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At least 631 records · Page 35Linked to original sources
PubMed2006

Orf virus infection in humans--New York, Illinois, California, and Tennessee, 2004-2005.

Orf virus is a zoonotic parapoxvirus endemic to most countries in the world and is principally associated with small ruminants (e.g., sheep and goats). Human orf infections appear as ulcerative skin lesions after contact with an infected animal or contaminated fomite. This report summarizes the epidemiologic and laboratory investigations of four sporadic cases of human orf infection, emphasizing the temporal association between human lesions and skin trauma or recent flock vaccination with live orf vaccine. This zoonotic infection shares clinical manifestations and exposure risks with other, potentially life-threatening zoonoses (e.g., cutaneous anthrax) and is likely under-recognized because of a lack of clinical suspicion and widely available diagnostics. Barrier precautions and proper hand hygiene are recommended for the prevention of orf virus infection in humans.

Adolescent↗
PubMedDate not supplied

Two giant orf lesions in a heart/lung transplant patient.

Orf is an infectious ulcerative stomatitis of sheep and goats. The responsible pathogen, parapoxvirus, may be transmitted to humans. Orf lesions are often atypical in immunocompromised individuals. The present report describes two very large exophytic lesions in a 31-year-old transplant patient receiving oral tacrolimus, mycophenolate mofetil and prednisone. Early surgical excision was successful, with no relapse after 14 months.

Adult↗
PubMedDate not supplied

[The role of persistence and virulence factors in microecological changes in a humans].

The patterns of persistence and virulence factors expression in the representatives of human microbial biocenosis depends on a complex of the environmental conditions: influence of microbes-symbionts, biotope peculiarities, properties of microorganisms located within eukaryotes. Interactions of symbionts in pairs "indigen-indigen" isolated from mucous membrane of tonsils in healthy persons, did not lead to changes in expression of pathogenic properties. Interinfluence in pairs "pathogen-indigen" and "indigen-indigen", isolated from patients with chronic tonsilitis were accompanied by an increase of anti-lysozyme, hemolytic and lecithovitellase activities. Migration of strains of non-enzymatized gram-negative bacteria (NEYNB) from nasal into tympanic cavity in experimental acute purulent otitis is connected with an earlier increase of their number in the nasal cavity and the expression of anti-lysozyme activity. In acute and chronic pyoderma, expression of ALA is more marked in bacteria from a perifocal damage in contrast to focal damage of normal skin. In conditions of interaction between erythrocytes and staphylococcal clones with different levels of expression of pathogenic factors, differences were observed in dynamics of hemolytic and anti-hemoglobin activities.

Animals↗
PubMed1991

Soremouth in sheep and goats at the Mankon Animal Research Station, Cameroon.

Between 1980 and 1989, a survey was carried out to appreciate the prevalence of the soremouth (orf) disease among sheep and goat flocks at the Mankon Research Station (Cameroon). The results showed that orf is enzootic at the station and is more a goat (85.5%) than a sheep disease (51%) with kids showing a higher susceptibility rate (53%) than adult goats. Orf has a high mortality (80-90%) with a negligible mortality rate (2%). Both sexes were affected while more incidences of orf were recorded during the dry season than in the rainy season.

Animals↗
PubMed1991

Orf infection following ear tagging in goats.

This communication describes the first record of orf infection in goats following ear-tagging. Typical orf lesions were observed in the affected goats, and the virus was reisolated and identified from them. The threat of orf infection following ear-tagging should be kept in mind in orf-endemic regions.

Animal Identification Systems↗
PubMedDate not supplied

Orf.

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Adult↗
PubMed1990

Human orf. A diagnostic consideration?

We saw four unrelated cases of human orf infection over a 3-month period. Each patient had a clear-cut history of contact with sheep and developed a characteristic painful pustular lesion on the hand. There were no significant systemic symptoms. Examination of an aspirate by electron microscopy confirmed the diagnosis. The lesions resolved spontaneously within 6 weeks. Human orf infection occurs in North America, and although seldom reported, it should be considered in the diagnosis of cutaneous lesions in patients who have exposure to animals associated with it.

Adult↗
PubMed1989

Orf.

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Animals↗
PubMed1988

Human orf in Israel. Report of three cases.

Orf, a viral disease of sheep and goats transmissible to man, is described in three patients living in Israeli cooperative settlements. Characteristically, the disease was manifested as a single, self-limited skin lesion in two of the patients, while in the third patient an unusual coexistence of orf and bullous pemphigoid was found. Not uncommonly, orf may be found in persons working with sheep and goats. Awareness of this disease by physicians may avoid unnecessary testing and treatments.

Adult↗