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[Polypoid eosinophilic granuloma of the small intestine (author's transl)].

The case of a circumscribed polypoid eosinophilic granuloma of the small intestine is reported. The tumor caused an intussusception with consecutive ileus. After resection of the involved bowels the patient was healed. No allergic history was found. The morphology, clinical features, and the therapy of this type of tumor is discussed and the relationship to the Histocytosis X is emphasized.

Adult↗

Colorectal cancer in rural Nebraska.

A case-control interview study of colorectal cancer was conducted in two rural counties of eastern Nebraska to determine reasons for the elevated colon cancer mortality rates during 1950 to 1969. Comparison of the information provided by 86 colorectal cancer cases and 176 matched controls (or their next of kin) revealed an increased risk among persons of Czech background, with persons of Bohemian and Moravian extraction predominating in this area. The data suggest an interaction between Bohemian ancestry and certain dietary patterns in the pathogenesis of colon cancer in this region. Colon cancer risk was elevated among commercial beer drinkers regardless of their ethnic background, although Bohemians reported heavier consumption. An excess risk was also associated with intestinal polyps, reported more often by Moravians, and with familial occurrence of gastrointestinal and other cancers. Since 1969, the mortality and incidence rates for colon cancer in this area have declined, possibly as a consequence of acculturation of the American-born descendants of Czech immigrants.

Age Factors↗

[Behavior of the mucosa of the large intestine following definite urinary diversion].

Multiple biopsies of the mucous and submucous membranes were taken from 50 patients with definitive diversion of urine using the large intestine and evaluated. The varying behaviour of the membranes in connection with uretero- sigmoidostomies , cysto- sigmoidostomies and rectal bladders is discussed. The reactions of the mucous membrane in connection with uretero-intestinal anastomosis are time-dependent. The most serious changes in the mucous membrane occurred in connection with rectal bladders.

Adolescent↗

[Traditional and selective radiological study of the small intestine. Current state and prospects].

The author, having noted that in radiology the small bowel is frequently ignored in comparison with the other digestive areas, proposes a "contract" examination of the digestive tract. Such a method, involving the acceleration of the transit induced by two metoclopramide tablets administered a few minutes before the examination, allows the small intestine to be included in the traditional investigations of the digestive system and, therefore, its complete visualization. Thus, it is possible to perform a larger and more detailed study of the under-evaluated jejunal and ileal pathology. Radiodiagnostic problems which cannot be adequately interpreted by the "contract" examination should be clarified by enteroclysis, the latter being considered a selective method.

Barium Sulfate↗

Radiologic diagnosis of Crohn disease (with emphasis on its early manifestations).

Crohn disease can affect any part of the gastrointestinal tract. The early manifestations of the disease are readily recognizable in the colon if double-contrast technique is employed. Small bowel and gastroduodenal involvement in the early stages have been less frequently identified, but enteroclysis and double-contrast UGI examination have yielded encouraging results. There is some evidence that failure to utilize the double-contrast barium enema and enteroclysis contributes to delay in diagnosis of Crohn disease. Use of these more sophisticated techniques is encouraged. As follow-up radiography in Crohn disease appears less indicated than previously considered, it is particularly important that initial assessment employs the most sensitive and accurate radiographic techniques available.

Adult↗