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Effect of the supine position on uterine and umbilical blood flow during the third trimester of uncomplicated pregnancies in multiparous patients.

We established the effects of the supine position on umbilical blood flow when measured during the third trimester in 30 multiparous, normotensive patients. Blood flow in the umbilical and uterine arteries and blood pressure in the brachial and popliteal arteries were blindly taken by two different observers: first in the lateral and 5 min later in the supine position. There was a significant difference in mean blood pressure between the two postures. However, there was no statistical difference in the pulse pressure or in systolic/diastolic ratio in the umbilical and uterine arteries between the two positions. Postural changes in normotensive multiparous patients do not affect uterine and umbilical blood flow during the third trimester of uncomplicated pregnancies.

Adult↗

Effect of prone and supine positions on functional residual capacity, oxygenation, and respiratory mechanics in ventilated infants and children.

Although numerous reports have described the improvement in PAO2 in patients in the prone position, the underlying mechanism has yet to be determined. Some authors have suggested this phenomenon may be related to an increase in functional residual capacity (FRC); however, no previous studies have described positional changes in FRC in children with severe lung disease or in those under neuromuscular blockade. We measured arterial blood gases, FRC, Rrs, and Crs in supine and prone positions in 30 patients under neuromuscular blockade with lung disorders including moderately severe restrictive (n = 10) and obstructive (n = 10) disease and control subjects without significant lung disease (n = 10). Prone positioning was not associated with a significant increase in FRC in the cohort of 30 patients, nor in any of the subgroups. Although individual patients demonstrated large improvements in oxygenation, a statistically significant (but clinically insignificant) increase in AaPO2 ratio was observed only in the subgroup of patients with obstructive disease (0.35+/-0.03 to 0.38+/-0.04, p = 0.027). There was no correlation between changes in FRC and changes in AaPO2 (r = 0.225, p = 0.23). A significant improvement in Rrs occurred in the prone position compared to supine in patients with obstructive lung disease, decreasing from 0.264+/-0.024 to 0.216+/-0.021 cm H2O/ml/s, p = 0.009. No significant changes in Crs were seen in the prone position. We conclude that prone positioning has no effect on FRC and in this series of 30 patients significantly improved oxygenation only in patients with obstructive airway disease. A significant decrease in Rrs in patients with obstructive lung disease was also observed.

Blood Gas Analysis↗

Flow limitation and dyspnoea in healthy supine subjects during methacholine challenge.

The purpose of this study was to assess whether during standard methacholine (Mch) challenge (concentration up to 128 mg x mL(-1)) healthy supine subjects a) develop tidal expiratory flow limitation (FL) and hyperinflation, and b) whether the onset of tidal FL is associated with dyspnoea. Eight healthy subjects were studied. Dyspnoea was assessed using the Borg scale, FL by the negative expiratory pressure (NEP) method and hyperinflation in terms of decrease in inspiratory capacity (IC). Seven patients became flow limited at Mch doses ranging 4-64 mg x mL(-1), with FL encompassing 34-84% of the control tidal volume. In six of them the onset of tidal FL was associated with little or no dyspnoea and a modest degree of hyperinflation (deltaIC <-0.4 L). In one subject, however, onset of FL was associated with a substantial reduction in IC (0.58 L) and moderately severe dyspnoea. In all of these seven subjects FL was transiently reversed after an IC manoeuvre. In conclusion, the results show that a) most healthy subjects may develop flow limitation and hyperinflation during methacholine challenge in supine position, and b) at onset of flow limitation there is little or no dyspnoea, suggesting that onset of dynamic airway compression per se does not elicit significant dyspnoea. Significant dyspnoea probably only occurs with marked dynamic hyperinflation.

Adult↗

Preoxygenation of pregnant and nonpregnant women in the head-up versus supine position.

The influence of preoxygenation in the supine (n = 10) versus the 45 degrees head-up (n = 10) position on the duration of apnea leading to a decrease in arterial oxygen saturation to 95%, as monitored by pulse oximetry, was investigated in 20 women undergoing elective cesarean section at term of pregnancy. The results were compared with those obtained in a control group of 20 nonpregnant women. In the supine position, the average time to desaturation to 95% was significantly shorter in the pregnant group (173 +/- 4.8 s [mean +/- SD]) than in the control group of nonpregnant women (243 +/- 7.4 s). Using the head-up position resulted in an increase in the desaturation time in the nonpregnant group (331 +/- 7.2 s) but had no significant effect in the pregnant group (156 +/- 2.8 s). We conclude that pregnant women desaturate their arterial blood of oxygen more rapidly than do nonpregnant women. Furthermore, the head-up position extends the duration of apnea that can take place before desaturation occurs in nonpregnant patients.

Adult↗

Milk aspiration in an infant during supine bottle feeding: a case report.

A two-month-old infant died during bottle feeding in the supine position in the caregiver's absence. Scene investigations and autopsy examinations, including alpha-lactalbumin immunohistochemistry of the lungs, revealed the cause of death to be asphyxia due to aspiration of milk pooled in the naso-oral cavity, as a result of unsupervised supine feeding. This case emphasizes the need for an investigation into feeding positions and immunohistochemical examinations for the diagnosis of asphyxia due to milk aspiration.

Animals↗

Role of dangling when moving from supine to standing position.

This article focuses on the cardiovascular adjustments that take place when an individual makes a change in his/her position, particularly when moving from the supine to the standing position (orthostasis). Some individuals may experience a drop in their blood pressure on assuming the standing position, which may lead to dizziness and/or fainting (orthostatic intolerance). Dangling, which is often an intermediary stage of assisting people into the sitting position with their legs hanging over the side of the bed, before moving them into the standing position, is therefore used to ensure that patients are moved safely. This can help to prevent notable reductions in blood pressure. Nurses, therefore, need to be aware of the cardiovascular changes and compensatory mechanisms that take place during orthostasis, in order to be able to make decisions not just about whether their patient can be moved out of bed, but so that it can be done safely without any of the adverse effects of orthostatic intolerance. Those at greatest risk of developing such adverse effects include those with diabetes mellitus, cardiovascular disease and also those with an age-related vagal dysfunction. Some pharmacological agents may also be implicated in contributing to orthostatic intolerance in some individuals. Recommendations for practice include ensuring that dangling the patient is incorporated as part of the procedure of slowly assisting patients out of bed, encouraging leg and foot movement and continually assessing the patient during the procedure. Should any patient show any sign of not tolerating the position change, the procedure should be halted and the patient assisted back into the supine position.

Cardiovascular System↗

Intractable cough associated with the supine body position. Effective therapy with nasal CPAP.

We describe five patients with severe nocturnal cough and daytime somnolence in whom the coughing attacks are triggered by assuming the supine body position. Quantity and quality of the nocturnal cough were evaluated in the sleep laboratory with and without nasal continuous positive airway pressure (N-CPAP). Air flow characteristics were assessed using flow volume and airway resistance loops. Airway anatomy was evaluated bronchoscopically. In all five patients, the cough had a barking quality. Flow-volume loops showed an expiratory collapse phenomenon in two of the patients. Endoscopically, all five patients had signs of airway collapse. All patients had difficulty falling asleep because of coughing and were awakened by it frequently. Sleep times ranged from 2.5 to 4.5 h per night. With N-CPAP pressures ranging from 5 to 13 cm H2O, all five patients had clinically significant improvement in their symptoms. Their sleep times increased to a range of 5 to 7.5 h per night and the daytime somnolence markedly improved or resolved. All five patients requested a N-CPAP unit for home use. We conclude that a cough that is predominantly associated with or exacerbated by the supine body position may be treated effectively with N-CPAP.

Adult↗

The significance of abnormal systolic blood pressure response during supine ergometer exercise and postexercise in ischemic heart disease, studied by exercise radionuclide ventriculography.

The prognostic value of abnormal postexercise systolic blood pressure (BP) response has not been investigated. Therefore, the significance of abnormal BP response during exercise and postexercise was examined in 169 patients with ischemic heart disease subjected to supine ergometer exercise gated equilibrium radionuclide ventriculography, coronary arteriography, and follow up averaging 3.6 years. Abnormal BP response during exercise (exertional "hypotension") was defined as 1) a failure of BP to rise by at least 11 mmHg or 2) an initial rise in BP but subsequent fall by more than 10 mmHg during exercise. Abnormal BP response during postexercise (postexercise "hypertension") was defined as an increase of more than 10 mmHg above the peak exercise BP. Of 169 patients, 51 (30%) had an abnormal BP response. Four types of BP response were identified: exertional "hypotension" (group 1a, n = 11), postexercise "hypertension" (group 1b, n = 30), exertional "hypotension" with postexercise "hypertension" (group 1c, n = 10) and normal BP response (group 2, n = 118). Both average exercise duration and peak heart rate were significantly lower in groups 1a, 1b and 1c than in group 2. The severity of exercise ST-segment depression was greater in groups 1b and 1c than in group 2. However, there was no significant difference in the severity of exercise ST-segment depression between group 1a and group 2. A decline in ejection fraction occurred more frequently in groups 1b and 1c than in group 2. Patients in groups 1a, 1b and 1c had more extensive coronary artery disease (CAD) than did patients in group 2. Medically treated patients with an abnormal BP response (groups 1a, 1b and 1c) had a poorer prognosis than did those with a normal BP response (group 2). These findings suggest that an abnormal BP response during supine exercise is infrequent, but is usually associated with impaired exercise tolerance and severe CAD. An abnormal postexercise BP response is also infrequent, but is more closely associated with evidence of myocardial ischemia and global left ventricular dysfunction than exertional "hypotension". In conclusion, postexercise "hypertension" has the same value as exertional "hypotension" as a predictor of poor prognosis.

Angina Pectoris↗

Does the supine sleeping position have any adverse effects on the child? I. Health in the first six months. The ALSPAC Study Team.

OBJECTIVE: To assess whether the recommendations that infants sleep supine could have adverse health consequences. DESIGN: A prospective study of infants, delivered before, during, and after the Back to Sleep Campaign in the United Kingdom (UK), followed to 6 months of age. The children were part of the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC). Subjects. Singletons born to mothers resident in the three former Bristol-based health districts of Avon in the period June 1991 to December 1992, and for whom questionnaires were completed on sleeping position at 4 to 6 weeks of age (n = 9777); for these infants 8524 questionnaires were also completed at 6 to 8 months of age. MAIN OUTCOME MEASURES: Subjective measures of health, the presence of specific signs and symptoms, duration of sleep at night, and calling the family doctor to the home. RESULTS: Of 43 outcomes considered, after adjustment for 12 factors using logistic regression only 2 were associated with raised risk among infants put to sleep on their back (diaper rash and cradle cap). Infants put to sleep prone had increased risk of a number of health outcomes, including cough and possibly pyrexia. CONCLUSIONS: There is no evidence that putting infants to sleep in the supine position results in increased morbidity, although changes in prevalence of rare disorders would not have been identified.

Adult↗

Does the supine sleeping position have any adverse effects on the child? II. Development in the first 18 months. ALSPAC Study Team.

OBJECTIVE: To assess whether the recommendations that infants sleep supine could have adverse consequences on their motor and mental development. DESIGN: A prospective study of infants, delivered before, during, and after the Back to Sleep Campaign in the United Kingdom, followed to 18 months of age. SUBJECTS: The children were participants of the Avon Longitudinal Study of Pregnancy and Childhood born to mothers resident in the three former Bristol-based health districts of Avon, with expected date of delivery from April 1, 1991 to December 31, 1992. Questionnaires were completed on sleeping position at 4 to 6 weeks of age and sets of standardized questions on development at 6 and 18 months. MAIN OUTCOME MEASURES: Social, communication, fine and gross motor, and total developmental scales based on the Denver Developmental Screening Test at 6 and 18 months. RESULTS: After adjustment for 27 factors using multiple regression, 3 of the 10 scales and subscales significantly distinguished between front and back sleeping position. At 6 months of age, infants put to sleep on their front had a mean score 0.38 SD (95% confidence interval [CI]: 0.28, 0.49) higher on the gross motor scale, 0.11 SD (95% CI: 0.00, 0.23) higher in the social skills scale, and a total development score 0.20 SD (95% CI: 0.10, 0.30) higher than those on their backs. These differences were no longer apparent at 18 months. CONCLUSIONS: There is some evidence that putting infants to sleep in the supine position results in a reduced developmental score at 6 months of age, but this disadvantage appears to be transient. Weighing this against the adverse health effects demonstrated with the prone sleeping position, these results should not change the message of the Back to Sleep Campaign.

Child Development↗

Radiologic diagnosis of traumatic occipitovertebral dissociation: 1. Normal occipitovertebral relationships on lateral radiographs of supine subjects.

OBJECTIVE: The objective of this study was to establish a reliable method of determining the normal occipitovertebral relationship seen on lateral radiographs of the cervical spine in supine subjects in order to recognize alterations of normal that characterize occipitovertebral dissociation. MATERIALS AND METHODS: We define the rostral extension of the posterior cortex of the axis body as the posterior axial line, the distance between the basion (tip of the clivus) and the posterior axial line as the basion-axial interval, and the distance between the basion and the rostral tip of the dens as the basion-dental interval. The basion-axial interval was measured on horizontal-beam lateral radiographs of the cervical spine obtained at a 40-in. (1-m) target-film distance in 400 adults who had no occipitovertebral abnormalities. The basion-dental interval was measured in 374 (94%) of the same cohort of adults in whom the superior cortex of the dens could be identified. All radiographs were obtained with the subjects supine. The excursion of the basion referable to the posterior axial line was determined on lateral flexion and extension radiographs of 25 of the same cohort of adults. The basion-axial interval only was measured on radiographs of 50 children 2-13 years old who had no occipitovertebral abnormalities. RESULTS: In 392 (98%) of the 400 adults, the basion-axial interval did not exceed 12 mm. In eight adults (2%), the basion was situated 1-4 mm posterior to the posterior axial line. The excursion of the basion in flexion and extension ranged from 0 to 10 mm, but did not exceed the 12-mm limit of normal. The basion translated posterior to the posterior axial line in six (24%) of the 25 adults in whom excursion was measured. Of the 400 adults, the basion-dental interval ranged from 2 to 15 mm (mean, 7.5 +/- 4.3 mm [2 SD]); the 95% accuracy range was 11.8 mm. In all 50 children (100%), the basion was within the normal basion-axial interval of 12 mm, and in no instance was the basion posterior to the posterior axial line. CONCLUSION: In adults, the occipitovertebral junction can be considered normal when both the basion-axial interval and basion-dental interval are 12 mm or less. In children less than 13 years old, the basion-dental interval is not reliable because of the variable age at which complete ossification and fusion of the dens occur. The normal basion-axial interval in children did not exceed 12 mm. This simple, anatomically based method of recognizing normal occipitovertebral relationships facilitates identification of occipitovertebral dissociation.

Adult↗

[Reverse Trendelenburg's position vs. supine-horizontal position for induction of general anesthesia in obese neurosurgical patients].

INTRODUCTION: The induction of general endotracheal anesthesia (GETA) is associated with variable period of apnea. Obese patients have reduced oxygen supply during period of apnea. Hypoxemia and subsequent hypercarbia, during period of apnea, are strong stimuli of cerebral blood flow and intracranial pressure increase. OBJECTIVE: The objective of our study was to determine the patient position with safe apnea period (SAP), which will minimize the risk of hypoxemia, as an optimal positioning for induction of GETA in obese neurosurgical patients. METHOD: Obese patients (BMI > 30kg m(-2)) were randomly placed to one of two positions for induction of GETA: group I (n=20) consisted of patients assuming 30 degree reverse Trendelenburg's position; group II (n=20) was in supine-horizontal position. After the arterial oxygen saturation of 100% measured by pulse oximetry (SpO2), patients were allowed to remain apneic. The time required for SpO2 to decline from 100% to 94% was recorded as SAP. The lowest SpO2 after restoration of ventilation and recovery time to 98% SpO2 were also recorded. RESULTS Time needed for SpO2 to decline to 94% was: 196.9 +/- 21.53 sec in group I, and 130.65 +/- 25.73 sec in group II. There was significant difference between groups (I vs. II; p < 0.05). SpO2 of patients in the reverse Trendelenburg's position dropped the least and took the shortest time to restore to 98%. The recovery time was much longer in group II, 132.65 +/- 33.75 (I vs. II; p < 0.05). CONCLUSION: 30 degree reverse Trendelenburg's position provides longer SAP when compared with horizontal-supine positions. This extra time may preclude adverse sequelae resulting from hypoxemia during induction of obese neurosurgical patients.

Anesthesia, General↗

[Evaluation of transmitral flow velocity profile in supine and sitting positions by pulsed Doppler echocardiography in elderly hypertensives].

To evaluate left ventricular diastolic filling properties in elderly hypertensive case with left ventricular hypertrophy (LVH), we investigated the influence of postural change from a supine to sitting position on transmitral flow velocity profile as assessed by pulsed Doppler echocardiography in 12 normotensives (N group) and 24 hypertensives, aged 65 to 80 years. Hypertensive subjects were divided into two groups on the basis of left ventricular mass index (LVMI): 12 hypertensives without LVH (H1 group; LVMI < 130 g/m2); 12 hypertensives with LVH (H2 group; LVMI > 130 g/m2). Peak early filling velocity (E), peak atrial filling velocity (A) and the E/A ratio were similar in the three groups in the supine position. The postural change decreased E and A in N and H1 groups. On the other hand, the change decreased E, but not A in the H2 group. The E/A ratio was decreased in the H2 group compared with both the N and H1 group in the sitting position. As a result, the sitting position increased atrial contribution to diastolic filling in the H2 group. These observations indicate that a reduction in preload changes the transmitral flow velocity profile in elderly hypertensives with left ventricular hypertrophy. The Doppler alterations may be related to impaired left ventricular diastolic function.

Aged↗

[An transcranial Doppler ultrasonography and X-ray study of cervical vertigo patients treated by manipulation in supine position].

OBJECTIVE: To observe the transcranial Doppler ultrasonography and X-ray changes of cervical vertigo patients caused by cervical instability before and after the manipulation treatment in supine position. METHODS: Sixteen cervical vertigo patients who underwent supine manipulation treatment were reviewed retrospectively. After the treatment, the changes of transcranial Doppler ultrasonography of cervical vertebral artery and X-ray of cervical spine were observed. RESULTS: Before the treatment, the mean blood flow velocity of vertebral artery was (48.6+/-3.1) cm/s, much higher than that of the normal group (P<0.05), the means of the horizontal displacement of C3,4 and C4,5 were (3.18+/-0.42) mm and (3.46+/-0.26) mm respectively. After the treatment, the blood flow velocity and the C3,4 horizontal displacement decreased significantly (P<0.05). The effective rate of the manipulation treatment was 100%. CONCLUSION: The manipulation treatment is an effective method for cervical vertigo patients caused by cervical instability, and the effect is correlated with the improvement of the blood flow of cervical artery and the restoration of cervical stability.

Adult↗

Effects of supine body position and low radial accelerations on the visually perceived apparent zenith.

The visually perceived eye level (VPEL) has been shown to shift toward the lower part of the body in upright subjects facing toward the axis of rotation on a centrifuge. This shift occurs in the same direction as the shift in the gravito-inertial forces (Gis) produced by very low radial acceleration (centrifugation) combined with gravity. The purpose of this study was to determine whether the same phenomenon affects the visually perceived apparent zenith (VPAZ) in subjects in a supine position. Twelve supine subjects were instructed to set a luminous target to the VPAZ, either while they were in total darkness and motionless or while undergoing very low centrifugation. Data showed that Gis induced a VPAZ shift similar to that observed for the VPEL. Thus, as is the case for the VPEL, the corresponding logarithmic psychophysical function of the VPAZ may be considered to be a type of oculogravic illusion phenomenon with differences in the subjects' that differs from subject to subject, depending on the subject's sensitivity to low radial accelerations. Data on VPEL and VPAZ support the notion that the subjective perception of eye level in total darkness takes into account changes--even if extremely slight-in the direction of the gravito-inertial forces produced by the combination of gravity and low radial accelerations, although subjects are unaware of the Gi shift. However, depending on the intensity of the radial acceleration and the angular deviation of Gi relative to G, the shift of the VPEL and the VPAZ can be either amplified or attenuated. Moreover, differences between VPEL and VPAZ responses suggest two explanatory assumptions--namely, that this is (1) a peripheral phenomenon dependent on the neurophysiological anisotropy of the otolithic system or (2) a central phenomenon dependent on the relevance assigned to the peripheral information by the integrative sensory functions and the associative processes.

Adult↗

The Ponseti method of treatment for congenital clubfoot: importance of maximal forefoot supination in initial casting.

The correction of cavus deformity requires further supination of the forefoot. In the Ponseti method, the initial cast is applied with the forefoot supinated such that the plane of the metatarsal heads is parallel to the long axis of the tibia. This study reviewed Pirani scores of 27 patients with 38 clubfeet treated over an 18-month period by the Ponseti method to evaluate changes in midfoot deformity after the initial cast. Initial average scores for severity of the lateral border deformity, medial crease, and talonavicular joint reducibility decreased from 0.92, 0.75, and 0.75, respectively, to 0.73, 0.25, and 0.5, respectively, after the first cast. The improvement in Pirani scores provides support for the efficacy of the initial cast to reduce the cavus and also increase the reducibility of the midfoot. Failure to address the cavus deformity with the initial cast as described by Ponseti may lead to persistent rigidity and incomplete correction.

Casts, Surgical↗

Reconstruction of a supinated hypoplastic thumb with combined Huber transfer and derotation osteotomy: a case report.

The use of the abductor digiti minimi transfer to restore opposition in patients with hypoplasia of the thumb has been widely described in the literature. It has been found to be effective in restoring abduction, but less so in restoring the rotational component of opposition. In cases where there is concomitant supination of the thumb, abductor digiti minimi transfer alone would not result in a good pinch as the thumb pulp is rotated away from the opposing finger. We present a case of a 6-year-old girl with a hypoplastic supinated left thumb which resembled a digit. There was also hypoplasia of the index finger. The hand had poor function as a result of lack of opposition of the thumb. The thumb function was restored by combining a derotational osteotomy (80 degrees) with the abductor digiti minimi transfer originally described by Huber. Patient was able to hold small object using key pinch and she could pinch with opposition of the thumb pulp to the middle, ring and little finger pulps when reviewed 2 years post-surgery.

Child↗

[Comparison between the anterior chamber configuration in the supine position and that in the prone position in patients with narrow angle].

PURPOSE: To determine whether the anterior chamber configuration of patients with narrow angle is changed in the prone position. PATIENTS AND METHODS: The study included 16 eyes of 16 patients whose anterior chamber angle was classified as Shaffer 2 or narrower. The prone position test(PPT) and ultrasound biomicroscopy (UBM) were performed on every subject. In the UBM examination, the following parameters were measured both in the supine position and in the prone position: the angle-opening distance at 250 microns from scleral spur(AOD 250), the angle-opening distance at 500 microns from scleral spur(AOD 500), the trabecular-iris angle(TIA), and the anterior chamber depth at the center of the cornea(anterior chamber depth, ACD). RESULTS: While the intraocular pressure was higher after PPT than before the test, every subject was evaluated as negative for PPT. Mean value of every parameter examined was lower in the prone position than in the supine position(AOD 250: 114 microns, vs. 128 microns, AOD 500: 121 microns vs. 144 microns, TIA: 12.1 degrees vs. 15.5 degrees, ACD: 1966 microns vs. 2002 microns), and the change in ACD was statistically significant (p = 0.013). CONCLUSIONS: The anterior chamber configuration of patients with narrow angle is changed in prone position. Such a change can occur in patients classified as negative for PPT.

Aged↗