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[Role of medical technologists in the infection control team].

The infection control team (ICT) plays important roles in many different aspects of infection control. They include (1) surveillance for hospital-acquired infection, (2) developing the infection control manual, (3) checking that the manual is followed correctly, (4) giving information about the isolation of microorganisms in the hospital, (5) educating and instructing medical staff, etc. Many data have been accumulated on a database in the microbiology laboratory. Bacterial samples are also examined in the microbiological laboratory therefore medical technologists will be the first to notice hospital-acquired infection. Offering prompt information, obtained by surveillance or routine work, greatly contributes to infection control. Furthermore, a 24hr system for the microbiological laboratory may prevent occupational infection of health care workers. The role of the medical technologist in ICT is thus important. To prevent outbreaks of infection, the regional network is also important for the collection of information about the pathogen and the susceptibility of antimicrobial agents in the region. The medical technologist should participate in and communicate with this network. As mentioned above, the inclusion of medical technologists in infection control practice is essential. To participate in the ICT, medical technologists need to have communication skills, and be recognized by other team members as an essential member.

Bacteria↗

[The Italian contribution to the application of high-technology methods to clinical trials].

Clinical trials are important research tools currently used in assessing new drugs and therapeutic strategies, which are unable to produce large effects evaluable in small series of patients. We describe methodological principles of clinical trials and significant advantages in their implementation produced by using a computer network for long-distance modem transmission of echocardiographic images and clinical data. This network has been recently developed in Italy and is operative at the University of Bari and the Associazione per la Ricerca in Cardiologia. Several clinical participating centers of the CEDIM Study and PHASE Study are connected in real time to a data center via modem by a special telephone network (RFD) of the Italian State Telephone Company (SIP). We describe the configuration, main features and applicative potential of such a powerful research tool in modem clinical trial methodology.

Cardiology↗

[Computerization of medical technology].

The object of computerization is practical medical technology which is regarded as a complex of methodological and instrumental support for maintaining a physician-patient dialogue. The methodological support remain to be a prerogative of medicine and, consequently, relatively conservative. The instrumental support (as an aid for the methodological one) permits a constant extension of its stores. That is why the present paper considers the computerization of medical technologies in the context of extension of instrumental support. The replacement of paper technology in medicine by computerized one should primarily increase the level and quality of obtaining information on the patient and create high-levelled computerized systems: diagnostic monitoring, reference, expert ones. The creation of automatic working places for specialists of therapeutical-and-prophylactic institutions (TPI), their incorporation into the local computer systems of functional departments form an instrumental basis for informatization of the whole TPI. A scheme of the computer system of a resuscitation and intensive care is given as an example.

Computer Communication Networks↗

Barriers to rural physician use of a digital health sciences library.

BACKGROUND: Rural physicians need access to quality medical information, but accessing information is difficult in rural settings. Digital health sciences libraries (DHSLs) offer the potential to make information more accessible to rural physicians. A telemedicine network was deployed to six rural hospitals in Iowa. Computers were installed allowing access to a DHSL and training sessions were held. The purpose of this study was to examine the barriers to use of a DHSL by rural physicians. METHODS: Approximately one year after deployment of the telemedicine network, physicians were surveyed using a modified critical incident technique. RESULTS: Seventy percent of the eligible physicians responded and 33% had used the DHSL. Primary barriers included insufficient training, being too time consuming to use, and distance of computers from physicians' practice sites. Non-DHSL users cited the difficulty of using the DHSL as their greatest barrier, while DHSL users cited the quality of the information resources. CONCLUSIONS: This study identifies a number of barriers that exist to rural physicians use of a DHSL. Potential solutions to these barriers are discussed. DHSLs will finally reach their potential when they can be delivered by easy to use handheld computers seamlessly integrated into the rural physician's workflow.

Adult↗

Strategies and measures for our next century.

The centennial of the Medical Library Association offers an opportunity to reflect with some satisfaction on accomplishments and to consider the future. The Western Governors University is an illustration of the dynamic future. Professional values constitute both distinguishing characteristics and steadfast guides for succeeding in this complex environment. Powerful collaborative technologies now make it possible to overcome challenges that are beyond the capabilities of an individual librarian or library. Providing organized access to the Internet exemplifies these challenges. The profession has a strong history of cooperation but to take full advantage of collaboration, institutional and cultural barriers must be overcome. The National Network of Libraries of Medicine (NN/LM) should be the facilitating agent in this process.

Community Networks↗

[Men of science in Brazil: colonial empires and the circulation of information (1780-1810)].

In the eighteenth century, the Portuguese imperial model yielded to other international strategies, organized according to a logic of networks that revolved around centers for the production of knowledge and the creation and redistribution of scientific products. Within this context, Portugal underwent a 'conversion' that drew it towards the French and British colonial systems. A self-legitimized scientific field was one of the corollaries of the European Enlightenment, a process that involved at least two generations of men of science and, most importantly, whose success relied on the engagement of the State. This process did not transpire systemactically in Brazil, although many of the country's men of science were well abreast of the Enlightenment's most modern philosophical and scientific theories. Policies to foster scientific activities in Brazil did not occur in tandem with broad, deep transformations in the spheres of administration, sociability, institutions, economics, or culture.

Brazil↗

A method to convert HDTV videos of broadcast satellite to RealSystem multimedia contents.

Recently, the Internet is widely used in the field of medicine. Daily use of e-mail for medical communication is very common. Also various information regarding hospitals can be accessed via the network. Apart from this practical use of the computer network, the mediums of telemedicine, tele-education, and telecare are also available. The Medical Information Network via Communications Satellite for University Hospital (MINCS-UH; http://www.umin.ac.jp/mincs/) was constructed by the Ministry of Education, Culture, Sports, Science and Technology. These programs feature high quality images viewed on High Definition Television (HDTV) through the Broadcast Satellite (BS). We have compiled a video library of MINCS-UH program contents with W-VHS tapes for HDTV and VHS or S-VHS tapesfor NTSC, available to medical staff in our university hospital through the Hospital local area network (Hospital intranet). We have also constructed a web-based streaming system that is a low cost, user-friendly multimedia delivery system capable of providing medical lectures. This system was constructed using the RealSystem package with the Internet Protocol (IP) network. Although the image quality of RealSystem is inferior to that of the original video, users can review lectures and medical congress presentations with video and audio through Hospital intranet, at any time that is convenient to them. This system can also be an efficient tool for distance learning and supports the diffusion of up-to-date information and technology to busy physicians via the Internet.

Education, Distance↗

Selling the silver: country house libraries and the history of science.

Country houses have long acted as scholarly research centres, and the contents and organization of their libraries reveal how knowledge was created and transmitted through scientific networks: they provide material evidence of intellectual and social cultures. Manuscripts are particularly appreciated in this regard because they are unique, but individual books also differ and copies of the same book are not always identical -- they might be annotated by authors and readers, and the printed text can vary as well -- so they also carry invaluable historical information. When libraries are broken up, access to the past is permanently blocked.

Biological Science Disciplines↗

Application of knowledge information processing methods to biochemical engineering, biomedical and bioinformatics fields.

In biochemical and biomedical engineering fields there are a variety of phenomena with many complex chemical reactions, in which many genes and proteins affect transcription or enzyme activity of others. It is difficult to analyze and estimate many of these phenomena using conventional mathematical models. Recently some knowledge information processing methods, such as the artificial neural network (ANN), fuzzy reasoning, fuzzy neural network (FNN), fuzzy adaptive resonance theory (fuzzy ART) and the genetics algorithm (GA), were developed in the computer science field and have been applied to analysis in a variety of research fields. In this chapter, these methods will be briefly reviewed. Next, the application of these methods in the biochemical field will be introduced, instancing two examples in actual industrial processes. In addition, the application in the biomedical and bioinformatics field as another attractive field will be reviewed. Two examples are our research such as the prediction of prognosis for cancer patients from DNA microarray data using FNN and gene clustering for DNA microarray data using fuzzy ART.

Artificial Intelligence↗

Predicting protein structural class with pseudo-amino acid composition and support vector machine fusion network.

Because a priori knowledge of a protein structural class can provide useful information about its overall structure, the determination of protein structural class is a quite meaningful topic in protein science. However, with the rapid increase in newly found protein sequences entering into databanks, it is both time-consuming and expensive to do so based solely on experimental techniques. Therefore, it is vitally important to develop a computational method for predicting the protein structural class quickly and accurately. To deal with the challenge, this article presents a dual-layer support vector machine (SVM) fusion network that is featured by using a different pseudo-amino acid composition (PseAA). The PseAA here contains much information that is related to the sequence order of a protein and the distribution of the hydrophobic amino acids along its chain. As a showcase, the rigorous jackknife cross-validation test was performed on the two benchmark data sets constructed by Zhou. A significant enhancement in success rates was observed, indicating that the current approach may serve as a powerful complementary tool to other existing methods in this area.

Algorithms↗

High-speed memory scanning: a behavioral argument for a serial oscillatory model.

In order to account for the memory span [G.A. Miller, The magical number seven, plus minus two: some limits on our capacity for processing information, Psychol. Rev. 63 (1956) 81-97.], the magical number seven, plus minus two, and high-speed scanning in human memory ¿S. Sternberg, High speed scanning in human memory, Science 153 (1966) 652-654., Lisman and collaborators [O. Jensen, J.E. Lisman, An oscillatory short-term memory buffer model can account for data on the Sternberg task, J. Neurosci. 18 (1998) 10688-10699; J.E. Lisman, M.A.P. Idiart, Storage of 7+/-2 short-term memories in oscillatory subcycles, Science 267 (1995), 1512-1515.] proposed an oscillatory short-term memory buffer model. In this neurophysiological model: "a single brain network can separately maintain up to seven memories by a multiplexing mechanism that uses theta and gamma brain oscillations for clocking. A memory is represented by groups of neurons that fire in the same gamma cycle" ¿O. Jensen, J.E. Lisman, An oscillatory short-term memory buffer model can account for data on the Sternberg task, J. Neurosci. 18 (1998) 10688-10699, p. 10688. To test this model, we tried to modify the memory scanning time by shifting the gamma oscillation frequency. To this aim, we replicated the visual short-term memory scanning task ¿S. Sternberg, High speed scanning in human memory, Science 153 (1966) 652-654., and we simultaneously used the protocol that Treisman ¿M. Treisman, A. Faulkner, P.L.N. Naish, D. Brogan, The internal clock: evidence for a temporal oscillator underlying time perception with some estimates of its characteristics frequency, Perception 19 (1990) 705-743. designed to drive, slowing down or speeding up, a temporal oscillator acting in the gamma range ¿J.G.R. Jefferys, R.D. Traub, M.A. Whittington, Neuronal networks for induced "40 Hz rhythms, Trends Neurosci. 19 (1996) 202-208; W. MacKay, Synchronized neuronal oscillations and their role in motor processes, Trends Cog. Sci. 1 (1997) 176-183; M. Treisman, N. Cook, P.L.N. Naish, J.K. MacCrone, The internal clock: electroencephalographic evidence for oscillatory processes underlying time perception, Q. J. Exp. Psychol. 47A (1994) 241-289.. In this protocol, an auditory periodic stimulus (click train) was delivered at various frequencies during the task. The reaction time (RT), the slope, and the intercept of the linear function associating RT to memorized list length showed systematic modulations according to the stimulation frequency. The predicted driving effects due to the click trains were obtained, consisting of localised modulations of performance on the stimulation frequency band. We argue that memory scanning is indeed paced by a temporal oscillator, thus providing behavioral arguments for the serial oscillatory model of Lisman.

Adult↗

The Missouri planning grant for the education and training of health sciences librarians.

The planning grant at the School of Library and Informational Science (SLIS) at the University of Missouri has two aims: (a) developing a model curriculum for health sciences librarianship at the master's level and (b) developing materials that can be delivered by alternative instructional methods. To accomplish the first aim, the faculty will investigate the possibility of offering courses in other disciplines, such as health care administration, educational technology, adult education, and medical sociology. In addition, the SLIS faculty will investigate the development of new kinds of placement for the students' practicum experience. To reach the second aim, the SLIS faculty will investigate alternative means of delivering both graduate and continuing education. Three instructional modalities will be evaluated. Some material will be delivered via satellite broadcast, some material will be made available via the World Wide Web and some will be presented in an intensive seminar. The outcome of the planning grant will be two distinct plans. The first will be a plan for the curriculum in health sciences librarianship at the master's level. The second will be a plan for offering instruction through alternative methods, both for graduate education and for continuing education.

Computer Communication Networks↗

Exploring the alcohol expectancy memory network: the utility of free associates.

Alcohol expectancies are theorized to operate through associative memory networks. These networks are thought to differ on the basis of individual experience (direct and vicarious) with alcohol. Free-associate probabilities have been used in cognitive psychology as a metric of the associative strength of words to other words; this method has been used to establish the relationships within a semantic memory network. Participants from a large college sample were asked to free associate to the phrase "Alcohol makes me ______" They were also asked about their quantity of alcohol consumption. Results showed that specific responses were given with different probabilities by individuals who drank at different levels. The heaviest drinkers tended to have more positive and arousing responses than did lighter drinkers, who tended to have more negative and sedating responses. These results underscore the need to take into account relevant individual differences in behavior and experience when characterizing semantic networks.

Adolescent↗