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Temporal trends in prevention of venous thromboembolism following primary total hip or knee arthroplasty 1996-2001: findings from the Hip and Knee Registry.

BACKGROUND: The Hip and Knee Registry is an observational database comprising data on practices of US orthopedic surgeons during 1996 to 2001. We examined trends in the use of prophylaxis for venous thromboembolism (VTE) among patients who underwent primary total hip arthroplasty (THA) or total knee arthroplasty (TKA). METHODS: Data on 9,327 THA and 13,846 TKA patients were submitted between 1996 and 2001 by 464 orthopedic surgeons from 319 hospitals in 42 of the United States. RESULTS: During 1996 to 2001, 44% of THA patients and 38% of TKA patients were male, and 93% and 92% were white, respectively. The median age of THA and TKA patients increased from 66 to 68 years and 68 to 69 years, respectively, between 1996 and 2001 (p < 0.001), while the mean length of hospital stay decreased from 4.7 to 3.7 days and 4.5 to 3.7 days, respectively (p < 0.001). Use of spinal or epidural anesthesia increased from 34 to 46% for THA and 43 to 54% for TKA patients (p < 0.001). One or more types of thromboprophylaxis were administered to 99% of patients. The following were the most common types of thromboprophylaxis: elastic stockings (61% and 58%), warfarin (56% and 53%), low-molecular-weight heparin (38% and 40%), and intermittent pneumatic compression (35% and 32%) in THA and TKA patients, respectively. Aspirin was used for thromboprophylaxis in 4% of THA and 7% of TKA patients. One or more type of in-hospital prophylaxis matching the 2001 American College of Chest Physicians (ACCP) recommendations were administered to 89% of THA and 91% of TKA patients between 1996 and 2001. During this period, in-hospital use of ACCP prophylaxis recommendations increased from 88 to 94% following THA (p < 0.001). This increase was also observed for prophylaxis administered to TKA patients, although this did not reach statistical significance. CONCLUSIONS: Recent trends in the management of patients undergoing THA and TKA in the United States, including shorter lengths of hospital stay and increased use of spinal/epidural anesthesia, present a challenge to orthopedic surgeons who wish to provide their patients with effective prophylaxis for VTE. Despite these challenges, nearly all surgeons participating in the Hip and Knee Registry are providing types of prophylaxis consistent with evidence-based consensus recommendations. Although there are concerns regarding increased bleeding risk due to the use of anticoagulants in patients receiving spinal/epidural anesthesia, there was a significant increase in the use of spinal/epidural anesthesia between 1996 and 2001. During this same period, the proportion of patients receiving spinal/epidural anesthesia who were also administered anticoagulants as prophylaxis increased significantly.

Aged↗

Patient-related risk factors for early revision of total hip replacements. A population register-based case-control study of 674 revised hips.

In this population register-based, matched case-control study, we assessed patient-related factors and early risk of revision after total hip replacement (THR). Information was obtained via a mall survey among patients reported to the Norwegian Arthroplasty Register during the period 1987-1993. The study included 674 revised hips, as cases, and 1,343 hips with a primary operation only, as controls. Completed questionnaires were received from 81% of the 2,017 individual cases and controls. We identified a set of patient-related factors associated with poor THR prognosis. Increasing weight was a risk factor among male patients older than 67 years who were more than 1.77 m tall (p = 0.01). Smoking had no overall effect, but former heavy smokers had an increased risk of 2.8 compared to never-smokers. Alcohol intake was associated with an increased risk of dislocation. Revision due to infection was commoner among patients taking anti-diabetic drugs (OR = 14) than among patients taking no medication. An increased overall revision risk was found among patients using systemic steroids (OR = 2.8) or local pulmonary steroids (OR = 6.0). The risk also increased in male patients performing regular exercise before the primary operation (OR = 2.6), and in female patients of working-age doing heavy work (OR = 1.9).

Adolescent↗

Polyethylene wear with an entirely HA-coated total hip replacement: 79 hips followed for 5 years.

We measured the eccentricity of the femoral head in the metal backing annually during 5 years in 79 consecutive total hip replacements (73 patients). The mean age of the patients was 57 (32-73) years and the female/male ratio 63/22. The prostheses were entirely coated with hydroxyapatite. Modular 32 mm stainless steel heads and hemispherical, self-tapping screw cups with polyethylene liners were used. We found accelerating eccentricity throughout the observation period. The mean eccentricity at 5 years was 0.71 mm (95% CI 0.53-0.90), resulting in a mean eccentricity rate of 0.14 mm (0.11-0.18) per year. The 5-year eccentricity was 0.5 mm or less in 45 hips and more than 1.5 mm in 13 hips, 2 in the latter group apparently having worn through the polyethylene liner. The true wear may be twice as great. The use of 32 mm stainless steel heads and thin polyethylene inlays may have aggravated the wear problems. These HA-coated prostheses must all be checked regularly, so that cases with excessive polyethylene wear can be reoperated on before wear-through of the liner.

Adult↗

Low IGF-I levels in hip fracture patients. A comparison of 20 coxarthrotic and 23 hip fracture patients.

We measured total body bone density and body composition with dual energy x-ray absorptiometry in 43 elderly patients, 23 with hip fracture and 20 with coxarthrosis, after surgery and after 6 months. Insulin-like growth factor-1 (IGF-I), a polypeptide known to affect bone metabolism, and two of its binding proteins (IGFBP-1, IGFBP-3) were measured preoperatively and after 6 months. Normal serum IGF-I levels are dependent on adequate nutrition and normal secretion of growth hormone (GH). We found consistently lower levels of IGF-I and IGFBP-3 and a tendency to higher levels of IGFBP-1 in the patients with hip fractures, who also had a lower total body mass, lower fat mass and bone mineral density than the coxarthrosis group, indicating a more catabolic state in the patients with hip fracture, even 6 months after the trauma.

Absorptiometry, Photon↗

Modular cementless total hip arthroplasty for hip infection sequelae.

Childhood hip infection may produce significant anatomical deformations leading to the premature onset of secondary osteoarthritis. Total hip arthroplasty (THA) in these patient populations can be technically challenging and has been associated with high complication rates. This article reports the results of 58 cementless THAs with use of a modern implant design. The complication rate, including one recurrent infection, was relatively low. Cementless THA with use of a modular stem coupled with a metal-backed socket was found to be an effective and reliable treatment option for patients with the late sequelae of infective hip arthritis.

Adolescent↗

[Hip joint deformity caused by osteochondrosis in the course of treatment of congenital dysplasia of the hip].

A series of 73 patients with avascular necrosis complicating surgical or nonsurgical treatment for congenital hip dysplasia is presented. The femoral head, neck and subcapital growth plate has been damaged in all cases. A-P radiographs of proximal femur revealed three types of growth disturbances: lateral, medial and total one. Localization of growth plate damage determined the type of growth disturbances. Mutual features for all types were: shortening of the femoral neck and growth disproportion between femoral head and greater trochanter. In 43 hips the greater trochanter grew over the femoral head and constituted the most proximal part of the femur (trochanter altus). Growth disturbances of the acetabulum coexisted (primary and secondary acetabular dysplasia). Radiological parameters of deformed hips have been compared with normal values.

Acetabulum↗

Requirement for total hip arthroplasty: an outcome measure of hip osteoarthritis?

OBJECTIVE: To assess if total hip arthroplasty (THA) is a valid outcome measure of hip osteoarthritis (OA), in respect to clinical and radiological assessments. METHODS: A prospective 3 year study of patients who had painful hip OA with an initial radiographic joint space width > or =1 mm at the narrowest point. Dependent variable was THA. Patient data including body mass index, OA structural severity by radiograph, OA symptomatic severity (pain, function), and OA localization were recorded at entry. Pelvic radiographs were obtained before THA, when available, and once yearly during the study. RESULTS: During the study 106 of 506 patients underwent THA. Risk was estimated (Kaplan-Meier method) to be 8+/-1, 16+/-2, and 23+/-2% after 1, 2, and 3 years, respectively. Factors predisposing to requirement for surgery were: age > or =70 years, female sex, superolateral migration of the femoral head, joint space width <2 mm, Kellgren-Lawrence grade > or =3, pain (visual analog scale) > or =50 mm, and Lequesne index > or =10 with a relative risk of 1.65, 1.71, 1.96, 1.85, 1.89, 1.86, and 2.59, respectively. Mean change in joint space width was 0.22+/-0.50 vs 0.97+/-1.35 mm/year in patients without and with THA, respectively (p<0.0001). Changes in radiological joint space width during the first year were highly predictive of requirement for THA during the 2 following years (risk of 5, 13, 25, and 79% in patients with a radiological joint space width worsening during the first year of 0, < or =25, >25 and < or =50, and >50%, respectively). CONCLUSION: These data suggest that THA could be considered as a valid outcome measure in OA. However, further studies should be conducted in other countries with different health care systems to evaluate the inter-country reliability of this measurement.

Aged↗

A composite index for total hip arthroplasty in patients with hip osteoarthritis.

OBJECTIVE: We propose a composite index for considering total hip arthroplasty (THA) in hip osteoarthritis (OA). METHODS: We carried out a 3 year longitudinal study of patients with painful hip OA from 137 centers. Clinical data were collected at baseline and every 3 months; radiographs were taken at entry and each year. The decision to have surgery was made by the patient, the rheumatologist, and the surgeon, with no reference to outcome measures. Statistical analysis included discrete Cox analysis with time dependent covariates, on 3 month interval grouped data. The dependent variable was THA during the 3 months following the evaluated visit. Time dependent covariates collated at each evaluated visit included radiological joint space width (JSW), percentage decrease in JSW during the year preceding, patient's global assessment. Lequesne index, pain, and nonsteroidal antiinflammatory drug and analgesic intake. We compared 2 analyses differing in symptomatic variables entered: values obtained at a single time point vs mean values between 2 visits at a 3 month interval. Selection of the index was based on the best combination of variables to predict occurrence of THA. RESULTS: Of the 508 patients recruited for study, 42 were excluded. During the 3 year followup, 75 patients underwent THA. Symptomatic, therapeutic, and radiological variables were included in the index resulting from the 2 analyses. Based on the selected cutoff, the positive and negative predictive values for occurrence of THA in the 2 years following were 54.3 and 90.6%, respectively (single point model), and 52.9 and 86.7%, respectively (model using mean values of symptomatic variables between 2 visits). CONCLUSION: The poor positive predictive value of the composite indices obtained in this study suggests that there are other unmeasured factors determining access to surgery. On the other hand, the high negative predictive values suggest that these composite measures should be used by clinicians to determine which patients should not be referred to THA.

Aged↗

[Development and formation of the hip joint in children with surgically treated congenital hip dislocation].

The aim of this paper was to evaluate the development of different elements of the hip joint after surgical treatment, depending on age, anatomic conditions and degree of dysplasia at the time treatment was implemented. 100 hip joints were evaluated in 76 children treated because of congenital hip dislocation with the Dega or Chiari method in the years 1988-1993, according indication proposed during the XXVI Conference of the Polish Orthopedic Society. Age of patients at the time of surgery ranged from 2.5 to 7.5 years. There were 62 girls and 14 boys. The Dega method was implemented in 85 joints and the Salter method in 12 joints. Follow-up period ranged from 5 to 10 years. The best results were obtained in children who underwent surgery before 4 years of age.

Age Factors↗

Imaging pediatric hip disorders and residual dysplasia of adult hips.

The application of newer imaging modalities such as ultrasound, CT, and MR imaging has made a major contribution to the understanding of pediatric hip disorders. Multiplanar imaging has been a major advancement in the depiction of the complex hip joint anatomy. Direct visualization of cartilage in the immature joint is now possible with MR imaging. Sophisticated computer software programs allow three-dimensional reconstruction of the joint from CT and MR data. Manipulation of three-dimensional images allows preoperative simulation of proposed surgical reorientation of hips with deformity resulting from dysplasia and Legg-Calvé-Perthes disease.

Adult↗

Severity of hip dysplasia and loosening of the socket in cemented total hip replacement. A long-term follow-up.

We have assessed the long-term results of 292 cemented total hip replacements which were performed for developmental dysplasia of the hip in 206 patients. The mean age of the patients at operation was 42.6 years (15.9 to 79.5) and most (202) were women. The severity of dysplasia was graded according to both the Crowe and the Hartofilakidis classifications. A 22.25-mm Charnley head was always used and the acetabular components were inserted with cement into the true acetabulum. Bone grafting of the acetabulum, using the patient's own femoral head, was performed on 48 occasions. At a mean follow-up of 15.7 years (2.2 to 31.2) the overall survival of the acetabular component was 78%. The main cause of revision was aseptic loosening (88.3%). The rate of survival at 20 years based on the Hartofilakidis classification was 76% in the dysplastic, 55% in the low-dislocation and 12% in the high-dislocation groups and on the Crowe classification, 72.7% for group I, 70.7% for group II, 36.7% for group III and 15.6% for group IV. There was no statistical correlation between bone grafting of the acetabulum and survival of the acetabular component. This study has shown a higher rate of failure of the acetabular component with increasing severity of hip dysplasia.

Adolescent↗

The European school of total hip arthroplasty and 35 years of total hip arthroplasty in the Czech Republic.

The development of the European total hip arthroplasty in the sixties of 20th century is associated mainly with the names of G. K. McKee, J. Charnley and M. E. Muller. The SICOT meeting in Paris in 1966 introduced THA as a new method of treatment of osteoarthritis of the hip and paved the way for the commercialization of the manufacturing of prostheses. The success of this method consisted primarily in the fixation of individual components by bone cement and application of metal-to-polyethylene and metal-to-metal joints. The book presents these historical events as they have been reflected in the development of THA in the countries of the former Czechoslovakia and in the development of implants of domestic provenance. The development of THA in the former Czechoslovakia started in 1969 and was based on the Swiss school established by M. E. Muller. The Muller component with the "banana-shaped" stem was implanted using the Watson-Jones approach, the proximal femur canal was prepared by a rasp and the Palacos cement was used. This prosthesis served also as the model for the first Czech implant Poldi-Cech of I generation (the Chirulen cup available in three sizes, the "banana- shaped" femoral component with a 32 mm head-diameter and 130 degree neck-shaft angle) the development of which started in 1969 and the serial production began in 1972 in the Poldi Kladno steel company. Fatigue fractures of the "banana-shaped" stem led to the development of the concept of a femoral component with an "anatomical" stem. In Switzerland, this concept was developed by B. G. Weber. In the former Czechoslovakia the development of a new femoral component with an "anatomical" stem following the shape of the intramedullary canal with an ovoid profile and without sharp edges started in 1972. Due to the incidence of fatigue fractures of the "banana-shaped"stem and material that was not sufficiently strong (steel used for the production of osteosynthetic components), 144 degree neck-shaft angle was chosen. Reduction of the effect of bending forces on the valgus stem had eliminated fatigue fractures. This Poldi-Cech prosthesis of II generation was provided in nine sizes. The diameter of the head remained the same. Three Chirulen cups were supplemented with a "flat" cup for implantation in a dysplastic acetabulum. The prosthesis was implanted with an exact instrument set (reamer for acetabular preparation, rasp for proximal femoral preparation, alignment device for accurate positioning of both the cup and the femoral component) with the use of the Palacos cement. The production of the Poldi-Cech prosthesis of II. generation started in 1974 with the fabrication of a monoblock. Since 1986 it has been developed into a modular system (14/16 cone) with the possibility to use a ceramic head of 32 mm diameter (only in the nineties the cone size was changed to 12/14 and the heads were provided also in the 28 mm diameter). The Poldi-Cech prosthesis of II generation with the "anatomical" stem has been implanted since 1974 (i. e. during 30 years) in more than 140 000 patients in the Czech and Slovak Republics. In the same year cemented monoblock hemiarthroplasty was developed on the same basis as THA using the same "anatomical" stem and 36 to 60mm head diameter. Until now more than 35,000 of these hemiarthroplasty systems have been implanted. Until 1992 the Poldi-Cech implant was practically the only available cemented total hip replacement in the former Czechoslovakia and retrospectively it may be considered a highly successful implant. In the authors' view, the further development of THA will lead in the following years to the use of implants proved by a long-term follow-up. Preference will be given to prostheses the implantation of which will require a minimal loss of the bone stock during primary surgery and which will allow a technically easy reimplantation. The continental Europe has been recently preferring hybrid prostheses while Scandinavia witnesses an evident increase in the number of implanted cemented prostheses to the detriment of the cementless and hybrid ones. Naturally, cementless prostheses will keep dominating in young patients.

Arthroplasty, Replacement, Hip↗

[Early complications and their causes in prosthetic hip joint replacement for coxarthrosis or median femoral neck fracture. Retrospective study of 3613 implanted hip joints].

In this retrospective descriptive study--including 3613 patients--type, frequency, and causes of early postoperative complications after total hip replacement are analysed. Operations were indicated in the majority of all cases by degenerative hip-joint diseases (n = 3214) and 399 cases by medial collum femoris fracture from adduction type (Garden III and IV). The frequency of early postoperative complications in total amount to 14.3%, the postoperative mortality was 2.3%. Total hip replacement in medial collum femoris fracture showed a significantly higher frequency of postoperative complications (4 times) and mortality (17 times). Complications in detail (cardiac, pulmonic, thromboembolic, early luxation, wound infection etc.) are represented and discussed in literature.

Adult↗

[Clinical and radiologic status of the hip joint in adolescents and children with late detection of anomalies of the hip joint].

The study analyzed 35 questionnaires (70 hips) with an overdue discovered anomaly of the hip joint. 32 cases (91.5%) were girls, 3 cases (8.5%) boys, while the relation of girls to boys was 10.6:1. The average age at the moment of discovery of the defect was 3.9 months and in the period of control 12-13 years. All the questionnaires were conservatively treated but it was not observed that the method of treatment had any influence on the final result. According to analysis of clinical and radiological parameters the authors accepted the thought that these hips should be followed up until the end of their growth, and when an indication for operative treatment has been set it should take care about the development of the acetabulum as well as the shape of the proximal edge of the femur and the orientation of the ilium bone.

Adolescent↗

Congenital dislocation of the hip treated by total hip arthroplasty.

Thirty-two total hip arthroplasties (THAs) were performed on 26 severely incapacitated patients with congenital dislocation of the hip. The arthroplasty technique varied with the problems encountered, but the cup was always placed in the true acetabulum. In 19 cases, femoral head autografts were transplanted. The overall results were satisfactory. Roentgenologic evaluation of the bone grafts showed no nonunion or secondary displacement. Nineteen previously invalid patients now lead normal lives. Five patients are minimally incapacitated and only two were unimproved by the operation. THA with autogeneic grafts to deepen the acetabulum is recommended whenever a congenital dislocation of the hip in an adult is associated with severe pain.

Adolescent↗

Association of preoperative hip motion and sciatic nerve palsy following total hip arthroplasty.

This retrospective study investigated the possible correlation between preoperative hip range of motion (ROM) and postoperative sciatic nerve palsy. From 1971 to 1987, 12 patients with partial sciatic nerve palsies subsequent to total hip arthroplasty (THA) without known etiologies were identified. During this same period a random sample of 340 patients with 373 palsy-free THAs were also identified. To exclude possible bias from revision patients (revision procedures are reported to have an increased incidence of postoperative nerve palsies), the patients were divided into three groups: (1) all THAs; (2) primary THAs; and (3) revision THAs. The preoperative hip motions studied were flexion, abduction, adduction, internal rotation, and external rotation. Analysis of the data showed no correlation between limited ROM preoperatively and the risk of postoperative nerve palsy for any of the three groups.

Hip Joint↗

Prophylactic use of a hip cast-brace following primary and revision total hip arthroplasty.

A hip cast-brace was routinely applied to 67 patients undergoing 37 revision and 30 primary total hip arthroplasties. In the revision group, 78% of the patients were discharged by the tenth postoperative day; the average period in the cast-brace was 23 days. One patient developed deep venous thrombosis. Dislocation occurred in three patients who had undergone previous revision total hip arthroplasties. Of these three patients, one dislocated while wearing the cast-brace. In the primary group, 72% of the patients were discharged by the eighth postoperative day and average time in the cast-brace was 15 days. One developed deep venous thrombosis; no dislocations occurred.

Braces↗

Natural history of congenital hip dislocation (CDH) and hip dysplasia.

For normal development of the hip joint to occur, there must be a delicate, genetically determined balance between growth of the acetabular and triradiate cartilages and a well-centered femoral head. This balance may be profoundly affected by the intrauterine environment. Without treatment, it is uncertain how many dysplastic, unstable hips will retain their dysplastic features throughout life. The natural history of untreated complete dislocation varies considerably and is affected by societal considerations. There may be little, if any, functional disability in many cases. Significant roentgenographic degenerative disease and poor clinical results, however, may develop in completely dislocated hips with well developed false acetabulae. In unilateral cases, ipsilateral knee deformity and pain may develop. Congenital subluxations have a particularly poor long-term outcome. A significant percentage of these patients have roentgenographic degenerative joint disease and clinical disability. The age of symptom onset and roentgenographic degenerative joint disease is related to the amount of subluxation and dysplasia. The natural history of acetabular dysplasia in the absence of subluxation is difficult to predict. Physical signs may be absent, and the diagnosis only established with symptom onset or as an incidental roentgenographic finding. While degenerative joint disease may ensue, current roentgenographic parameters are not predictive.

Adult↗