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PubMed2006

Removal of nonthyroidal neck masses with improved cosmetic outcomes in skin-lifting surgery.

OBJECTIVE: To evaluate the cosmetic benefit of neck skin-lifting surgery for the removal of nonthyroidal neck masses. STUDY DESIGN AND SETTING: Fifty patients with neck masses were divided into the following 2 surgical groups that were matched in age, sex, and the size, location, and pathology of lesions: skin lifting (n = 25) and conventional (n = 25). The operation time, hospital stay, complications, and subjective satisfaction with the incision scar as assessed on a visual analogue scale (VAS) were compared between the 2 groups. RESULTS: All but 2 lesions (lymphomas) were benign and were removed completely, drained, or biopsied. The surgery time, hospital stay, and complication rates did not differ significantly between the groups. The mean satisfaction score of the patients was 8.2 +/- 1.1 in the skin-lifting surgery group and 4.8 +/- 2.5 in the controls (P < 0.001). The incision scars were commonly hidden by natural hair or collars in the patients who received skin-lifting surgery. CONCLUSION: This surgical technique can be safely applied to most benign masses in the entire neck excluding the thyroid region, especially in patients who prefer neck scars to be invisible. EBM RATING: B-2b.

Abscess↗
PubMed2003

Colony lift assay using cell-coated filters: a fast and efficient method to screen phage libraries for cell-binding clones.

For efficient screening of phage antibody libraries obtained by selection on whole cells, we have developed a modified colony lift assay using cell-coated filters. Both cells growing in suspension as well as adherent cells can be coated onto nitrocellulose filters and used to detect bacterial colonies responsible for the production of cell-binding (specific) single chain variable fragment (scFv) antibodies. We demonstrate, using a selected library developed in our laboratory (named "AB" library) as a model system, that the frequency of specific clones as detected by colony lift assay using cell-coated filter is comparable to the frequency of positive clones as detected by the "classical" method (i.e. random picking and flow cytometric analysis). However, the colony lift assay enables detection and isolation of a higher number of specific clones as compared to the random pick. This is due to screening of a much higher number of clones simultaneously (it is possible to screen at least 1000 clones plated on one 9-cm agar dish). Using this method, clones occurring at a low frequency (such as present in early selection rounds) can be detected and isolated efficiently. We clearly demonstrate the usefulness of the colony lift assay with cell-coated filter by applying it to screen the head-and-neck carcinoma (HN) library (a selected library generated in our laboratory). Using the assay, but not the random picking, we were able to isolate specific clones from 2nd to 3rd selection rounds of the HN library.

Animals↗
PubMed1998

A new technique applicable to pediatric laparoscopic surgery: abdominal wall 'area lifting' with subcutaneous wiring.

BACKGROUND: Recently, the authors developed a unique method of laparoscopic surgery without pneumoperitoneum: "area lifting of the abdominal wall with subcutaneous wiring." METHODS: In this gasless procedure, the anterior abdominal wall is pulled upward by a pair of wires placed subcutaneously and held by thick sutures for "hanger lifting." Simultaneous lifting of a pair of subcutaneous wires across the abdomen, produces a wide, roof-shaped intraabdominal space sufficient for laparoscopic surgical procedures. The practical aspects of this gasless technique, as well as the authors' limited experience with this method in 24 children, ranging from 8 days to 15 years of age is presented. These children have had various pathologies including splenomegaly, rectal prolapse, ovarian cyst, gall stone, adrenal neuroblastoma, and abdominal wall abscess. CONCLUSIONS: Gasless laparoscopic surgery with double subcutaneous wiring is safe for children including neonates and those with respiratory compromise because all operative procedures are performed under normal abdominal pressure. Because of the highly elastic abdominal wall musculature inherent in children, this selective area lifting of abdominal wall creates a relatively larger peritoneal volume than in adults.

Abdominal Muscles↗
PubMed1998

Coordination between the lumbar spine lordosis and trunk angle during weight lifting.

OBJECTIVE: To analyze the coordination of the lumbo-sacral angle (lumbar spine lordosis) and the trunk inclination during lifting of different loads. STUDY DESIGN: Kinematic data of spine motion were analyzed. The parameters characterizing the relationships between the lordosis and the trunk inclination angle were estimated. BACKGROUND: The shape of the spine has been analyzed mostly for static or quasi-static conditions. The parameters relating the lumbar spine lordosis and trunk inclination in dynamics have not been analyzed. METHODS: Healthy subjects performed unconstrained weight lifts from ground to mid-thigh level. Kinematic data were derived from the tracking of markers (light-emitted diodes) placed over the spine and pelvis using an OPTPTRAK system. The relationship between lordosis and trunk inclination was analyzed. RESULTS: The relationship between lumbar spine curvature (lumbo-sacral angle or lordosis) and trunk inclination during weight lifting was described by an exponential function with three parameters. These were the lordosis extremes associated with the horizontal and vertical positions of the trunk and the trunk inclination when lordosis equals zero. The absolute value of the lordosis angle decreases at the onset of the extension phase of lifting when the load increases, implying active reaction of musculosceletal system to increasing load. CONCLUSIONS: The changes in the lordosis and trunk inclination are strictly correlated implying that the nervous system actively coordinates the degrees of freedom of the spine, providing an inter-joint synergy.

Journal Article↗
PubMedDate not supplied

The belly-press test for the physical examination of the subscapularis muscle: electromyographic validation and comparison to the lift-off test.

The purpose of this study was to determine the validity of the belly-press test as a clinical test for the subscapularis muscle with the use of electromyography (EMG). In addition, the belly-press and lift-off tests were compared to determine whether the two physical examination techniques are equivalent in their evaluation of the upper and lower portions of the subscapularis muscle. EMG data of 7 muscles (upper subscapularis, lower subscapularis, infraspinatus, latissimus dorsi, teres major, pectoralis major, and supraspinatus) were studied in 16 healthy volunteers. Average EMG amplitudes were contrasted within and between tests. Both the belly-press and lift-off tests activated the upper and lower portions of the subscapularis muscle greater than all other muscles, indicating that both tests are valid and specific for evaluation of the subscapularis muscle (P <.05). The belly-press test was found to activate the upper subscapularis muscle significantly more than the lift-off test (P <.05), whereas the lift-off test was found to pose a significantly greater challenge to the lower subscapularis muscle than the belly-press test (P <.05). These findings may improve the clinical testing and assessment of the subscapularis muscle.

Adult↗
PubMedDate not supplied

Efficient production of L-(+)-lactic acid using mycelial cotton-like flocs of Rhizopus oryzae in an air-lift bioreactor.

L-(+)-Lactic acid production was enhanced in a culture of Rhizopus oryzae by induction of a mycelial flocs morphology. By conventional culture the morphology of R. oryzae is that of a pellet-like cake; however, when mineral support and poly(ethylene oxide) are added to the culture, the morphology of R. oryzae takes on a cotton-like appearance. The formation of these cotton-like mycelial flocs was induced by the addition of 5 ppm poly(ethylene oxide) into a 12-14 h culture containing 3 g/L of the mineral support before the formation of the conventional pellet morphology. The cotton-like flocs were also formed in cultures grown in an air-lift bioreactor. This morphology allowed effective mass transfer inside the flocs and effective fluidity of culture broth in an air-lift bioreactor. L-(+)-Lactic acid concentration produced by mycelial flocs in an air-lift bioreactor, with the support and poly(ethylene oxide), was 104.6 g/L with a yield of 0.87 using 120 g/L of glucose as the substrate; for this culture without both, the concentration was 43.2 g/L. These results demonstrate that cotton-like mycelial flocs are the optimal morphology for use in the air-lift bioreactor culture of R. oryzae.

Bioreactors↗
PubMed2003

Effects of sinus lifting on voice quality. A prospective study and risk assessment.

A variety of potential complications associated with sinus lift surgery have been reported in the literature. However, potential alterations of voice quality following sinus elevation have so far not been mentioned or evaluated scientifically. For the majority of patients, slight changes of the voice pattern are of no importance. However, for voice professionals, whose voices have become part of their distinctive profession or trademark, minimal changes may have dramatic consequences. This specific group of patients, such as speakers, actors and singers, depend on the particular quality and timbre of their voice for their livelihood. Consequently, the purpose of this study was to assess the effects of sinus lifting on voice quality in the above patient group. In a collaborative interdisciplinary effort, the Departments of Oral Surgery and Otorhinolaryngology, Section of Phoniatrics and Logopedics, thoroughly evaluated a series of voice parameters of four patients undergoing sinus lifting pre- and postoperatively. The parameters analyzed included pitch, dynamic range, sound pressure level, percent jitter, percent shimmer and noise-to-harmonics ratio with special emphasis on formant analysis. No changes were detected in any of the commonly evaluated parameters. These were rated subjectively by patients and their friends or relatives and objectively with instrumental tools under isolated phoniatric lab conditions. In conclusion, sinus lift surgery appears to be a safe, predictable evidence-based method for regenerating the highly atrophic posterior maxilla, which does not jeopardize the individual characteristic voice pattern of high-profile patients critically dependent on their voices for their livelihood.

Adult↗
PubMed2002

Changes in hemodynamics and autonomic nervous activity in patients undergoing laparoscopic cholecystectomy: differences between the pneumoperitoneum and abdominal wall-lifting method.

BACKGROUND AND STUDY AIMS: Intraoperative changes in circulatory hemodynamics and autonomic nervous activity were evaluated in 33 patients with cholelithiasis who underwent laparoscopic cholecystectomy. PATIENTS AND METHODS: Of these patients, 18 were treated using a pneumoperitoneum (group G) and 15 using the abdominal wall-lifting method (group WL). Their ECG, blood pressure, arterial oxygen saturation, and expiratory carbon dioxide partial pressure were monitored. Autonomic nervous function was evaluated by spectral analysis of the heart rate. RESULTS: Mean blood pressure increased significantly in group G during surgery, but did not vary in group WL during any stage of surgery. The high-frequency (HF) power, an index of parasympathetic activity, decreased significantly in group G after pneumoperitoneum. However, the HF power did not decrease significantly in group WL. The LF/HF ratio, an index of sympathetic activity, increased significantly in group G after pneumoperitoneum, but did not vary in group WL. In addition, the incidence of ventricular or supraventricular arrhythmias and the severity of the arrhythmias as determined by Lown's classification were higher in group G than in group WL. These findings suggest that intraoperative changes in autonomic nervous activity, due to increased intra-abdominal pressure, were smaller in patients undergoing laparoscopic cholecystectomy using the abdominal wall-lifting method than in those undergoing laparoscopic cholecystectomy using pneumoperitoneum. The results also demonstrated that hemodynamic changes were smaller in patients undergoing the abdominal wall-lifting method than in those undergoing pneumoperitoneum. CONCLUSIONS: It was concluded that hemodynamics should be carefully monitored during pneumoperitoneum, and that the abdominal wall-lifting approach in laparoscopic cholecystectomy is a method worthy of consideration for elderly patients or those with cardiopulmonary complications.

Abdominal Muscles↗
PubMed1990

The effect of an abdominal belt on trunk muscle activity and intra-abdominal pressure during squat lifts.

The purpose of this study was to determine whether abdominal belts such as those prescribed to industrial workers reduced trunk muscle activity and/or increased intra-abdominal pressure (IAP). In this study, six subjects lifted loads (72.7 to 90.9 kg) both with and without wearing a weightlifter belt. In addition, further trial conditions required that subjects lifted both with the breath held or continuously expiring on lifting effort. Dynamic hand loads were recorded together with intra-abdominal pressure (IAP) and abdominal, intercostal and low back EMG. Every subject demonstrated an increase in IAP when wearing the belt during both breathing conditions: 99 mmHg with no belt; 120 mmHg wearing belt (p less than 0.0001). However, it was also found that significant increases in IAP occurred (p less than 0.017) when the breath was held versus exhaling with or without the belt. One would expect that if the belt relieved either the direct compressive load on the spine or assisted IAP to produce an extensor moment then this would be reflected in diminished extensor muscle activity. Erector spinae activity tended to be lower with the breath held suggesting a reduced load on the lumbar spine although wearing a belt did not augment this reduction. In the case studies with subjects wearing an ergogenic corset designed for use by industrial manual materials handlers, perceptions of improved trunk stability were reported. However, the muscle activity and IAP results of this study during short duration lifting tasks make it difficult to justify the prescription of abdominal belts to workers.

Abdominal Muscles↗
PubMed1991

Inertial effects from single body segments in dynamic analysis of lifting.

Biomechanical calculations of loads on the locomotor system in lifting tasks are often based on static models. Several investigators have shown, though, that in a dynamic act like lifting, inertial effects are not generally negligible. A complete dynamic analysis includes the calculation of linear and angular accelerations of body segments and is rather complicated to carry out. So it was of interest to find out whether the contribution of single body segments to the dynamic effects of the whole body might be negligible. Ten male subjects lifted a 12.8 kg box using two different techniques and two speeds. Ground reactions and body segment movements were recorded and reaction forces and net moments at different joints were calculated with static, dynamic and 'semidynamic' methods. The latter method incorporated the ground reaction forces as measured from a force plate but was otherwise equal to the static method. The results from semidynamic analyses agreed well with those from complete dynamic analyses for the ankle, knee, hip, and L5/S1 joints. For example, the semidynamically calculated peak moments at L5/S1 differed on average less than 3% from the dynamically calculated values. The contributions of the lower extremities and the pelvis to the dynamic effects of the whole body seemed to be quite small. The less complicated semidynamic method offers a good alternative to a fully dynamic analysis for estimations of peak moments in the lower back, at least for the studied lifting techniques.

Adult↗
PubMedDate not supplied

Biomechanically and electromyographically assessed load on the spine in self-paced and force-paced lifting work.

The purpose of this study was to measure dose of spinal load when different pacing methods were applied to lifting work and to develop methodology for such measurements. The compressive load on the spine computed by a dynamic biomechanical model and the electromyographic activity of back muscles were used for describing the spinal load. Five men and five women worked in a laboratory on two days lifting a box up and down for 30 min on both days, on one day force-paced (4 lifts/min), and on the other self-paced in random order. The weight of the box was rated by the subjects to be acceptable for the work done. The lift rate of our female subjects was higher and that of the male subjects lower in self-paced than in force-paced work. There were no significant differences in peak lumbosacral compressions nor in the amplitude distributions of electromyography between the two pacing methods. The biomechanically-calculated compressive forces on the spine were lower (about 2.7 kN for the men and 2.3 kN for women) than the biomechanical recommendations for safe lifting, but the EMG activity showed quite high peaks so that for 1% of work time the activity was on women above 60% and on men above 40% of the activity during maximum isometric voluntary test contraction.

Adult↗
PubMed2001

Experimental determination of baseball spin and lift.

The aim of this study was to develop a new method for the determination of lift on spinning baseballs. Inertial trajectories of (a) ball surface markers during the first metre of flight and (b) the centre of mass trajectory near home-plate were measured in a pitch using high-speed video. A theoretical model was developed, incorporating aerodynamic Magnus-Robins lift, drag and cross forces, which predicts the centre of mass and marker trajectories. Parameters including initial conditions and aerodynamic coefficients were estimated iteratively by minimizing the error between predicted and measured trajectories. We compare the resulting lift coefficients and spin parameter values with those of previous studies. Lift on four-seam pitches can be as much as three times that of two-seam pitches, although this disparity is reduced for spin parameters greater than 0.4.

Baseball↗
PubMed1990

Heavy lifting during pregnancy--a hazard to the fetus? A prospective study.

The influence of heavy lifting during pregnancy on gestational age, birthweight and the risk of fetal death (spontaneous abortion or stillbirth) was investigated in a prospective study of 3906 occupationally active women. Information on exposure was collected at the women's first contact with the antenatal care centres in Orebro County from October 1980 to June 1983. Logistic and linear regression were used to analyse the data, allowing for several non-occupational factors in the models. Women who reported heavy lifting did not have in general more unfavourable outcomes than other women, although the risk estimates varied between different occupational categories. Lifting of weights greater than or equal to 12 kg more than 50 times per week increased the risk of pre-term birth (less than 37 weeks of gestation--odds ratio 1.7), but only among women who stopped working before the 32nd week of pregnancy. Unfavourable outcomes were more common among those who reported chemical exposure during pregnancy. The preventive routines and regulations in Sweden may have helped to reduce possible risks from heavy lifting during pregnancy.

Abortion, Spontaneous↗
PubMed1994

Heavy lifting at work and risk of genital prolapse and herniated lumbar disc in assistant nurses.

Lifting of heavy burdens increases the intra-abdominal pressure, and may induce an increased risk of prolapse of the female internal genitals. While taking care of patients, the nursing staff in hospitals and nursing homes are exposed to heavy lifting. Scientifically uncontrolled causal observations among assistant nurses gave rise to the assumption of an increased risk. To test this hypothesis, a register study was carried out to investigate the risk of genital prolapse among assistant nurses compared with the female Danish population in general. For validation, the incidence of operation due to herniated lumbar disc was investigated. Two registers were used for the analyses, a pension fund register and the Danish National Registry of Hospitalized Patients. Some 28,619 assistant nurses, aged 20-69 years, and 1,652,533 controls of similar age were included. Operations due to genital prolapse and herniated lumbar disc were recorded during one year. The odds ratio (OR) with 95 per cent confidence intervals for the risk of operation due to genital prolapse was significantly increased among assistant nurses, OR = 1.6 (1.3-1.9), P < 0.0001. Correspondingly, the risk of operation for herniated lumbar disc was significantly increased for assistant nurses, OR = 1.6 (1.2-2.2), P < 0.01. We conclude that operations due to genital prolapse are more common among assistant nurses than among the overall female population. Based on this finding, we hypothesize that heavy lifting at work may be the underlying cause. This study confirmed the suggestion of previous epidemiological studies that herniated lumbar disc is associated with heavy lifting at work.

Adult↗
PubMed1988

Effects of soft tissue mobilization (Rolfing pelvic lift) on parasympathetic tone in two age groups.

The effects of a soft tissue mobilization procedure, the Rolfing pelvic lift, on parasympathetic tone was studied in healthy adult men. Parasympathetic tone was assessed 1) by quantifying the amplitude of the respiratory sinus arrhythmia from the heart rate pattern and 2) by measuring heart rate. Heart rate patterns were assessed during the pelvic lift and during the durational touch and baseline control conditions. Two groups of healthy subjects were tested: Group 1 contained 20 subjects aged 26 to 41 years, and Group 2 contained 10 subjects aged 55 to 68 years. In Group 1, the pelvic lift elicited a somatovisceral-parasympathetic reflex characterized by a significant increase in parasympathetic tone relative to durational touch and baseline conditions. Group 2 did not exhibit a parasympathetic change during the pelvic lift. The results of this study contribute to our understanding of pelvic mobilization techniques and may help to explain why these techniques have been clinically successful in treating myofascial pain syndromes and other musculoskeletal dysfunctions characterized by reduced parasympathetic tone and excessive sympathetic activity.

Adult↗
PubMed1991

Slash pine bud dormancy as affected by lifting date and root wrenching in the nursery.

Bud dormancy of root wrenched and unwrenched slash pine (Pinus elliottii Engelm.) seedlings growing in a forest nursery was measured on five lifting dates. Determination of bud dormancy was based on days to budbreak (DBB) under optimal growing conditions, mitotic activity in the apical meristem, chilling hours accumulated, and bud morphology. Based on DBB, seedlings were most dormant at Lift 2 on November 24 after exposure to 189 hours below 10 degrees C and 93 hours below 6.7 degrees C. Mitotic activity in the apical meristem was at its lowest 23 days later at Lift 3, possibly indicating the period when seedlings are most resistant to transplanting stresses. Multiple wrenching resulted in a slight shift in the dormancy cycle as wrenched seedlings set bud sooner in the nursery and broke bud sooner at the planting site in the spring than control seedlings. This implies that wrenched seedlings can be successfully lifted from the nursery earlier and will initiate spring shoot growth earlier than control seedlings.

Journal Article↗
PubMed2002

The effect of chin lift, jaw thrust, and continuous positive airway pressure on the size of the glottic opening and on stridor score in anesthetized, spontaneously breathing children.

UNLABELLED: Chin lift and jaw thrust are two common maneuvers used to improve the patency of the upper airway during general anesthesia. We investigated the effect of these maneuvers combined with continuous positive airway pressure (CPAP) on the size of glottic opening and on stridor score. Forty children, aged 2--9 yr, premedicated with midazolam and spontaneously breathing end-tidal 1% halothane and equal parts of nitrous oxide and oxygen, were studied. A flexible fiberoptic bronchoscope was placed via mask and one nostril to the level of the junction of the soft palate and oropharynx. Video recordings and simultaneous stridor scores were obtained during six conditions: 1) chin unsupported, 2) manual chin lift, 3) chin lift and CPAP 10 cm H(2)O, 4) repeat chin unsupported, 5) manual jaw thrust, and 6) jaw thrust and CPAP 10 cm H(2)O. Videos were analyzed to determine the percentage of glottic opening (POGO) score. POGO score increased (P < 0.05) in Conditions 2, 3, 5, and 6. With increasing POGO score there was a decrease in stridor score (P < 0.05). IMPLICATIONS: Chin lift and jaw thrust maneuvers combined with continuous positive airway pressure improve the view of the glottic opening as viewed by flexible nasal laryngoscopy and decrease stridor in anesthetized, spontaneously breathing children.

Anesthesia, General↗
PubMed1995

Mask lift and facial aesthetic sculpturing.

Paul Tessier started the great adventure of sculpturing the malformed face more than 30 years ago. Key procedures such as subperiosteal dissection and lifting of the facial mask, bone grafting from a cranial site of harvest, and lateral canthopexies have been utilized and have withstood the trial of time in thousands of patients. The mask lift with facial aesthetic sculpturing, a newcomer in aesthetic surgery, is an extrapolation of these craniofacial procedures. It is a different and revolutionary approach to the aging face that seeks to normalize, rejuvenate, and embellish the face through a subperiosteal lift of the facial mask and transformation of the underlying structures. Facial aesthetic sculpturing refers to the aesthetic sculpturing of the facial skeleton. It allows us to equilibrate the components of a malformed face and normalize it by osteotomies, displacements in three dimensions, and bone overgrafting; to normalize the forms of an unattractive face and to embellish it by harmonization of the skeletal volume; and to restore the forms of an aging face and to rejuvenate it by augmenting resorbed bone, reducing hypertrophic bone, and lifting the facial mask. My experience includes 350 patients operated on from 1981 to 1992, of these, 200 cases were purely aesthetic, 150 functional. The complications encountered have been few. The technique described offers an appropriate response to the different problems of aging and embellishment of a face, whether for reequilibration of osseous volumes or for sagging of soft tissues of the superior two-thirds of the face. Facial aesthetic sculpturing finds application also in some malformations and acquired deformities and in young faces with unsightly features.

Aged↗