[The monitoring system for drip infusions].
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Telemedicine is gaining more and more momentum as a new approach for patients'surveillance. In many monitoring parameters, electrocardiography is the most important, especially for monitoring patients with serious cardiovascular diseases. They need to be monitored frequently in order to detect any deterioration. In this paper,we design a electrocardiographic telemetry system using General Packet Radio Service(GPRS). This design adds to traditional Holter capability of monitoring the patients'heart anywhere, anytime.
A toxicity evaluation is an important parameter in wastewater quality and in the monitoring of discharged effluents. Some organic and inorganic compounds at toxic levels have been detected in industrial discharges, resulting in plant upsets and discharge permit violations. In some cases, even though the effluent does not exceed the chemical-specific discharge limits, the results of toxicity tests show potential toxicity. Knowledge of the toxicity of effluents can benefit treatment plant operators in optimizing plant operation, protecting receiving water quality, and establishing sewer discharge permits. In the Turkish regulations only toxicity dilution factor with fish is part of the toxicity monitoring program of permissible wastewater discharge. This study investigated the acute toxicity of pulp-paper, leather, and petrochemical industry wastewaters by traditional and enrichment toxicity tests and emphasized the importance of toxicity tests in wastewater discharge regulations. The enrichment toxicity tests are novel applications indicating whether there is potential toxicity or stimulation conditions. Different organisms were used, including bacteria (Floc and Coliform bacteria) algae (Chlorella sp.), fish (Lepistes sp.), and protozoan species (Vorticella sp.) to represent four trophic levels. The toxicity test results were compared with chemical analyses to identify the pollutants responsible for the toxicity in the effluent wastewater samples. Toxicity of the effluents could not be explained by using physicochemical analyses in five cases for the leather and four cases for the pulp-paper and petrochemical industries. The results clearly showed that the use of bioassay tests produce additional information about the toxicity potential of industrial discharges and effluents.
This paper proposes a new process monitoring method using dynamic independent component analysis (ICA), ICA is a recently developed technique to extract the hidden factors that underlie sets of measurements, whereas principal component analysis (PCA) is a dimensionality reduction technique in terms of capturing the variance of the data. Its goal is to find a linear representation of non-Gaussian data so that the components are statistically independent. PCA aims at finding PCs that are uncorrelated and are linear combinations of the observed variables, while ICA is designed to separate the ICs that are independent and constitute the observed variables. The dynamic ICA monitoring method is applying ICA to the augmenting matrix with time-lagged variables. The dynamic monitoring method was applied to detect and monitor disturbances in a full-scale biological wastewater treatment (WWTP), which is characterized by a variety of dynamic and non-Gaussian characteristics. The dynamic ICA method showed more powerful monitoring performance on a WWTP application than the dynamic PCA method since it can extract source signals which are independent of time and cross-correlation of variables.
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In critically ill patients, the central nervous system remains vulnerable to multiple insults including ischemia, hemorrhagic events, and encephalopathy. The peripheral nervous system is vulnerable in the setting of neuro-muscular blockade (NMB), related drug-drug interactions, and drug-clinical state interactions. Optimal assessment of the nervous system is done by means of the clinical neurological examination. In this manner, orientation, arousal, and responsiveness to stimulation provide feedback on focal and global stability of the central nervous system. Where clinical evaluation is compromised, such as with deep sedation and NMB, risk of undetected seizure activity, and/or progression of neurological injury increases dramatically. A patient receiving NMB risks breakthrough awareness and pain. Long-term complications of NMB including prolonged weakness or paralysis as well as post-traumatic stress dramatically increase morbidity and length of stay. Technologies such as electroencephalogram (EEG) and bispectral index (BIS trade mark ) monitoring are effective for assessing cerebral function as well as level of sedation or arousal, respectively, in patients with a compromised neurological assessment. Neuromuscular transmission (NMT) monitoring by means of peripheral nerve stimulation and assessment of the evoked response may be utilized, within the context of clinical assessment, to determine level of chemical paralysis and minimize dosing of NMB agents. This article explores utilization and differentiates technologies such as EEG, BIS, and NMT monitoring. Monitoring parameters are illustrated using a case study approach.
The automated workplace (AWP) of anesthesiologist developed by the early 1990s provided data collection and processing, viewing of all monitors, and printing of anesthesiological chart (AC). AWP is a subject of continuous modification and adaptation to variable conditions. Computer monitoring including various measuring devises equipped with series interface RS-232 was implemented in Russian Research Center for Surgery. Rapid progress in computer network technologies made it necessary to adapt AWP to operation in computer networks. Since 1999 the computer network has been connected to the Internet. The use of computer technologies, including Internet, provides remote access to AC, thereby providing conditions for remote monitoring. AWP of anesthesiologist can be regarded as an automated control system of the patient state operated by anesthesiologist. Specific features of data processing in AWP are described. The AWP system is planed to be multiprocessor with distributed data flow. The suggested structure of computer network system for surgery rooms meeting the requirements of WWW-technology connected to the Internet is a promising approach to remote monitoring in medicine.
Human keratinocytes were cultured in serum-free medium for the purpose of on-line cell growth monitoring by image analysis. The validity of a process using a newly developed video microscopy system with image analysis for growth-rate monitoring in real time was verified by the measurement of the degree of confluence of keratinocytes in T-flasks and Petriperm dishes. The growth rate of keratinocytes was calculated subsequently from the linear relationship between average degree of confluence and cell concentration. This technique was applied to the culture in the bioreactor "KERATOR" in which a special video microscopy system using a CCD camera was built. The cell concentration evaluated by image analysis agreed well with that evaluated by conventional direct cell counting after enzymatic digestion, and the on-line monitoring of the specific growth rate allowed identification of both lag- and exponential-growth phases of the culture.
There are still many Oncomelania snails that inhabit the Kofu Basin, Yamanashi Prefecture, Japan, which had been declared free of schistosomiasis japonica. Due to the need to monitor the situation, a fixed-point observation system using GIS from GPS is being examined. In addition, in broad present or former endemic areas, survey areas are being managed by remote sensing with satellite images or aerial photographs. A simple and effective monitoring method by mobile GIS using PDAs was developed, risk or hazard maps were prepared and a system that would enable a response in the event of reemergence is being examined.
Alarms in the operating room remain a major source of annoyance and confusion. A previous study by Kestin et al. utilized a specific combination of distinct, separate monitors in 50 pediatric patients. He reported a mean of 10 alarms per case with a mean frequency of one alarm every 4.5 minutes. The alarms were classified as spurious (75%), change outside the alarm limits (22%), or patient risk (3%). We performed a similar study with 50 adult patients under general anesthesia with default alarm settings on an integrated monitor, (Cardiocap, Datex, Helsinki). In our study, the number of alarms averaged 3 per case with a mean frequency of one every 34 minutes. Spurious alarms (those caused by electrocautery, accidental patient movement, or other non-physiological reasons) represented only 24% of all alarms. Those alarms sounding that were outside the limits occurred at a rate of 53%, and those that were considered patient risks occurred at a rate of 23%. Of the alarms, 67% occurred during the beginning and end of anesthesia. The end-tidal carbon dioxide accounted for 42% of the alarms, mostly during intubation and extubation. Suggestions are made for further improvement in alarm systems.
OBJECTIVE: To compare measurement of cardiac output (CO) by means of the FloTrac CO monitor with the pulmonary artery catheter (PAC). DESIGN: Prospective observational study. SETTING: Intensive care unit of a tertiary hospital. PATIENTS: Six post-operative cardiac surgery patients with existing arterial cannulas and PACs. INTERVENTIONS: Attachment of the FloTrac CO monitor and transducer to an existing arterial cannula. Simultaneous measurements of CO, indexed to body surface area (cardiac index, CI) by the FloTrac CO monitor and by either a bolus thermodilution or continuous CO PAC. Statistical analysis of observations. MEASUREMENTS AND RESULTS: We performed CO measurements in six patients every 1-4 h after cardiac surgery. Comparison of all measurements showed a limited correlation for CI with the two devices (r (2)=0.1218, bias=0.21, 95% limits of agreement -0.81, 1.23). CI measurements obtained with the intermittent bolus PAC had better correlation with the FloTrac CI values (r (2) = 0.2693, bias=-0.0057, 95% limits of agreement -1.2042, 1.1929) than did those obtained with the continuous CO PAC (r (2)=0.0557, bias=0.2436, 95% limits of agreement -0.7350, 1.2222). When analysed according to heart rhythm, CI values measured during atrial pacing showed the best correlation (r (2)=0.377, bias=-0.0244, 95% limits of agreement -0.5226, 0.5714). CONCLUSIONS: CO measurements obtained using the FloTrac CO monitor show a limited correlation with those acquired using the PAC, relatively wide limits of agreement but no clear bias. Further evaluation is required before this device can be recommended for use in the clinical setting.
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