncologic results are reported as relapse-free survival and mortality intervals. RESULTS: In all patients the postoperative course was uneventful, without neurologic complications. Facial edema was noted in four patients, mild in three and moderate in one. Two patients are alive, with follow-ups of 8 and 18 years. Seven patients are dead, two without evidence of recurrence, four with cervical recurrence after a mean survival of 10 months, and one after distant metastasis after a survival of 7 years. In patients with long-term survival a Doppler scan confirmed the patency of the vein graft. CONCLUSION: The lack of operative complications and the absence of postoperative neurologic complications make a unilateral internal jugular vein replacement after bilateral RND attractive, although the oncologic results remain poor.

Adult↗

[Radical neck dissection and the possibility of complications: surgical technique].

Based on 15 pictures the technique of radical neck dissection is presented with particular attention to the topography of the neck. Steps by steps the possibility of complications is considered. During the operation the mandible branches of the facial nerve, vagus nerve, hypoglossal nerve, phrenic nerve, accessory nerve, shoulder plexus, cervical plexus, sympathetic trunk can be injured as well as the jugular vein, carotid artery, occipital artery, thoracic duct. The critical moments for generation of these complications are indicated.

Cranial Nerves↗

Superior sagittal sinus thrombosis after radical neck dissection.

Dural sinus thrombosis is a rare, potentially fatal complication of a radical neck dissection. The prognosis can vary from complete recovery to rapid death. Magnetic resonance venography provides an effective, noninvasive diagnosis. The goals of therapy are to decrease intracranial pressure and to lyse the thrombus. Systemic anticoagulation and systemic thrombolytics are controversial therapies. The direct intrasinus infusion of thrombolytic agents is under investigation.

Journal Article↗

[Calcium metabolism after thyroidectomy with modified radical neck dissection and parathyroid gland autotransplantation].

The issue of parathyroid autotransplantation in oncologic thyroid surgery is discussed controversially. In a series of 15 patients who underwent bilateral modified radical neck dissection for thyroid malignancy, parathyroid autotransplantation was carried out. Six months after surgery only one patient was hypoparathyroid, requiring permanent medication, thus autotransplantation is a safe procedure for the prevention of accidental hypoparathyroidism.

Adult↗

[Four cases of hypopharyngeal cancer treated with docetaxel, cisplatin, and 5-FU followed by radiotherapy and/or neck dissection].

We treated 4 patients with hypopharyngeal cancer, each of whom had a complete response after 2 cycles of chemotherapy with docetaxel, cisplatin, and 5-FU followed by radiation and/or neck dissection. Twenty-one months to 2 years after this therapy, 3 patients had no recurrence and no metastasis with their laryngeal framework and function preserved. Chemotherapy including docetaxel, cisplatin, and 5-FU is a useful treatment for early head and neck cancer.

Aged↗

[Experimental study on effect of intracranial pressure after different jugular vein ligation in neck dissection].

OBJECTIVE: To investigate the changes of ICP after different jugular vein ligation (JVL), search for a better fashion of JVI, and provide a scientific proof for neck dissection clinically. METHOD: Forty-eight rabbits were divided into 6 groups randomly that were taken for BC, BEJVL, BIJVL, RJVL, SBJVL and SJVL. Skull puncture technique was employed to get the values of ICP in 0 h, 0.5 h, 1.0 h, 2.0 h, 3.0 h, 4.0 h postoperatively. Necephalic tissue was removed from these rabbits after a week. We observed the quantity and area of glial cell by hematoxylin-eosin stain (HE). RESULT: ICP didn't increase in 4.0 h in control groups; After BEJVL, ICP increased slightly and fell to 0 h status within 4.0 h; After BIJVL and RJVL, ICP increased in some degree and decreased apparently in 4.0 h; After SBJVL and SJVL, ICP increased immediately and was lasting hightly after 4.0 h. The quantity and area of glial cell didn't modify apparently in BEJVL, BIJVL and RJVL, but proliferation and hypertrophy of those were observed significantly in SBJVL and SJVL. CONCLUSION: The patients suffered from BEJVL may require no prevent intracranical hypertension. The ones suffered from BIJVL and RJVL should be closely watched for degree of illness. The ones suffered from SBJVL and SJVL must be treated to prevent postoperative complications, such as intracranial hypertasion.

Animals↗

Short-term and long-term quality of life after neck dissection.

INTRODUCTION: Quality of life (QOL) is an important outcome measure in cancer therapy. Neck dissection (ND) morbidity has been well studied, but no study has focused on the quality of life after ND specifically. METHODS: Fifty-one patients who have undergone ND completed a 6-item quality-of-life survey with a 7-point frequency and interference response scale. General QOL and comorbidity biases were evaluated with the SF-12 questionnaire and the Charlson comorbidity index. RESULTS: The following symptoms were the most commonly experienced after surgery: neck tightness (71%), numbness or burning of the ear (57%), and shoulder discomfort (53%). However, interference with daily activities was reported by only 37%, 32%, and 33% of patients with these symptoms, respectively. Within 2 years of surgery, interference with daily activities decreased to 17%, 18%, and 12%, respectively. QOL after ND was negatively associated with previous radiation, previous chemotherapy, tumor stage, and more radical neck surgery but was positively associated with time after surgery. Shoulder discomfort and neck tightness had the greatest affect on QOL. CONCLUSIONS: Our results suggest that patients should receive preoperative counseling regarding the morbidities from ND and the possible short-term and long-term impact on QOL. Further studies evaluating the relationship between primary tumor characteristics and quality of life after ND need to be undertaken.

Adult↗

Good tumor control and survivals of squamous cell carcinoma of buccal mucosa treated with radical surgery with or without neck dissection in Taiwan.

The aim was to analyze the survival and prognostic factors in 232 patients with squamous cell carcinoma of the buccal mucosa (BSCC) treated with radical surgery with or without neck dissection (ND). The 5-year survivals for local, locoregional control, overall, disease-free, and disease-specific were demonstrated. Pathologic nodal status was the independent risk factor for local and locoregional control. Both pathologic nodal status and cell differentiation were the significant prognostic factors of disease-free survival. For cT1N0, 11.1% had neck metastases. All were tumor depth of > or =6 mm. Our result showed a relatively better tumor control and survivals in BSCC with radical surgery with or without ND. The possible reason may be due to the benefit from widely surgical resection with ND and post-operative radiotherapy or concurrent chemoradiotherapy in those with risk factors. In treating early cT1N0, we suggest that elective ND is indicated only when tumor depth > or =6 mm.

Adult↗

[Questionable indication for radical neck dissection in carcinomas of the tongue and floor of the mouth. Results after 4 years].

Based on a 4-year-study the use of ultrasound and preoperative treatment of the neck area is evaluated. The results suggest that there is no indication for radical neck dissection. The therapeutic approach described resulted in a considerable increase in the survival rate during the first 4 years as against the figures published by the DOSAK in 1988.

Austria↗

Interstitial brachytherapy and neck dissection for Stage III squamous cell carcinoma of the mobile tongue.

The purpose of this study is to describe the cause-specific survival rate, local control rate, salvage rate of neck metastasis, and post-treatment eating and speaking conditions for stage III mobile tongue squamous cell carcinomas and its subgroups. Between 1968 and 1999, 117 previously untreated patients with stage III mobile tongue carcinomas underwent mainly brachytherapy with external beam irradiation (EBRT) and neck dissection. A multivariate analysis was performed for the cause-specific survival rate on the various factors. The 1-, 3- and 5-year cause-specific survival rates for all patients were 76%, 54% and 54%, respectively. The 1-, 3- and 5-year primary control rates for all patients were 67.6%, 63.4% and 59.2%, respectively. There were statistically significant differences in cause-specific survival rates among stage III subgroups of T3N0, T1-2N1 and T3N1 (p = 0.0002). Our treatment method for patients with stage III mobile tongue squamous cell carcinoma was effective and acceptable.

Adult↗

Myositis ossificans following radical neck dissection.

Myositis ossificans traumatica is an uncommon disorder in which there is posttraumatic bone formation in muscle and other soft tissues near bone. The lesion is exceedingly rare in the head and neck. A case is presented in which myositis ossificans of the platysma occurred following radical neck dissection. Because recurrence may follow excision of the abnormal bone, removal is recommended only if there are significant symptoms associated with the lesion. If surgery is indicated, it should be delayed for 6 to 12 months following the initial trauma to allow for maturation of the lesion.

Aged↗

The sternomastoid branch of the occipital artery: a surgical landmark for the spinal accessory nerve in selective neck dissections.

OBJECTIVE: To evaluate the anatomic relationship between the spinal accessory nerve (SAN) and the sternomastoid branch of the occipital artery (SBOA) and its utility as a surgical landmark during a selective neck dissection (SND). STUDY DESIGN AND SETTINGS: Consecutive patients undergoing SND for squamous cancer from October 1, 2004 to February 28, 2005 were enrolled in this study. During surgery the distance between the SBOA and the point of insertion of the SAN into the sternomastoid muscle (SMM) was measured. RESULTS: Twenty-four patients underwent 33 SND. The distance between the SBOA and SAN ranged between 1 and 11 mm, with a mean of 6.2 mm and a median of 6 mm. CONCLUSION: The relationship between these 2 structures has a range and constancy that is acceptable as a landmark. SIGNIFICANCE: This article presents a useful adjunct for location of the SAN in the anterior neck during SND.

Accessory Nerve↗

Radical neck dissections for squamous carcinomas: pathological findings and their clinical implications with particular reference to transcapsular spread.

Two hundred fifty radical neck dissections, undertaken for mucosal squamous carcinomas of the head and neck, were reviewed with reference to pathological findings and their clinical implications. No major differences in descriptive surgical pathology were established between irradiated and non-irradiated resections. In general, irradiated dissections had lower total node counts and somewhat fewer nodal metastases involving a smaller number of different nodal groups. The topography of nodal deposits was similar in irradiated and non-irradiated resections. Palpable keratin granulomas (without intact tumor) were almost confined to irradiated patients. Transcapsular spread of tumor from involved lymph nodes was common: it was demonstrated in 160/188 'positive' dissections (85%) and was subclassified as 'macroscopic' in 90 and 'microscopic' in 70. The incidence and extent of transcapsular spread was similar in irradiated and nonirradiated resections. It was more frequently observed in association with large nodal masses but it was also regularly found with small nodal deposits less than 3 cm in diameter. Statistical analyses showed strong associations (p less than 0.0005) between the presence and/or extent of transcapsular spread and subsequent recurrence in the operated neck and overall survival. The predictive value of other clinical and pathological features vis-a-vis local neck recurrence such as numbers of involved nodal groups was weaker. Macroscopic transcapsulr spread emerges as the major prognostic factor for recurrent disease in the neck (p less than 0.0001). Attention is drawn to the advantages of accurate descriptive categories ('macroscopic', 'microscopic') for this critical prognostic feature.

Carcinoma, Squamous Cell↗

Aberrant central venous catheter complicating radical neck dissection.

Abnormal migration of central venous catheters is especially common in the case of long lines inserted via the antecubital fossa. A case is described of internal jugular vein migration of a central venous catheter complicating an ipsilateral radical neck dissection.

Catheterization, Central Venous↗

[Changes in blood flow velocity in the basal cerebral arteries following neck dissection].

Cerebral blood-flow velocities (cm/s) and pulse index (PI) were studied pre- and postoperatively in a total of 15 male patients following bilateral radical/functional (group A; n = 10) or unilateral radical neck dissection (group B; n = 5) using a 2 MHz-pulsed transcranial Doppler ultrasonographical system (TCD), with a transtemporal approach to the middle cerebral artery. Systolic and mean flow velocities were significant reduced with subsequent increases in PI during the first postoperative sonography in group A-patients while no significant differences in TCD date developed in group B. Blood-flow velocities and PI reached control values within three days. General hemodynamic and respiratory parameters did not influence the changes in TCD flow profiles with the exception of moderate increases in arterial CO2 during the early postoperative period. It is concluded that the reductions in blood-flow velocities and concomitant increases in PI reflect a heightened resistance to flow in the arterial cerebral vasculature. The decrease in cerebral vascular compliance suggests increases in the cerebral venous outflow following the resection of essential drainage pathways. However, TCD does not provide any information about the adequacy of cerebral blood flow.

Adult↗

Is a bilateral modified radical neck dissection beneficial for patients with papillary thyroid cancer?

PURPOSE: We previously reported a poor prognosis in papillary thyroid carcinoma patients with recurrence in the contralateral cervical lymph nodes after thyroidectomy and ipsilateral modified radical neck dissection (MRND) with a curative intent. The aim of this study was to investigate whether bilateral MRND improved prognosis in patients at risk for contralateral nodal recurrence. METHODS: We retrospectively reviewed the cases of 86 patients with contralateral nodal metastasis who underwent a thyroidectomy with bilateral MRND (group 1) and the cases of 32 patients who suffered contralateral nodal recurrence after a thyroidectomy with ipsilateral MRND (group 2). RESULTS: Although tumor progression was considered similar in patients from groups 1 and 2, group 1 developed fewer distant metastases than group 2 (6.8% vs 31.1%), thus resulting in a lower cancer death rate (5.8% vs 28.1%). Group 1 had a better 10-year survival rate than of group 2 (97.1% vs 83.7%). CONCLUSION: Bilateral MRND during initial surgical management is thus considered to improve the prognosis of some papillary carcinoma patients at risk for recurrence in the contralateral cervical lymph nodes.

Adult↗