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Comparison of cytocidal and noncytocidal strains of Shope rabbit fibroma virus.

Seven strains of Shope fibroma virus were compared for their effect on rabbit cells in vitro. All but one of the naturally occurring strains examined in this study produced a similar response in the infected cultures. This consisted of continued cell multiplication together with changes in cell morphology and growth pattern. In contrast, a recently isolated strain of fibroma virus, the M1 strain, was found to produce a gradual cell destruction under the same cultural conditions. A comparison of the cytocidal M1 strain with a representative noncytocidal strain in vitro showed no differences in the rate of multiplication, plaque type, antigenic composition, or heat lability. Only minor differences were found in the tumors produced in rabbits by these strains.

Animals↗

Chondromyxoid fibroma: report of three cases with predominant cortical involvement.

The clinicoradiologic and pathologic aspects of three cases of chondromyxoid fibroma of small size and predominant cortical location are reported. Because of these unusual features, the possibility of chondromyxoid fibroma was not considered on the basis of the radiographic pattern. The diagnosis was made after pathologic examination of the tissue, obtained in two cases via needle biopsy, which led to the appropriate treatment, en bloc excision.

Adolescent↗

Chondromyxoid fibroma of the nasal septum: a case report emphasizing clinical correlation.

Chondromyxoid fibromas are uncommon tumors most often seen in long bones of adolescent and young males. Involvement of craniofacial bones is extremely unusual, with sporadic case reports described in the literature. We describe the first case of chondromyxoid fibroma arising in the nasal septum with local destruction and expansile growth into the ethmoid bone and inferior turbinate in a 60-year-old female. The fortuitous discovery of this otherwise asymptomatic lesion and its follow-up are detailed. The literature is reviewed and salient clinical, radiographic, and pathologic correlative findings are emphasized.

Chondroblastoma↗

Chondromyxoid fibroma of the femur: a case report with intra-cortical location.

Chondromyxoid fibroma (CMF) is the least common benign cartilaginous tumor, comprising less than 0.5 to 1% of all skeletal neoplasms. This subject was a 16-year-old female with a three-year history of pain involving the distal femoral metaphysis. This case showed an unusual feature: it was intracortical in location. Radiologic differential diagnosis included metaphyseal fibrous defect, periosteal chondroma, simple or aneurysmal bone cyst, and cortical abscess. On operation, the lesion filled the intracortical defect with whitish myxoid soft tissue, bulging into the adjacent soft tissue. Microscopically, it showed typical features of chondromyxoid fibroma composed of mainly myxoid nodules and peripheral fibrous elements with focal chondroid differentiation.

Adolescent↗

Chondromyxoid fibroma of a metatarsal and cuneiform.

The occurrence of chondromyxoid fibroma in the foot is relatively rare, and it is highly unusual for the lesion to involve the epiphysis. The authors report a case of a highly aggressive tumor occurring in the first metatarsal bone, crossing the epiphysis and invading the medial cuneiform bone. A literature search did not reveal previous cases of chondromyxoid fibroma in this unusual location.

Adult↗

Chondromyxoid fibroma of the scapula associated with aneurysmal bone cyst.

A rare case of chondromyxoid fibroma of the scapula in a 21-year-old man is presented. This case is of interest because of its unusual site and association of aneurysmal bone cyst. Although chondromyxoid fibroma is uncommon bone tumor of the scapula, it should be considered in the differential diagnosis of expansile osteolytic lesion of the scapula.

Adult↗

Malignant degeneration of a chondromyxoid fibroma in a child.

A 10-year-old boy was treated for a chondromyxoid fibroma of the left femur by curettage, and 2 months later complete healing was demonstrated radiographically. Three years after operation, radiographs revealed replacement of the ilium, ischium and upper femur, and destruction of the left hip by a soft-tissue and bony mass; a left hemipelvectomy was performed for what was shown to be a chondrosarcoma. Follow-up 10 years after the initial operation and 7 years after the hemipelvectomy has confirmed uneventful recovery in this rare case of malignant degeneration of a proven chondromyxoid fibroma of bone.

Adolescent↗

Central odontogenic fibroma--report of a case and review of the literature.

A case of a central odontogenic fibroma involving the left mandible of a 39-year-old female is presented. The clinical and radiographic appearance, surgical treatment, and histopathologic diagnosis are discussed. With the addition of this case, a total of 68 cases of central odontogenic fibroma have thus far been reported in the English language literature.

Adult↗

Multiple dermal perifollicular fibromas with polyps of the colon -- report of a peculiar clinical syndrome.

In the present study, a peculiar fibromatosis cutis in two siblings has been reported, the dermatosis being characterized by innumerable perifollicular fibromas on face, neck and trunk as well as multiple fibromata pendulantia. Since the father allegedly had skin lesions resembling those of his two affected children, an inherited condition is assumed for the disease which manifests itself rather late in age. In the female patient, several adenomatous colon polyps were found, one transformed into an incipient carcinoma. Since the clinical and dermatohistological features are anything but typical of Gardner's syndrome and, in particular, hamartomalike fibromas of the perifollicular hair sheath are not constituents of its well-known skin tumour complex, we have discussed in detail the possibility of a peculiar cutaneo-intestinal syndrome hitherto unknown.

Adult↗

Chondromyxoid fibroma: a study based on 18 cases.

The authors report on 18 cases of chondromyxoid fibroma seen at the Institute of Orthopedics and Traumatology, University of São Paulo, from 1953 to 1990. A survey of the literature on chondromyxoid fibromas was conducted and radiographic analysis of all cases is presented, with a mean follow-up of 64 months. The surgical treatment employed in each case is discussed, with emphasis on the use of cement as an adjuvant. This procedure was used in 10 patients, who have been free of recurrence up to the present time.

Adolescent↗

Cementifying fibroma diagnosed by fine needle aspiration cytology. A case report.

A case of cementifying fibroma in the right lateral mandible was diagnosed by fine needle aspiration (FNA) cytology. The aspirate was a cellular specimen composed of clusters of oval and spindle-shaped fibroblasts with no atypical features. These cells were admixed with spherical, calcified structures. A diagnosis of "consistent with benign fibroosseous lesion, suggestive of cementoossifying fibroma" was made, and subsequent histologic examination confirmed this cytologic diagnosis. The clinical, cytologic and histologic findings in the case are presented, and the value of FNA cytology in the diagnosis of jaw lesions is discussed.

Adult↗

Cemento-ossifying fibroma: a case report.

Cemento-ossifying fibroma is a mesodermal, slow-growing, benign fibro-osseous lesion of the jaws. A case of mandibular molar enlargement that was treated previously by other surgeons and diagnosed as cemento-ossifying fibroma, is presented. Two recurrences occurred 4 and 8 years after surgery due to incomplete surgical removal.

Adult↗

Cemento ossifying fibroma.

Cemento ossifying fibroma is a benign, non odontogenic tumour of the jaw, a subdivision of fibro-osseous lesions. The age of occurrence is between 20 and 40 years. It has a female to male predilection of 2:1. A rare case of cemento ossifying fibroma involving maxilla and mandible in a 30 years old female is presented with a discussion on its clinical and radiographical features, computed tomograph scan findings, histopathological presentation with a review of literature.

Adult↗

[A rare case of chondromyxoid fibroma of the parietal bone].

The authors present a very rare case of the chondromyxoid fibroma (CMF) of the parietal bone. This is an uncommon chondroid tumour which constitutes less than 1% of primary bone tumours and which is usually localised in the metaphysis of the long bones, often in the knee region. There are 23 cases of cranial localisation of the chondromyxoid fibroma reported in several papers, 14 cases involved the cranial base and 9 the calvaria. A different ossification process of the skull-base and calvaria is probably responsible for this distribution. In our case we found the focal, lytic lesion in the parietal bone and fibro-greasy tumour mass. The dura was spared. The tumour was removed totally. Curettage of these kind of lesions should be avoided because it may lead to tumour recurrence. Histologically this tumour may cause problems in a differential diagnosis with other chondroid tumours like chondrosarcoma or chondroblastoma.

Adult↗

Ameloblastic fibroma. Report of a case with fine needle aspiration cytologic findings.

A case of ameloblastic fibroma of the jaw in an 18-year-old patient is presented. Fine needle aspiration cytologic smears showed two different types of cellular elements: a glandlike epithelial component, arranged in bidimensional, well-outlined clusters of basaloid cells with palisading of the columnar cells at the borders of those clusters, and a mesenchymal component that consisted of loosely arranged fusiform cells. These cytologic features appear to be sufficiently characteristic to suggest a diagnosis of ameloblastic fibroma by fine needle aspiration.

Adolescent↗

[Nasopharyngeal fibroma. Forms extended to the infratemporal fossa].

There are two clinicopathologic forms of nasopharyngeal fibroma: a median, compact form for which surgical treatment is simple, and a racemose, pedicled form raising problems for exeresis due to its extensions into the infratemporal fossa and the middle cranial fossa. A 4-stage grading is essential, and it has become easier with the progress made by imaging. The clinical findings, the contribution of imaging and the surgical procedures are studied for stages III and IV. Statistics are presented for 26 nasopharyngeal fibromas, including 10 invasive forms. Two approaches of the infratemporal fossa have been used in this series; the PLN approach with a large fronto-naso-maxillary flap, and the pre-auricular infratemporal lateral approach. The exeresis of stage III lesions requires the lateral approach.

Adolescent↗

[The ameloblastic fibroma. An odontogenic tumor in the growth period].

Nine cases of ameloblastic fibroma are described and compared with published data on this odontogenic tumour. The median age of the 7 male and 2 female patients was 11 years (range 2-17 yrs.). The tumour was localized in the posterior segment of the mandible and less often in the maxilla. The neoplasia was frequently associated with impaction and agenesis of teeth. Although recurrences of ameloblastic fibromas are rare, long-term follow-up is recommended.

Adolescent↗

[Chondromyxoid fibroma of the cervical spine. Apropos of a case treated by partial vertebrectomy].

A case of chondromyxoid fibroma revelated by cervicalgias and involving the right part of the 5th cervical vertebra is reported. This uncommon cartilaginous tumor is usually described in the metaphysis of long bones and appears very rare in the spine. If radiological aspects have been reported, the majors series do not describe a typical appearance of vertebral lesions; our patient is one of the first to have been evaluated by CT scan. Chondromyxoid fibromas are benign tumors, but recurrence is possible especially when treated by curettage alone. In our case, operated on two stages, the resection seemed sufficiently large and CT control on the 10th month did not show evidence of recurrence. Clinical and radiologic findings, and surgical management of these vertebral tumors are discussed.

Adult↗