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Plasma progesterone concentrations in prairie deermice (Peromyscus maniculatus bairdii) from experimental laboratory populations.

Body weights, ovary weights, plasma progesterone concentrations and ovarian histology were studied in females from asymptotic laboratory populations in which reproduction was inhibited and throughout the oestrous cycle of control nulliparous prairie deermice. Body and ovary weights of population animals were significantly lighter and plasma progesterone concentrations were not significantly different from those of the control females. The control females exhibited cyclic changes in plasma progesterone concentration that were related to the oestrous cycle. The mean plasma progesterone concentration for the nulliparous 'population' females was significantly above the pro-oestrous, and below the metoestrous values of 'control' females, but was not significantly different from values observed at oestrus or dioestrus. The ovaries of 'control' females had significantly larger numbers of follicles and corpora lutea than nulliparous 'population' females but the latter had significantly more atretic follicles.

Animals↗

Serum corticosterone concentrations in reproductively mature and inhibited deermice (Peromyscus maniculatus bairdii).

Serum corticosterone concentrations were measured to see if there was any correlation between adrenal activity and reproductive inhibition. Males and females from two growing and one stable (asymptotic) population had significantly smaller reproductive organs (seminal vesicles, testes, uteri, ovaries) than controls. The weights of the adrenal glands of population mice were smaller, often significantly so, than those of controls, but the mean serum corticosterone concentrations were higher than those of control mice for the two growing populations and significantly higher for the asymptotic population. These data suggest that adrenal function may be associated with the reproductively inhibited condition, but not in a direct or dose-response fashion and that adrenal hyperfunction in this species may not be reflected by adrenal hypertrophy.

Adrenal Glands↗