Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “MEXICO”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 631 records · Page 35Linked to original sources
PubMed1982

Seroconversion to Entamoeba histolytica among short-term travelers to Mexico.

Paired serum samples were evaluated for the presence of antibodies to Entamoeba histolytica in 326 healthy college students from the United States who lived in Guadalajara, Mexico, for an average of four weeks. One hundred eighty of these students had an enteric illness develop, but no stool test results were positive for ameba. An indirect hemagglutination assay was the serologic method used, and no seroconversion was demonstrates. This finding confirms the belief that amebiasis is a rare cause of diarrhea among short-term travelers to Mexico.

Antibodies, Bacterial↗
PubMed2003

Factors associated with poor mental health among Guatemalan refugees living in Mexico 20 years after civil conflict.

CONTEXT: From 1981 to 2001, 46 000 refugees who fled the 36-year civil conflict in Guatemala for Chiapas, Mexico were under the protection of the United Nations High Commissioner for Refugees. OBJECTIVES: To estimate the prevalence of mental illness and factors associated with poor mental health of underserved Guatemalan refugee communities located in Chiapas, Mexico, since 1981 and to assess need for mental health services. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional survey of 183 households in 5 Mayan refugee camps in Chiapas representing an estimated 1546 residents (adults and children) conducted November-December 2000. MAIN OUTCOME MEASURES: Symptom criteria of Posttraumatic Stress Disorder (PTSD), anxiety, and depression as measured by the Harvard Trauma Questionnaire and Hopkins Symptom Checklist-25 (Hopkins-25). RESULTS: One adult (aged > or =16 years) per household (n = 170 respondents) who agreed to participate was included in the analysis, representing an estimated 93% of households. All respondents reported experiencing at least 1 traumatic event with a mean of 8.3 traumatic events per individual. Of the respondents, 20 (11.8%) had all symptom criteria for PTSD. Of the 160 who completed the Hopkins Symptom Checklist-25, 87 (54.4%) had anxiety symptoms and 62 (38.8%) had symptoms of depression. Witnessing the disappearance of family members (adjusted odds ratio [AOR], 4.58; 95% confidence interval [CI], 1.35-15.50), being close to death (AOR, 4.19, 95% CI, 1.03-17.00), or living with 9 to 15 persons in the same home (AOR, 3.69; 95% CI, 1.19-11.39) were associated with symptoms of PTSD. There was a protective factor found for lacking sufficient food (AOR, 0.08; 95% CI, 0.01-0.59). Elevated anxiety symptoms were associated with witnessing a massacre (AOR, 10.63; 95% CI, 4.31-26.22), being wounded (AOR, 3.22; 95% CI, 0.95-10.89), and experiencing 7 to 12 traumatic events (AOR, 2.67; 95% CI, 1.14-6.27) and 13 to 19 traumatic events (AOR, 2.26; 95% CI, 0.65-7.89). Elevated symptoms of depression were associated with being a woman (AOR, 3.64; 95% CI, 1.47-9.04), being widowed (AOR, 27.55; 95% CI, 2.54-299.27), being married (AOR, 1.93; 95% CI, 0.59-6.33), witnessing disappearances (AOR, 2.68; 95% CI, 1.16-6.19), experiencing 7 to 12 traumatic events (AOR, 1.57; 95% CI, 0.64-3.88), or experiencing 13 to 19 traumatic events (AOR, 7.44; 95% CI, 2.18-25.37). CONCLUSION: Psychiatric morbidity related to human rights violations, traumatic events, and refugee status was common among Guatemalan refugees surveyed 20 years after the Guatemalan civil conflict.

Adult↗
PubMed1996

Nonmelanoma skin carcinoma in Albuquerque, New Mexico: experience of a major health care provider.

BACKGROUND: Although nonmelanoma skin carcinomas (NMSC) are increasing nationwide, rates are difficult to measure precisely, because few registries include types of carcinoma. Albuquerque, New Mexico is a high risk site for both melanoma and NMSC. In a National Cancer Institute (NCI) survey conducted between 1977 and 1978, NMSC incidence rates among non-Hispanic white males were the highest of 8 national study sites. METHODS: Experience with NMSC over 28.5 years at the Lovelace Health Systems in Albuquerque, New Mexico is described. The impact of multiple tumors was emphasized, recent annual incidence rates in members of the Lovelace Health Plan (LHP) were calculated, and trends in incidence rates since the NCI survey were estimated. RESULTS: There were 10,760 tumors among 4958 people between 1964 and mid-1992, with an average of 2.2 lesions per person (range: 1-92 lesions). Basal cell carcinoma (BCC) was 6.6 times more common than squamous cell carcinoma (SCC), and more likely to be multiple. There was an excess of males among persons with each tumor type and among subjects with multiple tumors. Only 46.1% of NMSC were first tumors; multiple or subsequent tumors comprised 53.7%. More than half of the concomitant or subsequent tumors were diagnosed within 1 year of the first, but new tumors were still appearing in the same subjects more than 10 years later. The incidence of NMSC between 1989 and 1991 among LHP members increased with age, and rates were higher for non-Hispanic males than females. Hispanics had much lower rates than non-Hispanic whites (NHW), with no sex differential. Incidence rates of BCC have increased markedly since 1977 and 1978 in NHW males, and to a lesser extent in other groups. Rates of SCC have not changed. The ratio of NMSC to other carcinomas at Lovelace has doubled over the same interval and has increased 10-fold over the last 2 decades. CONCLUSIONS: These data confirm the marked effect of age, ethnicity, and sex on NMSC rates. Differences in trends in BCC and SCC highlight their somewhat different etiologies. The increasing rate of BCC since the late 1970s and the large numbers of multiple tumors make a powerful case for intensified efforts at both primary and secondary prevention.

Adolescent↗
PubMed1998

Trends in the survival of American Indian, Hispanic, and Non-Hispanic white cancer patients in New Mexico and Arizona, 1969-1994.

BACKGROUND: The burden of cancer mortality falls disproportionately on cancer patients belonging to ethnic minority groups. In the U.S., African American, Hispanic, and American Indian cancer patients are diagnosed at a more advanced stage and receive less appropriate treatment, resulting in poorer outcomes and higher mortality, than white cancer patients. The authors hypothesized that cancer control strategies based on earlier detection and more effective treatment may be most effective in increasing survival in groups with more advanced disease at diagnosis, less appropriate treatment, and lower survival. METHODS: Data collected by the New Mexico Tumor Registry, a member organization of the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute, afforded the authors an opportunity to investigate this hypothesis by studying trends in cancer survival for American Indians, Hispanics, and non-Hispanic whites. The authors examined temporal trends and ethnic disparities in survival for in situ and invasive incident cancer cases at 25 sites diagnosed from 1969 through 1994 in New Mexico residents and in American Indians residing in Arizona. RESULTS: The distribution of stage became more favorable and the percentage of patients receiving appropriate treatment increased for all three ethnic groups during the study period. Survival improved for patients with cancer at most sites in each ethnic group; however, because the increase in survival was greater for non-Hispanic whites than for American Indians or Hispanics, the number of sites associated with disparities in survival among non-Hispanic whites, American Indians, and Hispanics increased. Differences in the distribution of age, gender, stage at diagnosis, histologic grade, and treatment did not completely explain the improved survival or the ethnic disparities regarding survival. CONCLUSIONS: Increased cancer control efforts were associated with earlier diagnosis, more patients receiving appropriate therapy, and improved survival for non-Hispanic whites, American Indians, and Hispanics. However, the improvement was greatest for non-Hispanic whites, and disparities in survival results for the different ethnic groups widened over the period of study. Cancer control strategies need to address the specific social, cultural, and biologic prognostic factors that affect different ethnic groups if disparities in outcomes are to be reduced.

Arizona↗
PubMed1998

Infection with CagA+ Helicobacter pylori strains as a possible predictor of risk in the development of gastric adenocarcinoma in Mexico.

Helicobacter pylori strains possessing the Cag pathogenicity island have been associated with increased gastric inflammation and with duodenal ulcer. In contrast, studies on the association of cagA+ H. pylori infections and gastric cancer have shown conflicting results. The aim of our study was to determine whether H. pylori and CagA status are associated with gastric cancer in Mexico. We selected serum samples from 3 geographic areas with gastric cancer mortality rates per 100,000 inhabitants of 2.5 (low risk), 4.5 (medium risk) and 6.4 (high risk). H. pylori infection was determined by the detection of antibodies to H. pylori whole cell antigen by an enzyme-linked immunosorbent assay (ELISA). To study the prevalence of infection with cagA+ strains, serum IgG antibodies to CagA were determined by ELISA using a recombinant CagA antigen. Of the 2,775 individuals studied, 1,931 were H. pylori seropositive and 1,710 had antibodies against CagA. The risk for gastric cancer in the 3 populations studied increased proportionally as infection with cagA+ strains increased (p < 0.001 for trend). H. pylori infection also showed association with gastric cancer (p < 0.05). Individuals seropositive for CagA, but seronegative for H. pylori whole cell antigen, were more frequent in areas with higher gastric cancer rates (p < 0.01). These results support the possible role of CagA(+) status as predictor of risk for gastric adenocarcinoma in Mexico; this is in agreement with results in European and American populations, but contrary to studies in some Asian countries.

Adenocarcinoma↗
PubMed1999

Nutrient intake and gastric cancer in Mexico.

In contrast to the decreasing trends observed in most countries, gastric-cancer mortality has remained at about the same level in Mexico throughout the last 40 years. As part of a study carried out in the metropolitan area of Mexico City, an assessment of nutrient intake and gastric cancer is presented here. The study population comprised 220 cases of gastric cancer and 752 population-based controls. Our results showed 70 to 80% reduction in the risk of developing this tumor, associated with the intake of polyunsaturated fat, fiber and vitamin E; and this effect was independent of the histological type of the tumor (i.e., intestinal or diffuse). On the other hand, an increased risk of gastric cancer was related to the consumption of saturated fat (OR(Q4vs.Q1) = 4.37, 95% CI 1.89-10.12) and, cholesterol (OR(Q4vs.Q1) = 2.39, 95% CI 1.23-4.64), but such effects were restricted to the intestinal type of gastric cancer. In the whole study population, mono-unsaturated fat intake increased the risk for gastric cancer, and a marginally significant increasing trend was observed for protein consumption. The findings from this study add information about the role of specific nutrients in the etiology of gastric cancer.

Adult↗
PubMed1997

Back to the future: sweatshop conditions on the Mexico-U.S. border. II. Occupational health impact of maquiladora industrial activity.

Present working conditions in one of the most active areas of the maquiladora system along the Mexico-U.S. border are reminiscent of nineteenth-century U.S. sweatshops. The organization of production is Tayloristic and authoritarian, with detailed division of labor, repetitive simple tasks, and piecework wages. Modern participative management styles are not apparent in the maquiladora setting. This study consists of two separate but interrelated surveys conducted in 1992, one of community leaders and this one of workers in maquiladora enterprises in the towns of Matamoros and Reynosa, Mexico. The community survey evaluated the economic and psychosocial impact of the maquiladora enterprise and was conducted simultaneously to the workers' survey and in the same Mexican towns where the workers lived and worked. The community leaders acknowledged the employment opportunities that maquiladora factories had brought to the region but believed them to have high environmental and psychosocial costs. For the occupational component, a community-based survey of 267 maquiladora workers was conducted. participants were chosen with more than a year seniority in the industry and living in the two Mexican cities surveyed. They responded to an extensive questionnaire given by trained canvassers. The workers' survey found evidence that maquiladora workers (81% female) report symptoms from musculoskeletal disorders related to working conditions. Acute health effects compatible with chemical exposures were also identified. Prevalence of symptoms was correlated with increasing duration of exposure to ergonomic risk factors and qualitative chemical exposure indexes. Other chronic disease was not apparent. The survey demonstrated inequalities in salary, working hours, and safety training between the two communities. Matamoros workers are substantially better paid and work fewer hours per week than Reynosa workers. Most hazards reported in the worker's survey have been well studied in the general occupational health literature with respect to adverse health effects. Therefore, it is recommended that hazard surveillance studies would be more useful towards the goal of prevention than further etiologic studies. Specific recommendations on policy and remediation interventions are also made.

Adult↗
PubMed1978

Gallbladder disease and gallbladder cancer among American Indians in tricultural New Mexico.

Previous studies have reported high rates of gallbladder disease and gallbladder cancer among all American Indians. Data from the New Mexico Tumor Registry confirm these findings, specifically showing high rates for New Mexico's American Indians, as well as for the state's Spanish population. This review explores several risk factors, including parity, obesity, age, cholesterol level, and genetic factors. From the available evidence, genetic factors appear to be the most important, with parity a contributing factor.

Epidemiologic Methods↗
PubMed1982

Malignant melanoma of the skin in New Mexico 1969-1977.

We assessed the occurrence of malignant melanoma of the skin in New Mexico from 1969-1977. Incidence data, collected by the New Mexico Tumor Registry, were supplemented with mortality data supplied by the State Bureau of Vital Statistics. These data were analyzed for variation by site, sex, and ethnic group. Malignant melanoma occurrence varied with ethnicity. Incidence rates for non-Hispanic whites (Anglos) exceeded comparison US rates, and were approximately six times higher than for other ethnic groups. Annual incidence rates for Hispanics, American Indians, and blacks of both sexes ranged from 0.0-1.8 cases per 100,000. As anticipated from other studies, the lower extremities were the most common site in Anglo women, and the trunk was the most common site in Anglo men. In contrast, the trunk was the most common site for both Hispanic men and women. A statistically significant trend of increasing incidence was demonstrated only for the Anglo women. Mortality rates varied widely during the study period and did not correlate with incidence rates.

Adolescent↗
PubMed1995

Hodgkin's disease in Mexico. Prevalence of Epstein-Barr virus sequences and correlations with histologic subtype.

BACKGROUND: The Epstein-Barr virus (EBV) has been linked to several human malignancies, including Hodgkin's disease (HD). In addition, epidemiologic studies have shown differences in HD occurrence in different parts of the world. The authors studied 27 cases of Hodgkin's disease from Mexico to determine the prevalence of EBV in HD in this developing nation. METHODS: The Epstein-Barr virus was investigated using in situ hybridization with the EBER1 probe. Immunohistochemical studies were performed on paraffin sections. Cases from both adult and pediatric age groups were included. Correlations with histologic subtype, clinicopathologic features, and immunophenotype were determined. RESULTS: Epstein-Barr virus sequences were identified in 18/27 (67%) cases. Positivity correlated with histologic subtype: 0/1 lymphocyte predominant; 6/13 (46%) nodular sclerosis; 7/7 mixed cellularity (MC) (100%); and 5/6 (83%) lymphocyte depleted (LD). The proportion of cases classified as MC and LD (13 of 27) was greater than that found in the United States and other developed countries. The immunophenotypic profile was appropriate for Hodgkin's disease, with all cases of classic Hodgkin's disease positive for CD30 (Ber-H2) and 18 cases expressing CD15. One case of lymphocyte-predominant Hodgkin's disease was CD20 (L26)-positive as were three cases of classic Hodgkin's disease. Patient age ranged from 5 to 65 years, with a median of 29 years. CONCLUSIONS: The EBV is associated highly with HD in Mexico, and this prevalence rate is found in all age groups. A strong correlation between EBV expression and histologic subtype was confirmed, with 92% of MC and LD subtypes found to be positive.

Adolescent↗
PubMed1977

Franz Boas and his plans for an International School of American Archaeology and Ethnology in Mexico.

The expansionist policy of the United States at the turn of the century widened the horizons of American anthropology. The International School of American Archaeology and Ethnology was one of the first attempts by American anthropologists to carry out systematic research in foreign lands. Motivated partly by a wish to strengthen the quality of American anthropology, Franz Boas succeeded in gaining the cooperation of several European and American institutions. The purpose of the school was to conduct rigorous anthropological investigations in Mexico. Obsessed with professionalizing the discipline, Boas failed to take into account the turbulent political climate of Mexico when planning the school. Although it did good work for a number of years (1910-1914), the school was broken up forever in 1914 because of the Mexican revolution. Attempts at resurrection failed for numerous reasons.

Anthropology, Cultural↗
PubMed2002

Juvenile myoclonic epilepsy: linkage to chromosome 6p12 in Mexico families.

Juvenile myoclonic epilepsy is a common subtype of idiopathic epilepsy accounting for 4-11% of all epilepsies. We reported previously significant evidence of linkage between chromosome 6p12-11 microsatellites and the clinical epilepsy and EEG traits of JME families from Belize and Los Angeles. To narrow the JME region, we ascertained and genotyped 31 new JME families from Mexico using a later generation of Généthon microsatellites. Two point linkage analyses obtained significant Z(max) values of 3.70 for D6S1573 and 2.65 for D6S1714 at theta(m = f) = 0.10, and 3.49 for D6S465, 2.11 for D6S1960 at theta(m = f) = 0.05 assuming autosomal dominant inheritance with 70% age-dependent penetrance. Multipoint LOD score curve peaked at 4.21 for D6S1573. Haplotype and recombination analysis reduced the JME region to 3.5 cM flanked by D6S272 and D6S1573. These results provide confirmatory evidence that a major susceptibility gene for JME exists in chromosome 6p12 in Spanish-Amerinds of Mexico.

Chromosome Mapping↗
PubMed1986

Gene frequencies and admixture estimates in a Mexico City population.

Five hundred and ten students of the Universidad Nacional Autónoma de México were tested to determine the distribution of ABO, MN, Rr-Hr blood groups, and serum haptoglobin, albumin, and Factor Bf types. Based on the results we found that the proportion of Indian and White genes are of 56.16 and 43.84%, respectively in the dihybrid model and 2.93, 56.22, and 40.85% for Blacks, Indians, and Whites in the trihybrid one. The present study reveals a higher proportion of Indian genes in the Mexico City population than estimated in previous publications. Reasons why the present results apply to a much larger group of Mexico City mestizos than the previous ones are given.

ABO Blood-Group System↗
PubMed1987

Adaptive significance of small body size: strength and motor performance of school children in Mexico and Papua New Guinea.

The postulated superior functional efficiency in association with reduced body size under conditions of chronic protein-energy undernutrition was considered in school children from rural Mexico and coastal Papua New Guinea. Grip strength and three measures of motor performance were measured in cross-sectional samples of children 6-16 years of age from a rural agricultural community in Oaxaca, Mexico, and from the coastal community Pere on Manus Island, Papua New Guinea. The strength and performance of a mixed-longitudinal sample of well nourished children from Philadelphia was used as a reference. The Oaxaca and Pere children are significantly shorter and lighter and are not as strong as the well nourished children. Motor performances of Pere children compare favorably to those of the better-nourished Philadelphia children, whereas those of the Oaxaca children are poorer. Throwing performance is more variable. When expressed relative to body size, strength is similar in the three samples, but the running and jumping performances of Pere children per unit body size are better than the relative performances of Oaxaca and Philadelphia children. Throwing performance per unit body size is better in the undernourished children. The influence of age, stature, and weight on the performance of Oaxaca and Pere children is generally similar to that for well nourished children. These results suggest that the hypothesized adaptive significance of small body size for the functional efficiency of populations living under conditions of chronic undernutrition varies between populations and with performance tasks.

Adolescent↗
PubMed2005

Admixture analysis of a rural population of the state of Guerrero, Mexico.

We studied 156 individuals of Native American descent from the city of Tlapa in the state of Guerrero in western Mexico. Most individuals' ethnicity was either Nahua, Mixtec, or Tlapanec, but self-identified Mestizos and individuals of mixed ethnicities were also included in the sample. We typed 24 autosomal, one Y-chromosome, and four mitochondrial ancestry-informative markers (AIMs) to estimate group and individual admixture proportions, and determine whether the admixture process involved directional gene flow between parental groups. When genetically defined (GD) Mestizos were excluded from the analysis, Native American ancestry represented approximately 98% of the population's gene pool, while European and West African ancestry represented approximately 1% each. Maternally inherited markers also showed an exceptionally high Native American contribution (98.5%), as did the paternally inherited marker, DYS199 (90.7%). We did not detect genetic structure in this population using these AIMs, which appears consistent with the homogeneity of the sample in terms of admixture proportions. The addition of GD Mestizos to the sample did not produce a considerable change in admixture estimates, but it had a major effect on population structure. These results show that the population of Tlapa in Guerrero, Mexico, has experienced little admixture with Europeans and/or West Africans. They also show that the impact of a small number of admixed individuals on an otherwise homogeneous population might have profound implications on subsequent ancestry/phenotype analysis and mapping strategies. We suggest that heterogeneity is a major characteristic of Mexican populations and, as a consequence, should not be disregarded when designing epidemiological studies of Mexican and Mexican American populations.

Black People↗
PubMed2004

Prevalence of craniorachischisis in a Texas-Mexico border population.

BACKGROUND: The most severe neural tube defect (NTD), craniorachischisis, is characterized by anencephaly confluent with spina bifida open from the cervical to the lumbar region. We describe the prevalence of craniorachischisis among the Texas-Mexico border population during the period 1993-1999. METHODS: An active surveillance system identified all clinically apparent NTD-affected fetuses and infants born to mothers residing and delivering in any of the 14 Texas-Mexico border counties. Craniorachischisis cases included live-born, stillborn, and therapeutic abortions. RESULTS: A total of 16 craniorachischisis cases were identified for a total prevalence of 0.51 per 10,000 live births (Mexican American prevalence, 0.52 per 10,000) and a prevalence of 0.28 per 10,000 live births for cases of 20 weeks gestation or greater. CONCLUSIONS: The prevalence of craniorachischisis was higher than that reported in Atlanta (0.1 per 10,000 live births), but much lower than that reported in Northern China (10.7 per 10,000 births). In this high NTD prevalence region, it is possible that a multiplicity of risk factors, mostly related to poverty, contribute to a high prevalence of craniorachischisis.

Black or African American↗
PubMed1994

Quality control study on negative gynecological cytology in Mexico.

An external evaluation of the quality of diagnosis of gynecological cytology specimens (Papanicolaou or "Pap" tests) in the Cytopathological Laboratory at the Mexico General Hospital was performed, with evaluation of 6,011 Pap tests randomly selected from 31,378 Pap studies previously reported as negative during 1988-1989. These tests were part of the early detection program for cervical cancer run by the Ministry of Health of Mexico City. A quality index for specimens was constructed based on the presence of endocervical cells, mucus, and squamous metaplastic cells. The index of false negatives for the diagnosis of cervical neoplasm in this sample which correspond to diagnostic error by the examiner was 0.18% (11). The constructed quality index revealed that 64.1% of specimens were low quality. The correlation between diagnostic error and low quality was .87. Results indicate that laboratories participating in early detection programs for cervical cancer in developing countries need to implement (1) external evaluation programs for Pap diagnosis; (2) permanent training programs in registration; and (3) monitoring procedures for collection, fixation, and transportation of cytologic materials.

Adolescent↗
PubMed2004

Risk factors for squamous intraepithelial lesions (SIL) of the cervix among women residing at the US-Mexico border.

It is now well established that cervical cancer is caused by oncogenic human papillomavirus (HPV) infections that commonly infect women worldwide. What remains to be understood are the factors that contribute to cervical cancer in the presence of HPV infection. We conducted a case-control analysis of women recruited at the US-Mexico border to simultaneously evaluate factors associated with 3 cytologic outcomes: atypical squamous cells of undetermined significance or atypical glandular cells of undetermined significance (ASCUS/AGUS), low grade squamous intraepithelial lesions (LSIL) and high grade squamous intraepithelial lesions (HSIL). A cross-sectional binational study of 2059 women ages 15-79 years was conducted between 1997 and 1998. A significant difference in the distribution of cytologic categories by country was observed (3.0% vs. 0.7% HSIL among Mexican vs. US women, respectively). The only factors independently associated with all 3 cytologic outcomes were HPV infection and viral load. A linear increase in risk with increasing viral load was observed for each of the 3 outcome variables, with the strength of this association increasing with cytology abnormality. In addition to HPV infection, parity and Mexico as a country of residence appear to be associated with LSIL and HSIL, respectively. Factors associated with cytologic outcomes in analyses limited to women with HPV infection were similar to results obtained in models where HPV infection was included as a covariate. Future work is needed to evaluate the predictive value of HPV viral load utilizing more specific and quantitative measures.

Adolescent↗