Congenital heart disease in successive generations; interatrial septal defect in a 63-year woman and her 31-year old son.
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This is the report of an infant seen on June 25, 1960 with preampullary total duodenal obstruction caused by a combined annular pancreas and duodenal stenosis above the ampulla. A gastroduodenostomy was performed. In December 1989, he fathered a 1,700-g boy with preampullary duodenal atresia. A duodeno-duodenostomy was performed successfully by the same pediatric surgeon. Second-generation duodenal obstruction is rare; to our knowledge, there are no other cases.
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No reports to date have described apertognathia as an associated finding of cleidocranial dysostosis. The case of a patient with prognathism and apertognathia associated with cleidocranial dysostosis is reported. Periodontal, restorative, prosthetic, and oral surgical services were necessary to rehabilitate this patient orofacially. A review of the syndrome and of the patient's familial history is presented.
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X-ray mammography is the gold standard for diagnosis of lesions within the female breast. It is also recognized as the technique of choice for breast cancer screening in women over 50-years-old. Notwithstanding these important roles it has shortcomings in terms of limited sensitivity and specificity, especially in younger women. This paper describes the concept of a combined optical density and Doppler ultrasound method proposed initially as a supplement to mammography. A specially devised tissue compressor is also described. Results obtained using test phantoms and initial clinical studies are presented. Neovascularization at the advancing front of neoplastic lesions is believed to underlie detection of lesions by both telediaphanography and Doppler ultrasound.
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The topic of homosexual adjustment problems has never been explored in Taiwan. The aim of this study was to investigate the role of parental bonding in the adjustment problems of homosexuals. A total of 51 young homosexual males, 100 nonhomosexual personnel with adjustment disorder, and 124 controls were administered the Parental Bonding Instrument, the Eysenck Personality Questionnaire, and the Chinese Health Questionnaire. The final parsimonious logistic regression and structural equation modeling showed paternal attachment, especially paternal overprotection, to be a predisposing factor in the development of homosexuality. Paternal attachment, introversion, and neurotic characteristics were key factors in the development of homosexuals. In particular, paternal overprotection played the most important role in the developmental process of male homosexuals. This study can be used as a reference for clinical personnel in caring for male homosexuals.
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PURPOSE: Recent studies have demonstrated a high prevalence of cryptorchidism, decreasing semen quality and increasing incidence of testicular cancer. These changes seem to be interrelated, and may be symptoms of a common underlying entity with foundations in fetal life. We investigated the influence of maternal smoking on fertility status in offspring cryptorchidism. MATERIALS AND METHODS: We prospectively studied consecutive patients presenting to the pediatric surgery department between 1996 and 2005. A total of 157 boys 1 to 5.9 years old underwent surgery for cryptorchidism with simultaneous testicular biopsy, and exhibited well preserved testicular parenchyma. Only white patients with Danish-speaking mothers who had reported pregnancy history including smoking habits during pregnancy and history of the offspring were included. The patients had cryptorchidism only and none received hormonal treatment before surgery. The number of spermatogonia and gonocytes per tubule cross-section was assessed and compared to normal values from autopsy material. RESULTS: The group of boys with cryptorchidism whose mothers had smoked heavily during pregnancy (ie more than 10 cigarettes daily throughout the pregnancy) had a significantly increased risk of bilateral cryptorchidism (52%, or 11 of 21 patients), and a decreased number of spermatogonia and gonocytes per tubule cross-section, which was absolute (0.097 [0 to 0.75]) and age related (14% [0% to 198%] of normal for age) compared to boys whose mothers did not smoke (20%, or 22 of 112 patients, 0.140 [0 to 2.14] and 37% [0% to 563%] of normal for age, p <0.01, p <0.05 and p <0.05, respectively). CONCLUSIONS: A close relationship between maternal smoking during pregnancy and adverse trends in offspring reproductive health in relation to cryptorchidism was observed.
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