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PubMed1983

[Atopic neurodermatitis after childhood stage; follow-up study of 121 cases].

121 patients suffering from atopic dermatitis (AD) who had been treated in the years 1967 to 1970, being then up to the age of 10, now have been controlled by means of questionnaires. 62 of them were additionally checked by way of personal interrogation and reexamination. The checking comprised of the course of the disease as well as allergies of the respiratory system (AR). The infantile phase of AD began in 55.4 percent of the patients already during the first trimenon, in 88.3 percent in the course of the first year. The average age of manifestation was at 5.5 months. At the time of the control, 58 percent of all patients and 62 percent of the reexamined patients still suffered from AD. Only 7.4 percent were free of cutaneous atopic manifestations after the infantile period. In 31.4 percent of the cases, the diseases cleared up after the infantile phase but reappeared at the age of 5 +/- 2.5 years. 61.2 percent of the patients developed a continuous transition from the infantile to the childhood phase of AD. 54.5 percent of all patients showed the following variations of AR: 33.1 percent suffered from hay fever, 28.1 percent from bronchial asthma, and 11.6 percent from perennial rhinitis. According to statistics, bronchial asthma revealed a prevalence to alternate with AD and occurred at the average age of 4.4 +/- 3.3 years, whereas rhinitis showed itself significantly later. Treatment with hyposensitization on account of AR seldom influenced the course of AD. The prognosis of AD turned out to be worse, if the disease had begun early (within the first or second trimenon), if it occurred with firstborn or single children, or if the patients also had allergies of the respiratory system.

Adolescent↗
PubMed1983

[Comparative results of fluvographic measurements in psoriasis vulgaris and atopic neurodermatitis during climate therapy on the North Sea].

Two groups of patients with psoriasis and atopic dermatitis respectively have been compared with regard to the results of thermal conductivity obtained by fluvographic measures. The abnormal reactions of vessels in both skin diseases initially showed completely opposite fluvographic data. As a result of clinical treatment in the maritime climate of the North Sea, the abnormal reactions of the vessels as well as pathologic skin lesions subsided. These findings are documented by fluvographic data catching up with those found in people without skin problems.

Adult↗
PubMed1983

[Atopic neurodermatitis. Clinical course--pathophysiology--therapy].

Atopic dermatitis is one of the most frequent dermatological diseases. It is a symptom in the framework of the atopic syndrome. Although it is not characteristic for infants and newborns, in respect to localization and form, typical lesions (seropapules, lichenification) and localizations (bends of the arm and knee, face and wrists) may begin at the age of four years and later. Regarding the pathophysiological aspects, non-immunological factors (decrease in the sebaceous gland secretion, reduced barrier function of skin, disturbances in sweat gland secretion) as well as immunological factors (increase in IgE, reduced cell-rendered immunity) play a role. In the focal point of all therapeutic considerations stand efforts to avoid an unnecessarily long and intensive therapy with corticosteroids by replacing corticosteroid treatment by external therapy using other medications (tars, eosin) or by employing UV-A light therapy and by reducing the relapse quota by undertaking measures for bodily hygiene (no soap washing, oil additives in baths, oil and fat creams) and by climate change cures.

Adolescent↗