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PubMed2002

[Parasitology].

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Biomedical Research↗
PubMed1992

[Advances in molecular parasitology].

Recent studies on molecular biology of parasites revealed novel mechanisms for the control of expression of parasitic genes. In trypanosomatid protozoa, unusual characteristics of gene regulation, including polycistronic transcription, trans-RNA splicing and RNA editing have been discovered. This review describes the recent progress of RNA editing in trypanosomes, and trans-splicing in both trypanosomes and nematodes. Studies of the editing of mRNAs in trypanosomatid mitochondria indicate the involvement of small guide RNA molecules, which are encoded in the minicircles and/or maxicircles of kinetoplast DNA. A proposed transesterification model for RNA editing suggests an analogous reaction between RNA editing and RNA splicing. In addition, the development of stable transfection system and success of homologous gene targeting in Trypanosoma and Leishmania are reported.

Animals↗
PubMed2003

[Parasitological risks--from animal husbandry to food and humans].

Livestock management influences the infection risk with parasites. Extensive outdoor management increases the well being of the animals, but may also increase the infection risk with vector or intermediate host transmitted parasites. Several parasites can be transmitted by food. Trichinellosis again represents an increasing threat to human health by newly discovered species, new reservoir hosts and increasing meat import from eastern Europe. Tapeworm infections with Taenia saginata are more frequent than reported in the official statistics. The accurate prevalence and ways of distribution are not known. Toxoplasma gondii is a serious threat to pregnant, non-immune women and their babies. Cat faeces and pork meat are the most important sources of infection. Information, prevention of transmission and diagnostic examination of endangered persons are necessary to minimise the infection risk. Sarcocystis suihominis forms cysts in muscles of pigs, which may cause gastrointestinal symptoms after oral ingestion. In most cases however this protozoan parasite is not or only transiently harmful.

Animal Husbandry↗