Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “OCCLUSIVE DRESSINGS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 613 records · Page 34Linked to original sources
PubMed1994

Cutaneous candidiasis as a cause of delayed surgical wound healing.

BACKGROUND: Reports in the literature of surgical wounds infected with Candida species are scant. OBJECTIVE: We describe a subset of patients with cutaneous candidiasis whose only clinical finding was delayed wound healing. METHODS: Surgical wounds managed with moist occlusive postoperative dressings were observed for delayed healing. RESULTS: Three patients are described who demonstrated delayed wound healing with failure to epithelialize. Fungal cultures from each patient revealed heavy growth of Candida. The problem resolved quickly with a modified wound care regimen and application of an antiyeast cream. CONCLUSION: Cutaneous candidiasis can be a cause of delayed wound healing, especially in surgical wounds treated with antibacterial ointments and occlusive dressings.

Aged↗
PubMed1993

Inhibition of cell proliferation by chronic wound fluid.

It has been proposed that occlusive wound dressings may enhance chronic wound repair by the stimulatory action of the fluid accumulating beneath the dressings. In this report, we investigated the in vitro proliferative effects of chronic wound fluid obtained from under a polyurethane membrane applied for 24 hours to venous ulcers in the ambulatory setting. By measuring cell counts and DNA synthesis, we found that chronic wound fluid inhibited the proliferation of human dermal fibroblasts (p = 0.008) and failed to stimulate the proliferation of microvascular endothelial cells (p = 0.03) and keratinocytes (p = 0.03). The inhibitory activity of chronic wound fluid on fibroblast proliferation was blocked after the fluid was heated to 100 degrees C, but not 56 degrees C, and was mainly restricted to a fraction of chronic wound fluid enriched in components less than 30 kd in molecular weight (p = 0.028). At concentrations ranging from 1% to 4% and in the presence of serum, chronic wound fluid decreased the viability of fibroblasts, as shown by a decreased ability of the cells to exclude trypan blue (p = 0.02), and the viability of endothelial cells, as shown by an increased release of tritiated adenine (p = 0.03). We conclude that the wound fluid obtained from beneath occlusive dressings applied to chronic wounds inhibits cell proliferation.

Journal Article↗
PubMed1997

An overview of the topical management of wounds.

Wounds in animals are a common and frequent reason for seeking veterinary attention. The way in which wounds are managed affect the rate of healing, the time to return to normal function, the final cosmetic appearance, and hence the satisfaction of customers. The management of wounds depends on the stage of wound healing and can include irrigation, mechanical and chemical debridement, the use of antiseptics and antimicrobials, adherent and nonadherent dressings, and miscellaneous topical applications such as aloe vera, honey and live yeast cell derivative. The advantages, disadvantages and indications for initial wound management, topical applicants and dressings are discussed.

Administration, Topical↗
PubMed1989

Viability of skin flaps subjected to simultaneous chemical peel with occlusive taping.

This study was undertaken to determine whether the application of a standardized chemical peel with an occlusive tape dressing to an acutely raised skin flap (as in combining rhytidectomy with chemical peel) affects skin flap viability. Thirty-six 4-cm x 4-cm dorsal skin flaps were raised on guinea pigs and sutured back into place. Eighteen of these flaps were simultaneously treated with a single application of Baker's solution and a 24-hour occlusive tape dressing. A mean of 3.1 cm2 of the nonpeeled flaps necrosed, compared with 6.3 cm2 of the peeled flaps, a statistically significant increase in tissue loss in flaps that were simultaneously chemically peeled. We conclude that application of Baker's solution with an occlusive tape dressing to an acutely raised skin flap impairs skin flap viability and may result in skin flap necrosis.

Animals↗
PubMed2004

Effect of topical nitroglycerine on the survival of ischemic flow-through venous flaps in rabbits.

The purpose of this study was to investigate the effect of transdermal nitroglycerin on the survival of an ischemic one-vein flow-through venous flap (FTVF) model in the rabbit ear. Fifteen New Zealand white male rabbits were randomly divided into three groups: Group 1 (n = 5, 10 flaps)- no dressing on the operative wound; Group 2 (n = 5, 10 flaps)-occlusive film dressing group [polyurethane semipermeable membrane (Op-Site)]; and Group 3 (n = 5, 10 flaps)- transdermal nitroglycerine pad (Novartis-Nitroderm TTS 5 mg) on the wound. Nitroderm TTS and the occlusive film dressing were changed daily postoperatively for 3 days. The percentage of the surviving area and the mean extent of the surviving area to the axial vein were calculated on the postoperative 14 (th) day. Necrotic and surviving areas of flaps were consistent with histopathologic findings. Group 3 (83 percent +/-10.46, 17.4 +/- 3.0 mm) had larger flap surviving areas and longer distances to the axial vein than Group 1 (60 percent +/-15.29, 11.8 +/- 4.3 mm) and Group 2 (58 percent +/-10.25, 12.8 +/- 2.8 mm). The difference was statistically significant ( p < 0.05). This study demonstrated that postoperatively applied transdermal nitroglycerine significantly increased the ischemic FTVF survival area and the survival width to the axial vein.

Administration, Cutaneous↗
PubMed1990

Accelerated epithelization under a highly vapor-permeable wound dressing is associated with increased precipitation of fibrin(ogen) and fibronectin.

In a previous study we showed that the use of a newly developed, highly water vapor permeable, PEU wound dressing accelerates the epithelization of partial-thickness wounds more than an occlusive wound dressing (OpSite) in comparison with air exposure. The purpose of this study was to investigate the distribution of fibrin(ogen), fibronectin, and type IV collagen during the epithelization process under these three conditions. The breathable PEU film enabled coagulation of the wound exudate, preserving it into a semisolid gelatinous state. This coagulum layer contained an abundant amount of fibrin(ogen) and fibronectin. In wounds occluded with OpSite film, depositions of fibrin(ogen) and fibronectin were less extensive. Migrating keratinocytes contained intracellular depositions of fibrin(ogen), suggesting that these cells phagocytize components of the provisional fibrin matrix during wound healing. It was concluded that accelerated epithelization underneath the highly water vapor permeable polyetherurethane film dressing is associated with the presence of a gelatinous coagulum containing fibrin(ogen) and fibronectin. We speculate that the enhanced healing rate might be caused by an increased concentration of growth-promoting factors present in the residual exudate underneath the PEU dressing.

Animals↗