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Results for “Maxillary Neoplasms”

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At least 631 records · Page 35Linked to original sources
PubMed2001

Clear cell odontogenic carcinoma: a clinicopathologic and immunocytochemical study of 5 cases.

CONTEXT: Odontogenic tumor composed predominantly of clear cells is a rare neoplasm of the jaws that was initially designated as clear cell odontogenic tumor. Subsequent reports in the literature, however, all have indicated that this tumor exhibits an aggressive behavior characterized by infiltrative local growth, recurrence, or metastases. OBJECTIVE: To ascertain the clinicomorphologic features and biologic behavior of this tumor group, we present 5 additional cases using the term clear cell odontogenic carcinoma. DESIGN: Histologic and immunohistochemical examinations were performed on clear cell odontogenic carcinomas from 5 patients. Clinical and follow-up data were recorded, and the literature was reviewed. RESULTS: The patients were 1 man and 4 women with an average age of 42.4 years at diagnosis. Three tumors occurred in the mandible and the other 2 in the maxilla. Four of the 5 cases occurred in the anterior or premolar areas of the jaws, appearing as poorly marginated radiolucencies. All cases consisted of islands and sheets of large clear cells and small basaloid cells with scanty eosinophilic cytoplasm, which were separated by thin, mature, fibrous septae. The tumors were unencapsulated and showed aggressive infiltration of the surrounding muscle and perineural tissues. Most of the clear cells contained cytoplasmic glycogen. Immunocytochemically, the tumor cells were positive for pan-keratin, cytokeratin 19, and epithelial membrane antigen, but were negative for vimentin, S100 protein, desmin, smooth muscle actin, human melanoma antigen (HMB-45), and alpha(1)-antichymotrypsin. Follow-up data showed 4 of 5 patients to have multiple local recurrences, and 1 of these 4 had submandibular lymph node metastasis and a fatal outcome due to uncontrollable tumor growth. CONCLUSION: These results suggest that odontogenic clear cell neoplasms are at least low-grade malignancies and should be classified as carcinomas.

Adenocarcinoma, Clear Cell↗
PubMedDate not supplied

Life table analysis and clinical evaluation of oral implants supporting prostheses after resection of malignant tumors.

Seventeen mostly elderly patients, 13 men and 4 women, were consecutively admitted for implant-prosthodontic treatment after they had undergone resection of malignant tumors in the oral cavity. A total of 53 dental implants (ITI-Straumann) was placed, 12 in the maxilla, 41 in the mandible. The prosthetic rehabilitation consisted of overdenture therapy in 15 patients, and 2 patients were treated with fixed partial prostheses. Thirty-three implants were prescribed for patients who received radiotherapy either before or after implant placement. The average dose varied between 50 and 74 Gy. Eighteen implants were located in grafted bone from the fibula, scapula, or hip. For 2 patients, hyperbaric oxygen therapy was also prescribed after osteoradionecrosis had developed. One implant was lost before prosthetic loading. During an observation period of up to 7 years after loading, 3 more implants were removed. All implant losses occurred in the mandibles of patients who had received radiotherapy. A life table analysis was performed, and the cumulative survival rates, calculated for 2, 3, and 5 years, were 93%, 90%, and 90% respectively. No failures or complications were observed with technical components of the implants or prostheses. All prostheses could be maintained during the entire observation time. Although in the present investigation the survival rate of implants was slightly lower than under standard conditions, the treatment with implant-supported prostheses seemed to be advantageous for patients who had undergone intraoral resections.

Adult↗
PubMed1975

Odontogenic myxofibroma: report of two cases.

We have reported the occurrence of two odontogenic mesenchymal tumors of the jaws. Though both cases had an associated impacted tooth, neither had foci of epithelial growth. Results of clinical, radiographic, and histopathological analysis in both cases were consistent with the diagnosis of a fibroma with myxomatous degeneration and thus, the diagnosis was myxofibroma.

Adolescent↗
PubMed1997

[The healing process of the temporalis myofascial flap in oral reconstruction].

From a prospective study of 36 patients having had temporalis myofascial flap (mean follow-up 32 months), the clinical oral healing process and the histological characteristics of the repaired mucosa were investigated. Among this group, 24 patients were assessed of the clinical scarring over the reconstructed area and 11 patients for histological evaluation of the repaired mucosa. Result showed that the uncovered temporalis myofascial flap in the mouth underwent a consistent healing commencing with an acute inflammatory phase, through chronic inflammatory and proliferative phases to eventual epithelialization by oral mucosa. No major complications affecting the healing flap were noted. The healed mucosa exhibited scarring in 70% of cases and the repaired mucosa demonstrated histological features distinct from the normal mucosa.

Adolescent↗
PubMed1997

[Ameloblastic carcinoma and malignant amelobastoma: histological reunderstanding].

Twenty-four cases of malignant ameloblastoma were reported, among them were nineteen cases followed up for 5 to 30 years. Histologic characteristics include predominated proliferation of the peripheral cells with papillary protruding to stroma, replacement of the stellate reticular cells in the follicular center by sarcomatous cells, as well as large and deep-stained or alveolar nuclei with moderate atypia, and high mitosis of the tumor cells. Clinico-radiologically, the tumor showed malignant features such as fast growing recently, pain, anesthesia, cauliflower ulcer, limited mouth opening, and large multilocular radiolucent area with ill-defined border. The biological behavior, nomenclature of the ameloblastic carcinoma or malignant ameloblastoma, and differential diagnosis from other tumors were also discussed.

Adolescent↗
PubMed1976

Metastatic chondrosarcoma to the maxilla: review of the literature and report of case.

Metastatic tumors to the jaw are relatively uncommon. When they occur, the primary tumor is most likely to be an adenocarcinoma from the breast, lung, or kidney. Metastatic tumors most frequently involve the mandible rather than the maxilla. The route of metastasis is considered hematogenous, although spread via lymphatic channels or the vertebral venous plexus may occur. An unusual instance of primary chondrosarcoma of the scapula metastasizing to the maxilla and to various soft tissue sites from tumor emboli, probably arising from an extensive metastatic lesion of the left atrium of the heart, has been presented.

Adult↗
PubMedDate not supplied

[Keratocysts].

Explore the source record for details and available documents.

Adolescent↗