Winter mortality in elderly people in Britain: lack of social gradient in winter excess mortality is obvious in Denmark.
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alpha 1-Antitrypsin phenotypes were determined in 1,395 male Saskatchewan grain buyers. These included 1,254 type M, 80 MS, 35 MZ and 26 which were untyped or other rare phenotypes. Sibling and offspring of the MS men had a significantly greater number of deaths (p less than 0.01). Offspring of MZ men also had an increased number of deaths. These appeared to occur in all age except in those 2-17 years of age. This finding raises questions about the role of both the S and Z alleles.
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