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At least 631 records · Page 35Linked to original sources
PubMed2003

[Reliability and validity of Turkish version of magical ideation scale in university students].

OBJECTIVE: Schizoptypal disorder shares many clinical, neuropsychological and neurophysiological features with schizophrenia and is included in the schizophrenia spectrum. Patients with schizotypal disorder or individuals with mild schizotypal features are therefore highly valuable in the study of neuropsychological and neurophysiological characteristics of psychosis, and in particular schizophrenia, as they are likely to be free of the potential confounding factors of medication, chronic hospitalization and manifest psychosis. We report here the psychometric properties of the Turkish version of the Magical Ideation Scale (MIS), a self-report questionnaire that focuses on delusion-like beliefs and hallucination-like experiences and that has been used to quantify an important dimension of schizotypy. METHOD: Internal consistency and high cut-off scores were studied in 332 medical students. Forty-three students were readministered the scale 3 weeks later, and 96 received the Paranormal Belief Scale-R (PBS-R) along with the MIS, in order to measure test-retest reliability and convergent validity, respectively. RESULTS: The internal consistency of the scale is satisfactory with a Cronbach alpha coefficient of 0.78. Test-retest scores are highly correlated (r= 0.84). The high cut-off score is 21 for males, 23 for females, and 22 for the whole sample. Convergent validity was established by the significant correlation between the total MIS and PBS-R scores (r= 0.61). CONCLUSIONS: The scale is valid and reliable for studies that require a standard quantification of schizotypal signs and symptoms in young university students.

Adolescent↗
PubMed1992

Removing the "magic" from drugs.

Following training courses, young people in Sri Lanka are demonstrating that the subjective influence of alcohol and other drugs, and the behaviour they allegedly induce, can be changed by undermining widely held beliefs on their effects. Support is thus emerging for the view that the "magic" or pleasurable experiences commonly ascribed to drugs have little to do with their chemical action.

Adolescent↗
PubMed2003

[Disease and identity--a study of The magic mountain by Thomas Mann].

Disease is more than dysfunctional organs, morphological abnormalities and genetic divergence. It is also about existence, self-conception and social identity. Disease changes us as persons, but how this happens is usually not discussed in medical textbooks. However, literature appears to be rich in descriptions of these perspectives. This article explores The magic mountain by Thomas Mann to elucidate the relationship between personal identity and disease. I will argue that such knowledge is important to modern clinical practice.

Famous Persons↗
PubMed1992

[Experience with BALT magic catheter (PURSIL catheter); especially investigation about advantage, disadvantage and the applications].

BALT magic catheter (PURSIL catheter) is a new catheter which is more flexible and plaint than the TRACKER-18 catheter because its mid-section and distal portion are made from polyurethane and silicon rather than polyethylene. Because the PURSIL catheter is flexible, it cannot be inserted with a guide wire, although it can be inserted into circulation during injection of contrast medium. Its inner diameter, 3.5mm, is smaller than that (5mm) of the TRACKER. There are few reports of embolization with the PURSIL catheter, and these describe only embolization using adhesive liquid embolus material. Embolization using small particles through the PURSIL catheter has never been reported. We report the catheterization using the PURSIL catheter of 26 arteries in 15 patients. The catheter was used for superselective angiography to clarify feeder and amytal tests in 5 patients with AVM, and embolization using PVA particles (150-250 microns) was performed in 1 patient with AVM, 3 patients with dural AVM, 4 cases with meningioma and 1 patient with vertebral aneurysm. Small PVA particles were easily injected without resistance through this catheter. In only one patient with dural AVM, was catheterization with this catheter not successful, and that was because the distal portion of the internal maxillar artery was extremely tortuous because of severe atherosclerosis. No complications associated with the use of this catheter were observed. We think that the greatest advantage of this catheter is the safety afforded by not using a guide wire. A disadvantage of this catheter is that, because of its small inner diameter, only small particles, or liquid embolus material can be injected through it.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed2004

Bringing magic to the nursing workforce of the future.

How can nursing education respond to the ominous signs of a serious shortage of nurses in the future? One answer to this question is a focus on reclaiming nurses' stories of the "real-world" of nursing practice. In the process of creating a childrens book, The Magic Stethoscope, a group of nurse authors found a new appreciation for the stories of their practice and the need to share these stories with children. The authors hope that these stories will inspire children to consider the exciting career opportunities for the nursing workforce of the future.

Attitude to Health↗
PubMed2005

Liquid chromatography-mass spectrometric and liquid chromatography-tandem mass spectrometric determination of hallucinogenic indoles psilocin and psilocybin in "magic mushroom" samples.

Accurate and sensitive analytical methods for psilocin (PC) and psilocybin (PB), tryptamine-type hallucinogens contained in "magic mushrooms," were investigated using liquid chromatography-mass spectrometry (LC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS-MS). The chromatographic separation on an ODS column and mass spectral information gave complete discrimination between PC and PB without derivatization. The mass spectrometric detection had a high sensitivity, and the tandem mass spectrometric detection provided more specificity and accuracy, as well as high sensitivity. The detection limits ranged from 1 to 25 pg by LC-MS in the selected ion monitoring mode, and the intra- and inter-day coefficients of variation were estimated to be 4.21-5.93% by LC-MS-MS in the selected reaction monitoring mode. By applying the present LC-MS-MS technique to four real samples, the contents of PC and PB were found to vary over a wide range (0.60-1.4 and 0.18-3.8 mg/g dry wt. for PC and PB, respectively) between samples.

Agaricales↗
PubMed1992

An open letter to Magic Johnson.

The last installment in this series dealt with post-test counseling of a person whose HIV test was negative. The plan was to provide counseling for an HIV-infected person in this installment. NBA basketball star Magic Johnson's surprise announcement on November 7, 1991, of his infection with HIV has provided an unexpected opportunity to counsel a well-known person through an "open letter."

HIV Infections↗
PubMed1991

Characterization of cross-linking of cell walls of Bacillus subtilis by a combination of magic-angle spinning NMR and gas chromatography-mass spectrometry of both intact and hydrolyzed 13C- and 15N-labeled cell-wall peptidoglycan.

Cross-polarization magic-angle spinning 13C and 15N NMR, rotational-echo double resonance 13C NMR, and delays alternating with nutation for tailored excitation-difference 13C NMR spectra have been obtained from lyophilized cell walls of Bacillus subtilis grown on a synthetic medium containing D,L-[2-13C, 15N]aspartate and D-[1-13C]alanine. Label from aspartate is incorporated into D-glutamic acid and m-diaminopimelic acid of cell-wall peptidoglycan, while label from alanine appears in the C-1 positions of both D- and L-alanyl residues. The cross-link index (the fraction of peptide stems joined by an isopeptide covalent bond) is obtained directly from analysis of the results of the 13C NMR experiments. However, specific isotopic enrichments of cell-wall components cannot be obtained from NMR data alone. The latter are determined either from a gas chromatographic-mass spectrometric analysis of the amino acids derived from hydrolysis of cell-wall peptidoglycan, or from a combination of NMR and gas chromatographic-mass spectrometric results. The combined analysis is overdetermined and so involves the least error for evaluations of both the cross-link index and the isotopic enrichments. The cross-link index is 0.33 +/- 0.03 for cell walls of B. subtilis grown in the presence of the antibiotic, cephalothin.

Amino Acids↗
PubMed1990

Antibodies in diagnosis and therapy. The magic bullet--nearing the century mark.

A truly successful magic bullet therapy for cancer requires the production of agents which can easily reach, accurately recognize and permanently nullify every cancer cell in the body. Moreover, these precise functions must be achieved without adversely affecting normal vital tissues. This demanding approach is examined from the standpoint of animal model systems which satisfy these criteria to various extents. The salient features which contribute to success in these models are presented to provide a basis for evaluating the performance of currently available agents, and to assist in the design of new, more highly perfected 'bullets'. Pertinent issues regarding the therapeutic impact of cellular receptors, internalization pathways, mechanisms of toxin action, kinetics of cell killing, solid tumor penetration, pharmacokinetics and relative potency on target versus non-target cells are all considered. Current strategies using advanced biotechnical approaches to construct more effective targeted agents are addressed in this context.

Animals↗
PubMed1990

The MAGIC syndrome (mouth and genital ulcers with inflamed cartilage).

We describe a 42-year-old man with features of both Behçet's disease and relapsing polychondritis. The term MAGIC syndrome (mouth and genital ulcers with inflamed cartilage) has previously been used to describe similarly affected patients. We discuss the diagnostic criteria and pathogenetic mechanisms.

Adult↗
PubMed1989

[Placebo, culture and magic].

Modern medicine relays, as never before, on scientific foundations for its therapeutic endeavors. Nevertheless we detect a tremendous dissatisfaction among the people, a quasi irrational fear to ingesting medication in some, and a deterioration in the doctor-patient relationship. The placebo effect, the mainstay of this relationship is no longer favorable, in too many instances. This article defines the various types of placebo and very specially the negative placebo. It up-dates its concept, it reviews possible mechanisms of actions and undertakes an effort to place the placebo in its proper place in contemporary medicine. It also explores the cultural milieu and the undercurrent magical thinking since both of this provide the framework for the placebogenic phenomena.

Complementary Therapies↗
PubMed1983

Word magic revisited: monolingual and bilingual children's understanding of the word-object relationship.

We examined the claims that preschool children regard an object's name as being inseparable from its intrinsic properties and that bilingual children relinquish this notion earlier than monolingual children. 12 monolingual and 12 bilingual children of equivalent SES, nonverbal intelligence, talkativeness, and willingness to consider counterfactual situations were asked whether various objects could be renamed and then asked to identify objects by nonsense names and names for other objects. Virtually all the children performed the renaming tasks without error, and the monolinguals and bilinguals were equally likely to assent to renaming objects. However, monolinguals were more likely to mention an object's properties when justifying an answer, whereas bilinguals were more likely to mention the social context of the renaming act. These findings suggest that neither bilingual nor monolingual children are necessarily subject to "word magic"; rather, monolinguals have learned that an object can have more than 1 name by virtue of its various attributes, whereas bilingual children have learned, in addition, that an object can have more than 1 name by virtue of the different social contexts in which its name is used.

Child Development↗
PubMed1981

Estimation of protein turnover in soybean leaves using magic angle double cross-polarization nitrogen 15 nuclear magnetic resonance.

Magic angle cross-polarization 15N nuclear magnetic resonance spectra of intact lyophilized soybean leaves have been obtained at 9.12 MHz. The leaves were harvested over a 6-week period from 15N-uniformly labeled plants exposed to 13CO2 for 1 to 7 days. The concentration of 13C-15N double labels in the main chains of leaf protein was determined nondestructively by double cross-polarization techniques. Both incorporation and turnover rates of these double labels were estimated and together lead to the conclusion that the protein of a mature, fully expanded soybean leaf is fairly long lived, with a half-life of about 30 days.

Kinetics↗
PubMed1995

No magic bullets: a systematic review of 102 trials of interventions to improve professional practice.

OBJECTIVE: To determine the effectiveness of different types of interventions in improving health professional performance and health outcomes. DATA SOURCES: MEDLINE, SCISEARCH, CINAHL and the Research and Development Resource Base in CME were searched for trials of educational interventions in the health care professions published between 1970 and 1993 inclusive. STUDY SELECTION: Studies were selected if they provided objective measurements of health professional performance or health outcomes and employed random or quasi-random allocation methods in their study designs to assign individual subjects or groups. Interventions included such activities as conferences, outreach visits, the use of local opinion leaders, audit and feedback, and reminder systems. DATA EXTRACTION: Details extracted from the studies included the study design; the unit of allocation (e.g., patient, provider, practice, hospital); the characteristics of the targeted health care professionals, educational interventions and patients (when appropriate); and the main outcome measure. DATA SYNTHESIS: The inclusion criteria were met by 102 trials. Areas of behaviour change included general patient management, preventive services, prescribing practices, treatment of specific conditions such as hypertension or diabetes, and diagnostic service or hospital utilization. Dissemination-only strategies, such as conferences or the mailing of unsolicited materials, demonstrated little or no changes in health professional behaviour or health outcome when used alone. More complex interventions, such as the use of outreach visits or local opinion leaders, ranged from ineffective to highly effective but were most often moderately effective (resulting in reductions of 20% to 50% in the incidence of inappropriate performance). CONCLUSION: There are no "magic bullets" for improving the quality of health care, but there are a wide range of interventions available that, if used appropriately, could lead to important improvements in professional practice and patient outcomes.

Humans↗
PubMed1995

Harnessing the heightened public awareness of celebrity HIV disclosures: "Magic" and "Cookie" Johnson and HIV testing.

This article investigates the impact NBA basketball star Earvin ("Magic") Johnson's HIV disclosure had on changes in demand for HIV counseling and testing services in New York State's 61 Anonymous HIV Counseling and Testing sites. Interrupted time-series analyses were conducted on weekly data from over 34,000 clients seeking anonymous HIV counseling and testing services from January 1991 to June 1992, to determine whether demand for these services changed as a result of the disclosure. Results indicated that immediately following the HIV disclosure, there was a substantial increase in service demand, which transcended all sex, race, age, and most HIV risk-related boundaries. Seven months later, demand had not returned to pre-disclosure levels. The strong impact on females, coupled with additional data analyses in obstetrical settings, suggests that previous research has been too narrow in focus, and that the effect of Johnson's HIV disclosure has been enhanced, in part, by the publicity surrounding his wife and baby. The importance of harnessing the heightened public awareness of celebrity HIV disclosures is discussed.

AIDS Serodiagnosis↗
PubMed1994

Magic Johnson and public attitudes toward AIDS: a review of empirical findings.

The public announcement of HIV seropositivity and early professional retirement of basketball star Earvin "Magic" Johnson acted as a naturalistic experimental manipulation of media representations of persons living with HIV infection. This article reviews empirical studies of psychological and behavioral changes that occurred following the announcement. Several studies reported substantial increases in public interest in HIV/AIDS-related information and public awareness of AIDS, as well as changes in high-risk behaviors. Increases in calls to AIDS hotlines and increased rates of HIV antibody testing were also observed. However, most effects were short-lived, subsiding within three weeks of the announcement, and few changes in AIDS-related knowledge or personal risk perceptions were reported. Patterns of results indicated different levels of impact among high- and low-risk groups and among ethnic groups. Findings across studies are consistent with previous research on media effects on public attitudes and theories of risk perception.

Acquired Immunodeficiency Syndrome↗
PubMed1993

Sexual risk behaviors of STD clinic patients before and after Earvin "Magic" Johnson's HIV-infection announcement--Maryland, 1991-1992.

During the human immunodeficiency virus (HIV) epidemic, media and public interest have been captured periodically by accounts of persons infected with HIV. However, the effect of these stories on HIV/acquired immunodeficiency syndrome (AIDS) awareness and sexual behaviors is largely unknown. On November 7, 1991, Earvin "Magic" Johnson announced at a press conference he was infected with HIV and would be retiring from professional basketball. This report summarizes findings on the self-reported sexually transmitted disease (STD)/HIV sexual risk behaviors of patients of an STD clinic in a Maryland suburb of Washington, D.C., during the 14 weeks before and the 14 weeks after Johnson announced he was infected with HIV.

Adolescent↗